Sendurai A Mani

Sendurai A Mani

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Sendurai A Mani

Publications by authors named "Sendurai A Mani"

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A possible role for epigenetic feedback regulation in the dynamics of the Epithelial-Mesenchymal Transition (EMT).

Phys Biol 2019 Jul 25. Epub 2019 Jul 25.

Department of Bioengineering, Rice University, Houston, Texas, UNITED STATES.

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http://dx.doi.org/10.1088/1478-3975/ab34dfDOI Listing
July 2019

EMT, stemness and tumor plasticity in aggressive variant neuroendocrine prostate cancers.

Biochim Biophys Acta Rev Cancer 2018 12 5;1870(2):229-238. Epub 2018 Jul 5.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Metastasis Research Center, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for Stem Cell and Developmental Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2018.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496942PMC
December 2018

Hybrid epithelial/mesenchymal phenotype(s): The 'fittest' for metastasis?

Biochim Biophys Acta Rev Cancer 2018 12 8;1870(2):151-157. Epub 2018 Jul 8.

Center for Theoretical Biological Physics, Rice University, Houston, TX, USA; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2018.07.001DOI Listing
December 2018

The Non-Coding RNA Journal Club: Highlights on Recent Papers-6.

Noncoding RNA 2018 Sep 18;4(3). Epub 2018 Sep 18.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.

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http://www.mdpi.com/2311-553X/4/3/23
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http://dx.doi.org/10.3390/ncrna4030023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162737PMC
September 2018

Function of Tumor Suppressors in Resistance to Antiandrogen Therapy and Luminal Epithelial Plasticity of Aggressive Variant Neuroendocrine Prostate Cancers.

Front Oncol 2018 15;8:69. Epub 2018 Mar 15.

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.3389/fonc.2018.00069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862804PMC
March 2018

A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers.

Proc Natl Acad Sci U S A 2017 11 30;114(46):E9903-E9912. Epub 2017 Oct 30.

Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037;

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http://dx.doi.org/10.1073/pnas.1716009114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699095PMC
November 2017

Effective models for antimetastatic therapies.

Oncotarget 2017 Nov 6;8(55):93295-93296. Epub 2017 Jun 6.

Xiang H.F. Zhang: Lester and Sue Smith Breast Center, Dan L. Duncan Cancer Center, Department of Molecular and Cellular Biology, McNair Medical Institute, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, USA.

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http://dx.doi.org/10.18632/oncotarget.18379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706786PMC
November 2017

Targeting the Molecular Subtypes of Triple Negative Breast Cancer: Understanding the Diversity to Progress the Field.

Oncologist 2017 09 30;22(9):1086-1093. Epub 2017 May 30.

Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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http://theoncologist.alphamedpress.org/lookup/doi/10.1634/th
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http://dx.doi.org/10.1634/theoncologist.2017-0095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599192PMC
September 2017

The Non-Coding RNA Journal Club: Highlights on Recent Papers-5.

Noncoding RNA 2017 Jun 14;3(2). Epub 2017 Jun 14.

Department of Translational Molecular Pathology and 2Metastasis Research Center, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77054, USA.

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http://dx.doi.org/10.3390/ncrna3020021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831933PMC
June 2017

3D Porous Graphene by Low-Temperature Plasma Welding for Bone Implants.

Adv Mater 2016 Oct 26;28(40):8959-8967. Epub 2016 Aug 26.

Department of Materials Science and Nano Engineering, Rice University, Houston, TX, 77005, USA.

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http://dx.doi.org/10.1002/adma.201603146DOI Listing
October 2016

The Non-Coding RNA Journal Club: Highlights on Recent Papers-4.

Noncoding RNA 2016 Sep 21;2(3). Epub 2016 Sep 21.

Department of Radiation Oncology, UCLA David Geffen School of Medicine, Professor, Director, Translational Research, Los Angeles, California 90024, USA..

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http://dx.doi.org/10.3390/ncrna2030009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831907PMC
September 2016

Erratum: The Non-Coding RNA Journal Club: Highlights on Recent Papers-4. Non-Coding RNA 2016, 2, 9.

Noncoding RNA 2016 09 30;2(4). Epub 2016 Sep 30.

Department of Radiation Oncology, UCLA David Geffen School of Medicine, Professor, Director, Translational Research, Los Angeles, California 90024, USA.

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http://dx.doi.org/10.3390/ncrna2040010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831929PMC
September 2016

Three-Dimensional Porous Sponges from Collagen Biowastes.

