Publications by authors named "Seiko Ohno"

100Publications

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls.

Authors:
Roddy Walsh Najim Lahrouchi Rafik Tadros Florence Kyndt Charlotte Glinge Pieter G Postema Ahmad S Amin Eline A Nannenberg James S Ware Nicola Whiffin Francesco Mazzarotto Doris Škorić-Milosavljević Christian Krijger Elena Arbelo Dominique Babuty Hector Barajas-Martinez Britt M Beckmann Stéphane Bézieau J Martijn Bos Jeroen Breckpot Oscar Campuzano Silvia Castelletti Candan Celen Sebastian Clauss Anniek Corveleyn Lia Crotti Federica Dagradi Carlo de Asmundis Isabelle Denjoy Sven Dittmann Patrick T Ellinor Cristina Gil Ortuño Carla Giustetto Jean-Baptiste Gourraud Daisuke Hazeki Minoru Horie Taisuke Ishikawa Hideki Itoh Yoshiaki Kaneko Jørgen K Kanters Hiroki Kimoto Maria-Christina Kotta Ingrid P C Krapels Masahiko Kurabayashi Julieta Lazarte Antoine Leenhardt Bart L Loeys Catarina Lundin Takeru Makiyama Jacques Mansourati Raphaël P Martins Andrea Mazzanti Stellan Mörner Carlo Napolitano Kimie Ohkubo Michael Papadakis Boris Rudic Maria Sabater Molina Frédéric Sacher Hatice Sahin Georgia Sarquella-Brugada Regina Sebastiano Sanjay Sharma Mary N Sheppard Keiko Shimamoto M Benjamin Shoemaker Birgit Stallmeyer Johannes Steinfurt Yuji Tanaka David J Tester Keisuke Usuda Paul A van der Zwaag Sonia Van Dooren Lut Van Laer Annika Winbo Bo G Winkel Kenichiro Yamagata Sven Zumhagen Paul G A Volders Steven A Lubitz Charles Antzelevitch Pyotr G Platonov Katja E Odening Dan M Roden Jason D Roberts Jonathan R Skinner Jacob Tfelt-Hansen Maarten P van den Berg Morten S Olesen Pier D Lambiase Martin Borggrefe Kenshi Hayashi Annika Rydberg Tadashi Nakajima Masao Yoshinaga Johan B Saenen Stefan Kääb Pedro Brugada Tomas Robyns Daniela F Giachino Michael J Ackerman Ramon Brugada Josep Brugada Juan R Gimeno Can Hasdemir Pascale Guicheney Silvia G Priori Eric Schulze-Bahr Naomasa Makita Peter J Schwartz Wataru Shimizu Takeshi Aiba Jean-Jacques Schott Richard Redon Seiko Ohno Vincent Probst Elijah R Behr Julien Barc Connie R Bezzina

Genet Med 2020 Sep 7. Epub 2020 Sep 7.

Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.1038/s41436-020-00946-5DOI Listing
September 2020

Missense Mutation Causes Nonsense-Mediated mRNA Decay and Severe Dilated Cardiomyopathy.

Circ Genom Precis Med 2020 Oct 20;13(5):435-443. Epub 2020 Aug 20.

Department of Cardiovascular Medicine (K.K., S.O., M.F., T.O., M.H.), Shiga University of Medical Science, Otsu.

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http://dx.doi.org/10.1161/CIRCGEN.119.002853DOI Listing
October 2020

An NGS-based genotyping in LQTS; minor genes are no longer minor.

J Hum Genet 2020 Jul 17. Epub 2020 Jul 17.

Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1038/s10038-020-0805-zDOI Listing
July 2020

Postoperative supraventricular tachycardia and polymorphic ventricular tachycardia due to a novel SCN5A variant: a case report of a rare comorbidity that is difficult to diagnose.

BMC Cardiovasc Disord 2020 Jul 2;20(1):315. Epub 2020 Jul 2.

Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, 520-2192, Japan.

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http://dx.doi.org/10.1186/s12872-020-01601-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333335PMC
July 2020

Left-dominant arrhythmogenic cardiomyopathy with a nonsense mutation in DSP.

ESC Heart Fail 2020 Jun 27. Epub 2020 Jun 27.

Department of Cardiovascular Medicine and Diagnostic Radiology, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1002/ehf2.12790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524242PMC
June 2020

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome.

