Publications by authors named "Sergei Doulatov"

28Publications

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development.

Cell Stem Cell 2018 04;22(4):575-588.e7

Stem Cell Program, Division of Hematology/Oncology, Manton Center for Orphan Disease Research, Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957284PMC
April 2018

Haematopoietic stem and progenitor cells from human pluripotent stem cells.

Nature 2017 05 17;545(7655):432-438. Epub 2017 May 17.

Stem Cell Transplantation Program, Division of Pediatric Hematology and Oncology, Dana-Farber Cancer Institute, Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature22370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872146PMC
May 2017

Autophagy: It's in Your Blood.

Dev Cell 2017 03;40(6):518-520

Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.devcel.2017.03.011DOI Listing
March 2017

CDK6 levels regulate quiescence exit in human hematopoietic stem cells.

Cell Stem Cell 2015 Mar 19;16(3):302-13. Epub 2015 Feb 19.

Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359055PMC
March 2015

Development. A stem cell perspective on cellular engineering.

Science 2013 Nov;342(6159):700-2

Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Manton Center for Orphan Disease Research, Howard Hughes Medical Institute, Children's Hospital Boston and Dana Farber Cancer Institute; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; Broad Institute; Harvard Stem Cell Institute; Boston, MA 02115, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1238363
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http://dx.doi.org/10.1126/science.1238363DOI Listing
November 2013

Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.

Cell Stem Cell 2013 Oct;13(4):459-70

Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Manton Center for Orphan Disease Research, Howard Hughes Medical Institute, Children's Hospital Boston and Dana Farber Cancer Institute; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA.

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http://dx.doi.org/10.1016/j.stem.2013.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888026PMC
October 2013

The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment.

Nat Immunol 2013 Jul 26;14(7):756-63. Epub 2013 May 26.

Campbell Family Institute for Cancer Research, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ni.2615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961471PMC
July 2013

Hematopoiesis: a human perspective.

Cell Stem Cell 2012 Feb;10(2):120-36

Division of Stem Cell and Developmental Biology, Campbell Family Institute for Cancer Research/Ontario Cancer Institute, Toronto, ON M5G 1L7, Canada.

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http://dx.doi.org/10.1016/j.stem.2012.01.006DOI Listing
February 2012

Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment.

Science 2011 Jul;333(6039):218-21

Division of Stem Cell and Developmental Biology, Campbell Family Institute for Cancer Research/Ontario Cancer Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1126/science.1201219DOI Listing
July 2011

Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.

Nature 2011 Jan;469(7330):362-7

Division of Stem Cell and Developmental Biology, Campbell Family Institute for Cancer Research/Ontario Cancer Institute, Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1038/nature09733DOI Listing
January 2011

Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development.

Nat Immunol 2010 Jul 13;11(7):585-93. Epub 2010 Jun 13.

Department of Stem Cell and Developmental Biology, Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ni.1889DOI Listing
July 2010

Engraftment of human hematopoietic stem cells is more efficient in female NOD/SCID/IL-2Rgc-null recipients.

Blood 2010 May 5;115(18):3704-7. Epub 2010 Mar 5.

Division of Stem Cell and Developmental Biology, Campbell Family Institute for Cancer Research/Ontario Cancer Institute, Toronto, ON, Canada.

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http://dx.doi.org/10.1182/blood-2009-10-249326DOI Listing
May 2010

The role of PLZF in human myeloid development.

Ann N Y Acad Sci 2009 Sep;1176:150-3

Division of Cell and Molecular Biology, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1749-6632.2009.04965.xDOI Listing
September 2009

PLZF is a regulator of homeostatic and cytokine-induced myeloid development.

Genes Dev 2009 Sep;23(17):2076-87

Division of Cell and Molecular Biology, University Health Network, Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1101/gad.1788109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751973PMC
September 2009

Diversity-generating retroelement homing regenerates target sequences for repeated rounds of codon rewriting and protein diversification.

Mol Cell 2008 Sep;31(6):813-23

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.molcel.2008.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703419PMC
September 2008

The C-type lectin fold as an evolutionary solution for massive sequence variation.

Nat Struct Mol Biol 2005 Oct 18;12(10):886-92. Epub 2005 Sep 18.

Department of Chemistry & Biochemistry, University of California at San Diego, La Jolla, California 92093, USA.

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http://www.nature.com/articles/nsmb992
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http://dx.doi.org/10.1038/nsmb992DOI Listing
October 2005

Tropism switching in Bordetella bacteriophage defines a family of diversity-generating retroelements.

Nature 2004 Sep;431(7007):476-81

Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/nature02833DOI Listing
September 2004

Plasmid-based reporter genes: assays for green fluorescent protein.

Methods Mol Biol 2003 ;235:297-304

Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, USA.

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http://dx.doi.org/10.1385/1-59259-409-3:297DOI Listing
April 2004

Reverse transcriptase-mediated tropism switching in Bordetella bacteriophage.

Science 2002 Mar;295(5562):2091-4

Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1126/science.1067467DOI Listing
March 2002