Selvarangan Ponnazhagan

Selvarangan Ponnazhagan

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Selvarangan Ponnazhagan

Selvarangan Ponnazhagan

Publications by authors named "Selvarangan Ponnazhagan"

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71Publications

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Recombinant AAV-CEA Tumor Vaccine in Combination with an Immune Adjuvant Breaks Tolerance and Provides Protective Immunity.

Mol Ther Oncolytics 2019 Mar 13;12:41-48. Epub 2018 Dec 13.

Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1016/j.omto.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329706PMC
March 2019

Structural determinants and genetic modifications enhance BMP2 stability and extracellular secretion.

FASEB Bioadv 2019 Mar 14;1(3):180-190. Epub 2018 Nov 14.

Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35294.

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http://dx.doi.org/10.1096/fba.2018-00023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586023PMC
March 2019

Characterization of immune cell subtypes in three commonly used mouse strains reveals gender and strain-specific variations.

Lab Invest 2019 01 23;99(1):93-106. Epub 2018 Oct 23.

Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.

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http://dx.doi.org/10.1038/s41374-018-0137-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524955PMC
January 2019

Pathology, Chemoprevention, and Preclinical Models for Target Validation in Barrett Esophagus.

Cancer Res 2018 07 29;78(14):3747-3754. Epub 2018 Jun 29.

Bioengineering Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Tehran, Iran.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-0206DOI Listing
July 2018

Effects of Cellular Methylation on Transgene Expression and Site-Specific Integration of Adeno-Associated Virus.

Genes (Basel) 2017 Sep 18;8(9). Epub 2017 Sep 18.

Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.3390/genes8090232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615365PMC
September 2017

Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment.

Sci Rep 2017 08 17;7(1):8678. Epub 2017 Aug 17.

Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.

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http://dx.doi.org/10.1038/s41598-017-09062-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561077PMC
August 2017

Resveratrol induces mitochondria-mediated, caspase-independent apoptosis in murine prostate cancer cells.

Oncotarget 2017 Mar;8(13):20895-20908

Cancer Biology Research and Training, Department of Biological Sciences, Alabama State University, Montgomery, AL, USA.

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http://dx.doi.org/10.18632/oncotarget.14947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400554PMC
March 2017

Location of tumor affects local and distant immune cell type and number.

Immun Inflamm Dis 2017 03 23;5(1):85-94. Epub 2017 Feb 23.

Department of Pathology University of Alabama at Birmingham Birmingham Alabama USA.

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http://dx.doi.org/10.1002/iid3.144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322166PMC
March 2017

Immature myeloid cells are critical for enhancing bone fracture healing through angiogenic cascade.

Bone 2016 12 21;93:113-124. Epub 2016 Sep 21.

Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2016.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443259PMC
December 2016

Detection of Merkel cell polyomavirus in formalin-fixed, paraffin-embedded tissue of Merkel cell carcinoma and correlation with prognosis.

Rom J Morphol Embryol 2014 ;55(3 Suppl):1057-62

Department of Pathology, University of Michigan, Ann Arbor, MI, USA;

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September 2015

SOCS3 Deficiency in Myeloid Cells Promotes Tumor Development: Involvement of STAT3 Activation and Myeloid-Derived Suppressor Cells.

Cancer Immunol Res 2015 Jul 3;3(7):727-40. Epub 2015 Feb 3.

Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570503PMC
July 2015

The dual targeting of immunosuppressive cells and oxidants promotes effector and memory T-cell functions against lung cancer.

Oncoimmunology 2014 Jan;3(1):e27401

Department of Medicine; The University of Alabama at Birmingham; Birmingham, AL USA.

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http://dx.doi.org/10.4161/onci.27401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976979PMC
January 2014

Enhancement of antitumor immunity in lung cancer by targeting myeloid-derived suppressor cell pathways.

Cancer Res 2013 Nov 1;73(22):6609-20. Epub 2013 Oct 1.

Authors' Affiliations: Departments of Pathology, Medicine, Microbiology, and Pediatrics, The University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854493PMC
November 2013

Myeloid-derived suppressor cells as osteoclast progenitors: a novel target for controlling osteolytic bone metastasis.

Cancer Res 2013 Aug 25;73(15):4606-10. Epub 2013 Jul 25.

Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732563PMC
August 2013

Myeloid-derived suppressor cells as a novel target for the control of osteolytic bone disease.

Oncoimmunology 2013 May;2(5):e24064

Department of Pathology; University of Alabama at Birmingham; Birmingham, AL USA.

