Senno Verhoef

Senno Verhoef

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Senno Verhoef

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Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.

Genet Med 2017 05 6;19(5):599-603. Epub 2016 Oct 6.

Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/gim.2016.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382131PMC
May 2017

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.

Authors:
Melissa C Southey David E Goldgar Robert Winqvist Katri Pylkäs Fergus Couch Marc Tischkowitz William D Foulkes Joe Dennis Kyriaki Michailidou Elizabeth J van Rensburg Tuomas Heikkinen Heli Nevanlinna John L Hopper Thilo Dörk Kathleen Bm Claes Jorge Reis-Filho Zhi Ling Teo Paolo Radice Irene Catucci Paolo Peterlongo Helen Tsimiklis Fabrice A Odefrey James G Dowty Marjanka K Schmidt Annegien Broeks Frans B Hogervorst Senno Verhoef Jane Carpenter Christine Clarke Rodney J Scott Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Julian Peto Isabel Dos-Santos-Silva Olivia Fletcher Nichola Johnson Manjeet K Bolla Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Federik Marme Barbara Burwinkel Rongxi Yang Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Stig Bojesen Sune F Nielsen Henrik Flyger Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Hoda Anton-Culver Susan Neuhausen Argyrios Ziogas Christina A Clarke Hermann Brenner Volker Arndt Christa Stegmaier Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Taru A Muranen Kristiina Aittomäki Carl Blomqvist Natalia V Bogdanova Natalia N Antonenkova Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Amanda B Spurdle kConFab Investigators Els Wauters Dominiek Smeets Benoit Beuselinck Giuseppe Floris Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Janet E Olson Celine Vachon Vernon S Pankratz Catriona McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Vessela Kristensen Grethe Grenaker Alnæs Wei Zheng David J Hunter Sara Lindstrom Susan E Hankinson Peter Kraft Irene Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Arja Jukkola-Vuorinen Mervi Grip Saila Kauppila Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Antoinette Hollestelle Montserrat Garcia-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Hatef Darabi Mikael Eriksson Diana M Eccles Sajjad Rafiq William J Tapper Sue M Gerty Maartje J Hooning John W M Martens J Margriet Collée Madeleine Tilanus-Linthorst Per Hall Jingmei Li Judith S Brand Keith Humphreys Angela Cox Malcolm W R Reed Craig Luccarini Caroline Baynes Alison M Dunning Ute Hamann Diana Torres Hans Ulrich Ulmer Thomas Rüdiger Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Anthony Swerdlow Alan Ashworth Nick Orr Michael Jones Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Jacques Simard Martine Dumont Penny Soucy Rosalind Eeles Kenneth Muir Fredrik Wiklund Henrik Gronberg Johanna Schleutker Børge G Nordestgaard Maren Weischer Ruth C Travis David Neal Jenny L Donovan Freddie C Hamdy Kay-Tee Khaw Janet L Stanford William J Blot Stephen Thibodeau Daniel J Schaid Joseph L Kelley Christiane Maier Adam S Kibel Cezary Cybulski Lisa Cannon-Albright Katja Butterbach Jong Park Radka Kaneva Jyotsna Batra Manuel R Teixeira Zsofia Kote-Jarai Ali Amin Al Olama Sara Benlloch Stefan P Renner Arndt Hartmann Alexander Hein Matthias Ruebner Diether Lambrechts Els Van Nieuwenhuysen Ignace Vergote Sandrina Lambretchs Jennifer A Doherty Mary Anne Rossing Stefan Nickels Ursula Eilber Shan Wang-Gohrke Kunle Odunsi Lara E Sucheston-Campbell Grace Friel Galina Lurie Jeffrey L Killeen Lynne R Wilkens Marc T Goodman Ingo Runnebaum Peter A Hillemanns Liisa M Pelttari Ralf Butzow Francesmary Modugno Robert P Edwards Roberta B Ness Kirsten B Moysich Andreas du Bois Florian Heitz Philipp Harter Stefan Kommoss Beth Y Karlan Christine Walsh Jenny Lester Allan Jensen Susanne Krüger Kjaer Estrid Høgdall Bernard Peissel Bernardo Bonanni Loris Bernard Ellen L Goode Brooke L Fridley Robert A Vierkant Julie M Cunningham Melissa C Larson Zachary C Fogarty Kimberly R Kalli Dong Liang Karen H Lu Michelle A T Hildebrandt Xifeng Wu Douglas A Levine Fanny Dao Maria Bisogna Andrew Berchuck Edwin S Iversen Jeffrey R Marks Lucy Akushevich Daniel W Cramer Joellen Schildkraut Kathryn L Terry Elizabeth M Poole Meir Stampfer Shelley S Tworoger Elisa V Bandera Irene Orlow Sara H Olson Line Bjorge Helga B Salvesen Anne M van Altena Katja K H Aben Lambertus A Kiemeney Leon F A G Massuger Tanja Pejovic Yukie Bean Angela Brooks-Wilson Linda E Kelemen Linda S Cook Nhu D Le Bohdan Górski Jacek Gronwald Janusz Menkiszak Claus K Høgdall Lene Lundvall Lotte Nedergaard Svend Aage Engelholm Ed Dicks Jonathan Tyrer Ian Campbell Iain McNeish James Paul Nadeem Siddiqui Rosalind Glasspool Alice S Whittemore Joseph H Rothstein Valerie McGuire Weiva Sieh Hui Cai Xiao-Ou Shu Rachel T Teten Rebecca Sutphen John R McLaughlin Steven A Narod Catherine M Phelan Alvaro N Monteiro David Fenstermacher Hui-Yi Lin Jennifer B Permuth Thomas A Sellers Y Ann Chen Ya-Yu Tsai Zhihua Chen Aleksandra Gentry-Maharaj Simon A Gayther Susan J Ramus Usha Menon Anna H Wu Celeste L Pearce David Van Den Berg Malcolm C Pike Agnieszka Dansonka-Mieszkowska Joanna Plisiecka-Halasa Joanna Moes-Sosnowska Jolanta Kupryjanczyk Paul Dp Pharoah Honglin Song Ingrid Winship Georgia Chenevix-Trench Graham G Giles Sean V Tavtigian Doug F Easton Roger L Milne

J Med Genet 2016 12 5;53(12):800-811. Epub 2016 Sep 5.

Centre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1136/jmedgenet-2016-103839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200636PMC
December 2016

Do BRCA1/2 mutation carriers have an earlier onset of natural menopause?

Menopause 2016 08;23(8):903-10

1Department of Reproductive Medicine 2Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands 3Department of Epidemiology 4Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, The Netherlands 5Department of Genetics, Groningen University, University Medical Center, Groningen, The Netherlands 6Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands 7GROW, School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands 8Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands 9Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands 10Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands 11Department of Obstetrics and Gynaecology, Division of Gynaecology Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands 12Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/GME.0000000000000633DOI Listing
August 2016

Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.

Authors:
Yan Guo Shaneda Warren Andersen Xiao-Ou Shu Kyriaki Michailidou Manjeet K Bolla Qin Wang Montserrat Garcia-Closas Roger L Milne Marjanka K Schmidt Jenny Chang-Claude Allison Dunning Stig E Bojesen Habibul Ahsan Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Volker Arndt Matthias W Beckmann Alicia Beeghly-Fadiel Javier Benitez Natalia V Bogdanova Bernardo Bonanni Anne-Lise Børresen-Dale Judith Brand Hiltrud Brauch Hermann Brenner Thomas Brüning Barbara Burwinkel Graham Casey Georgia Chenevix-Trench Fergus J Couch Angela Cox Simon S Cross Kamila Czene Peter Devilee Thilo Dörk Martine Dumont Peter A Fasching Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger Florentia Fostira Marilie Gammon Graham G Giles Pascal Guénel Christopher A Haiman Ute Hamann Maartje J Hooning John L Hopper Anna Jakubowska Farzana Jasmine Mark Jenkins Esther M John Nichola Johnson Michael E Jones Maria Kabisch Muhammad Kibriya Julia A Knight Linetta B Koppert Veli-Matti Kosma Vessela Kristensen Loic Le Marchand Eunjung Lee Jingmei Li Annika Lindblom Robert Luben Jan Lubinski Kathi E Malone Arto Mannermaa Sara Margolin Frederik Marme Catriona McLean Hanne Meijers-Heijboer Alfons Meindl Susan L Neuhausen Heli Nevanlinna Patrick Neven Janet E Olson Jose I A Perez Barbara Perkins Paolo Peterlongo Kelly-Anne Phillips Katri Pylkäs Anja Rudolph Regina Santella Elinor J Sawyer Rita K Schmutzler Caroline Seynaeve Mitul Shah Martha J Shrubsole Melissa C Southey Anthony J Swerdlow Amanda E Toland Ian Tomlinson Diana Torres Thérèse Truong Giske Ursin Rob B Van Der Luijt Senno Verhoef Alice S Whittemore Robert Winqvist Hui Zhao Shilin Zhao Per Hall Jacques Simard Peter Kraft Paul Pharoah David Hunter Douglas F Easton Wei Zheng

PLoS Med 2016 08 23;13(8):e1002105. Epub 2016 Aug 23.

Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995025PMC
August 2016

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.

