Sergey I Nikolaev

Sergey I Nikolaev

UNVERIFIED PROFILE

Are you Sergey I Nikolaev?   Register this Author

Register author
Sergey I Nikolaev

Sergey I Nikolaev

Publications by authors named "Sergey I Nikolaev"

Are you Sergey I Nikolaev?   Register this Author

26Publications

652Reads

42Profile Views

Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain.

N Engl J Med 2018 04;378(16):1561-1562

Krembil Research Institute, Toronto, ON, Canada

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1802190DOI Listing
April 2018

Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain.

N Engl J Med 2018 01 3;378(3):250-261. Epub 2018 Jan 3.

From the Department of Genetic Medicine and Development, University of Geneva Medical School (S.I.N., X.B., S.E.A.), Service of Genetic Medicine, University Hospitals of Geneva (S.I.N., S.E.A.), and iGE3, Institute of Genetics and Genomics of Geneva (S.E.A.) - all in Geneva; the Department of Fundamental Neurobiology, Krembil Research Institute (S.V., M.T., I.R.), Toronto General Hospital Research Institute (E.B., N.K., P.V.D., J.E.F.), the Department of Pathology (T.-R.K.), the Division of Neurosurgery, Department of Surgery (V.M.P., T.K., H.A.-B., T.T., T.V., G.Z., M.T., I.R.), and the Joint Division of Medical Imaging, Department of Medical Imaging (V.M.P., T.K.), Toronto Western Hospital, University Health Network, the Department of Laboratory Medicine and Pathobiology, University of Toronto (E.B., N.K., P.V.D., T.-R.K., J.E.F.), and the Heart and Stroke Richard Lewar Centre of Excellence in Cardiovascular Research (E.B., N.K., P.V.D., J.E.F.) - all in Toronto; the Department of Molecular Medicine, AIV Institute, University of Eastern Finland (S.J., B.R.J., S.S., S.Y.-H., J.F.), and the Hemorrhagic Brain Pathology Research Group, Department of Neurosurgery and NeuroCenter (S.J., B.R.J., S.S., T.R., J.F.), and the Department of Pathology (T.R.), Kuopio University Hospital - all in Kuopio, Finland; and the Cardiovascular Research Institute and the Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston (A.M.H., J.D.W.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1709449DOI Listing
January 2018

Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand.

Genome Res 2017 08 16;27(8):1336-1343. Epub 2017 May 16.

Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow 127994, Russia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.219915.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538550PMC
August 2017

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication.

Genome Res 2016 Feb 11;26(2):174-82. Epub 2016 Jan 11.

Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland; Institute of Genetics and Genomics in Geneva, 1211 Geneva, Switzerland; Service of Genetic Medicine, University Hospitals of Geneva, 1211 Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.197046.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728370PMC
February 2016

Gene age predicts the strength of purifying selection acting on gene expression variation in humans.

Am J Hum Genet 2014 Dec;95(6):660-74

Department of Genetic Medicine and Development, University of Geneva Medical School, 1 Rue Michel-Servet, 1211 Geneva, Switzerland; Institute of Genetics and Genomics in Geneva, 1211 Geneva, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2014.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259975PMC
December 2014

Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations.

Nat Commun 2014 Aug 8;5:4654. Epub 2014 Aug 8.

1] Department of Genetic Medicine and Development, University of Geneva Medical School, 1 rue Michel Servet, Geneva 1211, Switzerland [2] IGE3 institute of Genetics and Genomics of Geneva, 1 rue Michel Servet, Geneva 1211, Switzerland [3].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms5654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665216PMC
August 2014

The Not3/5 subunit of the Ccr4-Not complex: a central regulator of gene expression that integrates signals between the cytoplasm and the nucleus in eukaryotic cells.

Cell Signal 2013 Apr 29;25(4):743-51. Epub 2012 Dec 29.

Dpt of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, 1 Rue Michel Servet, 1211 Genève 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellsig.2012.12.018DOI Listing
April 2013

Purifying selection in mammalian mitochondrial protein-coding genes is highly effective and congruent with evolution of nuclear genes.

Mol Biol Evol 2013 Feb 14;30(2):347-55. Epub 2012 Sep 14.

Department of Genetic Medicine and Development, University of Geneva Medical School and iGE3 Institute of Genetics and Genomics of Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/molbev/mss219DOI Listing
February 2013

Deep phylogeny and evolution of slime moulds (mycetozoa).

Protist 2010 Jan 5;161(1):55-70. Epub 2009 Aug 5.

University of Oxford, Department of Zoology, South Parks Road, Oxford OX1 3PS, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.protis.2009.05.002DOI Listing
January 2010

Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development.

Am J Hum Genet 2008 Aug 24;83(2):208-18. Epub 2008 Jul 24.

Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Rue Michel-Servet 1, 1211 Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2008.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2495069PMC
August 2008

Life-history traits drive the evolutionary rates of mammalian coding and noncoding genomic elements.

Proc Natl Acad Sci U S A 2007 Dec 11;104(51):20443-8. Epub 2007 Dec 11.

Department of Genetic Medicine and Development, University of Geneva Medical School, 1 Rue Michel-Servet, 1211 Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0705658104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2154450PMC
December 2007

Phylogenomics reshuffles the eukaryotic supergroups.

PLoS One 2007 Aug 29;2(8):e790. Epub 2007 Aug 29.

Department of Zoology and Animal Biology, University of Geneva, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000790PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949142PMC
August 2007

Analysis of expressed sequence tags from a naked foraminiferan Reticulomyxa filosa.

Genome 2006 Aug;49(8):882-7

University of Geneva, Department of Zoology and Animal Biology, Geneva, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1139/g06-048DOI Listing
August 2006

Phylogenetic position of Multicilia marina and the evolution of Amoebozoa.

Int J Syst Evol Microbiol 2006 Jun;56(Pt 6):1449-58

Department of Evolutionary Biochemistry, AN Belozersky Institute of Physico-Chemical Biology, Moscow State University, Russia.

View Article

Download full-text PDF

Source
http://ijs.microbiologyresearch.org/content/journal/ijsem/10
Publisher Site
http://dx.doi.org/10.1099/ijs.0.63763-0DOI Listing
June 2006

The testate lobose amoebae (order Arcellinida Kent, 1880) finally find their home within Amoebozoa.

Protist 2005 Aug;156(2):191-202

Department of Evolutionary Biochemistry, A. N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, Russia.

View Article

Download full-text PDF

Source
August 2005

Molecular phylogenetic analysis places Percolomonas cosmopolitus within Heterolobosea: evolutionary implications.

J Eukaryot Microbiol 2004 Sep-Oct;51(5):575-81

Department of Evolutionary Biochemistry, A. N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, Russia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1550-7408.2004.tb00294.xDOI Listing
March 2005

The twilight of Heliozoa and rise of Rhizaria, an emerging supergroup of amoeboid eukaryotes.

Proc Natl Acad Sci U S A 2004 May 17;101(21):8066-71. Epub 2004 May 17.

A. N. Belozersky Institute of Physico-Chemical Biology, Department of Evolutionary Biochemistry, Moscow State University, Moscow 119992, Russia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0308602101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC419558PMC
May 2004