Publications by authors named "Seon-Jin Lee"

79Publications

Loss of desmoglein-2 promotes gallbladder carcinoma progression and resistance to EGFR-targeted therapy through Src kinase activation.

Cell Death Differ 2020 Sep 28. Epub 2020 Sep 28.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-020-00628-4DOI Listing
September 2020

Bacterial type III effector protein HopQ inhibits melanoma motility through autophagic degradation of vimentin.

Cell Death Dis 2020 04 14;11(4):231. Epub 2020 Apr 14.

Environmental Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41419-020-2427-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156461PMC
April 2020

Nucleotide-binding oligomerization domain protein 2 deficiency enhances CHOP expression and plaque necrosis in advanced atherosclerotic lesions.

FEBS J 2020 May 30;287(10):2055-2069. Epub 2020 Mar 30.

Laboratory of Molecular Immunology, Department of Biological Sciences, University of Ulsan, South Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/febs.15294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318642PMC
May 2020

Erastin Inhibits Septic Shock and Inflammatory Gene Expression via Suppression of the NF-κB Pathway.

J Clin Med 2019 Dec 14;8(12). Epub 2019 Dec 14.

Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong-gu, Daejeon 34141, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm8122210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947339PMC
December 2019

Preparation and Effect of (3-aminopropyl)triethoxysilane-Coated LiNiCoMnO₂ Cathode Material for Lithium Ion Batteries.

J Nanosci Nanotechnol 2020 Jun;20(6):3460-3465

Department of Materials Science and Engineering, Korea National University of Transportation, Chungju 27469, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1166/jnn.2020.17406DOI Listing
June 2020

Nucleotide-binding oligomerization domain protein 2 attenuates ER stress-induced cell death in vascular smooth muscle cells.

BMB Rep 2019 Nov;52(11):665-670

School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889894PMC
November 2019

Dynamic Interactions between Autophagosomes and Lipid Droplets in .

Cells 2019 08 28;8(9). Epub 2019 Aug 28.

Cell Factory Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cells8090992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769876PMC
August 2019

Effect of PEDOT:PSS (Poly(3,4-ethylenedioxythiophene)-polystyrenesulfonate) Coating on Nanostructured Cobalt-Free LiNiMnO₂ Layered Oxide Cathode Materials for Lithium-Ion Battery.

J Nanosci Nanotechnol 2020 Jan;20(1):338-343

Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju 27469, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1166/jnn.2020.17296DOI Listing
January 2020

Novel Composition of Co-Free LiNiMnAlO₂ Cathode Materials.

J Nanosci Nanotechnol 2020 Jan;20(1):190-196

Department of Nano-Polymer Science & Engineering, Korea National University of Transportation, Chungju, Chungbuk 27469, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1166/jnn.2020.17297DOI Listing
January 2020

G protein-coupled estrogen receptor-1 agonist induces chemotherapeutic effect via ER stress signaling in gastric cancer.

BMB Rep 2019 Nov;52(11):647-652

Immunotherapy Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889890PMC
November 2019

Epsilon-Globin HBE1 Enhances Radiotherapy Resistance by Down-Regulating BCL11A in Colorectal Cancer Cells.

Cancers (Basel) 2019 Apr 8;11(4). Epub 2019 Apr 8.

Immunotherapy Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers11040498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521047PMC
April 2019

Two distinct cellular pathways leading to endothelial cell cytotoxicity by silica nanoparticle size.

J Nanobiotechnology 2019 Feb 5;17(1):24. Epub 2019 Feb 5.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12951-019-0456-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362579PMC
February 2019

Angiotensin II Attenuates the Bioactivities of Human Endothelial Progenitor Cells via Downregulation of 2-Adrenergic Receptor.

Stem Cells Int 2018 29;2018:7453161. Epub 2018 Oct 29.