ACS Appl Mater Interfaces 2016 Jun 6;8(23):14836-44. Epub 2016 Jun 6.

Department of Materials Science & NanoEngineering, Rice University , Houston, Texas 77005, United States.

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http://dx.doi.org/10.1021/acsami.6b04582DOI Listing
June 2016

GD2 and GD3 synthase: novel drug targets for cancer therapy.

Mol Cell Oncol 2015 Jul-Sep;2(3):e975068. Epub 2015 Mar 9.

Department of Translational Molecular Pathology; The University of Texas MD Anderson Cancer Center; Houston, TX USA; Metastasis Research Center; The University of Texas MD Anderson Cancer Center; Houston, TX USA; Center for Stem Cells and Developmental Biology; The University of Texas MD Anderson Cancer Center; Houston, TX USA.

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http://dx.doi.org/10.4161/23723556.2014.975068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905286PMC
June 2016

Inflammation Mediated Metastasis: Immune Induced Epithelial-To-Mesenchymal Transition in Inflammatory Breast Cancer Cells.

PLoS One 2015 24;10(7):e0132710. Epub 2015 Jul 24.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America; The Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America; The University of Texas Graduate School of Biomedical Sciences at Houston, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132710PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514595PMC
May 2016

Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype.

J R Soc Interface 2016 05;13(118)

Center for Theoretical Biological Physics, Rice University, Houston, TX 77005-1827, USA Department of Chemistry, Rice University, Houston, TX 77005-1827, USA Department of Physics and Astronomy, Rice University, Houston, TX 77005-1827, USA Department of Biosciences, Rice University, Houston, TX 77005-1827, USA

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http://dx.doi.org/10.1098/rsif.2015.1106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892257PMC
May 2016

Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity.

Cancer Res 2016 04 29;76(7):2037-49. Epub 2016 Jan 29.

Department of Integrative Biology & Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas. Graduate School of Biomedical Sciences, Houston, Texas. School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, Texas. Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, Texas. Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1970DOI Listing
April 2016

FOXC2 regulates the G2/M transition of stem cell-rich breast cancer cells and sensitizes them to PLK1 inhibition.

Sci Rep 2016 Apr 11;6:23070. Epub 2016 Apr 11.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Centre, Houston, TX, USA.

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http://dx.doi.org/10.1038/srep23070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827390PMC
April 2016

Mathematical modelling of phenotypic plasticity and conversion to a stem-cell state under hypoxia.

Sci Rep 2016 Feb 3;6:18074. Epub 2016 Feb 3.

Department of Applied Mathematics, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1038/srep18074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738268PMC
February 2016

EMT-induced metabolite signature identifies poor clinical outcome.

Oncotarget 2015 Dec;6(40):42651-60

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.18632/oncotarget.4765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767460PMC
December 2015

Coupling the modules of EMT and stemness: A tunable 'stemness window' model.

Oncotarget 2015 Sep;6(28):25161-74

Center for Theoretical Biological Physics, Rice University, Houston, TX 77005-1827, USA.

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http://dx.doi.org/10.18632/oncotarget.4629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694822PMC
September 2015

A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcome.

Sci Rep 2015 Jun 30;5:11766. Epub 2015 Jun 30.

1] Department of Translational Molecular Pathology [2] Metastasis Research Center [3] Center for Stem Cells and Developmental Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1038/srep11766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485318PMC
June 2015

Tumor cell heterogeneity in Small Cell Lung Cancer (SCLC): phenotypical and functional differences associated with Epithelial-Mesenchymal Transition (EMT) and DNA methylation changes.

PLoS One 2014 24;9(6):e100249. Epub 2014 Jun 24.

Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany; University Furtwangen, Faculty of Medical and Life Sciences, Campus VS-Schwenningen, Villingen-Schwenningen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100249PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069054PMC
March 2015

Towards elucidating the connection between epithelial-mesenchymal transitions and stemness.

J R Soc Interface 2014 Dec;11(101):20140962

Center for Theoretical Biological Physics, Rice University, Houston, TX 77005-1827, USA Department of Biosciences, Rice University, Houston, TX 77005-1827, USA School of Physics and Astronomy and The Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel

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http://dx.doi.org/10.1098/rsif.2014.0962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223923PMC
December 2014

Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties.

Sci Rep 2013 ;3:2687

1] Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA [2] Metastasis Research Center, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA [3] Center for Stem Cells & Developmental Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1038/srep02687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776231PMC
June 2014

Sheep, wolf, or werewolf: cancer stem cells and the epithelial-to-mesenchymal transition.

