Seiji Yano

Seiji Yano

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Seiji Yano

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Pharmacokinetics of Neoadjuvant Axitinib Influenced the Efficacy in Patients With Advanced Renal Cell Carcinoma.

J Clin Pharmacol 2020 Feb 19;60(2):256-263. Epub 2019 Sep 19.

Department of Urology, Graduate School of Medicine, Yamaguchi University, Ube, Yamaguchi, Japan.

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http://dx.doi.org/10.1002/jcph.1521DOI Listing
February 2020

Osimertinib Overcomes Alectinib Resistance Caused by Amphiregulin in a Leptomeningeal Carcinomatosis Model of ALK-Rearranged Lung Cancer.

J Thorac Oncol 2020 Jan 21. Epub 2020 Jan 21.

Division of Medical Oncology, Kanazawa University Cancer Research Institute, Kanazawa, Japan; Nano Life Science Institute, Kanazawa University, Kanazawa University, Kanazawa, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2020.01.001DOI Listing
January 2020

Caput Medusae-like Venous Dilatation in Lung Cancer.

Intern Med 2019 11 10;58(22):3341-3342. Epub 2019 Jul 10.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Japan.

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http://dx.doi.org/10.2169/internalmedicine.2577-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911767PMC
November 2019

EGFR-TKI resistance promotes immune escape in lung cancer via increased PD-L1 expression.

Mol Cancer 2019 11 20;18(1):165. Epub 2019 Nov 20.

Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.

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http://dx.doi.org/10.1186/s12943-019-1073-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864970PMC
November 2019

Clinical Characteristics Associated With Lenvatinib-induced Fistula and Tumor-related Bleeding in Patients With Thyroid Cancer.

Anticancer Res 2019 Jul;39(7):3871-3878

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.21873/anticanres.13537DOI Listing
July 2019

Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.

Nat Chem Biol 2019 06 17;15(6):598-606. Epub 2019 May 17.

Division of Tumor Dynamics and Regulation, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1038/s41589-019-0285-7DOI Listing
June 2019

Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach.

Int J Mol Sci 2019 Jun 17;20(12). Epub 2019 Jun 17.

Division of Tumor Dynamics and Regulation, Cancer Research Institute, Kanazawa University, Kakuma, Kanazawa 920-1192, Japan.

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http://dx.doi.org/10.3390/ijms20122955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628191PMC
June 2019

A case of advanced pancreatic neuroendocrine tumor in which octreotide long-acting repeatable was effective after failure of everolimus and sunitinib.

Int Cancer Conf J 2019 Jan 7;8(1):24-28. Epub 2018 Nov 7.

Outpatient Cancer Chemotherapy Center, Houju Memorial Hospital, 11-71, Midorigaoka, Nomi, Ishikawa 923-1226 Japan.

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http://dx.doi.org/10.1007/s13691-018-0348-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498279PMC
January 2019

Pulmonary carcinosarcoma showing an obvious response to pazopanib: a case report.

BMC Pulm Med 2018 Dec 12;18(1):193. Epub 2018 Dec 12.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, 13-1, Takara-machi, Kanazawa, Ishikawa, 920-0934, Japan.

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https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890
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http://dx.doi.org/10.1186/s12890-018-0757-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291996PMC
December 2018

Distinct dependencies on receptor tyrosine kinases in the regulation of MAPK signaling between BRAF V600E and non-V600E mutant lung cancers.

Oncogene 2018 03 19;37(13):1775-1787. Epub 2018 Jan 19.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Ishikawa, Japan.

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http://dx.doi.org/10.1038/s41388-017-0035-9DOI Listing
March 2018

Acquired resistance to targeted drugs and novel therapy to overcome the resistance.

Authors:
Seiji Yano

Ann Oncol 2017 Oct;28 Suppl 9:ix70

Division of Medical Oncology, Cancer Research Institute, Kanazawa University.

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http://dx.doi.org/10.1093/annonc/mdx617DOI Listing
October 2017

Resistance mediated by alternative receptor tyrosine kinases in FGFR1-amplified lung cancer.

Carcinogenesis 2017 10;38(11):1063-1072

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Ishikawa 920-0934, Japan.

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http://dx.doi.org/10.1093/carcin/bgx091DOI Listing
October 2017

and anti-tumor activity of alectinib in tumor cells with NCOA4-RET.