Authors:
Chenjie Zeng Xingyi Guo Jirong Long Karoline B Kuchenbaecker Arnaud Droit Kyriaki Michailidou Maya Ghoussaini Siddhartha Kar Adam Freeman John L Hopper Roger L Milne Manjeet K Bolla Qin Wang Joe Dennis Simona Agata Shahana Ahmed Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Adalgeir Arason Volker Arndt Banu K Arun Brita Arver Francois Bacot Daniel Barrowdale Caroline Baynes Alicia Beeghly-Fadiel Javier Benitez Marina Bermisheva Carl Blomqvist William J Blot Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Borresen-Dale Judith S Brand Hiltrud Brauch Paul Brennan Hermann Brenner Annegien Broeks Thomas Brüning Barbara Burwinkel Saundra S Buys Qiuyin Cai Trinidad Caldes Ian Campbell Jane Carpenter Jenny Chang-Claude Ji-Yeob Choi Kathleen B M Claes Christine Clarke Angela Cox Simon S Cross Kamila Czene Mary B Daly Miguel de la Hoya Kim De Leeneer Peter Devilee Orland Diez Susan M Domchek Michele Doody Cecilia M Dorfling Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Miriam Dwek Bernd Dworniczak Kathleen Egan Ursula Eilber Zakaria Einbeigi Bent Ejlertsen Steve Ellis Debra Frost Fiona Lalloo Peter A Fasching Jonine Figueroa Henrik Flyger Michael Friedlander Eitan Friedman Gaetana Gambino Yu-Tang Gao Judy Garber Montserrat García-Closas Andrea Gehrig Francesca Damiola Fabienne Lesueur Sylvie Mazoyer Dominique Stoppa-Lyonnet Graham G Giles Andrew K Godwin David E Goldgar Anna González-Neira Mark H Greene Pascal Guénel Lothar Haeberle Christopher A Haiman Emily Hallberg Ute Hamann Thomas V O Hansen Steven Hart Jaana M Hartikainen Mikael Hartman Norhashimah Hassan Sue Healey Frans B L Hogervorst Senno Verhoef Carolyn B Hendricks Peter Hillemanns Antoinette Hollestelle Peter J Hulick David J Hunter Evgeny N Imyanitov Claudine Isaacs Hidemi Ito Anna Jakubowska Ramunas Janavicius Katarzyna Jaworska-Bieniek Uffe Birk Jensen Esther M John Charles Joly Beauparlant Michael Jones Maria Kabisch Daehee Kang Beth Y Karlan Saila Kauppila Michael J Kerin Sofia Khan Elza Khusnutdinova Julia A Knight Irene Konstantopoulou Peter Kraft Ava Kwong Yael Laitman Diether Lambrechts Conxi Lazaro Loic Le Marchand Chuen Neng Lee Min Hyuk Lee Jenny Lester Jingmei Li Annelie Liljegren Annika Lindblom Artitaya Lophatananon Jan Lubinski Phuong L Mai Arto Mannermaa Siranoush Manoukian Sara Margolin Frederik Marme Keitaro Matsuo Lesley McGuffog Alfons Meindl Florence Menegaux Marco Montagna Kenneth Muir Anna Marie Mulligan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Silje Nord Robert L Nussbaum Kenneth Offit Edith Olah Olufunmilayo I Olopade Curtis Olswold Ana Osorio Laura Papi Tjoung-Won Park-Simon Ylva Paulsson-Karlsson Stephanie Peeters Bernard Peissel Paolo Peterlongo Julian Peto Georg Pfeiler Catherine M Phelan Nadege Presneau Paolo Radice Nazneen Rahman Susan J Ramus Muhammad Usman Rashid Gad Rennert Kerstin Rhiem Anja Rudolph Ritu Salani Suleeporn Sangrajrang Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Minouk J Schoemaker Peter Schürmann Caroline Seynaeve Chen-Yang Shen Martha J Shrubsole Xiao-Ou Shu Alice Sigurdson Christian F Singer Susan Slager Penny Soucy Melissa Southey Doris Steinemann Anthony Swerdlow Csilla I Szabo Sandrine Tchatchou Manuel R Teixeira Soo H Teo Mary Beth Terry Daniel C Tessier Alex Teulé Mads Thomassen Laima Tihomirova Marc Tischkowitz Amanda E Toland Nadine Tung Clare Turnbull Ans M W van den Ouweland Elizabeth J van Rensburg David Ven den Berg Joseph Vijai Shan Wang-Gohrke Jeffrey N Weitzel Alice S Whittemore Robert Winqvist Tien Y Wong Anna H Wu Drakoulis Yannoukakos Jyh-Cherng Yu Paul D P Pharoah Per Hall Georgia Chenevix-Trench Alison M Dunning Jacques Simard Fergus J Couch Antonis C Antoniou Douglas F Easton Wei Zheng

Breast Cancer Res 2016 06 21;18(1):64. Epub 2016 Jun 21.

Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, 2525 West End Avenue, 8th Floor, Nashville, TN, 37203-1738, USA.

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http://dx.doi.org/10.1186/s13058-016-0718-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962376PMC
June 2016

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

Authors:
Antoinette Hollestelle Frederieke H van der Baan Andrew Berchuck Sharon E Johnatty Katja K Aben Bjarni A Agnarsson Kristiina Aittomäki Elisa Alducci Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Antonis C Antoniou Carmel Apicella Volker Arndt Norbert Arnold Banu K Arun Brita Arver Alan Ashworth Laura Baglietto Rosemary Balleine Elisa V Bandera Daniel Barrowdale Yukie T Bean Lars Beckmann Matthias W Beckmann Javier Benitez Andreas Berger Raanan Berger Benoit Beuselinck Maria Bisogna Line Bjorge Carl Blomqvist Natalia V Bogdanova Anders Bojesen Stig E Bojesen Manjeet K Bolla Bernardo Bonanni Judith S Brand Hiltrud Brauch Hermann Brenner Louise Brinton Angela Brooks-Wilson Fiona Bruinsma Joan Brunet Thomas Brüning Agnieszka Budzilowska Clareann H Bunker Barbara Burwinkel Ralf Butzow Saundra S Buys Maria A Caligo Ian Campbell Jonathan Carter Jenny Chang-Claude Stephen J Chanock Kathleen B M Claes J Margriet Collée Linda S Cook Fergus J Couch Angela Cox Daniel Cramer Simon S Cross Julie M Cunningham Cezary Cybulski Kamila Czene Francesca Damiola Agnieszka Dansonka-Mieszkowska Hatef Darabi Miguel de la Hoya Anna deFazio Joseph Dennis Peter Devilee Ed M Dicks Orland Diez Jennifer A Doherty Susan M Domchek Cecilia M Dorfling Thilo Dörk Isabel Dos Santos Silva Andreas du Bois Martine Dumont Alison M Dunning Mercedes Duran Douglas F Easton Diana Eccles Robert P Edwards Hans Ehrencrona Bent Ejlertsen Arif B Ekici Steve D Ellis Christoph Engel Mikael Eriksson Peter A Fasching Lidia Feliubadalo Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Annette Fontaine Stefano Fortuzzi Florentia Fostira Brooke L Fridley Tara Friebel Eitan Friedman Grace Friel Debra Frost Judy Garber Montserrat García-Closas Simon A Gayther Aleksandra Gentry-Maharaj Anne-Marie Gerdes Graham G Giles Rosalind Glasspool Gord Glendon Andrew K Godwin Marc T Goodman Martin Gore Mark H Greene Mervi Grip Jacek Gronwald Daphne Gschwantler Kaulich Pascal Guénel Starr R Guzman Lothar Haeberle Christopher A Haiman Per Hall Sandra L Halverson Ute Hamann Thomas V O Hansen Philipp Harter Jaana M Hartikainen Sue Healey Alexander Hein Florian Heitz Brian E Henderson Josef Herzog Michelle A T Hildebrandt Claus K Høgdall Estrid Høgdall Frans B L Hogervorst John L Hopper Keith Humphreys Tomasz Huzarski Evgeny N Imyanitov Claudine Isaacs Anna Jakubowska Ramunas Janavicius Katarzyna Jaworska Allan Jensen Uffe Birk Jensen Nichola Johnson Arja Jukkola-Vuorinen Maria Kabisch Beth Y Karlan Vesa Kataja Noah Kauff Linda E Kelemen Michael J Kerin Lambertus A Kiemeney Susanne K Kjaer Julia A Knight Jacoba P Knol-Bout Irene Konstantopoulou Veli-Matti Kosma Camilla Krakstad Vessela Kristensen Karoline B Kuchenbaecker Jolanta Kupryjanczyk Yael Laitman Diether Lambrechts Sandrina Lambrechts Melissa C Larson Adriana Lasa Pierre Laurent-Puig Conxi Lazaro Nhu D Le Loic Le Marchand Arto Leminen Jenny Lester Douglas A Levine Jingmei Li Dong Liang Annika Lindblom Noralane Lindor Jolanta Lissowska Jirong Long Karen H Lu Jan Lubinski Lene Lundvall Galina Lurie Phuong L Mai Arto Mannermaa Sara Margolin Frederique Mariette Frederik Marme John W M Martens Leon F A G Massuger Christine Maugard Sylvie Mazoyer Lesley McGuffog Valerie McGuire Catriona McLean Iain McNeish Alfons Meindl Florence Menegaux Primitiva Menéndez Janusz Menkiszak Usha Menon Arjen R Mensenkamp Nicola Miller Roger L Milne Francesmary Modugno Marco Montagna Kirsten B Moysich Heiko Müller Anna Marie Mulligan Taru A Muranen Steven A Narod Katherine L Nathanson Roberta B Ness Susan L Neuhausen Heli Nevanlinna Patrick Neven Finn C Nielsen Sune F Nielsen Børge G Nordestgaard Robert L Nussbaum Kunle Odunsi Kenneth Offit Edith Olah Olufunmilayo I Olopade Janet E Olson Sara H Olson Jan C Oosterwijk Irene Orlow Nick Orr Sandra Orsulic Ana Osorio Laura Ottini James Paul Celeste L Pearce Inge Sokilde Pedersen Bernard Peissel Tanja Pejovic Liisa M Pelttari Jo Perkins Jenny Permuth-Wey Paolo Peterlongo Julian Peto Catherine M Phelan Kelly-Anne Phillips Marion Piedmonte Malcolm C Pike Radka Platte Joanna Plisiecka-Halasa Elizabeth M Poole Bruce Poppe Katri Pylkäs Paolo Radice Susan J Ramus Timothy R Rebbeck Malcolm W R Reed Gad Rennert Harvey A Risch Mark Robson Gustavo C Rodriguez Atocha Romero Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo Runnebaum Ritu Salani Helga B Salvesen Elinor J Sawyer Joellen M Schildkraut Marjanka K Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Michael G Schrauder Fredrick Schumacher Ira Schwaab Giulietta Scuvera Thomas A Sellers Gianluca Severi Caroline M Seynaeve Mitul Shah Martha Shrubsole Nadeem Siddiqui Weiva Sieh Jacques Simard Christian F Singer Olga M Sinilnikova Dominiek Smeets Christof Sohn Maria Soller Honglin Song Penny Soucy Melissa C Southey Christa Stegmaier Dominique Stoppa-Lyonnet Lara Sucheston Anthony Swerdlow Ingvild L Tangen Muy-Kheng Tea Manuel R Teixeira Kathryn L Terry Mary Beth Terry Mads Thomassen Pamela J Thompson Laima Tihomirova Marc Tischkowitz Amanda Ewart Toland Rob A E M Tollenaar Ian Tomlinson Diana Torres Thérèse Truong Helen Tsimiklis Nadine Tung Shelley S Tworoger Jonathan P Tyrer Celine M Vachon Laura J Van 't Veer Anne M van Altena C J Van Asperen David van den Berg Ans M W van den Ouweland Helena C van Doorn Els Van Nieuwenhuysen Elizabeth J van Rensburg Ignace Vergote Senno Verhoef Robert A Vierkant Joseph Vijai Allison F Vitonis Anna von Wachenfeldt Christine Walsh Qin Wang Shan Wang-Gohrke Barbara Wappenschmidt Maren Weischer Jeffrey N Weitzel Caroline Weltens Nicolas Wentzensen Alice S Whittemore Lynne R Wilkens Robert Winqvist Anna H Wu Xifeng Wu Hannah P Yang Daniela Zaffaroni M Pilar Zamora Wei Zheng Argyrios Ziogas Georgia Chenevix-Trench Paul D P Pharoah Matti A Rookus Maartje J Hooning Ellen L Goode

