Selina M Luger

Selina M Luger

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Selina M Luger

Publications by authors named "Selina M Luger"

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Optimizing Chimeric Antigen Receptor T-Cell Therapy for Adults With Acute Lymphoblastic Leukemia.

J Clin Oncol 2020 Feb 9;38(5):415-422. Epub 2019 Dec 9.

Division of Hematology Oncology, Abramson Cancer Center, Cell Therapy and Transplant, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.19.01892DOI Listing
February 2020

Acute myeloid leukemia: How to treat the fit patient over age 75?

Authors:
Selina M Luger

Best Pract Res Clin Haematol 2019 12 19;32(4):101105. Epub 2019 Oct 19.

Leukemia Program, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Boulevard, 12th Floor South Pavilion, Philadelphia, PA, 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2019.101105DOI Listing
December 2019

Longitudinal targeted next-generation sequencing in a patient with acute myeloid leukaemia.

Br J Haematol 2019 Sep 17;186(6):801. Epub 2019 Jun 17.

Division of Precision and Computational Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.16048DOI Listing
September 2019

Relapsed T Cell ALL: Current Approaches and New Directions.

Curr Hematol Malig Rep 2019 04;14(2):83-93

Division of Hematology and Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s11899-019-00501-3DOI Listing
April 2019

Maintenance therapy in acute myeloid leukemia: What is the future?

Semin Hematol 2019 04 28;56(2):102-109. Epub 2018 Aug 28.

Division of Hematology and Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2018.08.006DOI Listing
April 2019

Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract.

Bone Marrow Transplant 2019 02 24;54(2):212-217. Epub 2018 May 24.

Blood and Marrow Transplantation Program, Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://www.nature.com/articles/s41409-018-0236-z
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http://dx.doi.org/10.1038/s41409-018-0236-zDOI Listing
February 2019

Higher Donor Apheresis Blood Volumes Are Associated with Reduced Relapse Risk and Improved Survival in Reduced-Intensity Allogeneic Transplantations with Unrelated Donors.

Biol Blood Marrow Transplant 2018 06 2;24(6):1203-1208. Epub 2018 Feb 2.

Blood and Marrow Transplantation Program and Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2018.01.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993582PMC
June 2018

How can one optimize induction therapy in AML?

Authors:
Selina M Luger

Best Pract Res Clin Haematol 2017 12 4;30(4):301-305. Epub 2017 Oct 4.

Abramson Cancer Center, University of Pennsylvania, Perelman School of Medicine, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2017.10.001DOI Listing
December 2017

Minimal Residual Disease in Acute Myeloid Leukemia.

Curr Treat Options Oncol 2017 01;18(1)

Division of Hematology/Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd., South Pavilion 12th floor, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s11864-017-0447-3DOI Listing
January 2017

Clinical Utility of Next-Generation Sequencing for Oncogenic Mutations in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2016 11 28;22(11):1961-1967. Epub 2016 Jul 28.

Blood and Marrow Transplantation Program and Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, New York. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067228PMC
http://dx.doi.org/10.1016/j.bbmt.2016.07.018DOI Listing
November 2016

Extramedullary Disease in Adult Acute Myeloid Leukemia Is Common but Lacks Independent Significance: Analysis of Patients in ECOG-ACRIN Cancer Research Group Trials, 1980-2008.

J Clin Oncol 2016 10;34(29):3544-3553

Chezi Genzel and Jacob M. Rowe, Shaare Zedek Medical Center, Jerusalem, Israel; Chezi Ganzel, Dan Douer, and Martin S. Tallman, Memorial Sloan Kettering Cancer Center; Elisabeth M. Paietta, Montefiore Medical Center; Peter H. Wiernik, St. Luke's-Roosevelt Medical Center, New York, NY; Judith Manola and Ju-Whei Lee, Dana-Farber Cancer Institute, Boston, MA; Hugo F. Fernandez, H. Lee Moffitt Cancer Institute, Tampa, FL; Mark R. Litzow, Mayo Clinic, Rochester, MN; Selina M. Luger, University of Pennsylvania, Philadelphia, PA; Hillard M. Lazarus, University Hospitals Case Medical Center, Cleveland, OH; and Larry D. Cripe, Indiana University Cancer Center, Indianapolis, IN.