Authors:
Najim Lahrouchi Rafik Tadros Lia Crotti Yuka Mizusawa Pieter G Postema Leander Beekman Roddy Walsh Kanae Hasegawa Julien Barc Marko Ernsting Kari L Turkowski Andrea Mazzanti Britt M Beckmann Keiko Shimamoto Ulla-Britt Diamant Yanushi D Wijeyeratne Yu Kucho Tomas Robyns Taisuke Ishikawa Elena Arbelo Michael Christiansen Annika Winbo Reza Jabbari Steven A Lubitz Johannes Steinfurt Boris Rudic Bart Loeys M Ben Shoemaker Peter E Weeke Ryan Pfeiffer Brianna Davies Antoine Andorin Nynke Hofman Federica Dagradi Matteo Pedrazzini David J Tester J Martijn Bos Georgia Sarquella-Brugada Óscar Campuzano Pyotr G Platonov Birgit Stallmeyer Sven Zumhagen Eline A Nannenberg Jan H Veldink Leonard H van den Berg Ammar Al-Chalabi Christopher E Shaw Pamela J Shaw Karen E Morrison Peter M Andersen Martina Müller-Nurasyid Daniele Cusi Cristina Barlassina Pilar Galan Mark Lathrop Markus Munter Thomas Werge Marta Ribasés Tin Aung Chiea C Khor Mineo Ozaki Peter Lichtner Thomas Meitinger J Peter van Tintelen Yvonne Hoedemaekers Isabelle Denjoy Antoine Leenhardt Carlo Napolitano Wataru Shimizu Jean-Jacques Schott Jean-Baptiste Gourraud Takeru Makiyama Seiko Ohno Hideki Itoh Andrew D Krahn Charles Antzelevitch Dan M Roden Johan Saenen Martin Borggrefe Katja E Odening Patrick T Ellinor Jacob Tfelt-Hansen Jonathan R Skinner Maarten P van den Berg Morten Salling Olesen Josep Brugada Ramón Brugada Naomasa Makita Jeroen Breckpot Masao Yoshinaga Elijah R Behr Annika Rydberg Takeshi Aiba Stefan Kääb Silvia G Priori Pascale Guicheney Hanno L Tan Christopher Newton-Cheh Michael J Ackerman Peter J Schwartz Eric Schulze-Bahr Vincent Probst Minoru Horie Arthur A Wilde Michael W T Tanck Connie R Bezzina

Circulation 2020 Jul 20;142(4):324-338. Epub 2020 May 20.

Amsterdam UMC, University of Amsterdam, Heart Center; Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, The Netherlands (N.L., R.T., Y.M., P.G.P., L.B., R.W., N.H., H.L.T., A.A.W., C.R.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.045956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382531PMC
July 2020

Erratum to "Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients".

Stem Cells Int 2020 23;2020:8765895. Epub 2020 Jan 23.

Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1155/2020/8765895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204173PMC
January 2020

SCN5A mutation identified in a patient with short-coupled variant of torsades de pointes.

Pacing Clin Electrophysiol 2020 05 8;43(5):456-461. Epub 2020 May 8.

Department of Cardiovascular Medicine, Shiga University of Medical Science, Shiga, Japan.

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http://dx.doi.org/10.1111/pace.13924DOI Listing
May 2020

Identification of transmembrane protein 168 mutation in familial Brugada syndrome.

FASEB J 2020 May 16;34(5):6399-6417. Epub 2020 Mar 16.

Division of Molecular Medical Biochemistry, Department of Biochemistry and Molecular Biology, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1096/fj.201902991RDOI Listing
May 2020

High Prevalence of Late-Appearing T-Wave in Patients With Long QT Syndrome Type 8.

Circ J 2020 03 12;84(4):559-568. Epub 2020 Mar 12.

Department of Cardiovascular Medicine, Shiga University of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-19-1101DOI Listing
March 2020

Multivariate analysis of TU wave complex on electrocardiogram in Andersen-Tawil syndrome with KCNJ2 mutations.

Ann Noninvasive Electrocardiol 2020 05 14;25(3):e12721. Epub 2019 Nov 14.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1111/anec.12721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358888PMC
May 2020

Cardiac Arrest Associated with Both an Anomalous Left Coronary Artery and KCNE1 Polymorphism.

Int Heart J 2019 Jul 12;60(4):1003-1005. Epub 2019 Jul 12.

