Sebastien Jeay

Sebastien Jeay

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Sebastien Jeay

Sebastien Jeay

Publications by authors named "Sebastien Jeay"

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The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 07 11;30(1):183. Epub 2016 Jul 11.

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http://dx.doi.org/10.1016/j.ccell.2016.06.008DOI Listing
July 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 04;29(4):574-586

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 450 Brookline Avenue, Dana 510B, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177991PMC
April 2016

Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode.

Bioorg Med Chem Lett 2015 Sep 23;25(17):3621-5. Epub 2015 Jun 23.

Novartis Institutes for BioMedical Research, WKL-136.P.12, CH-4002 Basel, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X150065
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http://dx.doi.org/10.1016/j.bmcl.2015.06.058DOI Listing
September 2015

c-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor.

J Cell Biochem 2008 Aug;104(6):2091-106

Department of Biochemistry, Boston University Medical School, 715 Albany Street, Boston, Massachusetts 02118, USA.

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http://doi.wiley.com/10.1002/jcb.21765
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http://dx.doi.org/10.1002/jcb.21765DOI Listing
August 2008

The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer.

Cancer Res 2007 Feb;67(3):1105-12

Department of Biochemistry, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3867DOI Listing
February 2007

The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells.

J Biol Chem 2004 Sep 23;279(39):40593-600. Epub 2004 Jul 23.

Division of Oral Biology, Boston University Goldman School of Dental Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1074/jbc.M406639200DOI Listing
September 2004

Reciprocal control of Forkhead box O 3a and c-Myc via the phosphatidylinositol 3-kinase pathway coordinately regulates p27Kip1 levels.

J Immunol 2004 May;172(9):5522-7

Department of Biochemistry, Boston University Medical School, Boston, MA 02118, USA.

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http://dx.doi.org/10.4049/jimmunol.172.9.5522DOI Listing
May 2004

New homologous bioassays for human lactogens show that agonism or antagonism of various analogs is a function of assay sensitivity.

Endocrine 2003 Feb-Mar;20(1-2):177-90

INSERN Unit 584, Hormone Targets, Faculty of Medicine Necker, Paris Cedex, France.

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http://dx.doi.org/10.1385/ENDO:20:1-2:177DOI Listing
December 2003

Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B.

Mol Cell Biol 2003 Apr;23(7):2251-63

Department of Biochemistry, Boston University Medical School, Boston, Massachusetts 02118, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150722PMC
http://dx.doi.org/10.1128/mcb.23.7.2251-2263.2003DOI Listing
April 2003

B-Myb repressor function is regulated by cyclin A phosphorylation and sequences within the C-terminal domain.

Oncogene 2003 Apr;22(13):2011-20

Department of Biochemistry, Boston University Medical School, MA 02118-2394, USA.

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http://dx.doi.org/10.1038/sj.onc.1206231DOI Listing
April 2003

Growth hormone can act as a cytokine controlling survival and proliferation of immune cells: new insights into signaling pathways.

Mol Cell Endocrinol 2002 Feb;188(1-2):1-7

INSERM Unité 344, Endocrinologie Moléculaire, Faculté de Médecine Necker, 75730 Paris Cedex 15, France.

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http://dx.doi.org/10.1016/s0303-7207(02)00014-xDOI Listing
February 2002