Publications by authors named "Sepideh Sadat Mirahmadi"

2 Publications

  • Page 1 of 1

Evaluation of dioxin-like polychlorinated biphenyls in fish of the Caspian Sea.

MethodsX 2020 23;7:100803. Epub 2020 Jan 23.

Non-Communicable Diseases Research Center, Department of Environmental Health, School of Public Health, Sabzevar University of Medical Sciences & Health Services, Sabzevar, Iran.

Dioxin-like polychlorinated biphenyls (DL-PCBs) have toxic properties for humans. The innovation of this study was that for the first time in Iran, 12 DL-PCBs concentration in 5 fish species: , , , and , from 5 coastal areas of the Caspian Sea (125 samples), were investigated. DL-PCBs extraction was in accordance to USEPA method 1668 revision A and carry out by chromatography columns modified with silica gel. DL-PCBs concentration were measured by HRGC (Agilent 6890 Series, Agilent Technologies, USA) coupled with HRMS AutoSpec Ultima NT-HRGC/HRMS (Micromass, USA), equipped with the HP-5MS 30 m × 0.25 mm × 0.25 μm column (Agilent Technologies) and helium as carrier gas. The mean concentration of DL-PCBs in samples ranged 232 ± 16-1156 ± 14 pg/g fat, that was in accordance with the Joint FAO/WHO Expert Committee on Food Additives and European Standards. The highest concentration was in of Bandar Anzali, and lowest obtained in samples from Chalous. However, based on fish consuming and fish originating from the fishing area the health risk evaluation to estimate the potential consequences of chronic exposure to DL-PCBs for consumers is recommended and effective measure for health risk reduction.
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http://dx.doi.org/10.1016/j.mex.2020.100803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000796PMC
January 2020

Comparing dioxin-like polychlorinated biphenyls in most consumed fish species of the Caspian Sea.

Environ Res 2020 01 1;180:108878. Epub 2019 Nov 1.

Non-Communicable Diseases Research Center, Department of Environmental Health, School of Public Health, Sabzevar University of Medical Sciences & Health Services, Sabzevar, Iran. Electronic address:

Among polychlorinated biphenyls (PCBs), dioxin-like PCBs (DL-PCBs) are of the most concern for human health. In this study, the levels of 12 DL-PCBs congeners were measured in 125 fish samples of the Caspian Sea, Iran. Five fish species (Oncorhynchus mykiss, Vimba vimba, Cyprinus carpio, Rutilus frisii kutum and Chelon saliens) were collected from 5 coastal cities of the Caspian Sea (25 samples per each city). Duncan's multi-scope test was used to compare the mean of DL-PCBs in different fish species and different cities. Probabilistic risk of exposure to DL-PCBs and sensitivity analysis were assessed using Monte Carlo simulation approach. The average (standard deviation) of DL-PCBs in fish samples ranged from 232 (16) to 1156 (14) pg/g lipids. The total maximum concentration was detected in Cyprinus carpio from Bandar Anzali, the minimum in Vimba vimba from Chalos. In all samples, non-carcinogenic risk of exposure to DL-PCBs was in safe level (Hazard Quotient < 1). In contrast, the lifetime cancer risk estimated for Bandar Anzali, Bandar Torkaman, and Rasht exceeded the threshold value of 1 × 10 suggested by United States Environmental Protection Agency. Sensitivity analysis indicated that the concentration of DL-PCBs and exposure frequency were the most effective parameters in increasing carcinogenic risk.
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http://dx.doi.org/10.1016/j.envres.2019.108878DOI Listing
January 2020