Department of Cardiology, Fujita Health University School of Medicine.

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http://dx.doi.org/10.1536/ihj.18-581DOI Listing
July 2019

Long QT syndrome with a de novo CALM2 mutation in a 4-year-old boy.

Pediatr Int 2019 Sep;61(9):852-858

Department of Pediatrics, Toyama Prefectural Central Hospital, Toyama, Japan.

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http://dx.doi.org/10.1111/ped.13959DOI Listing
September 2019

A de novo gain-of-function KCND3 mutation in early repolarization syndrome.

Heart Rhythm 2019 11 4;16(11):1698-1706. Epub 2019 Jun 4.

Department of Cardiovascular Medicine, Shiga University of Medical Science, Otsu, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2019.05.033DOI Listing
November 2019

Left-Dominant Arrhythmogenic Cardiomyopathy With Heterozygous Mutations in DSP and MYBPC3.

Circ Cardiovasc Imaging 2019 06 30;12(6):e008913. Epub 2019 May 30.

Department of Cardiology, Asahikawa Medical University (N. Sakamoto, S.H., A.M., K.A., N. Sato, N.H.).

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http://dx.doi.org/10.1161/CIRCIMAGING.119.008913DOI Listing
June 2019

Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients.

Stem Cells Int 2019 6;2019:7532657. Epub 2019 Mar 6.

Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1155/2019/7532657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431403PMC
March 2019

Transcriptional cofactor Vgll2 is required for functional adaptations of skeletal muscle induced by chronic overload.

J Cell Physiol 2019 Feb 6. Epub 2019 Feb 6.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan.

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http://dx.doi.org/10.1002/jcp.28239DOI Listing
February 2019

Identification of a novel exon3 deletion of RYR2 in a family with catecholaminergic polymorphic ventricular tachycardia.

Ann Noninvasive Electrocardiol 2019 05 7;24(3):e12623. Epub 2019 Jan 7.

Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.

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http://dx.doi.org/10.1111/anec.12623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850420PMC
May 2019

Dynamic QT Changes in Long QT Syndrome Type 8.

Circ J 2019 06 22;83(7):1614. Epub 2018 Dec 22.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-18-0984DOI Listing
June 2019

Novel roles of Drosophila FUS and Aub responsible for piRNA biogenesis in neuronal disorders.

Brain Res 2019 04 19;1708:207-219. Epub 2018 Dec 19.

Department of Applied Biology, Kyoto Institute of Technology, Kyoto 606-8585, Japan; The Center for Advanced Insect Research, Kyoto Institute of Technology, Kyoto 606-8585, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2018.12.028DOI Listing
April 2019

Medical Castration is a Rare but Possible Trigger of Torsade de Pointes and Ventricular Fibrillation.

Int Heart J 2019 Jan 5;60(1):193-198. Epub 2018 Dec 5.

Department of Cardiovascular Medicine, Faculty of Medical Sciences, University of Fukui.

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https://www.jstage.jst.go.jp/article/ihj/advpub/0/advpub_18-
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http://dx.doi.org/10.1536/ihj.18-127DOI Listing
January 2019

A tryptophan residue in the caffeine-binding site of the ryanodine receptor regulates Ca sensitivity.

Commun Biol 2018 23;1:98. Epub 2018 Jul 23.

Department of Cellular and Molecular Pharmacology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.

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http://dx.doi.org/10.1038/s42003-018-0103-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123685PMC
July 2018

A novel mutation identified in a patient with Timothy syndrome without syndactyly exerts both marked loss- and gain-of-function effects.

HeartRhythm Case Rep 2018 Jul 31;4(7):273-277. Epub 2018 Mar 31.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S22140271183004
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http://dx.doi.org/10.1016/j.hrcr.2018.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050422PMC
July 2018

Autonomic Function and QT Interval During Night-Time Sleep in Infant Long QT Syndrome.

Circ J 2018 07 27;82(8):2152-2159. Epub 2018 Jun 27.

Epidemiology and Biostatistics, Kagawa Nutrition University.

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http://dx.doi.org/10.1253/circj.CJ-18-0048DOI Listing
July 2018

Electrical storm in an infant with short-coupled variant of torsade de pointes.

J Arrhythm 2018 Jun 14;34(3):315-318. Epub 2018 May 14.

Department of Cardiovascular and Respiratory Medicine Shiga University of Medical Science Otsu Shiga Japan.