Department of Physiology, Laboratory for Vascular Medicine and Stem Cell Biology, Convergence Stem Cell Research Center, Medical Research Institute, Pusan National University School of Medicine, Yangsan 50612, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/7453161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231359PMC
October 2018

A Pilot Prospective Study of Refractory Solid Tumor Patients for NGS-Based Targeted Anticancer Therapy.

Transl Oncol 2019 Feb 16;12(2):301-307. Epub 2018 Nov 16.

BioMedical Research Institute, Pusan National University Hospital, 1-10 Ami-Dong, Seo-Gu, Busan 602-739, Republic of Korea; Department of Pathology, Pusan National University Hospital and Pusan National University School of Medicine, 179, Gudeok-ro, Seo-gu, Busan 49241, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S19365233183029
Publisher Site
http://dx.doi.org/10.1016/j.tranon.2018.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240710PMC
February 2019

Small heterodimer partner negatively regulates C-X-C motif chemokine ligand 2 in hepatocytes during liver inflammation.

Sci Rep 2018 10 15;8(1):15222. Epub 2018 Oct 15.

Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon, 34141, South Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-33660-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189097PMC
October 2018

Novel natural killer cell-mediated cancer immunotherapeutic activity of anisomycin against hepatocellular carcinoma cells.

Sci Rep 2018 Jul 13;8(1):10668. Epub 2018 Jul 13.

Bio & Drug Discovery Division, Center for Drug Discovery Technology, Korea Research Institute of Chemical Technology (KRICT), Daejeon, 305-600, Republic of Korea.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41598-018-29048-8
Publisher Site
http://dx.doi.org/10.1038/s41598-018-29048-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045618PMC
July 2018

Integrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer.

Br J Cancer 2018 07 29;119(2):230-240. Epub 2018 Jun 29.

Department of Pathology, Pusan National University School of Medicine, and Biomedical Research Institute, Pusan National University Hospital, Gudeok-ro 179, Seo-Gu, Busan, 49241, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41416-018-0153-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048111PMC
July 2018

The Ancient Phosphatidylinositol 3-Kinase Signaling System Is a Master Regulator of Energy and Carbon Metabolism in Algae.

Plant Physiol 2018 07 16;177(3):1050-1065. Epub 2018 May 16.

Cell Factory Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Yuseong-gu, Daejeon 34141, Republic of Korea

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1104/pp.17.01780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053016PMC
July 2018

Vitexin confers HSF-1 mediated autophagic cell death by activating JNK and ApoL1 in colorectal carcinoma cells.

Oncotarget 2017 Dec 10;8(68):112426-112441. Epub 2017 Aug 10.

Department of Biotechnology, Daegu University, Kyoungsan, Kyoungbook, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.20113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762521PMC
December 2017

Protein phosphatase 1B dephosphorylates Rho guanine nucleotide dissociation inhibitor 1 and suppresses cancer cell migration and invasion.

Cancer Lett 2018 03 5;417:141-151. Epub 2018 Jan 5.

Immunotherapy Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science and Technology (UST), Daejeon, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2018.01.002DOI Listing
March 2018

Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer.

Tumour Biol 2017 Oct;39(10):1010428317733985

1 Immunotherapy Convergence Research Group, Korea Research Institute of Bioscience & Biotechnology, Daejeon, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1010428317733985DOI Listing
October 2017

TWIST mediates resistance to paclitaxel by regulating Akt and Bcl-2 expression in gastric cancer cells.

Tumour Biol 2017 Oct;39(10):1010428317722070

Department of Pathology, Pusan National University School of Medicine and BioMedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1010428317722070DOI Listing
October 2017

Trichostatin A Sensitizes Hepatocellular Carcinoma Cells to Enhanced NK Cell-mediated Killing by Regulating Immune-related Genes.

Cancer Genomics Proteomics 2017 Sep-Oct;14(5):349-362

Immunotherapy Convergence Research Center, Korea Research Institute of Bioscience & Biotechnology (KRIBB), Daejeon, Republic of Korea

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21873/cgp.20045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611521PMC
May 2018

Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer.

Cell Death Dis 2017 03 16;8(3):e2682. Epub 2017 Mar 16.