Oncotarget 2017 Sep 16;8(43):73766-73773. Epub 2017 May 16.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.18632/oncotarget.17900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650298PMC
September 2017

Histone Deacetylase 3 Inhibition Overcomes Deletion Polymorphism-Mediated Osimertinib Resistance in Mutant Lung Cancer.

Clin Cancer Res 2017 Jun 16;23(12):3139-3149. Epub 2016 Dec 16.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2271DOI Listing
June 2017

Liver parenchyma transection-first approach in hemihepatectomy with en bloc caudate lobectomy for hilar cholangiocarcinoma: A safe technique to secure favorable surgical outcomes.

J Surg Oncol 2017 Jun 23;115(8):963-970. Epub 2017 Mar 23.

Department of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.

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http://doi.wiley.com/10.1002/jso.24612
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http://dx.doi.org/10.1002/jso.24612DOI Listing
June 2017

Copy Number Gain Is Associated with Gefitinib Resistance in Leptomeningeal Carcinomatosis of -mutant Lung Cancer.

Mol Cancer Ther 2017 03 30;16(3):506-515. Epub 2017 Jan 30.

Division of Medical Oncology, Kanazawa University Cancer Research Institute, Kanazawa, Japan.

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http://dx.doi.org/10.1158/1535-7163.MCT-16-0522DOI Listing
March 2017

Proteolytic inactivation of anti-angiogenic vasohibin-1 by cancer cells.

J Biochem 2016 Oct 11;160(4):227-232. Epub 2016 May 11.

Department of Vascular Biology, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-Machi, Aoba-ku, Sendai 980-8575, Japan

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http://dx.doi.org/10.1093/jb/mvw030DOI Listing
October 2016

Elevated prothrombin time/international normalized ratio associated with concurrent administration of regorafenib and warfarin in a patient with advanced colorectal cancer.

J Pharm Health Care Sci 2016 8;2:15. Epub 2016 Jul 8.

Outpatient Cancer Chemotherapy Center, Houju Memorial Hospital, 11-71, Midorigaoka, Nomi-shi, Ishikawa 923-1226 Japan ; Department of Medical Oncology, Cancer Research Institute, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-0934 Japan.

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http://dx.doi.org/10.1186/s40780-016-0050-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937497PMC
July 2016

[Combined Therapy with Targeted Drugs in Lung Cancer].

Authors:
Seiji Yano

Gan To Kagaku Ryoho 2016 Apr;43(4):413-8

Dept. of Medical Oncology, Cancer Research Institute, Kanazawa University.

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April 2016

Organ-specific efficacy of HSP90 inhibitor in multiple-organ metastasis model of chemorefractory small cell lung cancer.

Int J Cancer 2016 Mar 13;138(5):1281-9. Epub 2015 Oct 13.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1002/ijc.29858DOI Listing
March 2016

TMPRSS4 Expression as a Marker of Recurrence in Patients with Lung Cancer.

Anticancer Res 2016 Jan;36(1):121-7

Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.

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January 2016

Akt Kinase-Interacting Protein 1 Signals through CREB to Drive Diffuse Malignant Mesothelioma.

Cancer Res 2015 Oct 20;75(19):4188-97. Epub 2015 Aug 20.

Department of Internal Medicine, The Ohio State University Medical Center, Columbus, Ohio.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0858DOI Listing
October 2015

[Molecular mechanisms of targeted drug resistance in lung cancer and its therapeutic strategy].

Authors:
Seiji Yano

Nihon Rinsho 2015 Aug;73(8):1378-83

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August 2015

Intraductal papillary mucinous carcinoma of the pancreas associated with pancreas divisum: a case report and review of the literature.

BMC Gastroenterol 2015 Jul 8;15:78. Epub 2015 Jul 8.

Department of Digestive and General Surgery, Shimane University Faculty of Medicine, 89-1 Enyacho, Izumo, Shimane, 693-8501, Japan.

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http://dx.doi.org/10.1186/s12876-015-0313-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495851PMC
July 2015

Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2.

Nat Commun 2015 Jul 9;6:7679. Epub 2015 Jul 9.

Department of Cancer Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan.

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http://dx.doi.org/10.1038/ncomms8679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510653PMC
July 2015

[Notable adverse events of ALK inhibitors in patients with ALK rearranged non-small-cell lung cancer].