Gynecol Oncol 2016 05 2;141(2):386-401. Epub 2015 May 2.

Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.ygyno.2015.04.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630206PMC
May 2016

No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing.

Authors:
Douglas F Easton Fabienne Lesueur Brennan Decker Kyriaki Michailidou Jun Li Jamie Allen Craig Luccarini Karen A Pooley Mitul Shah Manjeet K Bolla Qin Wang Joe Dennis Jamil Ahmad Ella R Thompson Francesca Damiola Maroulio Pertesi Catherine Voegele Noura Mebirouk Nivonirina Robinot Geoffroy Durand Nathalie Forey Robert N Luben Shahana Ahmed Kristiina Aittomäki Hoda Anton-Culver Volker Arndt Caroline Baynes Matthias W Beckman Javier Benitez David Van Den Berg William J Blot Natalia V Bogdanova Stig E Bojesen Hermann Brenner Jenny Chang-Claude Kee Seng Chia Ji-Yeob Choi Don M Conroy Angela Cox Simon S Cross Kamila Czene Hatef Darabi Peter Devilee Mikael Eriksson Peter A Fasching Jonine Figueroa Henrik Flyger Florentia Fostira Montserrat García-Closas Graham G Giles Gord Glendon Anna González-Neira Pascal Guénel Christopher A Haiman Per Hall Steven N Hart Mikael Hartman Maartje J Hooning Chia-Ni Hsiung Hidemi Ito Anna Jakubowska Paul A James Esther M John Nichola Johnson Michael Jones Maria Kabisch Daehee Kang Veli-Matti Kosma Vessela Kristensen Diether Lambrechts Na Li Annika Lindblom Jirong Long Artitaya Lophatananon Jan Lubinski Arto Mannermaa Siranoush Manoukian Sara Margolin Keitaro Matsuo Alfons Meindl Gillian Mitchell Kenneth Muir Ines Nevelsteen Ans van den Ouweland Paolo Peterlongo Sze Yee Phuah Katri Pylkäs Simone M Rowley Suleeporn Sangrajrang Rita K Schmutzler Chen-Yang Shen Xiao-Ou Shu Melissa C Southey Harald Surowy Anthony Swerdlow Soo H Teo Rob A E M Tollenaar Ian Tomlinson Diana Torres Thérèse Truong Celine Vachon Senno Verhoef Michelle Wong-Brown Wei Zheng Ying Zheng Heli Nevanlinna Rodney J Scott Irene L Andrulis Anna H Wu John L Hopper Fergus J Couch Robert Winqvist Barbara Burwinkel Elinor J Sawyer Marjanka K Schmidt Anja Rudolph Thilo Dörk Hiltrud Brauch Ute Hamann Susan L Neuhausen Roger L Milne Olivia Fletcher Paul D P Pharoah Ian G Campbell Alison M Dunning Florence Le Calvez-Kelm David E Goldgar Sean V Tavtigian Georgia Chenevix-Trench

J Med Genet 2016 05 26;53(5):298-309. Epub 2016 Feb 26.

Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.

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http://dx.doi.org/10.1136/jmedgenet-2015-103529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938802PMC
May 2016

Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry.

Authors:
Zhiguo Zhao Wanqing Wen Kyriaki Michailidou Manjeet K Bolla Qin Wang Ben Zhang Jirong Long Xiao-Ou Shu Marjanka K Schmidt Roger L Milne Montserrat García-Closas Jenny Chang-Claude Sara Lindstrom Stig E Bojesen Habibul Ahsan Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Volker Arndt Matthias W Beckmann Alicia Beeghly-Fadiel Javier Benitez Carl Blomqvist Natalia V Bogdanova Anne-Lise Børresen-Dale Judith Brand Hiltrud Brauch Hermann Brenner Barbara Burwinkel Qiuyin Cai Graham Casey Georgia Chenevix-Trench Fergus J Couch Angela Cox Simon S Cross Kamila Czene Thilo Dörk Martine Dumont Peter A Fasching Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger Florentia Fostira Marilie Gammon Graham G Giles Pascal Guénel Christopher A Haiman Ute Hamann Patricia Harrington Mikael Hartman Maartje J Hooning John L Hopper Anna Jakubowska Farzana Jasmine Esther M John Nichola Johnson Maria Kabisch Sofia Khan Muhammad Kibriya Julia A Knight Veli-Matti Kosma Mieke Kriege Vessela Kristensen Loic Le Marchand Eunjung Lee Jingmei Li Annika Lindblom Artitaya Lophatananon Robert Luben Jan Lubinski Kathleen E Malone Arto Mannermaa Siranoush Manoukian Sara Margolin Frederik Marme Catriona McLean Hanne Meijers-Heijboer Alfons Meindl Hui Miao Kenneth Muir Susan L Neuhausen Heli Nevanlinna Patrick Neven Janet E Olson Barbara Perkins Paolo Peterlongo Kelly-Anne Phillips Katri Pylkäs Anja Rudolph Regina Santella Elinor J Sawyer Rita K Schmutzler Minouk Schoemaker Mitul Shah Martha Shrubsole Melissa C Southey Anthony J Swerdlow Amanda E Toland Ian Tomlinson Diana Torres Thérèse Truong Giske Ursin Rob B Van Der Luijt Senno Verhoef Shan Wang-Gohrke Alice S Whittemore Robert Winqvist M Pilar Zamora Hui Zhao Alison M Dunning Jacques Simard Per Hall Peter Kraft Paul Pharoah David Hunter Douglas F Easton Wei Zheng

Cancer Causes Control 2016 May 6;27(5):679-93. Epub 2016 Apr 6.

Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, 2525 West End Avenue, 8th Floor, Nashville, TN, 37203-1738, USA.

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http://dx.doi.org/10.1007/s10552-016-0741-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029371PMC
May 2016

Oligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated MSH2 DNA mismatch repair gene variants.

Proc Natl Acad Sci U S A 2016 Apr 7;113(15):4128-33. Epub 2016 Mar 7.

Division of Biological Stress Response, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1520813113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839441PMC
April 2016

Evaluation of the Dutch BRCA1/2 clinical genetic center referral criteria in an unselected early breast cancer population.

Eur J Hum Genet 2015 May 20;23(5):588-95. Epub 2014 Aug 20.

1] Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands [2] Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1038/ejhg.2014.161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402636PMC
May 2015

Prediction of breast cancer risk based on profiling with common genetic variants.

