Publications by authors named "Serge Gauthier"

99Publications

Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer's disease.

Brain 2020 Nov 19. Epub 2020 Nov 19.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awaa342DOI Listing
November 2020

Canadian Consensus Conference on Diagnosis and Treatment of Dementia (CCCDTD)5: Guidelines for management of vascular cognitive impairment.

Alzheimers Dement (N Y) 2020 11;6(1):e12056. Epub 2020 Nov 11.

Department of Medicine (Neurology) Hurvitz Brain Sciences Research Program LC Campbell Cognitive Neurology Unit Canadian Partnership for Stroke Recovery University of Toronto Toronto Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/trc2.12056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657196PMC
November 2020

Impact of p-tau181 and p-tau217 levels on enrolment for randomized clinical trials and future use of anti-amyloid and anti-tau drugs.

Expert Rev Neurother 2020 Oct 23. Epub 2020 Oct 23.

McGill Center for Studies in Aging , 6825 LaSalle Boulevard, Montreal, QC, Canada, H4H 1R3.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14737175.2020.1841637DOI Listing
October 2020

Topographical distribution of amyloid-β, tau and atrophy in behavioral / dysexecutive AD patients.

Neurology 2020 Oct 22. Epub 2020 Oct 22.

From the Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Canada.Department of Neurology and Neurosurgery, McGill University, Montreal, Canada.Montreal Neurological Institute, Montreal, Canada.Department of Biofunctional Imaging, Hamamatsu University School of Medicine, JapanMoCA Clinic and Institute, Montreal, CanadaDepartment of Psychiatry, McGill University, Montreal, CanadaDepartment of Radiochemistry, McGill University, Montreal, CanadaDepartment of Epidemiology and Biostatistics, McGill University, Montreal, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000011081DOI Listing
October 2020

Remote cognitive and behavioral assessment: Report of the Alzheimer Society of Canada Task Force on dementia care best practices for COVID-19.

Alzheimers Dement (Amst) 2020 22;12(1):e12111. Epub 2020 Sep 22.

Departments of Psychiatry, Clinical Neurosciences, and Community Health Sciences Cumming School of Medicine University of Calgary Calgary Alberta Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dad2.12111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507991PMC
September 2020

Agitation and impulsivity in mid and late life as possible risk markers for incident dementia.

Alzheimers Dement (N Y) 2020 6;6(1):e12016. Epub 2020 Sep 6.

Department of Clinical Neurosciences; and the Ron and Rene Ward Centre for Healthy Brain Aging Research; Hotchkiss Brain Institute University of Calgary Calgary Alberta Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/trc2.12016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507499PMC
September 2020

Pandemic Dementia Scarce Resource Allocation.

Can Geriatr J 2020 Sep 1;23(3):216-218. Epub 2020 Sep 1.

Departments of Neurology, Neurosurgery and Psychiatry, McGill University, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5770/cgj.23.457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458602PMC
September 2020

Trajectories of decline on instrumental activities of daily living prior to dementia in persons with mild cognitive impairment.

Int J Geriatr Psychiatry 2020 Sep 6. Epub 2020 Sep 6.

Institut universitaire de gériatrie de Montréal, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gps.5426DOI Listing
September 2020

Clinical and biomarker trajectories in sporadic Alzheimer's disease: A longitudinal study.

Alzheimers Dement (Amst) 2020 12;12(1):e12095. Epub 2020 Aug 12.

Department of Neurology and Institute of Neurology Huashan Hospital Shanghai Medical College Fudan University Shanghai China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dad2.12095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7421532PMC
August 2020

18F-MK-6240 PET for early and late detection of neurofibrillary tangles.

Brain 2020 Sep;143(9):2818-2830

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Alzheimer's Disease ResearchUnit, McGill University, Montreal, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awaa180DOI Listing
September 2020

Topographical distribution of Aβ predicts progression to dementia in Aβ positive mild cognitive impairment.

Alzheimers Dement (Amst) 2020 21;12(1):e12037. Epub 2020 Jun 21.

Translational Neuroimaging Laboratory Alzheimer's Disease Research Unit The McGill University Research Centre for Studies in Aging McGill University Montreal Quebec Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dad2.12037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306519PMC
June 2020

Non-Amyloid Approaches to Disease Modification for Alzheimer's Disease: An EU/US CTAD Task Force Report.

J Prev Alzheimers Dis 2020 Apr 6:1-6. Epub 2020 Apr 6.

12Gerontopole, INSERM U1027, Alzheimer's Disease Research and Clinical Center, Toulouse University Hospital, Toulouse, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14283/jpad.2020.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223540PMC
April 2020

Coronavirus epidemic and geriatric mental healthcare in China: how a coordinated response by professional organizations helped older adults during an unprecedented crisis.