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http://dx.doi.org/10.1002/joa3.12071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009772PMC
June 2018

Three cases of catecholaminergic polymorphic ventricular tachycardia with prolonged QT intervals including two cases of compound mutations.

J Arrhythm 2018 Jun 6;34(3):291-293. Epub 2018 Apr 6.

Department of Pediatrics National Hospital Organization Kagoshima Medical Center Kagoshima Japan.

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http://dx.doi.org/10.1002/joa3.12053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010000PMC
June 2018

Differential Diagnosis Between Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Type 1 - Modified Schwartz Score.

Circ J 2018 08 21;82(9):2269-2276. Epub 2018 Jun 21.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-17-1032DOI Listing
August 2018

Copy number variations of SCN5A in Brugada syndrome.

Heart Rhythm 2018 08 21;15(8):1179-1188. Epub 2018 Mar 21.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2018.03.033DOI Listing
August 2018

Population pharmacokinetics and pharmacogenomics of apixaban in Japanese adult patients with atrial fibrillation.

Br J Clin Pharmacol 2018 06 16;84(6):1301-1312. Epub 2018 Apr 16.

Laboratory of Clinical Pharmaceutics and Therapeutics, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga, 525-8577, Japan.

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http://dx.doi.org/10.1111/bcp.13561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980466PMC
June 2018

Association of zygotic piRNAs derived from paternal elements with hybrid dysgenesis in .

Mob DNA 2018 6;9. Epub 2018 Feb 6.

1Department of Applied Biology, Kyoto Institute of Technology, Hashigamicyo Matsugasaki, Sakyo-ku, Kyoto, 606-8585 Japan.

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http://dx.doi.org/10.1186/s13100-018-0110-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800288PMC
February 2018

A challenge for mutation specific risk stratification in long QT syndrome type 1.

J Cardiol 2018 07 10;72(1):56-65. Epub 2018 Feb 10.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jjcc.2017.12.011DOI Listing
July 2018

Bradycardia Is a Specific Phenotype of Catecholaminergic Polymorphic Ventricular Tachycardia Induced by RYR2 Mutations.

Intern Med 2018 Jul 9;57(13):1813-1817. Epub 2018 Feb 9.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Japan.

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http://dx.doi.org/10.2169/internalmedicine.9843-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064684PMC
July 2018

Unique genetic background and outcome of non-Caucasian Japanese probands with arrhythmogenic right ventricular dysplasia/cardiomyopathy.

Mol Genet Genomic Med 2017 11 13;5(6):639-651. Epub 2017 Aug 13.

Department of Cardiovascular Medicine, Shiga University of Medical Science, Otsu, Japan.

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http://doi.wiley.com/10.1002/mgg3.311
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http://dx.doi.org/10.1002/mgg3.311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702570PMC
November 2017

Novel intracellular transport-refractory mutations in KCNH2 identified in patients with symptomatic long QT syndrome.

J Cardiol 2018 04 14;71(4):401-408. Epub 2017 Nov 14.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Shiga, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jjcc.2017.10.004DOI Listing
April 2018

Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report.

Clin Biochem 2018 Feb 2;52:148-152. Epub 2017 Nov 2.

Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1016/j.clinbiochem.2017.10.019DOI Listing
February 2018

Diversity of element piRNA production among M' and Q strains and its association with P-M hybrid dysgenesis in .

Mob DNA 2017 23;8:13. Epub 2017 Oct 23.

Department of Applied Biology, Kyoto Institute of Technology, Hashigamicyo, Matsugasaki, Sakyo-ku, Kyoto, 606-8585 Japan.

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http://dx.doi.org/10.1186/s13100-017-0096-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654125PMC
October 2017

Quantitative analysis of PKP2 and neighbouring genes in a patient with arrhythmogenic right ventricular cardiomyopathy caused by heterozygous PKP2 deletion.

Europace 2017 Apr;19(4):644-650

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Tsukiwa-cho, Seta, Otsu 520-2192, Japan.

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http://dx.doi.org/10.1093/europace/euw038DOI Listing
April 2017

How Should We Treat School-Aged Children With Borderline QT Prolongation?

Authors:
Seiko Ohno

Circ J 2017 Apr 7;81(5):640-641. Epub 2017 Apr 7.

Center for Epidemiologic Research in Asia, Shiga University of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-17-0292DOI Listing
April 2017

Genotype-Phenotype Correlation of Mutation for the Clinical and Electrocardiographic Characteristics of Probands With Brugada Syndrome: A Japanese Multicenter Registry.