Authors:
Nasim Mavaddat Paul D P Pharoah Kyriaki Michailidou Jonathan Tyrer Mark N Brook Manjeet K Bolla Qin Wang Joe Dennis Alison M Dunning Mitul Shah Robert Luben Judith Brown Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Kamila Czene Hatef Darabi Mikael Eriksson Julian Peto Isabel Dos-Santos-Silva Frank Dudbridge Nichola Johnson Marjanka K Schmidt Annegien Broeks Senno Verhoef Emiel J Rutgers Anthony Swerdlow Alan Ashworth Nick Orr Minouk J Schoemaker Jonine Figueroa Stephen J Chanock Louise Brinton Jolanta Lissowska Fergus J Couch Janet E Olson Celine Vachon Vernon S Pankratz Diether Lambrechts Hans Wildiers Chantal Van Ongeval Erik van Limbergen Vessela Kristensen Grethe Grenaker Alnæs Silje Nord Anne-Lise Borresen-Dale Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Amy Trentham-Dietz Polly Newcomb Linda Titus Kathleen M Egan David J Hunter Sara Lindstrom Rulla M Tamimi Peter Kraft Nazneen Rahman Clare Turnbull Anthony Renwick Sheila Seal Jingmei Li Jianjun Liu Keith Humphreys Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Natalia V Bogdanova Natalia N Antonenkova Thilo Dörk Hoda Anton-Culver Susan L Neuhausen Argyrios Ziogas Leslie Bernstein Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J van Asperen Angela Cox Simon S Cross Malcolm W R Reed Elza Khusnutdinova Marina Bermisheva Darya Prokofyeva Zalina Takhirova Alfons Meindl Rita K Schmutzler Christian Sutter Rongxi Yang Peter Schürmann Michael Bremer Hans Christiansen Tjoung-Won Park-Simon Peter Hillemanns Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Paolo Radice Paolo Peterlongo Siranoush Manoukian Valeria Pensotti John L Hopper Helen Tsimiklis Carmel Apicella Melissa C Southey Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Alice J Sigurdson Michele M Doody Ute Hamann Diana Torres Hans-Ulrich Ulmer Asta Försti Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Georgia Chenevix-Trench Rosemary Balleine Graham G Giles Roger L Milne Catriona McLean Annika Lindblom Sara Margolin Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Ursula Eilber Shan Wang-Gohrke Maartje J Hooning Antoinette Hollestelle Ans M W van den Ouweland Linetta B Koppert Jane Carpenter Christine Clarke Rodney Scott Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Hermann Brenner Volker Arndt Christa Stegmaier Aida Karina Dieffenbach Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Kenneth Offit Joseph Vijai Mark Robson Rohini Rau-Murthy Miriam Dwek Ruth Swann Katherine Annie Perkins Mark S Goldberg France Labrèche Martine Dumont Diana M Eccles William J Tapper Sajjad Rafiq Esther M John Alice S Whittemore Susan Slager Drakoulis Yannoukakos Amanda E Toland Song Yao Wei Zheng Sandra L Halverson Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Jacques Simard Per Hall Douglas F Easton Montserrat Garcia-Closas

J Natl Cancer Inst 2015 May 8;107(5). Epub 2015 Apr 8.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK (NM, PDPP, KM, MKB, QW, JD, RL, JBr, DFE); Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK (PDPP, JT, AMD, MS, CL, CB, SA, MM, CSH, DFE); Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK (MNB, ASw, MJS); Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark (SEB, BGN, SFN); Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (SEB, BGN, SFN); Faculty of Health and Medical Sciences, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (SEB, BGN); Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (HF); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (KC, HD, ME, KH, PHa); Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK (JP, IdSS, FD); Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK (NJ, AA, NO, MGC); Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands (MKS, AB, SV, EJR); Division of Breast Cancer Research, Institute of Cancer Research, London, UK (ASw); Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD (JF, SJC, LB, ASi, MD); Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland (JLis); Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN (FJC); Department of Health Sciences Research, Mayo Clinic, Rochester, MN (JEO, CV, VSP, SS); Vesalius Research Center, VIB, Leuven, Belgium (DL); Laboratory for Translational Genetics, Department of Oncology, University of

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754625PMC
May 2015

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.

Authors:
Kyriaki Michailidou Jonathan Beesley Sara Lindstrom Sander Canisius Joe Dennis Michael J Lush Mel J Maranian Manjeet K Bolla Qin Wang Mitul Shah Barbara J Perkins Kamila Czene Mikael Eriksson Hatef Darabi Judith S Brand Stig E Bojesen Børge G Nordestgaard Henrik Flyger Sune F Nielsen Nazneen Rahman Clare Turnbull Olivia Fletcher Julian Peto Lorna Gibson Isabel dos-Santos-Silva Jenny Chang-Claude Dieter Flesch-Janys Anja Rudolph Ursula Eilber Sabine Behrens Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Sofia Khan Kirsimari Aaltonen Habibul Ahsan Muhammad G Kibriya Alice S Whittemore Esther M John Kathleen E Malone Marilie D Gammon Regina M Santella Giske Ursin Enes Makalic Daniel F Schmidt Graham Casey David J Hunter Susan M Gapstur Mia M Gaudet W Ryan Diver Christopher A Haiman Fredrick Schumacher Brian E Henderson Loic Le Marchand Christine D Berg Stephen J Chanock Jonine Figueroa Robert N Hoover Diether Lambrechts Patrick Neven Hans Wildiers Erik van Limbergen Marjanka K Schmidt Annegien Broeks Senno Verhoef Sten Cornelissen Fergus J Couch Janet E Olson Emily Hallberg Celine Vachon Quinten Waisfisz Hanne Meijers-Heijboer Muriel A Adank Rob B van der Luijt Jingmei Li Jianjun Liu Keith Humphreys Daehee Kang Ji-Yeob Choi Sue K Park Keun-Young Yoo Keitaro Matsuo Hidemi Ito Hiroji Iwata Kazuo Tajima Pascal Guénel Thérèse Truong Claire Mulot Marie Sanchez Barbara Burwinkel Frederik Marme Harald Surowy Christof Sohn Anna H Wu Chiu-chen Tseng David Van Den Berg Daniel O Stram Anna González-Neira Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Annika Lindblom Sara Margolin Soo Hwang Teo Cheng Har Yip Nur Aishah Mohd Taib Gie-Hooi Tan Maartje J Hooning Antoinette Hollestelle John W M Martens J Margriet Collée William Blot Lisa B Signorello Qiuyin Cai John L Hopper Melissa C Southey Helen Tsimiklis Carmel Apicella Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Ming-Feng Hou Vessela N Kristensen Silje Nord Grethe I Grenaker Alnaes Graham G Giles Roger L Milne Catriona McLean Federico Canzian Dimitrios Trichopoulos Petra Peeters Eiliv Lund Malin Sund Kay-Tee Khaw Marc J Gunter Domenico Palli Lotte Maxild Mortensen Laure Dossus Jose-Maria Huerta Alfons Meindl Rita K Schmutzler Christian Sutter Rongxi Yang Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Mikael Hartman Hui Miao Kee Seng Chia Ching Wan Chan Peter A Fasching Alexander Hein Matthias W Beckmann Lothar Haeberle Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Alan Ashworth Nick Orr Minouk J Schoemaker Anthony J Swerdlow Louise Brinton Montserrat Garcia-Closas Wei Zheng Sandra L Halverson Martha Shrubsole Jirong Long Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Hiltrud Brauch Ute Hamann Thomas Brüning Paolo Radice Paolo Peterlongo Siranoush Manoukian Loris Bernard Natalia V Bogdanova Thilo Dörk Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska Tomasz Huzarski Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James McKay Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Maria Kabisch Diana Torres Susan L Neuhausen Hoda Anton-Culver Craig Luccarini Caroline Baynes Shahana Ahmed Catherine S Healey Daniel C Tessier Daniel Vincent Francois Bacot Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Jacques Simard Paul P D P Pharoah Peter Kraft Alison M Dunning Georgia Chenevix-Trench Per Hall Douglas F Easton

Nat Genet 2015 Apr 9;47(4):373-80. Epub 2015 Mar 9.

1] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [2] Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549775PMC
April 2015