Int Psychogeriatr 2020 Oct 9;32(10):1117-1120. Epub 2020 Apr 9.

Dementia Care and Research Center, Peking University Institute of Mental Health (Sixth Hospital), Beijing Dementia Key Lab, Beijing100191, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1041610220000551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184143PMC
October 2020

Dementia care during COVID-19.

Lancet 2020 04 30;395(10231):1190-1191. Epub 2020 Mar 30.

Dementia Care and Research Center, Peking University Institute of Mental Health (Sixth Hospital), Beijing Dementia Key Lab, Beijing 100191, China; NHC Key Laboratory of Mental Health, National Clinical Research Center for Mental Disorders (Peking University), Beijing, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(20)30755-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146671PMC
April 2020

APOEε4 potentiates the relationship between amyloid-β and tau pathologies.

Mol Psychiatry 2020 Mar 11. Epub 2020 Mar 11.

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41380-020-0688-6DOI Listing
March 2020

The continuum of care for dementia: needs, resources and practice in China.

J Glob Health 2019 Dec;9(2):020321

Dementia Care and Research Center, Peking University Institute of Mental Health (Sixth Hospital), Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7189/jogh.09.020321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925963PMC
December 2019

Brain Metabolic Dysfunction in Early Neuropsychiatric Symptoms of Dementia.

Front Pharmacol 2019 22;10:1398. Epub 2019 Nov 22.

The McGill University Research Centre for Studies in Aging, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphar.2019.01398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882863PMC
November 2019

Rasagiline, a monoamine oxidase B inhibitor, reduces in vivo [F]THK5351 uptake in progressive supranuclear palsy.

Neuroimage Clin 2019 13;24:102091. Epub 2019 Nov 13.

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, 6825 Boulevard LaSalle, Verdun, Montreal, QC H4H 1R3, Canada; Alzheimer's Disease Research Unit, Douglas Hospital, McGill University, Montreal, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.102091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889764PMC
September 2020

Dementia in China: epidemiology, clinical management, and research advances.

Lancet Neurol 2020 01 4;19(1):81-92. Epub 2019 Sep 4.

Innovation Center for Neurological Disorders, Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China; Beijing Key Laboratory of Geriatric Cognitive Disorders, Beijing, China; Clinical Center for Neurodegenerative Disease and Memory Impairment, Capital Medical University, Beijing, China; Center of Alzheimer's Disease, Beijing Institute for Brain Disorders, Beijing, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1474-4422(19)30290-XDOI Listing
January 2020

Users' perspectives on medical assistance in dying for persons with dementia.

Int J Geriatr Psychiatry 2019 07 29;34(7):905. Epub 2019 Apr 29.

Alzheimer Disease Research Unit, McGill Center for Studies in Aging, Montreal, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gps.5115DOI Listing
July 2019

Openness, inclusion, and respect in dementia research.

Lancet Neurol 2019 02;18(2):135-136

Douglas Mental Health University Institute, Montréal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1474-4422(18)30445-9DOI Listing
February 2019

Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer's Dementia.

Mol Neurobiol 2019 Jul 9;56(7):4916-4924. Epub 2018 Nov 9.

Translational Neuroimaging Laboratory (TNL), McGill Center for Studies in Aging (MCSA), Douglas Mental Health Research Institute, 6825, boul. LaSalle Blvd., Montréal, QC, H4H1R3, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12035-018-1405-1DOI Listing
July 2019

Consent recommendations for research and international data sharing involving persons with dementia.

Alzheimers Dement 2018 10 2;14(10):1334-1343. Epub 2018 Jul 2.

Department of Medical Genetics, University of Cambridge, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2018.05.011DOI Listing
October 2018

The influence of language and culture on cognitive assessment tools in the diagnosis of early cognitive impairment and dementia.

Expert Rev Neurother 2018 Nov 10;18(11):859-869. Epub 2018 Oct 10.

b Alzheimer's Disease Research Unit , The McGill University Research Centre for Studies in Aging , Montreal , Canada.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14737175.2018.1
Publisher Site
http://dx.doi.org/10.1080/14737175.2018.1532792DOI Listing
November 2018

Detection of mild cognitive impairment in middle-aged and older adults with obstructive sleep apnoea.

Eur Respir J 2018 11 1;52(5). Epub 2018 Nov 1.

Centre for Advanced Research in Sleep Medicine (CARSM), Hôpital du Sacré-Coeur de Montréal, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://erj.ersjournals.com/lookup/doi/10.1183/13993003.01137
Publisher Site
http://dx.doi.org/10.1183/13993003.01137-2018DOI Listing
November 2018

Optimal use of cholinergic drugs in Alzheimer's disease.