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http://dx.doi.org/10.1200/JCO.2016.67.5892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074349PMC
October 2016

A Modified Integrated Genetic Model for Risk Prediction in Younger Patients with Acute Myeloid Leukemia.

PLoS One 2016 6;11(4):e0153016. Epub 2016 Apr 6.

Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153016PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822876PMC
August 2016

Nelarabine, cyclosphosphamide and etoposide for adults with relapsed T-cell acute lymphoblastic leukaemia and lymphoma.

Br J Haematol 2016 07 25;174(2):332-4. Epub 2015 Sep 25.

Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.13771DOI Listing
July 2016

A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia.

JCI Insight 2016 Jun;1(9)

Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1172/jci.insight.87323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951094PMC
June 2016

Revisiting maintenance therapy in acute myeloid leukemia with novel agents.

Curr Opin Hematol 2016 Mar;23(2):175-80

Division of Hematology and Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000223DOI Listing
March 2016

Combined B12 and folate deficiency presenting as an aggressive hematologic malignancy.

Am J Hematol 2015 Oct 29;90(10):964-5. Epub 2015 Apr 29.

Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/ajh.23987DOI Listing
October 2015

Outpatient Autologous Stem Cell Transplantation for Patients With Myeloma.

Clin Lymphoma Myeloma Leuk 2015 Sep 6;15(9):536-40. Epub 2015 Jun 6.

Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2015.05.006DOI Listing
September 2015

How I treat adults with relapsed or refractory Philadelphia chromosome-negative acute lymphoblastic leukemia.

Blood 2015 Jul 12;126(5):589-96. Epub 2015 May 12.

Hematology-Oncology Division, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-09-55
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http://dx.doi.org/10.1182/blood-2014-09-551937DOI Listing
July 2015

Approach to patients with primary refractory acute myeloid leukemia.

Curr Opin Hematol 2015 Mar;22(2):97-107

Division of Hematology and Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000115DOI Listing
March 2015

Early donor chimerism levels predict relapse and survival after allogeneic stem cell transplantation with reduced-intensity conditioning.

Biol Blood Marrow Transplant 2014 Nov 10;20(11):1758-66. Epub 2014 Jul 10.

Abramson Cancer Center and the Division of Hematology & Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.bbmt.2014.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194246PMC
November 2014

Will FLT3 inhibitors fulfill their promise in acute meyloid leukemia?

Curr Opin Hematol 2014 Mar;21(2):72-8

aDepartment of Oncology, Division of Hematologic Malignancies, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland bAbramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142569PMC
March 2014

Characteristics and outcome of acute myeloid leukemia in patients with a prior history of autoimmune disease.

Leuk Lymphoma 2013 Jun 19;54(6):1235-41. Epub 2013 Feb 19.

Abramson Cancer Center, Division of Hematology/Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.3109/10428194.2012.736982DOI Listing
June 2013

New strategies for the evaluation of the nadir bone marrow following induction in acute myeloid leukemia.

Curr Opin Hematol 2013 Mar;20(2):93-9

Department of Medicine, University of Wisconsin School of Medicine and Public Health, Wisconsin Institutes for Medical Research, Madison, Wisconsin 53705, USA.

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http://dx.doi.org/10.1097/MOH.0b013e32835d8207DOI Listing
March 2013

A paraneoplastic syndrome characterized by extremity swelling with associated inflammatory infiltrate heralds aggressive transformation of myelodysplastic syndromes/myeloproliferative neoplasms to acute myeloid leukemia: a case series.

Case Rep Hematol 2012 25;2012:582950. Epub 2012 Jun 25.

Division of Hematology-Oncology, Department of Medicine, Abramson Cancer Center, University of Pennsylvania, 34th Street and Civic Center Blvd, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1155/2012/582950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420449PMC
August 2012

Beyond morphology: minimal residual disease detection in acute myeloid leukemia.

Curr Opin Hematol 2012 Mar;19(2):82-8

Division of Hematology/Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MOH.0b013e3283501325DOI Listing
March 2012

Is a nadir bone marrow required and, if so, what to do with residual disease?