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

Authors:
Timothy R Rebbeck Nandita Mitra Fei Wan Olga M Sinilnikova Sue Healey Lesley McGuffog Sylvie Mazoyer Georgia Chenevix-Trench Douglas F Easton Antonis C Antoniou Katherine L Nathanson Yael Laitman Anya Kushnir Shani Paluch-Shimon Raanan Berger Jamal Zidan Eitan Friedman Hans Ehrencrona Marie Stenmark-Askmalm Zakaria Einbeigi Niklas Loman Katja Harbst Johanna Rantala Beatrice Melin Dezheng Huo Olufunmilayo I Olopade Joyce Seldon Patricia A Ganz Robert L Nussbaum Salina B Chan Kunle Odunsi Simon A Gayther Susan M Domchek Banu K Arun Karen H Lu Gillian Mitchell Beth Y Karlan Christine Walsh Jenny Lester Andrew K Godwin Harsh Pathak Eric Ross Mary B Daly Alice S Whittemore Esther M John Alexander Miron Mary Beth Terry Wendy K Chung David E Goldgar Saundra S Buys Ramunas Janavicius Laima Tihomirova Nadine Tung Cecilia M Dorfling Elizabeth J van Rensburg Linda Steele Susan L Neuhausen Yuan Chun Ding Bent Ejlertsen Anne-Marie Gerdes Thomas v O Hansen Teresa Ramón y Cajal Ana Osorio Javier Benitez Javier Godino Maria-Isabel Tejada Mercedes Duran Jeffrey N Weitzel Kristie A Bobolis Sharon R Sand Annette Fontaine Antonella Savarese Barbara Pasini Bernard Peissel Bernardo Bonanni Daniela Zaffaroni Francesca Vignolo-Lutati Giulietta Scuvera Giuseppe Giannini Loris Bernard Maurizio Genuardi Paolo Radice Riccardo Dolcetti Siranoush Manoukian Valeria Pensotti Viviana Gismondi Drakoulis Yannoukakos Florentia Fostira Judy Garber Diana Torres Muhammad Usman Rashid Ute Hamann Susan Peock Debra Frost Radka Platte D Gareth Evans Rosalind Eeles Rosemarie Davidson Diana Eccles Trevor Cole Jackie Cook Carole Brewer Shirley Hodgson Patrick J Morrison Lisa Walker Mary E Porteous M John Kennedy Louise Izatt Julian Adlard Alan Donaldson Steve Ellis Priyanka Sharma Rita Katharina Schmutzler Barbara Wappenschmidt Alexandra Becker Kerstin Rhiem Eric Hahnen Christoph Engel Alfons Meindl Stefanie Engert Nina Ditsch Norbert Arnold Hans Jörg Plendl Christoph Mundhenke Dieter Niederacher Markus Fleisch Christian Sutter C R Bartram Nicola Dikow Shan Wang-Gohrke Dorothea Gadzicki Doris Steinemann Karin Kast Marit Beer Raymonda Varon-Mateeva Andrea Gehrig Bernhard H Weber Dominique Stoppa-Lyonnet Olga M Sinilnikova Sylvie Mazoyer Claude Houdayer Muriel Belotti Marion Gauthier-Villars Francesca Damiola Nadia Boutry-Kryza Christine Lasset Hagay Sobol Jean-Philippe Peyrat Danièle Muller Jean-Pierre Fricker Marie-Agnès Collonge-Rame Isabelle Mortemousque Catherine Nogues Etienne Rouleau Claudine Isaacs Anne De Paepe Bruce Poppe Kathleen Claes Kim De Leeneer Marion Piedmonte Gustavo Rodriguez Katie Wakely John Boggess Stephanie V Blank Jack Basil Masoud Azodi Kelly-Anne Phillips Trinidad Caldes Miguel de la Hoya Atocha Romero Heli Nevanlinna Kristiina Aittomäki Annemarie H van der Hout Frans B L Hogervorst Senno Verhoef J Margriet Collée Caroline Seynaeve Jan C Oosterwijk Johannes J P Gille Juul T Wijnen Encarna B Gómez Garcia Carolien M Kets Margreet G E M Ausems Cora M Aalfs Peter Devilee Arjen R Mensenkamp Ava Kwong Edith Olah Janos Papp Orland Diez Conxi Lazaro Esther Darder Ignacio Blanco Mónica Salinas Anna Jakubowska Jan Lubinski Jacek Gronwald Katarzyna Jaworska-Bieniek Katarzyna Durda Grzegorz Sukiennicki Tomasz Huzarski Tomasz Byrski Cezary Cybulski Aleksandra Toloczko-Grabarek Elżbieta Złowocka-Perłowska Janusz Menkiszak Adalgeir Arason Rosa B Barkardottir Jacques Simard Rachel Laframboise Marco Montagna Simona Agata Elisa Alducci Ana Peixoto Manuel R Teixeira Amanda B Spurdle Min Hyuk Lee Sue K Park Sung-Won Kim Tara M Friebel Fergus J Couch Noralane M Lindor Vernon S Pankratz Lucia Guidugli Xianshu Wang Marc Tischkowitz Lenka Foretova Joseph Vijai Kenneth Offit Mark Robson Rohini Rau-Murthy Noah Kauff Anneliese Fink-Retter Christian F Singer Christine Rappaport Daphne Gschwantler-Kaulich Georg Pfeiler Muy-Kheng Tea Andreas Berger Mark H Greene Phuong L Mai Evgeny N Imyanitov Amanda Ewart Toland Leigha Senter Anders Bojesen Inge Sokilde Pedersen Anne-Bine Skytte Lone Sunde Mads Thomassen Sanne Traasdahl Moeller Torben A Kruse Uffe Birk Jensen Maria Adelaide Caligo Paolo Aretini Soo-Hwang Teo Christina G Selkirk Peter J Hulick Irene Andrulis

JAMA 2015 Apr;313(13):1347-61

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada.

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April 2015

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia.

Authors:
Amanda B Spurdle Fergus J Couch Michael T Parsons Lesley McGuffog Daniel Barrowdale Manjeet K Bolla Qin Wang Sue Healey Rita Schmutzler Barbara Wappenschmidt Kerstin Rhiem Eric Hahnen Christoph Engel Alfons Meindl Nina Ditsch Norbert Arnold Hansjoerg Plendl Dieter Niederacher Christian Sutter Shan Wang-Gohrke Doris Steinemann Sabine Preisler-Adams Karin Kast Raymonda Varon-Mateeva Steve Ellis Debra Frost Radka Platte Jo Perkins D Gareth Evans Louise Izatt Ros Eeles Julian Adlard Rosemarie Davidson Trevor Cole Giulietta Scuvera Siranoush Manoukian Bernardo Bonanni Frederique Mariette Stefano Fortuzzi Alessandra Viel Barbara Pasini Laura Papi Liliana Varesco Rosemary Balleine Katherine L Nathanson Susan M Domchek Kenneth Offitt Anna Jakubowska Noralane Lindor Mads Thomassen Uffe Birk Jensen Johanna Rantala Åke Borg Irene L Andrulis Alexander Miron Thomas V O Hansen Trinidad Caldes Susan L Neuhausen Amanda E Toland Heli Nevanlinna Marco Montagna Judy Garber Andrew K Godwin Ana Osorio Rachel E Factor Mary B Terry Timothy R Rebbeck Beth Y Karlan Melissa Southey Muhammad Usman Rashid Nadine Tung Paul D P Pharoah Fiona M Blows Alison M Dunning Elena Provenzano Per Hall Kamila Czene Marjanka K Schmidt Annegien Broeks Sten Cornelissen Senno Verhoef Peter A Fasching Matthias W Beckmann Arif B Ekici Dennis J Slamon Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Jenny Chang-Claude Dieter Flesch-Janys Anja Rudolph Petra Seibold Kristiina Aittomäki Taru A Muranen Päivi Heikkilä Carl Blomqvist Jonine Figueroa Stephen J Chanock Louise Brinton Jolanta Lissowska Janet E Olson Vernon S Pankratz Esther M John Alice S Whittemore Dee W West Ute Hamann Diana Torres Hans Ulrich Ulmer Thomas Rüdiger Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Diana M Eccles William J Tapper Lorraine Durcan Louise Jones Julian Peto Isabel dos-Santos-Silva Olivia Fletcher Nichola Johnson Miriam Dwek Ruth Swann Anita L Bane Gord Glendon Anna M Mulligan Graham G Giles Roger L Milne Laura Baglietto Catriona McLean Jane Carpenter Christine Clarke Rodney Scott Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Angela Cox Simon S Cross Malcolm W R Reed Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Jacek Gronwald Thilo Dörk Natalia Bogdanova Tjoung-Won Park-Simon Peter Hillemanns Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Barbara Burwinkel Frederik Marme Harald Surovy Rongxi Yang Hoda Anton-Culver Argyrios Ziogas Maartje J Hooning J Margriet Collée John W M Martens Madeleine M A Tilanus-Linthorst Hermann Brenner Aida Karina Dieffenbach Volke Arndt Christa Stegmaier Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Annika Lindblom Sara Margolin Vijai Joseph Mark Robson Rohini Rau-Murthy Anna González-Neira José Ignacio Arias Pilar Zamora Javier Benítez Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Paolo Peterlongo Daniela Zaffaroni Monica Barile Fabio Capra Paolo Radice Soo H Teo Douglas F Easton Antonis C Antoniou Georgia Chenevix-Trench David E Goldgar

Breast Cancer Res 2014 Dec 23;16(6):3419. Epub 2014 Dec 23.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352262PMC
December 2014

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium.

Authors:
Roger L Milne Jesús Herranz Kyriaki Michailidou Joe Dennis Jonathan P Tyrer M Pilar Zamora José Ignacio Arias-Perez Anna González-Neira Guillermo Pita M Rosario Alonso Qin Wang Manjeet K Bolla Kamila Czene Mikael Eriksson Keith Humphreys Hatef Darabi Jingmei Li Hoda Anton-Culver Susan L Neuhausen Argyrios Ziogas Christina A Clarke John L Hopper Gillian S Dite Carmel Apicella Melissa C Southey Georgia Chenevix-Trench Anthony Swerdlow Alan Ashworth Nicholas Orr Minouk Schoemaker Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Stig E Bojesen Børge G Nordestgaard Henrik Flyger Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Xianshu Wang Janet E Olson Celine Vachon Kristen Purrington Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Alison M Dunning Mitul Shah Pascal Guénel Thérèse Truong Marie Sanchez Claire Mulot Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Annika Lindblom Sara Margolin Maartje J Hooning Antoinette Hollestelle J Margriet Collée Agnes Jager Angela Cox Ian W Brock Malcolm W R Reed Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Martine Dumont Penny Soucy Thilo Dörk Natalia V Bogdanova Ute Hamann Asta Försti Thomas Rüdiger Hans-Ulrich Ulmer Peter A Fasching Lothar Häberle Arif B Ekici Matthias W Beckmann Olivia Fletcher Nichola Johnson Isabel dos Santos Silva Julian Peto Paolo Radice Paolo Peterlongo Bernard Peissel Paolo Mariani Graham G Giles Gianluca Severi Laura Baglietto Elinor Sawyer Ian Tomlinson Michael Kerin Nicola Miller Federik Marme Barbara Burwinkel Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Diether Lambrechts Betul T Yesilyurt Giuseppe Floris Karin Leunen Grethe Grenaker Alnæs Vessela Kristensen Anne-Lise Børresen-Dale Montserrat García-Closas Stephen J Chanock Jolanta Lissowska Jonine D Figueroa Marjanka K Schmidt Annegien Broeks Senno Verhoef Emiel J Rutgers Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Fergus J Couch Amanda E Toland Drakoulis Yannoukakos Paul D P Pharoah Per Hall Javier Benítez Núria Malats Douglas F Easton

Hum Mol Genet 2014 Apr 15;23(7):1934-46. Epub 2013 Nov 15.