Brain 2018 09;141(9):e68

Alzheimer's Disease Research Unit, McGill University Research Center for Studies in Aging, Douglas Research Center and CIUSS de l'Ouest de l'Ile, Montreal, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awy204DOI Listing
September 2018

In vivo quantification of neurofibrillary tangles with [F]MK-6240.

Alzheimers Res Ther 2018 07 31;10(1):74. Epub 2018 Jul 31.

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, 6825 LaSalle Boulevard, Verdun, QC, H4H 1R3, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13195-018-0402-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069775PMC
July 2018

New thinking about thinking, part two. Theoretical articles for Alzheimer's & Dementia.

Alzheimers Dement 2018 06 26;14(6):703-706. Epub 2018 May 26.

Editor-in-Chief, Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Rockville, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2018.05.002DOI Listing
June 2018

Targeting Alzheimer's Disease at the Right Time and the Right Place: Validation of a Personalized Approach to Diagnosis and Treatment.

J Alzheimers Dis 2018 ;64(s1):S23-S31

McGill Center for Studies in Aging, Douglas Mental Health Research Institute, Montreal, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-179924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004905PMC
June 2019

Corrigendum to "Hippocampus and amygdala volumes from magnetic resonance images in children: Assessing accuracy of FreeSurfer and FSL against manual segmentation"[NeuroImage 129 (2016) 1-14].

Neuroimage 2018 06 21;173:1-2. Epub 2018 Feb 21.

McGill Centre for Studies in Aging, McGill University, Montreal, QC, Canada; Douglas Hospital Research Centre, Psychiatry Department, McGill University, Montreal, QC, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2018.02.009DOI Listing
June 2018

variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.

Neurol Genet 2018 Feb 30;4(1):e216. Epub 2018 Jan 30.

Translational Neuroimaging Laboratory (A.L.B., S.M., T.A.P., M.S., M.-S.K., P.R.-N.), and Alzheimer's Disease Research Unit (S.G., P.R.-N.), McGill University Research Centre for Studies in Aging, Montreal, Canada; CAPES Foundation (A.L.B.), Ministry of Education of Brazil, Brasília, Brazil; Rush Alzheimer's Disease Center (L.Y., D.A.B.), Rush University Medical Center, Chicago, IL; Department of Decision Sciences (A.L.), HEC Montreal, Montreal, Canada; Department of Epidemiology (A.L.), Biostatistics & Occupational Health, McGill University, Montreal, Canada; Department of Neurology and Neurosurgery (G.A.R., J.P., P.R.-N.), Douglas Hospital Research Centre (J.P., P.R.-N.), and Department of Psychiatry (J.P.), McGill University, Montreal, Canada; and Montreal Neurological Institute (G.A.R., P.R.-N.), Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/NXG.0000000000000216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820598PMC
February 2018

Dementia clinical trial implications of mild behavioral impairment.

Int Psychogeriatr 2018 02;30(2):171-175

Department of Clinical Neurosciences,Ron and Rene Ward Centre for Healthy Brain Aging,Hotchkiss Brain Institute,University of Calgary,Calgary,Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1041610218000042DOI Listing
February 2018

Anosognosia predicts default mode network hypometabolism and clinical progression to dementia.

Neurology 2018 03 14;90(11):e932-e939. Epub 2018 Feb 14.

From the Translational Neuroimaging Laboratory (J.T., K.P.N., T.A.P., S.M., M.S.K., H.S., M.S., A.L.B., P.R.-N.) and Alzheimer's Disease Research Unit (K.P.N., S.G., P.R.-N.), The McGill University Research Centre for Studies in Aging, Montreal, Canada; Department of Neurology (K.P.N.), National Neuroscience Institute, Singapore; Reference Center for Biological Markers of Dementia (BIODEM) (H.S.), University of Antwerp, Belgium; Center for Mind and Brain (I.C.W.), University of Sydney, Australia; Douglas Hospital Research Centre (V.N.), Department of Psychiatry (V.N.), and Department of Neurology and Neurosurgery (P.R.-N.), McGill University; and Montreal Neurological Institute (P.R.-N.), Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000005120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858945PMC
March 2018

Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer's disease.

Eur J Nucl Med Mol Imaging 2018 06 2;45(6):1021-1030. Epub 2018 Feb 2.

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC room 3149, Montreal, QC, H4H 1R3, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00259-018-3933-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915512PMC
June 2018

Comparative effect of statins on the risk of incident Alzheimer disease.