Nihon Rinsho 2015 Feb;73 Suppl 2:256-60

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February 2015

Lack of association between the BIM deletion polymorphism and the risk of lung cancer with and without EGFR mutations.

J Thorac Oncol 2015 Jan;10(1):59-66

*Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan; †Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Aichi, Japan; ‡Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan; §Thoracic Surgery, Aichi Cancer Center Hospital, Aichi, Japan; ‖Department of Thoracic Oncology, Aichi Cancer Center Hospital, Aichi, Japan; ¶VCU Philips Institute for Oral Health Research, School of Dentistry and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA; #Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Aichi, Japan; **Department of Surgery, Division of Thoracic Surgery, Kinki University Faculty of Medicine, Osaka-Sayama, Japan; and ††Department of Preventive Medicine, Kyushu University Faculty of Medical Sciences, Fukuoka, Japan.

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http://dx.doi.org/10.1097/JTO.0000000000000371DOI Listing
January 2015

Distinct allelic expression patterns of imprinted in adenocarcinoma and squamous cell carcinoma of the lung.

Oncol Lett 2014 Dec 29;8(6):2561-2564. Epub 2014 Sep 29.

Department of Internal Medicine, Kanazawa University Cancer Research Institute, Ishikawa 920-1192, Japan.

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https://www.spandidos-publications.com/10.3892/ol.2014.2572
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http://dx.doi.org/10.3892/ol.2014.2572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214443PMC
December 2014

Clinical significance of epidermal growth factor receptor tyrosine kinase inhibitors: sensitivity and resistance.

Respir Investig 2014 Nov 31;52(6):348-56. Epub 2014 Oct 31.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-0934, Japan; Cancer Center, Kanazawa University Hospital, 13-1 Takara-machi, Kanazawa, Ishikawa 920-0934, Japan.

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http://dx.doi.org/10.1016/j.resinv.2014.10.002DOI Listing
November 2014

Expression of Akt kinase-interacting protein 1, a scaffold protein of the PI3K/PDK1/Akt pathway, in pancreatic cancer.

Pancreas 2014 Oct;43(7):1093-100

From the *Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan; †Division of Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan; and ‡Department of Gastroenterological Surgery and §Division of Pathology, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1097/MPA.0000000000000168DOI Listing
October 2014

Triple inhibition of EGFR, Met, and VEGF suppresses regrowth of HGF-triggered, erlotinib-resistant lung cancer harboring an EGFR mutation.

J Thorac Oncol 2014 Jun;9(6):775-83

Divisions of *Medical Oncology and †Tumor Dynamics and Regulation, Cancer Research Institute, Kanazawa University, Kanazawa, Japan; and ‡Tsukuba Research Center, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.

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http://dx.doi.org/10.1097/JTO.0000000000000170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132034PMC
June 2014

Not just gRASping at flaws: finding vulnerabilities to develop novel therapies for treating KRAS mutant cancers.

Cancer Sci 2014 May 26;105(5):499-505. Epub 2014 Mar 26.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan.

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http://dx.doi.org/10.1111/cas.12383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317830PMC
May 2014

Antitumor effect and antiangiogenic potential of the mTOR inhibitor temsirolimus against malignant pleural mesothelioma.

Oncol Rep 2014 Mar 30;31(3):1109-15. Epub 2013 Dec 30.

Department of General and Cardiothoracic Surgery, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.3892/or.2013.2948DOI Listing
March 2014

[Programs for continuing medical education: B session; 4. Progress in lung cancer therapy].

Authors:
Seiji Yano

Nihon Naika Gakkai Zasshi 2014 Mar;103(3):699-704

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http://dx.doi.org/10.2169/naika.103.699DOI Listing
March 2014

The current state of molecularly targeted drugs targeting HGF/Met.

Jpn J Clin Oncol 2014 Jan 25;44(1):9-12. Epub 2013 Dec 25.

*Division of Medical Oncology, Cancer Research Institute, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-0934, Japan.

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https://academic.oup.com/jjco/article-lookup/doi/10.1093/jjc
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http://dx.doi.org/10.1093/jjco/hyt188DOI Listing
January 2014

Paracrine activation of MET promotes peritoneal carcinomatosis in scirrhous gastric cancer.

Cancer Sci 2013 Dec 13;104(12):1640-6. Epub 2013 Nov 13.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1111/cas.12301DOI Listing
December 2013

A novel targeting therapy of malignant mesothelioma using anti-podoplanin antibody.