Human Cancer Genetics Programme and.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943524PMC
April 2014

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.

Authors:
Fergus J Couch Xianshu Wang Lesley McGuffog Andrew Lee Curtis Olswold Karoline B Kuchenbaecker Penny Soucy Zachary Fredericksen Daniel Barrowdale Joe Dennis Mia M Gaudet Ed Dicks Matthew Kosel Sue Healey Olga M Sinilnikova Adam Lee François Bacot Daniel Vincent Frans B L Hogervorst Susan Peock Dominique Stoppa-Lyonnet Anna Jakubowska Paolo Radice Rita Katharina Schmutzler Susan M Domchek Marion Piedmonte Christian F Singer Eitan Friedman Mads Thomassen Thomas V O Hansen Susan L Neuhausen Csilla I Szabo Ignacio Blanco Mark H Greene Beth Y Karlan Judy Garber Catherine M Phelan Jeffrey N Weitzel Marco Montagna Edith Olah Irene L Andrulis Andrew K Godwin Drakoulis Yannoukakos David E Goldgar Trinidad Caldes Heli Nevanlinna Ana Osorio Mary Beth Terry Mary B Daly Elizabeth J van Rensburg Ute Hamann Susan J Ramus Amanda Ewart Toland Maria A Caligo Olufunmilayo I Olopade Nadine Tung Kathleen Claes Mary S Beattie Melissa C Southey Evgeny N Imyanitov Marc Tischkowitz Ramunas Janavicius Esther M John Ava Kwong Orland Diez Judith Balmaña Rosa B Barkardottir Banu K Arun Gad Rennert Soo-Hwang Teo Patricia A Ganz Ian Campbell Annemarie H van der Hout Carolien H M van Deurzen Caroline Seynaeve Encarna B Gómez Garcia Flora E van Leeuwen Hanne E J Meijers-Heijboer Johannes J P Gille Margreet G E M Ausems Marinus J Blok Marjolijn J L Ligtenberg Matti A Rookus Peter Devilee Senno Verhoef Theo A M van Os Juul T Wijnen Debra Frost Steve Ellis Elena Fineberg Radka Platte D Gareth Evans Louise Izatt Rosalind A Eeles Julian Adlard Diana M Eccles Jackie Cook Carole Brewer Fiona Douglas Shirley Hodgson Patrick J Morrison Lucy E Side Alan Donaldson Catherine Houghton Mark T Rogers Huw Dorkins Jacqueline Eason Helen Gregory Emma McCann Alex Murray Alain Calender Agnès Hardouin Pascaline Berthet Capucine Delnatte Catherine Nogues Christine Lasset Claude Houdayer Dominique Leroux Etienne Rouleau Fabienne Prieur Francesca Damiola Hagay Sobol Isabelle Coupier Laurence Venat-Bouvet Laurent Castera Marion Gauthier-Villars Mélanie Léoné Pascal Pujol Sylvie Mazoyer Yves-Jean Bignon Elżbieta Złowocka-Perłowska Jacek Gronwald Jan Lubinski Katarzyna Durda Katarzyna Jaworska Tomasz Huzarski Amanda B Spurdle Alessandra Viel Bernard Peissel Bernardo Bonanni Giulia Melloni Laura Ottini Laura Papi Liliana Varesco Maria Grazia Tibiletti Paolo Peterlongo Sara Volorio Siranoush Manoukian Valeria Pensotti Norbert Arnold Christoph Engel Helmut Deissler Dorothea Gadzicki Andrea Gehrig Karin Kast Kerstin Rhiem Alfons Meindl Dieter Niederacher Nina Ditsch Hansjoerg Plendl Sabine Preisler-Adams Stefanie Engert Christian Sutter Raymonda Varon-Mateeva Barbara Wappenschmidt Bernhard H F Weber Brita Arver Marie Stenmark-Askmalm Niklas Loman Richard Rosenquist Zakaria Einbeigi Katherine L Nathanson Timothy R Rebbeck Stephanie V Blank David E Cohn Gustavo C Rodriguez Laurie Small Michael Friedlander Victoria L Bae-Jump Anneliese Fink-Retter Christine Rappaport Daphne Gschwantler-Kaulich Georg Pfeiler Muy-Kheng Tea Noralane M Lindor Bella Kaufman Shani Shimon Paluch Yael Laitman Anne-Bine Skytte Anne-Marie Gerdes Inge Sokilde Pedersen Sanne Traasdahl Moeller Torben A Kruse Uffe Birk Jensen Joseph Vijai Kara Sarrel Mark Robson Noah Kauff Anna Marie Mulligan Gord Glendon Hilmi Ozcelik Bent Ejlertsen Finn C Nielsen Lars Jønson Mette K Andersen Yuan Chun Ding Linda Steele Lenka Foretova Alex Teulé Conxi Lazaro Joan Brunet Miquel Angel Pujana Phuong L Mai Jennifer T Loud Christine Walsh Jenny Lester Sandra Orsulic Steven A Narod Josef Herzog Sharon R Sand Silvia Tognazzo Simona Agata Tibor Vaszko Joellen Weaver Alexandra V Stavropoulou Saundra S Buys Atocha Romero Miguel de la Hoya Kristiina Aittomäki Taru A Muranen Mercedes Duran Wendy K Chung Adriana Lasa Cecilia M Dorfling Alexander Miron Javier Benitez Leigha Senter Dezheng Huo Salina B Chan Anna P Sokolenko Jocelyne Chiquette Laima Tihomirova Tara M Friebel Bjarni A Agnarsson Karen H Lu Flavio Lejbkowicz Paul A James Per Hall Alison M Dunning Daniel Tessier Julie Cunningham Susan L Slager Chen Wang Steven Hart Kristen Stevens Jacques Simard Tomi Pastinen Vernon S Pankratz Kenneth Offit Douglas F Easton Georgia Chenevix-Trench Antonis C Antoniou

PLoS Genet 2013 27;9(3):e1003212. Epub 2013 Mar 27.

Department of Laboratory Medicine and Pathology, and Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609646PMC
June 2013

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.

Authors:
Juliet D French Maya Ghoussaini Stacey L Edwards Kerstin B Meyer Kyriaki Michailidou Shahana Ahmed Sofia Khan Mel J Maranian Martin O'Reilly Kristine M Hillman Joshua A Betts Thomas Carroll Peter J Bailey Ed Dicks Jonathan Beesley Jonathan Tyrer Ana-Teresa Maia Andrew Beck Nicholas W Knoblauch Constance Chen Peter Kraft Daniel Barnes Anna González-Neira M Rosario Alonso Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Craig Luccarini Caroline Baynes Don Conroy Joe Dennis Manjeet K Bolla Qin Wang John L Hopper Melissa C Southey Marjanka K Schmidt Annegien Broeks Senno Verhoef Sten Cornelissen Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Peter A Fasching Christian R Loehberg Arif B Ekici Matthias W Beckmann Julian Peto Isabel dos Santos Silva Nichola Johnson Zoe Aitken Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Frederik Marme Andreas Schneeweiss Christof Sohn Barbara Burwinkel Pascal Guénel Thérèse Truong Pierre Laurent-Puig Florence Menegaux Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Roger L Milne M Pilar Zamora Jose Ignacio Arias Perez Javier Benitez Hoda Anton-Culver Hermann Brenner Heiko Müller Volker Arndt Christa Stegmaier Alfons Meindl Peter Lichtner Rita K Schmutzler Christoph Engel Hiltrud Brauch Ute Hamann Christina Justenhoven Kirsimari Aaltonen Päivi Heikkilä Kristiina Aittomäki Carl Blomqvist Keitaro Matsuo Hidemi Ito Hiroji Iwata Aiko Sueta Natalia V Bogdanova Natalia N Antonenkova Thilo Dörk Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Anna H Wu Chiu-chen Tseng David Van Den Berg Daniel O Stram Diether Lambrechts Stephanie Peeters Ann Smeets Giuseppe Floris Jenny Chang-Claude Anja Rudolph Stefan Nickels Dieter Flesch-Janys Paolo Radice Paolo Peterlongo Bernardo Bonanni Domenico Sardella Fergus J Couch Xianshu Wang Vernon S Pankratz Adam Lee Graham G Giles Gianluca Severi Laura Baglietto Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Soo Hwang Teo Cheng Har Yip Char-Hong Ng Eranga Nishanthie Vithana Vessela Kristensen Wei Zheng Sandra Deming-Halverson Martha Shrubsole Jirong Long Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Peter Devilee Caroline Seynaeve Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Daniel Klevebring Nils Schoof Maartje J Hooning John W M Martens J Margriet Collée Madeleine Tilanus-Linthorst Per Hall Jingmei Li Jianjun Liu Keith Humphreys Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Angela Cox Sabapathy P Balasubramanian William Blot Lisa B Signorello Qiuyin Cai Paul D P Pharoah Catherine S Healey Mitul Shah Karen A Pooley Daehee Kang Keun-Young Yoo Dong-Young Noh Mikael Hartman Hui Miao Jen-Hwei Sng Xueling Sim Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Suleeporn Sangrajrang Valerie Gaborieau James McKay Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Andrew K Godwin Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Shou-Tung Chen Anthony Swerdlow Alan Ashworth Nick Orr Minouk J Schoemaker Bruce A J Ponder Heli Nevanlinna Melissa A Brown Georgia Chenevix-Trench Douglas F Easton Alison M Dunning

Am J Hum Genet 2013 Apr 27;92(4):489-503. Epub 2013 Mar 27.