Immunotherapy Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/cddis.2017.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386512PMC
March 2017

Graphene oxide induces apoptotic cell death in endothelial cells by activating autophagy via calcium-dependent phosphorylation of c-Jun N-terminal kinases.

Acta Biomater 2016 12 15;46:191-203. Epub 2016 Sep 15.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.actbio.2016.09.018DOI Listing
December 2016

Tescalcin expression contributes to invasive and metastatic activity in colorectal cancer.

Tumour Biol 2016 Oct 2;37(10):13843-13853. Epub 2016 Aug 2.

Genome Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 305-806, South Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13277-016-5262-0DOI Listing
October 2016

CCN1 suppresses pulmonary vascular smooth muscle contraction in response to hypoxia.

Pulm Circ 2015 Dec;5(4):716-22

Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1086/683812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671746PMC
December 2015

Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death.

Oncotarget 2015 Sep;6(27):24393-403

School of Biological Sciences, College of Natural Sciences, University of Ulsan, Ulsan 680-749, South Korea.

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/5162
Publisher Site
http://dx.doi.org/10.18632/oncotarget.5162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695193PMC
September 2015

Loss of NDRG2 promotes epithelial-mesenchymal transition of gallbladder carcinoma cells through MMP-19-mediated Slug expression.

J Hepatol 2015 Dec 17;63(6):1429-39. Epub 2015 Aug 17.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2015.08.007DOI Listing
December 2015

Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody.

Biomaterials 2015 May 17;51:119-128. Epub 2015 Feb 17.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biomaterials.2015.01.062DOI Listing
May 2015

Oleuropein prevents angiotensin II-mediated: Human vascular progenitor cell depletion.

Int J Cardiol 2015 Feb 25;181:160-5. Epub 2014 Nov 25.

Convergence Stem Cell Research Center, Department of Physiology, Pusan National University School of Medicine, South Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2014.11.174DOI Listing
February 2015

Mitochondrial dysfunction induces formation of lipid droplets as a generalized response to stress.

Oxid Med Cell Longev 2013 22;2013:327167. Epub 2013 Sep 22.

Biomedical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2013/327167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794647PMC
May 2014

TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis.

PLoS Pathog 2013 3;9(10):e1003646. Epub 2013 Oct 3.

Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong-gu, Daejeon, Republic of Korea ; Department of Functional Genomics, University of Science and Technology, Yuseong-gu, Daejeon, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1003646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789754PMC
May 2014

Caspase-mediated cleavage and DNase activity of the translation initiation factor 3, subunit G (eIF3g).

FEBS Lett 2013 Nov 27;587(22):3668-74. Epub 2013 Sep 27.

Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.febslet.2013.09.027DOI Listing
November 2013

Carbon monoxide confers protection in sepsis by enhancing beclin 1-dependent autophagy and phagocytosis.

Antioxid Redox Signal 2014 Jan 5;20(3):432-42. Epub 2013 Oct 5.

1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital , Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/ars.2013.5368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894711PMC
January 2014

p62 sequestosome 1/light chain 3b complex confers cytoprotection on lung epithelial cells after hyperoxia.

Am J Respir Cell Mol Biol 2013 Apr;48(4):489-96

Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://www.atsjournals.org/doi/abs/10.1165/rcmb.2012-0017OC
Publisher Site
http://dx.doi.org/10.1165/rcmb.2012-0017OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653608PMC
April 2013

NDRG2 and PRA1 interact and synergistically inhibit T-cell factor/β-catenin signaling.

FEBS Lett 2012 Nov 12;586(22):3962-8. Epub 2012 Oct 12.

Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.febslet.2012.09.045DOI Listing
November 2012

Overexpression and clinical significance of carcinoembryonic antigen-related cell adhesion molecule 6 in colorectal cancer.

Clin Chim Acta 2013 Jan 10;415:12-9. Epub 2012 Sep 10.

Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cca.2012.09.003DOI Listing
January 2013

Upregulation and secretion of kallikrein-related peptidase 6 (KLK6) in gastric cancer.