Authors:
Selina M Luger

Best Pract Res Clin Haematol 2011 Dec 4;24(4):527-32. Epub 2011 Nov 4.

Leukemia Program, University of Pennsylvania, Abramson Cancer Center, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.beha.2011.09.009DOI Listing
December 2011

Treating the elderly patient with acute myelogenous leukemia.

Authors:
Selina M Luger

Hematology Am Soc Hematol Educ Program 2010 ;2010:62-9

Hospital of the University of Pennsylvania, Perelman Center for Advanced Medicine, and Hematologic Malignancies and Stem Cell Transplant Program, Hematology-Oncology Division, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1182/asheducation-2010.1.62DOI Listing
April 2011

Salvage therapy for relapsed or refractory acute myeloid leukemia.

Ther Adv Hematol 2011 Apr;2(2):73-82

Division of Hematology-Oncology, Department of Internal Medicine, and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1177/2040620711402533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573399PMC
April 2011

Anthracycline dose intensification in acute myeloid leukemia.

N Engl J Med 2009 Sep;361(13):1249-59

Department of Blood and Marrow Transplantation, Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1056/NEJMoa0904544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480917PMC
September 2009

Update on the therapy for myelodysplastic syndrome.

Am J Hematol 2009 Mar;84(3):177-86

Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/ajh.21352DOI Listing
March 2009

Severe eosinophilia as a manifestation of acute graft-versus-host disease.

Oncology 2008 15;75(3-4):134-6. Epub 2008 Sep 15.

Department of Internal Medicine, Temple University Hospital, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1159/000155224DOI Listing
November 2008

Valproic acid for the treatment of myeloid malignancies.

Cancer 2008 May;112(10):2324-5; author reply 2325

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http://dx.doi.org/10.1002/cncr.23433DOI Listing
May 2008

Novel strategies for relapsed and refractory acute myeloid leukemia.

Curr Opin Hematol 2008 Mar;15(2):108-14

Abramson Cancer Center and Division of Hematology and Oncology, Department of Internal Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MOH.0b013e3282f463d2DOI Listing
March 2008

Increased cerebral blood flow after leukapheresis for acute myelogenous leukemia.

Am J Hematol 2007 Dec;82(12):1110-2

Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1002/ajh.21006DOI Listing
December 2007

Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study.

Blood 2007 Feb 10;109(3):944-50. Epub 2006 Oct 10.

Royal Free and University College London Medical School, and Christie Hospital National Health Service Trust, Manchester, UK.

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http://dx.doi.org/10.1182/blood-2006-05-018192DOI Listing
February 2007

A predictive model for the detection of tumor lysis syndrome during AML induction therapy.

Leuk Lymphoma 2006 May;47(5):877-83

Hematologic Malignancies Program, Division of Hematology and Oncology, Department of Internal Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1080/10428190500404662DOI Listing
May 2006

A phase 1 trial of donor lymphocyte infusions expanded and activated ex vivo via CD3/CD28 costimulation.

Blood 2006 Feb 3;107(4):1325-31. Epub 2005 Nov 3.

Stem Cell Transplant Program, Division of Hematology-Oncology, 16 Penn Tower, 3400 Spruce St, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1182/blood-2005-08-3373DOI Listing
February 2006

The role of hematopoietic stem cell transplantation in myelodysplastic syndrome.

Oncology (Williston Park) 2005 Apr;19(4):533-42; discussion 542-4, 547-8

Hematologic Malignancies and Stem Cell Transplant Program, University of Pennsylvania, Abramson Cancer Center, Philadelphia 19104, USA.

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April 2005

Leukemic gingival infiltrate as an indicator of chemotherapeutic failure following monoclonal antibody therapy: a case report.

Spec Care Dentist 2003 ;23(3):108-10

Division of Oral Medicine, School of Dental Medicine, 4001 Spruce Street, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.1754-4505.2003.tb01670.xDOI Listing
January 2004

Oligodeoxynucleotide-mediated inhibition of c-myb gene expression in autografted bone marrow: a pilot study.

Blood 2002 Feb;99(4):1150-8

Division of Hematology/Oncology and the Stem Cell Biology/Therapeutics Program, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.

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http://dx.doi.org/10.1182/blood.v99.4.1150DOI Listing
February 2002