School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1016/j.ajhg.2013.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617380PMC
April 2013

Breast cancer genetic counseling after diagnosis but before treatment: a pilot study on treatment consequences and psychological impact.

Patient Educ Couns 2012 Oct 28;89(1):89-95. Epub 2012 Apr 28.

Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.pec.2012.03.019DOI Listing
October 2012

Prediction of BRCA2-association in hereditary breast carcinomas using array-CGH.

Breast Cancer Res Treat 2012 Apr 8;132(2):379-89. Epub 2010 Jul 8.

Division of Experimental Therapy, The Netherlands Cancer Institute NKI/AvL, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-010-1016-7DOI Listing
April 2012

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers.

Authors:
Antonis C Antoniou Karoline B Kuchenbaecker Penny Soucy Jonathan Beesley Xiaoqing Chen Lesley McGuffog Andrew Lee Daniel Barrowdale Sue Healey Olga M Sinilnikova Maria A Caligo Niklas Loman Katja Harbst Annika Lindblom Brita Arver Richard Rosenquist Per Karlsson Kate Nathanson Susan Domchek Tim Rebbeck Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Elżbieta Złowowcka-Perłowska Ana Osorio Mercedes Durán Raquel Andrés Javier Benítez Ute Hamann Frans B Hogervorst Theo A van Os Senno Verhoef Hanne E J Meijers-Heijboer Juul Wijnen Encarna B Gómez Garcia Marjolijn J Ligtenberg Mieke Kriege J Margriet Collée Margreet G E M Ausems Jan C Oosterwijk Susan Peock Debra Frost Steve D Ellis Radka Platte Elena Fineberg D Gareth Evans Fiona Lalloo Chris Jacobs Ros Eeles Julian Adlard Rosemarie Davidson Trevor Cole Jackie Cook Joan Paterson Fiona Douglas Carole Brewer Shirley Hodgson Patrick J Morrison Lisa Walker Mark T Rogers Alan Donaldson Huw Dorkins Andrew K Godwin Betsy Bove Dominique Stoppa-Lyonnet Claude Houdayer Bruno Buecher Antoine de Pauw Sylvie Mazoyer Alain Calender Mélanie Léoné Brigitte Bressac-de Paillerets Olivier Caron Hagay Sobol Marc Frenay Fabienne Prieur Sandra U Ferrer Isabelle Mortemousque Saundra Buys Mary Daly Alexander Miron Mary U Terry John L Hopper Esther M John Melissa Southey David Goldgar Christian F Singer Anneliese Fink-Retter Muy-Kheng Tea Daphne U Kaulich Thomas V Hansen Finn C Nielsen Rosa B Barkardottir Mia Gaudet Tomas Kirchhoff Vijai Joseph Ana Dutra-Clarke Kenneth Offit Marion Piedmonte Judy Kirk David Cohn Jean Hurteau John Byron James Fiorica Amanda E Toland Marco Montagna Cristina Oliani Evgeny Imyanitov Claudine Isaacs Laima Tihomirova Ignacio Blanco Conxi Lazaro Alex Teulé J Del Valle Simon A Gayther Kunle Odunsi Jenny Gross Beth Y Karlan Edith Olah Soo-Hwang Teo Patricia A Ganz Mary S Beattie Cecelia M Dorfling Elizabeth U van Rensburg Orland Diez Ava Kwong Rita K Schmutzler Barbara Wappenschmidt Christoph Engel Alfons Meindl Nina Ditsch Norbert Arnold Simone Heidemann Dieter Niederacher Sabine Preisler-Adams Dorothea Gadzicki Raymonda Varon-Mateeva Helmut Deissler Andrea Gehrig Christian Sutter Karin Kast Britta Fiebig Dieter Schäfer Trinidad Caldes Miguel de la Hoya Heli Nevanlinna Taru A Muranen Bernard Lespérance Amanda B Spurdle Susan L Neuhausen Yuan C Ding Xianshu Wang Zachary Fredericksen Vernon S Pankratz Noralane M Lindor Paolo Peterlongo Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Bernardo Bonanni Loris Bernard Riccardo Dolcetti Laura Papi Laura Ottini Paolo Radice Mark H Greene Jennifer T Loud Irene L Andrulis Hilmi Ozcelik Anna U Mulligan Gord Glendon Mads Thomassen Anne-Marie Gerdes Uffe B Jensen Anne-Bine Skytte Torben A Kruse Georgia Chenevix-Trench Fergus J Couch Jacques Simard Douglas F Easton

Breast Cancer Res 2012 Feb 20;14(1):R33. Epub 2012 Feb 20.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Worts Causeway, Cambridge CB1 8RN, UK.

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http://dx.doi.org/10.1186/bcr3121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496151PMC
February 2012

Genome-wide association analysis identifies three new breast cancer susceptibility loci.

Authors:
Maya Ghoussaini Olivia Fletcher Kyriaki Michailidou Clare Turnbull Marjanka K Schmidt Ed Dicks Joe Dennis Qin Wang Manjeet K Humphreys Craig Luccarini Caroline Baynes Don Conroy Melanie Maranian Shahana Ahmed Kristy Driver Nichola Johnson Nicholas Orr Isabel dos Santos Silva Quinten Waisfisz Hanne Meijers-Heijboer Andre G Uitterlinden Fernando Rivadeneira Per Hall Kamila Czene Astrid Irwanto Jianjun Liu Heli Nevanlinna Kristiina Aittomäki Carl Blomqvist Alfons Meindl Rita K Schmutzler Bertram Müller-Myhsok Peter Lichtner Jenny Chang-Claude Rebecca Hein Stefan Nickels Dieter Flesch-Janys Helen Tsimiklis Enes Makalic Daniel Schmidt Minh Bui John L Hopper Carmel Apicella Daniel J Park Melissa Southey David J Hunter Stephen J Chanock Annegien Broeks Senno Verhoef Frans B L Hogervorst Peter A Fasching Michael P Lux Matthias W Beckmann Arif B Ekici Elinor Sawyer Ian Tomlinson Michael Kerin Frederik Marme Andreas Schneeweiss Christof Sohn Barbara Burwinkel Pascal Guénel Thérèse Truong Emilie Cordina-Duverger Florence Menegaux Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Roger L Milne M Rosario Alonso Anna González-Neira Javier Benítez Hoda Anton-Culver Argyrios Ziogas Leslie Bernstein Christina Clarke Dur Hermann Brenner Heiko Müller Volker Arndt Christa Stegmaier Christina Justenhoven Hiltrud Brauch Thomas Brüning Shan Wang-Gohrke Ursula Eilber Thilo Dörk Peter Schürmann Michael Bremer Peter Hillemanns Natalia V Bogdanova Natalia N Antonenkova Yuri I Rogov Johann H Karstens Marina Bermisheva Darya Prokofieva Elza Khusnutdinova Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Diether Lambrechts Betul T Yesilyurt Giuseppe Floris Karin Leunen Siranoush Manoukian Bernardo Bonanni Stefano Fortuzzi Paolo Peterlongo Fergus J Couch Xianshu Wang Kristen Stevens Adam Lee Graham G Giles Laura Baglietto Gianluca Severi Catriona McLean Grethe Grenaker Alnaes Vessela Kristensen Anne-Lise Børrensen-Dale Esther M John Alexander Miron Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Saila Kauppila Irene L Andrulis Gord Glendon Anna Marie Mulligan Peter Devilee Christie J van Asperen Rob A E M Tollenaar Caroline Seynaeve Jonine D Figueroa Montserrat Garcia-Closas Louise Brinton Jolanta Lissowska Maartje J Hooning Antoinette Hollestelle Rogier A Oldenburg Ans M W van den Ouweland Angela Cox Malcolm W R Reed Mitul Shah Ania Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Michael Jones Minouk Schoemaker Alan Ashworth Anthony Swerdlow Jonathan Beesley Xiaoqing Chen Kenneth R Muir Artitaya Lophatananon Suthee Rattanamongkongul Arkom Chaiwerawattana Daehee Kang Keun-Young Yoo Dong-Young Noh Chen-Yang Shen Jyh-Cherng Yu Pei-Ei Wu Chia-Ni Hsiung Annie Perkins Ruth Swann Louiza Velentzis Diana M Eccles Will J Tapper Susan M Gerty Nikki J Graham Bruce A J Ponder Georgia Chenevix-Trench Paul D P Pharoah Mark Lathrop Alison M Dunning Nazneen Rahman Julian Peto Douglas F Easton

Nat Genet 2012 Jan 22;44(3):312-8. Epub 2012 Jan 22.

Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, UK.

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http://dx.doi.org/10.1038/ng.1049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653403PMC
January 2012

Common breast cancer susceptibility loci are associated with triple-negative breast cancer.

Cancer Res 2011 Oct 15;71(19):6240-9. Epub 2011 Aug 15.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327299PMC
October 2011

Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers.

Cancer Epidemiol Biomarkers Prev 2011 May 10;20(5):1032-8. Epub 2011 Mar 10.

QueenslanInstitute for Medical Research, Brisbane, Australia.

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http://dx.doi.org/10.1158/1055-9965.EPI-10-0909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089675PMC
May 2011

Exploring the link between MORF4L1 and risk of breast cancer.