Tumour Biol 2012 Jun 29;33(3):731-8. Epub 2012 Feb 29.

Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806, Republic of Korea.

View Article

Download full-text PDF

Source
http://link.springer.com/content/pdf/10.1007/s13277-011-0267
Web Search
http://link.springer.com/10.1007/s13277-011-0267-1
Publisher Site
http://dx.doi.org/10.1007/s13277-011-0267-1DOI Listing
June 2012

Autophagy promotes intracellular degradation of type I collagen induced by transforming growth factor (TGF)-β1.

J Biol Chem 2012 Apr 20;287(15):11677-88. Epub 2012 Feb 20.

Renal Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M111.308460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320917PMC
April 2012

Carbon monoxide inhibits Fas activating antibody-induced apoptosis in endothelial cells.

Med Gas Res 2011 May 18;1(1). Epub 2011 May 18.

Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/2045-9912-1-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231877PMC
May 2011

Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death.

Am J Respir Cell Mol Biol 2012 Apr 17;46(4):507-14. Epub 2011 Nov 17.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2009-0415OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359946PMC
April 2012

Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis.

Autophagy 2011 Aug 1;7(8):829-39. Epub 2011 Aug 1.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149693PMC
http://dx.doi.org/10.4161/auto.7.8.15598DOI Listing
August 2011

Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation.

Am J Respir Cell Mol Biol 2011 Oct 25;45(4):867-73. Epub 2011 Mar 25.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://www.atsjournals.org/doi/abs/10.1165/rcmb.2010-0352OC
Publisher Site
http://dx.doi.org/10.1165/rcmb.2010-0352OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208612PMC
October 2011

Transforming growth factor-β1 suppression of endotoxin-induced heme oxygenase-1 in macrophages involves activation of Smad2 and downregulation of Ets-2.

J Cell Physiol 2012 Jan;227(1):351-60

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jcp.22741
Publisher Site
http://dx.doi.org/10.1002/jcp.22741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132305PMC
January 2012

Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis.

Free Radic Biol Med 2011 May 5;50(10):1252-62. Epub 2011 Mar 5.

Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2011.02.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134776PMC
May 2011

Caveolin-1: a critical regulator of lung injury.

Am J Physiol Lung Cell Mol Physiol 2011 Feb 19;300(2):L151-60. Epub 2010 Nov 19.

Division of Pulmonary and Critical Care Medicine, Dept. of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00170.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380484PMC
February 2011

Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema.

Proc Natl Acad Sci U S A 2010 Nov 18;107(44):18880-5. Epub 2010 Oct 18.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1005574107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973911PMC
November 2010

Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease.

Expert Rev Respir Med 2010 Oct;4(5):573-84

Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/ers.10.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081520PMC
October 2010

TGF-{beta}1 protects against mesangial cell apoptosis via induction of autophagy.

J Biol Chem 2010 Nov 28;285(48):37909-19. Epub 2010 Sep 28.

Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.093724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988393PMC
November 2010

Autophagy in vascular disease.

Proc Am Thorac Soc 2010 Feb;7(1):40-7

Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1513/pats.200909-100JSDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137148PMC
February 2010

Deletion of caveolin-1 protects hyperoxia-induced apoptosis via survivin-mediated pathways.

Am J Physiol Lung Cell Mol Physiol 2009 Nov 18;297(5):L945-53. Epub 2009 Sep 18.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, MUH 628NW, 3459 5th Ave., Pittsburgh, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00081.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777493PMC
November 2009

Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1.

Autophagy 2008 Oct 12;4(7):887-95. Epub 2008 Oct 12.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, MUH 628NW, Pittsburgh, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/auto.6767DOI Listing
October 2008

CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation.

Biochem Pharmacol 2008 Jul 18;76(1):79-90. Epub 2008 Apr 18.