J Immunol 2013 Jun 20;190(12):6239-49. Epub 2013 May 20.

Central Office for Clinical Pharmacy Training, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima 770-8503, Japan.

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http://dx.doi.org/10.4049/jimmunol.1300448DOI Listing
June 2013

[Cancer targeted therapy and resistance signals].

Authors:
Seiji Yano

Seikagaku 2013 Jun;85(6):475-83

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, 13-1, Takaramachi, Kanazawa, Ishikawa 920-0934, Japan.

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June 2013

EGFR-TKI resistance due to BIM polymorphism can be circumvented in combination with HDAC inhibition.

Cancer Res 2013 Apr 4;73(8):2428-34. Epub 2013 Feb 4.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3479DOI Listing
April 2013

Therapeutic antitumor efficacy of anti-epidermal growth factor receptor antibody, cetuximab, against malignant pleural mesothelioma.

Int J Oncol 2012 Nov 24;41(5):1610-8. Epub 2012 Aug 24.

Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, Yonago-shi, Tottori-ken 683-8504, Japan.

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http://dx.doi.org/10.3892/ijo.2012.1607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583649PMC
November 2012

Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer.

Mol Cancer Ther 2012 Oct 25;11(10):2149-57. Epub 2012 Jul 25.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-0934, Japan.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-0195DOI Listing
October 2012

Prognostic value of acquired resistance-related molecules in Japanese patients with NSCLC treated with an EGFR-TKI.

Anticancer Res 2012 Sep;32(9):3785-90

Second Department of Surgery, University of Occupational and Environmental Health, Kitakyushu, Japan.

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September 2012

Ligand-triggered resistance to molecular targeted drugs in lung cancer: roles of hepatocyte growth factor and epidermal growth factor receptor ligands.

Cancer Sci 2012 Jul 9;103(7):1189-94. Epub 2012 May 9.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Ishikawa.

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http://dx.doi.org/10.1111/j.1349-7006.2012.02279.xDOI Listing
July 2012

Hsp90 inhibition overcomes HGF-triggering resistance to EGFR-TKIs in EGFR-mutant lung cancer by decreasing client protein expression and angiogenesis.

J Thorac Oncol 2012 Jul;7(7):1078-85

Division of Medical Oncology, †Division of Tumor Dynamics and Regulation, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1097/JTO.0b013e3182519a2cDOI Listing
July 2012

Endoscopic findings of upper gastrointestinal lesions in patients with pancreatic cancer.

JOP 2012 Jul 10;13(4):420-6. Epub 2012 Jul 10.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.6092/1590-8577/749DOI Listing
July 2012

A case of pancreatic neuroendocrine tumor in a patient with neurofibromatosis-1.

World J Surg Oncol 2012 Jul 23;10:153. Epub 2012 Jul 23.

Department of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.

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http://wjso.biomedcentral.com/articles/10.1186/1477-7819-10-
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http://dx.doi.org/10.1186/1477-7819-10-153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545965PMC
July 2012

Hepatocyte growth factor induces resistance to anti-epidermal growth factor receptor antibody in lung cancer.

J Thorac Oncol 2012 Feb;7(2):272-80

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S155608641533228
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http://dx.doi.org/10.1097/JTO.0b013e3182398e69DOI Listing
February 2012

Genetically engineered humanized anti-ganglioside GM2 antibody against multiple organ metastasis produced by GM2-expressing small-cell lung cancer cells.

Cancer Sci 2011 Dec 30;102(12):2157-63. Epub 2011 Sep 30.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Ishikawa, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2011.02093.xDOI Listing
December 2011

E7080 suppresses hematogenous multiple organ metastases of lung cancer cells with nonmutated epidermal growth factor receptor.

Mol Cancer Ther 2011 Jul 6;10(7):1218-28. Epub 2011 May 6.

Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima 770-8503, Japan.

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http://dx.doi.org/10.1158/1535-7163.MCT-10-0707DOI Listing
July 2011

Reconstruction of the esophagojejunostomy by double stapling method using EEA™ OrVil™ in laparoscopic total gastrectomy and proximal gastrectomy.

World J Surg Oncol 2011 May 20;9:55. Epub 2011 May 20.

Department of Digestive and General Surgery, Shimane University School of Medicine, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan.

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http://dx.doi.org/10.1186/1477-7819-9-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118377PMC
May 2011