Publications by authors named "Serge Y Fuchs"

94Publications

The ssDNA-binding protein MEIOB acts as a dosage-sensitive regulator of meiotic recombination.

Nucleic Acids Res 2020 12;48(21):12219-12233

Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.

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December 2020

Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis.

Oncogene 2020 09 17;39(38):6129-6137. Epub 2020 Aug 17.

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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September 2020

Malignant cell-specific pro-tumorigenic role of type I interferon receptor in breast cancers.

Cancer Biol Ther 2020 Jul 7;21(7):629-636. Epub 2020 May 7.

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania , Philadelphia, PA, USA.

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July 2020

Age-Dependent Effects of Type I and Type III IFNs in the Pathogenesis of Infection and Disease.

J Immunol 2020 04 9;204(8):2192-2202. Epub 2020 Mar 9.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201; and

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April 2020

Cytochrome c oxidase dysfunction enhances phagocytic function and osteoclast formation in macrophages.

FASEB J 2019 08 7;33(8):9167-9181. Epub 2019 May 7.

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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August 2019

The PKR-Like Endoplasmic Reticulum Kinase Promotes the Dissemination of Myc-Induced Leukemic Cells.

Mol Cancer Res 2019 07 22;17(7):1450-1458. Epub 2019 Mar 22.

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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July 2019

Estrogen-dependent DLL1-mediated Notch signaling promotes luminal breast cancer.

Oncogene 2019 03 15;38(12):2092-2107. Epub 2018 Nov 15.

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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March 2019

Downregulation of the IFNAR1 chain of type 1 interferon receptor contributes to the maintenance of the haematopoietic stem cells.

Cancer Biol Ther 2017 Jul 5;18(7):534-543. Epub 2017 Jul 5.

a Department of Biomedical Sciences and Mari Lowe Center for Comparative Oncology , School of Veterinary Medicine, University of Pennsylvania , Philadelphia , PA , USA.

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July 2017

Expression of the IFNAR1 chain of type 1 interferon receptor in benign cells protects against progression of acute leukemia.

Leuk Lymphoma 2018 01 15;59(1):171-177. Epub 2017 May 15.

a Department of Biomedical Sciences , Mari Lowe Center for Comparative Oncology, School of Veterinary Medicine, University of Pennsylvania , Philadelphia , PA , USA.

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January 2018

PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma.

PLoS Genet 2016 Dec 15;12(12):e1006518. Epub 2016 Dec 15.

Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina, United States of America.

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December 2016

Therapeutic Elimination of the Type 1 Interferon Receptor for Treating Psoriatic Skin Inflammation.

J Invest Dermatol 2016 10 29;136(10):1990-2002. Epub 2016 Jun 29.

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:

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October 2016