Department of Molecular and Cellular Biochemistry and Vascular System Research Center, School of Medicine, Kangwon National University, Chunchon, Kangwon-Do 200-701, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2008.04.006DOI Listing
July 2008

Protein kinase C alpha and zeta differentially regulate death-inducing signaling complex formation in cigarette smoke extract-induced apoptosis.

J Immunol 2008 Apr;180(7):4668-78

Department of Pulmonary and Critical Care Medicine, Gachon Medical School, Gil Medical Center, Inchon, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.180.7.4668DOI Listing
April 2008

Colchicine-derived compound CT20126 promotes skin allograft survival by regulating the balance of Th1 and Th2 cytokine production.

Exp Mol Med 2007 Apr;39(2):230-8

Vascular System Research Center, School of Medicine, Kangwon National University, Chuncheon 200-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/emm.2007.26DOI Listing
April 2007

Fractalkine stimulates angiogenesis by activating the Raf-1/MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways.

Am J Physiol Heart Circ Physiol 2006 Dec 28;291(6):H2836-46. Epub 2006 Jul 28.

Dept. of Molecular and Cellular Biochemistry, Kangwon National University, Chunchon, Kangwon-do 200-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.00113.2006DOI Listing
December 2006

Prostaglandin E2 stimulates angiogenesis by activating the nitric oxide/cGMP pathway in human umbilical vein endothelial cells.

Exp Mol Med 2005 Dec;37(6):588-600

Vascular System Research Center, School of Medicine, Kangwon National University, Chuncheon 200-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/emm.2005.72DOI Listing
December 2005

beta-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macrophages by suppressing redox-based NF-kappaB activation.

Exp Mol Med 2005 Aug;37(4):323-34

Vascular System Research Center, Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chunchon, Kangwon-do 200-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/emm.2005.42DOI Listing
August 2005

Amiloride potentiates TRAIL-induced tumor cell apoptosis by intracellular acidification-dependent Akt inactivation.

Biochem Biophys Res Commun 2005 Jan;326(4):752-8

Vascular System Research Center, Kangwon National University, Chunchon, Kangwon-do, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2004.11.109DOI Listing
January 2005

Nitric oxide inhibition of homocysteine-induced human endothelial cell apoptosis by down-regulation of p53-dependent Noxa expression through the formation of S-nitrosohomocysteine.

J Biol Chem 2005 Feb 23;280(7):5781-8. Epub 2004 Nov 23.

Vascular System Research Center and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chunchon, Kangwon-do 200-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M411224200DOI Listing
February 2005

Nitric oxide suppresses inducible nitric oxide synthase expression by inhibiting post-translational modification of IkappaB.

Exp Mol Med 2004 Aug;36(4):311-24

Department of Molecular and Cellular Biochemistry, School of Medicine Kangwon National University, Chuncheon, Gangwon-do, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/emm.2004.42DOI Listing
August 2004

Inhibition of farnesyltransferase prevents collagen-induced arthritis by down-regulation of inflammatory gene expression through suppression of p21(ras)-dependent NF-kappaB activation.

J Immunol 2004 Jul;173(2):1276-83

Vascular System Research Center and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chunchon, Kangwon-do, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.173.2.1276DOI Listing
July 2004

Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation.

Mol Cells 2003 Aug;16(1):97-105

Vascular System Research Center and Department of Molecular and Cellular Biochemistry, Kangwon National University Biology, Chunchon 200-701, Korea.

View Article

Download full-text PDF

Source
http://www.cyanotech.com/pdfs/bioastin/batl03.pdf
Web Search
August 2003

Nitric oxide (NO) pretreatment increases cytokine-induced NO production in cultured rat hepatocytes by suppressing GTP cyclohydrolase I feedback inhibitory protein level and promoting inducible NO synthase dimerization.

J Biol Chem 2002 Dec 30;277(49):47073-9. Epub 2002 Sep 30.

Vascular System Research Center and Department of Molecular and Cellular Biochemistry, Kangwon National University, School of Medicine, Chunchon, Kangwon-do 200-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M207053200DOI Listing
December 2002