Neurology 2018 01 15;90(3):e179-e187. Epub 2017 Dec 15.

From the Centre for Clinical Epidemiology (L.S., C.R., S.D., S.S., P.B.), Jewish General Hospital; McGill University Research Centre for Studies in Aging (S.G.), Douglas Mental Health University Institute; and Departments of Neurology and Neurosurgery (C.R.) and Medicine and Epidemiology, Biostatistics, and Occupational Health (C.R., S.S., P.B.), McGill University, Montreal, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000004818DOI Listing
January 2018

Characterizing biomarker features of cognitively normal individuals with ventriculomegaly.

Alzheimers Dement (Amst) 2018 5;10:12-21. Epub 2017 Sep 5.

Alzheimer's Disease Research Unit, The McGill University Research Centre for Studies in Aging, McGill University, Montreal, Canada.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S23528729173004
Publisher Site
http://dx.doi.org/10.1016/j.dadm.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678356PMC
September 2017

Progress in transnational scientific and ethics review: Commentary on the proposal for a single North American review board for research on dementia.

Alzheimers Dement 2018 01 28;14(1):115-116. Epub 2017 Oct 28.

Comité central d'éthique de la recherche du ministre des Services de santé et des Services sociaux du Québec, Montréal, Canada.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15525260173377
Publisher Site
http://dx.doi.org/10.1016/j.jalz.2017.10.001DOI Listing
January 2018

The prevalence and biomarkers' characteristic of rapidly progressive Alzheimer's disease from the Alzheimer's Disease Neuroimaging Initiative database.

Alzheimers Dement (N Y) 2017 Jan 9;3(1):107-113. Epub 2017 Feb 9.

Alzheimer's Disease Research Unit, McGill Centre for Studies in Aging, McGill University, Douglas Institute, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.trci.2016.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651370PMC
January 2017

Treatment effects of Ginkgo biloba extract EGb 761® on the spectrum of behavioral and psychological symptoms of dementia: meta-analysis of randomized controlled trials.

Int Psychogeriatr 2018 03 21;30(3):285-293. Epub 2017 Sep 21.

Alzheimer Disease Research Unit,Memory Clinic,McGill Centre for Studies in Aging,McGill University,Verdun,Quebec,Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1041610217001892DOI Listing
March 2018

Identifying incipient dementia individuals using machine learning and amyloid imaging.

Neurobiol Aging 2017 11 11;59:80-90. Epub 2017 Jul 11.

Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging (MCSA), Douglas Research Institute, McGill University, Montreal, Quebec, Canada; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada; McGill University Research Centre for Studies in Aging (MCSA), Douglas Research Institute, McGill University, Montreal, Quebec, Canada; Douglas Research Institute, McGill University, Montreal, Quebec, Canada; Department of Psychiatry, McGill University, Montreal, Quebec, Canada; Department of Neurology & Neurosurgery, McGill University, Montreal, Quebec, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2017.06.027DOI Listing
November 2017

Application of calibrated fMRI in Alzheimer's disease.

Neuroimage Clin 2017 16;15:348-358. Epub 2017 May 16.

Département de Pharmacologie et physiologie, Université de Montréal, Montreal, QC, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Montreal Neurological Institute, Montreal, QC, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2017.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443910PMC
March 2018

Brain perfusion during rapid-eye-movement sleep successfully identifies amnestic mild cognitive impairment.

Sleep Med 2017 Jun 30;34:134-140. Epub 2017 Mar 30.

Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Canada; Faculty of Medicine, Université de Montréal, Montréal, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.sleep.2017.01.025DOI Listing
June 2017

Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.

Neurology 2017 May 12;88(19):1814-1821. Epub 2017 Apr 12.

From the Translational Neuroimaging Laboratory (K.P.N., T.A.P., S.M., C.-O.C., A.L.B., M.S., M.S.K., P.R.-N.) and Alzheimer's Disease Research Unit (K.P.N., X.L., M.B., P.R.-N., S.G.), McGill University Research Centre for Studies in Aging, Montreal, Quebec, Canada; Department of Neurology (K.P.N., N.K.), National Neuroscience Institute, Singapore; Montreal Neurological Institute (P.R.-N.); Department of Neurology and Neurosurgery (P.R.-N.), McGill University, Montreal, Quebec, Canada; Department of Neurology (X.L.), The Second Affiliated Hospital of Chongqing Medical University, Chongqing; and Department of Neurology (M.B.), Yantai Yuhuangding Hospital Affiliated to Qingdao Medical University, Shandong, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000003916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419982PMC
May 2017

Monoamine oxidase B inhibitor, selegiline, reduces F-THK5351 uptake in the human brain.