Authors:
Griselda Martrat Christopher M Maxwell Emiko Tominaga Montserrat Porta-de-la-Riva Núria Bonifaci Laia Gómez-Baldó Massimo Bogliolo Conxi Lázaro Ignacio Blanco Joan Brunet Helena Aguilar Juana Fernández-Rodríguez Sheila Seal Anthony Renwick Nazneen Rahman Julia Kühl Kornelia Neveling Detlev Schindler María J Ramírez María Castellà Gonzalo Hernández Douglas F Easton Susan Peock Margaret Cook Clare T Oliver Debra Frost Radka Platte D Gareth Evans Fiona Lalloo Rosalind Eeles Louise Izatt Carol Chu Rosemarie Davidson Kai-Ren Ong Jackie Cook Fiona Douglas Shirley Hodgson Carole Brewer Patrick J Morrison Mary Porteous Paolo Peterlongo Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Gaia Roversi Monica Barile Alessandra Viel Barbara Pasini Laura Ottini Anna Laura Putignano Antonella Savarese Loris Bernard Paolo Radice Sue Healey Amanda Spurdle Xiaoqing Chen Jonathan Beesley Matti A Rookus Senno Verhoef Madeleine A Tilanus-Linthorst Maaike P Vreeswijk Christi J Asperen Danielle Bodmer Margreet G E M Ausems Theo A van Os Marinus J Blok Hanne E J Meijers-Heijboer Frans B L Hogervorst David E Goldgar Saundra Buys Esther M John Alexander Miron Melissa Southey Mary B Daly Katja Harbst Ake Borg Johanna Rantala Gisela Barbany-Bustinza Hans Ehrencrona Marie Stenmark-Askmalm Bella Kaufman Yael Laitman Roni Milgrom Eitan Friedman Susan M Domchek Katherine L Nathanson Timothy R Rebbeck Oskar Thor Johannsson Fergus J Couch Xianshu Wang Zachary Fredericksen Daniel Cuadras Víctor Moreno Friederike K Pientka Reinhard Depping Trinidad Caldés Ana Osorio Javier Benítez Juan Bueren Tuomas Heikkinen Heli Nevanlinna Ute Hamann Diana Torres Maria Adelaide Caligo Andrew K Godwin Evgeny N Imyanitov Ramunas Janavicius Olga M Sinilnikova Dominique Stoppa-Lyonnet Sylvie Mazoyer Carole Verny-Pierre Laurent Castera Antoine de Pauw Yves-Jean Bignon Nancy Uhrhammer Jean-Philippe Peyrat Philippe Vennin Sandra Fert Ferrer Marie-Agnès Collonge-Rame Isabelle Mortemousque Lesley McGuffog Georgia Chenevix-Trench Olivia M Pereira-Smith Antonis C Antoniou Julián Cerón Kaoru Tominaga Jordi Surrallés Miguel Angel Pujana

Breast Cancer Res 2011 Apr 5;13(2):R40. Epub 2011 Apr 5.

Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Institute for Biomedical Research (IDIBELL), Gran Via 199, L'Hospitalet del Llobregat 08908, Spain.

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http://dx.doi.org/10.1186/bcr2862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219203PMC
April 2011

Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers.

Authors:
Susan J Ramus Christiana Kartsonaki Simon A Gayther Paul D P Pharoah Olga M Sinilnikova Jonathan Beesley Xiaoqing Chen Lesley McGuffog Sue Healey Fergus J Couch Xianshu Wang Zachary Fredericksen Paolo Peterlongo Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Gaia Roversi Monica Barile Alessandra Viel Anna Allavena Laura Ottini Laura Papi Viviana Gismondi Fabio Capra Paolo Radice Mark H Greene Phuong L Mai Irene L Andrulis Gord Glendon Hilmi Ozcelik Mads Thomassen Anne-Marie Gerdes Torben A Kruse Dorthe Cruger Uffe Birk Jensen Maria Adelaide Caligo Håkan Olsson Ulf Kristoffersson Annika Lindblom Brita Arver Per Karlsson Marie Stenmark Askmalm Ake Borg Susan L Neuhausen Yuan Chun Ding Katherine L Nathanson Susan M Domchek Anna Jakubowska Jan Lubiński Tomasz Huzarski Tomasz Byrski Jacek Gronwald Bohdan Górski Cezary Cybulski Tadeusz Dębniak Ana Osorio Mercedes Durán Maria-Isabel Tejada Javier Benítez Ute Hamann Matti A Rookus Senno Verhoef Madeleine A Tilanus-Linthorst Maaike P Vreeswijk Danielle Bodmer Margreet G E M Ausems Theo A van Os Christi J Asperen Marinus J Blok Hanne E J Meijers-Heijboer Susan Peock Margaret Cook Clare Oliver Debra Frost Alison M Dunning D Gareth Evans Ros Eeles Gabriella Pichert Trevor Cole Shirley Hodgson Carole Brewer Patrick J Morrison Mary Porteous M John Kennedy Mark T Rogers Lucy E Side Alan Donaldson Helen Gregory Andrew Godwin Dominique Stoppa-Lyonnet Virginie Moncoutier Laurent Castera Sylvie Mazoyer Laure Barjhoux Valérie Bonadona Dominique Leroux Laurence Faivre Rosette Lidereau Catherine Nogues Yves-Jean Bignon Fabienne Prieur Marie-Agnès Collonge-Rame Laurence Venat-Bouvet Sandra Fert-Ferrer Alex Miron Saundra S Buys John L Hopper Mary B Daly Esther M John Mary Beth Terry David Goldgar Thomas v O Hansen Lars Jønson Bent Ejlertsen Bjarni A Agnarsson Kenneth Offit Tomas Kirchhoff Joseph Vijai Ana V C Dutra-Clarke Jennifer A Przybylo Marco Montagna Cinzia Casella Evgeny N Imyanitov Ramunas Janavicius Ignacio Blanco Conxi Lázaro Kirsten B Moysich Beth Y Karlan Jenny Gross Mary S Beattie Rita Schmutzler Barbara Wappenschmidt Alfons Meindl Ina Ruehl Britta Fiebig Christian Sutter Norbert Arnold Helmut Deissler Raymonda Varon-Mateeva Karin Kast Dieter Niederacher Dorothea Gadzicki Trinidad Caldes Miguel de la Hoya Heli Nevanlinna Kristiina Aittomäki Jacques Simard Penny Soucy Amanda B Spurdle Helene Holland Georgia Chenevix-Trench Douglas F Easton Antonis C Antoniou

J Natl Cancer Inst 2011 Jan 17;103(2):105-16. Epub 2010 Dec 17.

Department of Gynaecological Oncology, UCL EGA Institute for Women's Health, University College London, London, UK.

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http://dx.doi.org/10.1093/jnci/djq494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107565PMC
January 2011

Genetic testing in Li-Fraumeni syndrome: uptake and psychosocial consequences.

J Clin Oncol 2010 Jun 17;28(18):3008-14. Epub 2010 May 17.

Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Division of Psychosocial Research and Epidemiology, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1200/JCO.2009.27.2112DOI Listing
June 2010

Psychological distress and use of psychosocial support in familial adenomatous polyposis.

Psychooncology 2010 Mar;19(3):289-98

Department of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/pon.1570DOI Listing
March 2010

Physical activity and the risk of breast cancer in BRCA1/2 mutation carriers.

Breast Cancer Res Treat 2010 Feb 13;120(1):235-44. Epub 2009 Aug 13.

Department of Epidemiology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-009-0476-0DOI Listing
February 2010

Attitudes toward genetic testing in childhood and reproductive decision-making for familial adenomatous polyposis.

Eur J Hum Genet 2010 Feb 7;18(2):186-93. Epub 2009 Oct 7.

Department of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2009.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987203PMC
February 2010

Molecular characterization of novel germline deletions affecting SDHD and SDHC in pheochromocytoma and paraganglioma patients.

Endocr Relat Cancer 2009 Sep 22;16(3):929-37. Epub 2009 Jun 22.

Department of Human Genetics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1677/ERC-09-0084DOI Listing
September 2009

Prediction of BRCA1-association in hereditary non-BRCA1/2 breast carcinomas with array-CGH.

Breast Cancer Res Treat 2009 Aug 14;116(3):479-89. Epub 2008 Aug 14.

Division of Experimental Therapy, The Netherlands Cancer Institute NKI/AvL, 1066CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-008-0117-zDOI Listing
August 2009

The contribution of CHEK2 to the TP53-negative Li-Fraumeni phenotype.

Hered Cancer Clin Pract 2009 Feb 17;7(1). Epub 2009 Feb 17.

Family Cancer Clinic, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/1897-4287-7-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664322PMC
February 2009

Two TP53 germline mutations in a classical Li-Fraumeni syndrome family.

Fam Cancer 2007 23;6(3):311-6. Epub 2007 Feb 23.

Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10689-006-9115-7DOI Listing
December 2007

The single-nucleotide polymorphism 309 in the MDM2 gene contributes to the Li-Fraumeni syndrome and related phenotypes.

Eur J Hum Genet 2007 Jan 27;15(1):110-4. Epub 2006 Sep 27.

Family Cancer Clinic, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/sj.ejhg.5201715DOI Listing
January 2007

Late-onset common cancers in a kindred with an Arg213Gln TP53 germline mutation.

Fam Cancer 2006 ;5(2):169-74

Family Cancer Clinic, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10689-005-4789-9DOI Listing
August 2006

Withdrawal from genetic counselling for cancer.

Hered Cancer Clin Pract 2005 Feb 15;3(1):19-27. Epub 2005 Feb 15.

Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

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http://hccpjournal.biomedcentral.com/articles/10.1186/1897-4
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http://dx.doi.org/10.1186/1897-4287-3-1-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837064PMC
February 2005

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.

Cancer Res 2005 Feb;65(3):822-7

Department of Pathology and Familial Cancer Clinic of the Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.

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February 2005