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Publications Authored by Senthilmurugan Ramalingam | PubFacts
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The retinamide VNLG-152 inhibits f-AR/AR-V7 and MNK-eIF4E signaling pathways to suppress EMT and castration-resistant prostate cancer xenograft growth.

FEBS J 2018 03 3;285(6):1051-1063. Epub 2018 Feb 3.

Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1111/febs.14383DOI Listing
March 2018

Targeting of protein translation as a new treatment paradigm for prostate cancer.

Curr Opin Oncol 2017 Mar 9. Epub 2017 Mar 9.

aDepartment of Pharmacology bCenter for Biomolecular Therapeutics cMarlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine dVeterans Affairs Medical Center, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/CCO.0000000000000367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591782PMC
March 2017

Dissecting major signaling pathways in prostate cancer development and progression: Mechanisms and novel therapeutic targets.

J Steroid Biochem Mol Biol 2017 02 30;166:16-27. Epub 2016 Jul 30.

Department of Pharmacology, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201-1559, USA; Center for Biomolecular Therapeutics, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201-1559, USA; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201-1559, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2016.07.006DOI Listing
February 2017

Identification of Novel Steroidal Androgen Receptor Degrading Agents Inspired by Galeterone 3β-Imidazole Carbamate.

ACS Med Chem Lett 2016 Jul 23;7(7):708-13. Epub 2016 May 23.

Department of Pharmacology, Center for Biomolecular Therapeutics, and Marlene Stewart Greenbaum Cancer Center, University of Maryland School of Medicine , 685 West Baltimore Street, Baltimore, Maryland 21201-1559, United States.

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http://dx.doi.org/10.1021/acsmedchemlett.6b00137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948004PMC
July 2016

Novel C-4 heteroaryl 13-cis-retinamide Mnk/AR degrading agents inhibit cell proliferation and migration and induce apoptosis in human breast and prostate cancer cells and suppress growth of MDA-MB-231 human breast and CWR22Rv1 human prostate tumor xenografts in mice.

J Med Chem 2015 Feb 12;58(4):1900-14. Epub 2015 Feb 12.

Department of Pharmacology, ‡Center for Biomolecular Therapeutics, and §Marlene Stewart Greenebaum Cancer Center, University of Maryland School of Medicine , 685 West Baltimore Street, Baltimore, Maryland 21201-1559, United States.

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http://pubs.acs.org/doi/10.1021/jm501792c
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http://dx.doi.org/10.1021/jm501792cDOI Listing
February 2015

VN/14-1 induces ER stress and autophagy in HP-LTLC human breast cancer cells and has excellent oral pharmacokinetic profile in female Sprague Dawley rats.

Eur J Pharmacol 2014 Jul 12;734:98-104. Epub 2014 Apr 12.

Department of Pharmacology, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201-1559, USA; Center for Biomolecular Therapeutics, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201-1559, USA; Marlene Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201-1559, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2014.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047216PMC
July 2014