Serena J Silver

Serena J Silver

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Serena J Silver

Serena J Silver

Publications by authors named "Serena J Silver"

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24Publications

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Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening.

J Vis Exp 2018 09 5(139). Epub 2018 Sep 5.

Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research.

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http://dx.doi.org/10.3791/57476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235107PMC
September 2018

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening.

Cell 2017 Jul;170(3):577-592.e10

Novartis Institutes for Biomedical Research, Oncology Disease Area, Basel 4002, Switzerland; Cambridge, MA 02139, USA; and Emeryville, CA 94608, USA.

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http://dx.doi.org/10.1016/j.cell.2017.07.005DOI Listing
July 2017

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.

Nat Genet 2014 Apr 2;46(4):364-70. Epub 2014 Mar 2.

1] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3] Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.

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http://www.nature.com/articles/ng.2913
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http://dx.doi.org/10.1038/ng.2913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086945PMC
April 2014

ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state.

Cell Rep 2014 Jan 16;6(2):313-24. Epub 2014 Jan 16.

Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.12.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041390PMC
January 2014

Functional screening identifies miR-315 as a potent activator of Wingless signaling.

Proc Natl Acad Sci U S A 2007 Nov 7;104(46):18151-6. Epub 2007 Nov 7.

Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0706673104
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http://dx.doi.org/10.1073/pnas.0706673104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2084312PMC
November 2007

Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays.

Nat Methods 2006 Oct;3(10):833-8

Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nmeth935DOI Listing
October 2006

New vision from Eyes absent: transcription factors as enzymes.

Trends Genet 2005 Mar;21(3):163-71

Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/j.tig.2005.01.005DOI Listing
March 2005

Signaling circuitries in development: insights from the retinal determination gene network.

Development 2005 Jan;132(1):3-13

Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1242/dev.01539DOI Listing
January 2005

New class of Son-of-sevenless (Sos) alleles highlights the complexities of Sos function.

Genesis 2004 Aug;39(4):263-72

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1002/gene.20054DOI Listing
August 2004

The transcription factor Eyes absent is a protein tyrosine phosphatase.

Nature 2003 Nov;426(6964):299-302

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature02097DOI Listing
November 2003

Functional dissection of eyes absent reveals new modes of regulation within the retinal determination gene network.

Mol Cell Biol 2003 Sep;23(17):5989-99

Whitehead Institute for Biomedical Research. MIT Department of Biology, Cambridge, Massachusetts 02142, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC180989PMC
http://dx.doi.org/10.1128/mcb.23.17.5989-5999.2003DOI Listing
September 2003