Sebastien M Labbé

Sebastien M Labbé

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Sebastien M Labbé

Sebastien M Labbé

Publications by authors named "Sebastien M Labbé"

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The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis.

Mol Metab 2019 Dec 4;30:184-191. Epub 2019 Oct 4.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec - Université Laval (CRIUCPQ), Québec City, Québec, Canada; Département de Médecine de l'Université Laval, Université Laval, Québec City, Québec, Canada; Centre de Recherche sur le Cancer de l'Université Laval, Université Laval, Québec City, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889588PMC
December 2019

Interscapular brown adipose tissue denervation does not promote the oxidative activity of inguinal white adipose tissue in male mice.

Am J Physiol Endocrinol Metab 2018 11 28;315(5):E815-E824. Epub 2018 Aug 28.

Institut universitaire de Cardiologie et de Pneumologie de Québec , Quebec, Quebec , Canada.

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https://www.physiology.org/doi/10.1152/ajpendo.00210.2018
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http://dx.doi.org/10.1152/ajpendo.00210.2018DOI Listing
November 2018

Loss of hepatic DEPTOR alters the metabolic transition to fasting.

Mol Metab 2017 05 17;6(5):447-458. Epub 2017 Feb 17.

Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (CRIUCPQ), Faculté de Médecine, Université Laval, 2725 Chemin Ste-Foy, Québec, Qc, G1V 4G5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2017.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404102PMC
May 2017

Loss of UCP2 impairs cold-induced non-shivering thermogenesis by promoting a shift toward glucose utilization in brown adipose tissue.

Biochimie 2017 Mar 24;134:118-126. Epub 2017 Jan 24.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, 2725 Chemin Sainte-Foy, Québec, Québec, G1V 4G5, Canada; Département de Médecine, Faculté de Médecine, Université Laval, Québec, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2017.01.006DOI Listing
March 2017

mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold.

Sci Rep 2016 11 23;6:37223. Epub 2016 Nov 23.

Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval, 2725 chemin Sainte-Foy, Québec, QC, G1V 4G5, Canada.

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http://dx.doi.org/10.1038/srep37223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120333PMC
November 2016

Metabolic activity of brown, "beige," and white adipose tissues in response to chronic adrenergic stimulation in male mice.

Am J Physiol Endocrinol Metab 2016 Jul 3;311(1):E260-8. Epub 2016 May 3.

Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, Canada; and

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http://dx.doi.org/10.1152/ajpendo.00545.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967144PMC
July 2016

DEPTOR in POMC neurons affects liver metabolism but is dispensable for the regulation of energy balance.

Am J Physiol Regul Integr Comp Physiol 2016 06 20;310(11):R1322-31. Epub 2016 Apr 20.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec, Quebec, Canada; and Département de Médecine, Faculté de Médecine, Université Laval, Québec, Québec, Canada

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http://dx.doi.org/10.1152/ajpregu.00549.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935503PMC
June 2016

Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans.

Cell Metab 2016 06 26;23(6):1200-1206. Epub 2016 May 26.

Metabolism Unit, Shriners Hospitals for Children, Galveston, TX 77555, USA; Department of Nutrition and Metabolism, Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Nutrition and Dietetics, Harokopio University of Athens, Athens 176 71, Greece; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA; Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Exercise Sciences, Rutgers University, New Brunswick, NJ 08901, USA; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ 08901, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967557PMC
June 2016

Postprandial fatty acid uptake and adipocyte remodeling in angiotensin type 2 receptor-deficient mice fed a high-fat/high-fructose diet.

Adipocyte 2016 Jan-Mar;5(1):43-52. Epub 2015 Dec 8.

Department of Medicine, Division of Endocrinology, Faculty of Medicine and Health Sciences, Université de Sherbrooke , Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.1080/21623945.2015.1115582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836487PMC
May 2016

Brown Adipose Tissue Is Linked to a Distinct Thermoregulatory Response to Mild Cold in People.

Front Physiol 2016 19;7:129. Epub 2016 Apr 19.

Metabolism Unit, Shriners Hospitals for Children-GalvestonTX, USA; Division of Rehabilitation Sciences, Department of Nutrition and Metabolism, University of Texas Medical BranchGalveston, TX, USA; Department of Nutrition and Dietetics, Harokopio University of AthensGreece; Institute for Translational Sciences, University of Texas Medical BranchGalveston, TX, USA; Sealy Center on Aging, University of Texas Medical BranchGalveston, TX, USA; Department of Internal Medicine, University of Texas Medical BranchGalveston, TX, USA; Department of Surgery, University of Texas Medical BranchGalveston, TX, USA.

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http://dx.doi.org/10.3389/fphys.2016.00129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835478PMC
May 2016

Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity.

Mol Metab 2016 Feb 8;5(2):102-112. Epub 2015 Dec 8.

Institut universitaire de cardiologie et de pneumologie de Québec, 2725 chemin Sainte-Foy, Québec, Québec, G1V 4G5, Canada; Département de Médecine, Faculté de Médecine, Université Laval, Québec, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2015.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735664PMC
February 2016

Hypothalamic control of brown adipose tissue thermogenesis.

Front Syst Neurosci 2015 3;9:150. Epub 2015 Nov 3.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Department of Medicine, Université Laval Québec, QC, Canada.

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http://dx.doi.org/10.3389/fnsys.2015.00150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630288PMC
November 2015

Selective Impairment of Glucose but Not Fatty Acid or Oxidative Metabolism in Brown Adipose Tissue of Subjects With Type 2 Diabetes.