Circulation 2017 Jun 24;135(23):2255-2270. Epub 2017 Mar 24.

From Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan (K.Y., T.A., K.K., S.K. S.Y., H.O., W.S.); Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Japan (M.H., S. Ohno); Department of Cardiovascular Medicine, University of Tokyo, Japan (K.Y.); Department of Cardiopulmonary Medicine, Keio University, Tokyo, Japan (S. Ogawa, K.F.); Division of Cardiology, Niigata University Graduate School of Medical and Dental Sciences, Japan (Y.A., H.W.); Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan (T.O., H.M.); Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Ishikawa, Japan (M.Y., K.H.); Molecular Physiology, Nagasaki University Graduate School of Biomedical Sciences, Japan (N.M.); Department of Cardiology, Tokyo Metropolitan Hiroo Hospital, Japan (H.S.); Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan (T.T.); Division of Cardiology, Yamaguchi University Graduate School of Medicine, Japan (A.S.); Department of Cardiology, Tokyo Women's Medical University, Japan (N.H.); Department of Cardiology, St Marianna University of Medicine, Kanagawa, Japan (R.K.); Department of Cardiovascular Medicine, Hiroshima University, Japan (Y.N.); Department of Cardiovascular Medicine, Osaka City University, Japan (M.T.); Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Japan (T.M.); Laboratory of Molecular Genetics, National Cerebral and Cardiovascular Center, Osaka, Japan (Y.M.); Departments of Cardiovascular Diseases, Pediatrics, and Molecular Pharmacology & Experimental Therapeutics; Divisions of Heart Rhythm Services and Pediatric Cardiology, Windland Smith Rice Sudden Death Genomics Laboratory, Mayo Clinic, Rochester, MN (J.D.K., M.J.A.); and Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan (W.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.027983DOI Listing
June 2017

Cardiac conduction defects and Brugada syndrome: A family with overlap syndrome carrying a nonsense SCN5A mutation.

J Arrhythm 2017 Feb 2;33(1):35-39. Epub 2016 Jul 2.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Ohtsu, Shiga, Japan.

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http://dx.doi.org/10.1016/j.joa.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300865PMC
February 2017

The genetic background of arrhythmogenic right ventricular cardiomyopathy.

Authors:
Seiko Ohno

J Arrhythm 2016 Oct 26;32(5):398-403. Epub 2016 Feb 26.

Center of Epidemiologic Research for Asia, Cardiovascular Department, Shiga University of Medical Science, Seta-Tsukinowa-cho, Otsu, Shiga 520-2192, Japan.

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http://dx.doi.org/10.1016/j.joa.2016.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063271PMC
October 2016

Early repolarization and risk of arrhythmia events in long QT syndrome.

Int J Cardiol 2016 Nov 11;223:540-542. Epub 2016 Aug 11.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Shiga, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.08.215DOI Listing
November 2016

Inherited catecholaminergic polymorphic ventricular tachycardia due to RYR2 mutation.

Pediatr Int 2016 Jun 25;58(6):512-515. Epub 2016 May 25.

Department of Cardiology, Shizuoka Children's Hospital Medical Center, Iwata City, Shizuoka, Japan.

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http://dx.doi.org/10.1111/ped.12910DOI Listing
June 2016

Fetal arrhythmogenic right ventricular cardiomyopathy with double mutations in TMEM43.

Pediatr Int 2016 May 3;58(5):409-411. Epub 2016 Feb 3.

Department of Pediatrics, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.

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http://dx.doi.org/10.1111/ped.12832DOI Listing
May 2016

Multigenerational Inheritance of Long QT Syndrome Type 2 in a Japanese Family.

Intern Med 2016 1;55(3):259-62. Epub 2016 Feb 1.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Japan.

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http://dx.doi.org/10.2169/internalmedicine.55.6014DOI Listing
August 2016

Pediatric Cohort With Long QT Syndrome - KCNH2 Mutation Carriers Present Late Onset But Severe Symptoms.

Circ J 2016 26;80(3):696-702. Epub 2016 Jan 26.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-15-0933DOI Listing
November 2016

LMNA cardiomyopathy detected in Japanese arrhythmogenic right ventricular cardiomyopathy cohort.