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http://dx.doi.org/10.4161/onci.24064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667900PMC
May 2013

Muscle-directed anti-Aβ single-chain antibody delivery via AAV1 reduces cerebral Aβ load in an Alzheimer's disease mouse model.

J Mol Neurosci 2013 Feb 4;49(2):277-88. Epub 2012 Sep 4.

Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, P.O. Box 1649, Peoria, IL, 61656, USA.

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http://dx.doi.org/10.1007/s12031-012-9877-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545079PMC
February 2013

Role of plasmacytoid dendritic cells in breast cancer bone dissemination.

Oncoimmunology 2013 Feb;2(2):e22983

Department of Pathology; The University of Alabama at Birmingham; Birmingham, AL USA.

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http://dx.doi.org/10.4161/onci.22983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601166PMC
February 2013

Myeloid-derived suppressor cells function as novel osteoclast progenitors enhancing bone loss in breast cancer.

Cancer Res 2013 Jan 14;73(2):672-82. Epub 2012 Dec 14.

Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama 35294-2182, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-2202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548966PMC
January 2013

Differential effects of low-dose decitabine on immune effector and suppressor responses in melanoma-bearing mice.

Cancer Immunol Immunother 2012 Sep 5;61(9):1441-50. Epub 2012 Feb 5.

Taussig Cancer Institute, R40, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1007/s00262-012-1204-xDOI Listing
September 2012

Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect.

Bone 2012 Apr 9;50(4):1012-8. Epub 2012 Feb 9.

Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1016/j.bone.2012.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339043PMC
April 2012

Noggin is novel inducer of mesenchymal stem cell adipogenesis: implications for bone health and obesity.

J Biol Chem 2012 Apr 20;287(15):12241-9. Epub 2012 Feb 20.

Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M111.293613
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http://dx.doi.org/10.1074/jbc.M111.293613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320975PMC
April 2012

LL-37 as a therapeutic target for late stage prostate cancer.

Prostate 2011 May 18;71(6):659-70. Epub 2010 Oct 18.

Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama 35291-000, USA.

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http://dx.doi.org/10.1002/pros.21282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025071PMC
May 2011

Conditionally replicating adenovirus expressing TIMP2 for ovarian cancer therapy.

Clin Cancer Res 2011 Feb 29;17(3):538-49. Epub 2010 Nov 29.

Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0007, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816714PMC
February 2011

Regulation of the activity of an adeno-associated virus vector cancer vaccine administered with synthetic Toll-like receptor agonists.

Vaccine 2010 Nov 27;28(50):7837-43. Epub 2010 Oct 27.

Taussig Cancer Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X100142
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http://dx.doi.org/10.1016/j.vaccine.2010.09.086DOI Listing
November 2010

Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in diseases of the skeleton.

J Cell Biochem 2010 Oct;111(2):249-57

Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0007, USA.

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http://dx.doi.org/10.1002/jcb.22701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946500PMC
October 2010

Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4.

Lab Invest 2009 Nov 14;89(11):1221-8. Epub 2009 Sep 14.

Department of Cell Biology, University of Alabama at Birmingham, Birmingham, 1530 3rd Avenue South, 533 LHRB, Birmingham, AL 35294, USA.

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http://www.nature.com/articles/labinvest200997
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http://dx.doi.org/10.1038/labinvest.2009.97DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905319PMC
November 2009

Tumoristatic effects of endostatin in prostate cancer is dependent on androgen receptor status.

Prostate 2009 Jul;69(10):1055-66

Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama 35294-0007, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087284PMC
http://dx.doi.org/10.1002/pros.20952DOI Listing
July 2009

High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not always accompanied by reduction in p27Kip1.

Int J Oncol 2009 May;34(5):1425-31

Biochemistry and Molecular Biology Department, Drug Discovery Division, Southern Research Institute, Birmingham, AL 35255, USA.

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May 2009

Pulmonary angiogenesis in a rat model of hepatopulmonary syndrome.

Gastroenterology 2009 Mar 3;136(3):1070-80. Epub 2008 Dec 3.

Department of Internal Medicine and Liver Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1053/j.gastro.2008.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827330PMC
March 2009

Therapeutic potential of mesenchymal stem cells producing interferon-alpha in a mouse melanoma lung metastasis model.

Stem Cells 2008 Sep 10;26(9):2332-8. Epub 2008 Jul 10.

Department of Pathology, LHRB 513, 701 19th Street South, University of Alabama at Birmingham, Birmingham, Alabama 35294-0007, USA.

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http://dx.doi.org/10.1634/stemcells.2008-0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940717PMC
September 2008

Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: implications for proliferation and migration in vitro and metastasis in vivo.