Alzheimers Res Ther 2017 Mar 31;9(1):25. Epub 2017 Mar 31.

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, 6825 LaSalle Boulevard, Verdun, Québec, H4H 1R3, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13195-017-0253-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374697PMC
March 2017

Recollection and familiarity in aging individuals: Gaining insight into relationships with medial temporal lobe structural integrity.

Hippocampus 2017 06 10;27(6):692-701. Epub 2017 Apr 10.

McGill University Research Center for Studies in Aging, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hipo.22725DOI Listing
June 2017

Consensus-based recommendations for the management of rapid cognitive decline due to Alzheimer's disease.

Alzheimers Dement 2017 May 24;13(5):592-597. Epub 2017 Feb 24.

Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2017.01.007DOI Listing
May 2017

Multicenter Validation of an MMSE-MoCA Conversion Table.

J Am Geriatr Soc 2017 May 15;65(5):1067-1072. Epub 2017 Feb 15.

Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques du CHU de Québec, and Faculté de Médecine, Université Laval, Québec, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgs.14779DOI Listing
May 2017

[F]FDG PET signal is driven by astroglial glutamate transport.

Nat Neurosci 2017 Mar 30;20(3):393-395. Epub 2017 Jan 30.

Translational Neuroimaging Laboratory (TNL), McGill Center for Studies in Aging (MCSA), Douglas Mental Health University Institute, Departments of Neurology and Neurosurgery, Psychiatry, and Pharmacology, McGill University, Montreal, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nn.4492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378483PMC
March 2017

Synergistic interaction between amyloid and tau predicts the progression to dementia.

Alzheimers Dement 2017 Jun 23;13(6):644-653. Epub 2016 Dec 23.

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Montreal, Canada; Montreal Neurological Institute, Montreal, Canada; AD Research Unit, The McGill University Research Centre for Studies in Aging, Montreal, Canada; McGill University, Montreal, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2016.11.005DOI Listing
June 2017

Research update on Alzheimer's disease and introduction to the Expert Review of Neurotherapeutics special issue.

Authors:
Serge Gauthier

Expert Rev Neurother 2017 01;17(1):1-2

a McGill Center for Studies in Aging , Montreal , Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14737175.2017.1268054DOI Listing
January 2017

Is ApoE ɛ 4 a good biomarker for amyloid pathology in late onset Alzheimer's disease?

Transl Neurodegener 2016 16;5:20. Epub 2016 Nov 16.

McGill Centre for Studies in Aging, McGill University, Douglas Institute, 6825 Lasalle Boul, Montreal, QC H4H 1R3 Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40035-016-0067-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112745PMC
November 2016

VoxelStats: A MATLAB Package for Multi-Modal Voxel-Wise Brain Image Analysis.

Front Neuroinform 2016 15;10:20. Epub 2016 Jun 15.

Translational Neuroimaging Laboratory, Departments of Neurology and Neurosurgery, McGill University Research Centre for Studies in Aging, Douglas Research Institute, McGill UniversityMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill UniversityMontreal, QC, Canada; McGill University Research Centre for Studies in Aging, Douglas Research Institute, McGill UniversityMontreal, QC, Canada; Douglas Hospital Research Center, Douglas Research Institute, McGill UniversityMontreal, QC, Canada; Department of Psychiatry, McGill UniversityMontreal, QC, Canada; Department of Neurology and Neurosurgery, McGill UniversityMontreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fninf.2016.00020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908129PMC
July 2016

Selective familiarity deficits in otherwise cognitively intact aging individuals with genetic risk for Alzheimer's disease.

Alzheimers Dement (Amst) 2016 23;2:132-9. Epub 2015 Dec 23.

McGill Centre for Studies in Aging, McGill University, Montreal, QC, Canada; Douglas Hospital Research Centre, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dadm.2015.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879663PMC
May 2016

Imaging Alzheimer's disease pathophysiology with PET.

Dement Neuropsychol 2016 Apr-Jun;10(2):79-90

Translational Neuroimaging Laboratory (TNL), McGill Center for Studies in Aging (MCSA), Douglas Mental Health Research Institute, Montreal, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/S1980-5764-2016DN1002003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642398PMC
December 2017

Hippocampus and amygdala volumes from magnetic resonance images in children: Assessing accuracy of FreeSurfer and FSL against manual segmentation.

Neuroimage 2016 Apr 26;129:1-14. Epub 2016 Jan 26.

McGill Centre for Studies in Aging, McGill University, Montreal, QC, Canada; Douglas Hospital Research Centre, Psychiatry Department, McGill University, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2016.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243960PMC
April 2016