J Cardiol 2016 10 25;68(4):346-51. Epub 2015 Nov 25.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Shiga, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jjcc.2015.10.013DOI Listing
October 2016

Cardiac sodium channel mutation associated with epinephrine-induced QT prolongation and sinus node dysfunction.

Heart Rhythm 2016 Jan 14;13(1):289-98. Epub 2015 Aug 14.

Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.hrthm.2015.08.021DOI Listing
January 2016

High Frequency of Early Repolarization and Brugada-Type Electrocardiograms in Hypercalcemia.

Ann Noninvasive Electrocardiol 2016 Jan 11;21(1):30-40. Epub 2015 Aug 11.

Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1111/anec.12303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931523PMC
January 2016

A Common Mutation of Long QT Syndrome Type 1 in Japan.

Circ J 2015 29;79(9):2026-30. Epub 2015 Jun 29.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science.

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May 2016

Gender Differences in the Inheritance Mode of RYR2 Mutations in Catecholaminergic Polymorphic Ventricular Tachycardia Patients.

PLoS One 2015 26;10(6):e0131517. Epub 2015 Jun 26.

Cardiovascular and Respiratory Department, Shiga University of Medical Science, Otsu, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482545PMC
May 2016

Novel SCN10A variants associated with Brugada syndrome.

Europace 2016 Jun 4;18(6):905-11. Epub 2015 Apr 4.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga 520-2192, Japan

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http://dx.doi.org/10.1093/europace/euv078DOI Listing
June 2016

Efficacy and safety of flecainide for ventricular arrhythmias in patients with Andersen-Tawil syndrome with KCNJ2 mutations.

Heart Rhythm 2015 Mar 10;12(3):596-603. Epub 2014 Dec 10.

Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan; Department of Advanced Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2014.12.009DOI Listing
March 2015

Brugada syndrome in spinal and bulbar muscular atrophy.

Neurology 2014 May 23;82(20):1813-21. Epub 2014 Apr 23.

From the Department of Neurology (A.A., M.K., K.S., H.B., N.S., A.H., T. Mano, Y.H., H.N., H.W., G.S.), Nagoya University Graduate School of Medicine; Institute for Advanced Research (H.B.), Nagoya University; Department of Speech Pathology and Audiology (M.Y.), Aichi-Gakuin University School of Health Science, Nisshin; Department of Cardiovascular Medicine (T. Makiyama), Kyoto University Graduate School of Medicine; Department of Cardiovascular and Respiratory Medicine (S.O., M.F., M.H.), Shiga University of Medical Science, Ohtsu; and Division of Cardiology (S.-i.M.), Department of Internal Medicine, Fujita Health University School of Medicine, Toyoake, Japan.

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http://dx.doi.org/10.1212/WNL.0000000000000434DOI Listing
May 2014

Author reply: To PMID 24394973.

Europace 2014 Dec 12;16(12):1864-5. Epub 2014 Apr 12.

Department of cardiovascular, Shiga University of Medical Sciences, Ohtsu, Japan

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December 2014

Long QT syndrome type 8: novel CACNA1C mutations causing QT prolongation and variant phenotypes.

Europace 2014 Dec 12;16(12):1828-37. Epub 2014 Apr 12.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga 520-2192, Japan

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December 2014

Gain-of-function KCNH2 mutations in patients with Brugada syndrome.

J Cardiovasc Electrophysiol 2014 May 30;25(5):522-530. Epub 2014 Jan 30.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1111/jce.12361DOI Listing
May 2014

Exon 3 deletion of RYR2 encoding cardiac ryanodine receptor is associated with left ventricular non-compaction.

Europace 2014 Nov 6;16(11):1646-54. Epub 2014 Jan 6.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Seta-Tsukinowa-cho, Otsu, Shiga 520-2192, Japan

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http://dx.doi.org/10.1093/europace/eut382DOI Listing
November 2014

Nonsense-mediated mRNA decay due to a CACNA1C splicing mutation in a patient with Brugada syndrome.

Heart Rhythm 2014 Apr 7;11(4):629-34. Epub 2013 Dec 7.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Shiga, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2013.12.011DOI Listing
April 2014

A molecular mechanism for adrenergic-induced long QT syndrome.

J Am Coll Cardiol 2014 Mar 30;63(8):819-27. Epub 2013 Oct 30.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan. Electronic address:

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http://content.onlinejacc.org/data/Journals/JAC/929815/81648
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March 2014