Clin Cancer Res 2008 Aug;14(15):4961-70

Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama 35294-0007, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-4604DOI Listing
August 2008

Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of breast cancer bone metastasis.

Mol Ther 2008 May 18;16(5):871-8. Epub 2008 Mar 18.

Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama 35294-0007, USA.

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http://dx.doi.org/10.1038/mt.2008.48DOI Listing
May 2008

Bone homing of mesenchymal stem cells by ectopic alpha 4 integrin expression.

FASEB J 2007 Dec 10;21(14):3917-27. Epub 2007 Jul 10.

Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35294-0007, USA.

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http://dx.doi.org/10.1096/fj.07-8275comDOI Listing
December 2007

Notch1 augments intracellular trafficking of adeno-associated virus type 2.

J Virol 2007 Feb 6;81(4):2069-73. Epub 2006 Dec 6.

Department of Pathology, LHRB 513, 701, 19th Street South, University of Alabama at Birmingham, Birmingham, AL 35294-0007, USA.

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http://dx.doi.org/10.1128/JVI.01811-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797595PMC
February 2007

Anti-Abeta single-chain antibody delivery via adeno-associated virus for treatment of Alzheimer's disease.

Neurobiol Dis 2006 Sep;23(3):502-11

Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, PO Box 1649, Peoria, IL 61656, USA.

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http://dx.doi.org/10.1016/j.nbd.2006.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2459226PMC
September 2006

Airway epithelium directed gene therapy for cystic fibrosis.

Med Chem 2006 Sep;2(5):499-503

Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294-0007, USA.

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September 2006

Determination of osteoprogenitor-specific promoter activity in mouse mesenchymal stem cells by recombinant adeno-associated virus transduction.

Biochim Biophys Acta 2005 Nov 15;1731(2):95-103. Epub 2005 Sep 15.

Department of Pathology, The University of Alabama at Birmingham, LHRB 513, 701, 19th Street South, Birmingham, AL 35294-0007, USA.

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http://dx.doi.org/10.1016/j.bbaexp.2005.08.007DOI Listing
November 2005

Protein transduction of dendritic cells for NY-ESO-1-based immunotherapy of myeloma.

Cancer Res 2005 Nov;65(21):10041-9

Myeloma Institute for Research and Therapy, Section for Gene and Immunotherapy, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1383DOI Listing
November 2005

Genomic stability of self-complementary adeno-associated virus 2 during early stages of transduction in mouse muscle in vivo.

Hum Gene Ther 2005 Sep;16(9):1047-57

Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1089/hum.2005.16.1047DOI Listing
September 2005

Recombinant adeno-associated virus 2-mediated antiangiogenic prevention in a mouse model of intraperitoneal ovarian cancer.

Clin Cancer Res 2005 Feb;11(3):1342-7

Department of Pathology, University of Alabama at Birmingham, 19th Street South, Birmingham, AL 35294-0007, USA.

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February 2005

Gene therapy for osteoinduction.

Curr Gene Ther 2004 Sep;4(3):287-96

Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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September 2004

Anti-angiogenic gene therapy for cancer (review).

Int J Oncol 2004 Aug;25(2):335-43

Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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August 2004

Delivery of DNA to tumor cells in vivo using adeno-associated virus.

Methods Mol Biol 2004 ;246:237-43

Department of Pathology, University of Alabama, Birmingham, AL, USA.

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http://dx.doi.org/10.1385/1-59259-650-9:237DOI Listing
March 2004

Parvovirus vectors for cancer gene therapy.

Expert Opin Biol Ther 2004 Jan;4(1):53-64

Department of Pathology, LHRB 513, 701 19th Street South, University of Alabama at Birmingham, Birmingham, AL 35294-0007, USA.

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http://dx.doi.org/10.1517/14712598.4.1.53 DOI Listing
January 2004

Adenoassociated virus vectors for genetic immunization.

Immunol Res 2002 ;26(1-3):247-53

Department of Pathology, University of Alabama at Birmingham, 35294-0007, USA.

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http://link.springer.com/10.1385/IR:26:1-3:247
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http://dx.doi.org/10.1385/IR:26:1-3:247DOI Listing
April 2003

Conjugate-based targeting of recombinant adeno-associated virus type 2 vectors by using avidin-linked ligands.

J Virol 2002 Dec;76(24):12900-7

Department of Pathology, LHRB 513, The University of Alabama at Birmingham, 701 19th Street South, Birmingham, AL 35294, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC136730PMC
http://dx.doi.org/10.1128/jvi.76.24.12900-12907.2002DOI Listing
December 2002