Publications by authors named "Sefa Yurtbay"

2 Publications

  • Page 1 of 1

Frontal QRS-T angle as a predictive marker for myocardial damage in acute carbon monoxide poisoning.

Hum Exp Toxicol 2021 Nov 24:9603271211043477. Epub 2021 Nov 24.

Faculty of Medicine, Department of Emergency Medicine, 52954Sivas Cumhuriyet University, Sivas, Turkey.

Introduction: The present study was undertaken to investigate the prognostic value of the frontal QRS-T angle associated with adverse cardiac outcomes in patients with carbon monoxide (CO) poisoning in early stages in the emergency department.

Materials And Methods: The data of 212 patients with CO poisoning who were admitted to the ED between January 2010 and May 2020 were retrospectively analyzed. The frontal QRS-T angle was obtained from the automatic reports of the EKG device.

Results: Compared to patients without myocardial damage, among patients with myocardial damage, statistically high creatinine, creatine kinase MB, cardiac troponin I, and frontal QRS-T angle values were found ( < 0.001 for all parameters), while the saturation of arterial blood pH and arterial oxygen values were found to be lower ( = 0.002 and < 0.001, respectively). The frontal QRS-T angle values were correlated with creatine kinase, creatine kinase-MB, cardiac troponin I, and oxygen saturation (SpO) in arterial blood (r = 0. 232, = 0.001; r = 0. 253, = < 0.001; r = 0. 389, = < 0.001; r = -0. 198, = 0.004, respectively). The optimum cut-off value of the frontal QRS-T angle was found to be 44.5 (area under the curve: 0.901, 95% confidence interval: 0.814-0.988, sensitivity: 87%, specificity: 84%).

Conclusions: The frontal QRS-T angle, a simple and inexpensive parameter that can be easily obtained from 12-lead surface electrocardiography, can be used as an early indicator in the detection of myocardial damage in patients with CO poisoning.
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http://dx.doi.org/10.1177/09603271211043477DOI Listing
November 2021

Serum TLR9 and NF-B Biochemical Markers in Patients with Acute Pancreatitis on Admission.

Emerg Med Int 2020 1;2020:1264714. Epub 2020 Feb 1.

Lazarski University, Medical Faculty, Warsaw, Poland.

Aim: The aim of this study was to investigate the serum TLR9 and NF-B levels in patients for the diagnosis and prognostication of AP in the emergency department.

Methods: In the current study, we looked at the TLR9 and NF-B levels in patients for the diagnosis and prognostication of AP in the emergency department.

Results: Of the patients with acute pancreatitis, 22 (49%) were male and 23 (51%) were female. The mean age of the patient group was 62 years, with a range of 25-95 years. The control group consisted of 19 (43.1%) male and 25 (56.9%) female patients. The serum TLR9 and NF-B levels in patients for the diagnosis and prognostication of AP in the emergency department. < 0.001 and 8.04 ± 1.76 vs. 4.76 ± 1.13; < 0.001 and 8.04 ± 1.76 vs. 4.76 ± 1.13; B levels in patients for the diagnosis and prognostication of AP in the emergency department. < 0.001 and 8.04 ± 1.76 vs. 4.76 ± 1.13; B levels in patients for the diagnosis and prognostication of AP in the emergency department. < 0.001 and 8.04 ± 1.76 vs. 4.76 ± 1.13.

Conclusion: We demonstrated that the TLR9 and NF-B pathway is activated in acute pancreatitis and increases the inflammatory process. This may help to further understand the pathogenesis of disorder, diagnosis, and clinical severity. We proposed that blockage of these inflammatory pathways may play a role in the prevention of the disease progression and development of inflammatory complications.B levels in patients for the diagnosis and prognostication of AP in the emergency department.
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http://dx.doi.org/10.1155/2020/1264714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016400PMC
February 2020
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