Diabetes 2015 Jul 12;64(7):2388-97. Epub 2015 Feb 12.

Department of Medicine, Centre de Recherche du Centre hospitalier universitaire de Sherbrooke, Université de Sherbrooke, Quebec, Canada

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http://dx.doi.org/10.2337/db14-1651DOI Listing
July 2015

[(11)C]-Acetoacetate PET imaging: a potential early marker for cardiac heart failure.

Nucl Med Biol 2014 Nov-Dec;41(10):863-70. Epub 2014 Aug 13.

Sherbrooke Molecular Imaging Center of CRCHUS, Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, QC, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S09698051140046
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http://dx.doi.org/10.1016/j.nucmedbio.2014.08.006DOI Listing
June 2015

In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis.

FASEB J 2015 May 13;29(5):2046-58. Epub 2015 Feb 13.

*Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Canada; Department of Medicine, Centre de Recherche du Centre Hospitalier, and Departments of Nuclear Medicine and Radiobiology, Centre d'Imagerie Moléculaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, Canada

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http://dx.doi.org/10.1096/fj.14-266247DOI Listing
May 2015

Metabolic changes induced by the biliopancreatic diversion in diet-induced obesity in male rats: the contributions of sleeve gastrectomy and duodenal switch.

Endocrinology 2015 Apr 3;156(4):1316-29. Epub 2015 Feb 3.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Chemin Sainte-Foy, Québec, Canada G1V 4G5.

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http://dx.doi.org/10.1210/en.2014-1785DOI Listing
April 2015

Contributions of white and brown adipose tissues and skeletal muscles to acute cold-induced metabolic responses in healthy men.

J Physiol 2015 Feb 15;593(3):701-14. Epub 2014 Dec 15.

Department of Medicine, Centre de Recherche du Centre hospitalier universitaire de Sherbrooke, Université de Sherbrooke, Québec, Canada.

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http://doi.wiley.com/10.1113/jphysiol.2014.283598
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http://dx.doi.org/10.1113/jphysiol.2014.283598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324714PMC
February 2015

Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans.

Diabetes 2014 Dec 23;63(12):4089-99. Epub 2014 Jul 23.

Metabolism Unit, Shriners Hospital for Children, Galveston, TX Department of Nutrition and Metabolism, Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX

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http://dx.doi.org/10.2337/db14-0746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238005PMC
December 2014

The PVH as a site of CB1-mediated stimulation of thermogenesis by MC4R agonism in male rats.

Endocrinology 2014 Sep 20;155(9):3448-58. Epub 2014 Jun 20.

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Canada G1V 4G5.

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http://dx.doi.org/10.1210/en.2013-2092DOI Listing
September 2014

Increased brown adipose tissue oxidative capacity in cold-acclimated humans.

J Clin Endocrinol Metab 2014 Mar 13;99(3):E438-46. Epub 2014 Jan 13.

Faculty of Health Sciences (D.P.B., H.C.T., F.H.), University of Ottawa, Ottawa, Ontario, Canada K1N 6N5; Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec (S.M.L., D.R.), Université Laval, Québec City, Québec, Canada G1V 4G5; Department of Medicine (C.N., M.K., S.P., A.C.C.), Centre de Recherche Clinique Etienne-Le Bel, Université de Sherbrooke, Sherbrooke, Québec, Canada; and Department of Nuclear Medicine and Radiobiology (S.P., B.G., E.E.T.), Université de Sherbrooke, Sherbrooke, Québec, Canada J1H 5N4.

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http://dx.doi.org/10.1210/jc.2013-3901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213359PMC
March 2014

Increased myocardial uptake of dietary fatty acids linked to cardiac dysfunction in glucose-intolerant humans.

Diabetes 2012 Nov;61(11):2701-10

Department of Medicine, Division of Endocrinology, Centre de Recherche Clinique Etienne-LeBel, Université de Sherbrooke, Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.2337/db11-1805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478552PMC
November 2012

EP 80317, a selective CD36 ligand, shows cardioprotective effects against post-ischaemic myocardial damage in mice.

Cardiovasc Res 2012 Oct 10;96(1):99-108. Epub 2012 Jul 10.

Faculty of Pharmacy, Université de Montréal, PO Box 6128, Station Centre-Ville, Montréal, Québec, Canada H3C 3J7.

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http://dx.doi.org/10.1093/cvr/cvs225DOI Listing
October 2012

Control and physiological determinants of sympathetically mediated brown adipose tissue thermogenesis.

Front Endocrinol (Lausanne) 2012 27;3:36. Epub 2012 Feb 27.

Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec et Groupe interdisciplinaire de Recherche sur l'Obésité de l'Université Laval Québec, QC, Canada.

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http://dx.doi.org/10.3389/fendo.2012.00036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356074PMC
August 2012

Effect of alipogene tiparvovec (AAV1-LPL(S447X)) on postprandial chylomicron metabolism in lipoprotein lipase-deficient patients.

J Clin Endocrinol Metab 2012 May 21;97(5):1635-44. Epub 2012 Mar 21.

Department of Medicine, Division of Endocrinology, Université de Sherbrooke, Sherbrooke, Québec, Canada J1H 5N4.

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http://dx.doi.org/10.1210/jc.2011-3002DOI Listing
May 2012

Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans.

J Clin Invest 2012 Feb 24;122(2):545-52. Epub 2012 Jan 24.

Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Quebec City, Quebec, Canada.

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http://dx.doi.org/10.1172/JCI60433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266793PMC
February 2012