Cancer Lett 2013 Nov 14;341(1):16-23. Epub 2013 Mar 14.

Department of Integrative Biology and Pharmacology, Medical School, University of Texas Health Science Center, Houston, TX 77030, United States; School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX 77030, United States; Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX 77030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2013.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762892PMC
November 2013

Fluorinated graphene oxide; a new multimodal material for biological applications.

Adv Mater 2013 Oct 27;25(39):5632-7. Epub 2013 Aug 27.

Department of Mechanical, Engineering & Materials Science, Rice University, 6100 Main St. Houston, TX, 77005, USA; Department of Translational Molecular Pathology, MD Anderson Cancer Center, 7435 Fannin Street, Houston, TX, 77054, USA.

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http://dx.doi.org/10.1002/adma201301804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938113PMC
October 2013

Hybrid 2D nanomaterials as dual-mode contrast agents in cellular imaging.

Adv Mater 2012 Jun 10;24(22):2992-8. Epub 2012 May 10.

Department of Mechanical Engineering and Materials Science, Rice University, 6100 Main Street, Houston, TX 77006, USA.

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http://dx.doi.org/10.1002/adma.201200706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395317PMC
June 2012

Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis.

J Clin Invest 2012 Jun 15;122(6):2066-78. Epub 2012 May 15.

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://www.jci.org/articles/view/59735
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http://dx.doi.org/10.1172/JCI59735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591166PMC
June 2012

Alternative origins of stroma in normal organs and disease.

Stem Cell Res 2012 Mar 8;8(2):312-23. Epub 2011 Dec 8.

The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, 1825 Pressler st., Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.scr.2011.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571702PMC
March 2012

Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients.

Breast Cancer Res 2012 Mar 19;14(2):R51. Epub 2012 Mar 19.

Department of Epidemiology, University of North Carolina at Chapel Hill, Campus Box 7435, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1186/bcr3152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446385PMC
March 2012

pIgR: frenemy of inflammation, EMT, and HCC progression.

J Natl Cancer Inst 2011 Nov 24;103(22):1644-5. Epub 2011 Oct 24.

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http://dx.doi.org/10.1093/jnci/djr421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216969PMC
November 2011

HDAC3 at the fulcrum of an epithelial-mesenchymal balance.

Mol Cell 2011 Sep;43(5):697-8

Department of Molecular Pathology, The Center for Stem Cell and Developmental Biology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10972765110063
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http://dx.doi.org/10.1016/j.molcel.2011.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528183PMC
September 2011

Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression.

Breast Cancer Res 2011 Feb 8;13(1):202. Epub 2011 Feb 8.

Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.

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http://dx.doi.org/10.1186/bcr2789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109556PMC
February 2011

Molecular mechanisms of metastasis in breast cancer--clinical applications.

Nat Rev Clin Oncol 2010 Dec 19;7(12):693-701. Epub 2010 Oct 19.

Department of Medical Oncology, Comenius University, School of Medicine, Klenova 1, Bratislava 833 10, Slovakia.

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http://dx.doi.org/10.1038/nrclinonc.2010.171DOI Listing
December 2010

Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer.

J Mammary Gland Biol Neoplasia 2010 Jun 4;15(2):235-52. Epub 2010 Jun 4.

Invasion and Metastasis Unit, St. Vincent's Institute, 9 Princes St, Fitzroy, Melbourne 3065, Australia.

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http://dx.doi.org/10.1007/s10911-010-9175-zDOI Listing
June 2010

Breast cancer metastasis: challenges and opportunities.

Cancer Res 2009 Jun 26;69(12):4951-3. Epub 2009 May 26.

Department of Molecular and Cellular Oncology, University of Texas, M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0099DOI Listing
June 2009

The epithelial-to-mesenchymal transition and cancer stem cells: a coalition against cancer therapies.

J Mammary Gland Biol Neoplasia 2009 Mar 26;14(1):29-43. Epub 2009 Feb 26.

Department of Molecular Pathology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77054, USA.

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http://dx.doi.org/10.1007/s10911-009-9110-3DOI Listing
March 2009

Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways.

Cancer Res 2008 May;68(10):3645-54

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-07-2938DOI Listing
May 2008

Exploring a new twist on tumor metastasis.

Cancer Res 2006 May;66(9):4549-52

Whitehead Institute for Biomedical Research, Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-3850DOI Listing
May 2006

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis.

Cell 2004 Jun;117(7):927-39

Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1016/j.cell.2004.06.006DOI Listing
June 2004