Sebastian Schneeweiss

Sebastian Schneeweiss

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Sebastian Schneeweiss

Publications by authors named "Sebastian Schneeweiss"

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Nonrandomized Real-World Evidence to Support Regulatory Decision Making: Process for a Randomized Trial Replication Project.

Clin Pharmacol Ther 2020 Apr 25;107(4):817-826. Epub 2019 Oct 25.

Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cpt.1633DOI Listing
April 2020

Trends in Clinical Characteristics and Prescribing Preferences for SGLT2 Inhibitors and GLP-1 Receptor Agonists, 2013-2018.

Diabetes Care 2020 Apr 10;43(4):921-924. Epub 2020 Feb 10.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.2337/dc19-1943DOI Listing
April 2020

Emulation Differences vs. Biases When Calibrating Real-World Evidence Findings Against Randomized Controlled Trials.

Clin Pharmacol Ther 2020 Apr 12;107(4):735-737. Epub 2020 Feb 12.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cpt.1793DOI Listing
April 2020

Application of a Graphical Depiction of Longitudinal Study Designs to Managed Care Pharmacy Research.

J Manag Care Spec Pharm 2020 Mar;26(3):268-274

Division of Pharmacoepidemiology, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.18553/jmcp.2020.26.3.268DOI Listing
March 2020

Serious infection risk in children with psoriasis on systemic treatment: a propensity score matched population-based study.

J Am Acad Dermatol 2020 Mar 3. Epub 2020 Mar 3.

Department of Dermatology, Brigham and Women's Hospital, Boston, MA; Division of Rheumatology, Department of Medicine, Brigham and Women's Hospital, Boston, MA; Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.02.065DOI Listing
March 2020

Effectiveness and Safety of Apixaban Compared With Rivaroxaban for Patients With Atrial Fibrillation in Routine Practice: A Cohort Study.

Ann Intern Med 2020 Mar 10. Epub 2020 Mar 10.

Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts (S.S., K.F.H., K.J.L., J.J.G.).

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http://dx.doi.org/10.7326/M19-2522DOI Listing
March 2020

Fournier's gangrene in patients with type 2 diabetes using second-line antidiabetic medications.

Diabetes Obes Metab 2020 Feb 13;22(2):267-271. Epub 2019 Oct 13.

Pharmacy Strategy and Clinical Integration, Horizon Healthcare Services Inc., Newark, New Jersey.

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http://dx.doi.org/10.1111/dom.13886DOI Listing
February 2020

External Validation of an Algorithm to Identify Patients with High Data-Completeness in Electronic Health Records for Comparative Effectiveness Research.

Clin Epidemiol 2020 4;12:133-141. Epub 2020 Feb 4.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.2147/CLEP.S232540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007793PMC
February 2020

When Randomized Clinical Trials and Real-World Evidence Say the Same: Tocilizumab and Its Cardiovascular Safety.

Arthritis Rheumatol 2020 01;72(1):4-6

Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/art.41092DOI Listing
January 2020

Comparison of Machine Learning Methods With Traditional Models for Use of Administrative Claims With Electronic Medical Records to Predict Heart Failure Outcomes.

JAMA Netw Open 2020 Jan 3;3(1):e1918962. Epub 2020 Jan 3.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.18962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991258PMC
January 2020

Risk of Inflammatory Arthritis After a New Diagnosis of Hidradenitis Suppurativa.

JAMA Dermatol 2020 Jan 22. Epub 2020 Jan 22.

Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamadermatol.2019.4590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990727PMC
January 2020

Improving measurement of binary covariates in claims data: A simulation study.

Pharmacoepidemiol Drug Saf 2020 Jan 23. Epub 2020 Jan 23.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.

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http://dx.doi.org/10.1002/pds.4961DOI Listing
January 2020

Using Real-World Data to Predict Findings of an Ongoing Phase IV Cardiovascular Outcome Trial: Cardiovascular Safety of Linagliptin Versus Glimepiride.

Diabetes Care 2019 Dec 25;42(12):2204-2210. Epub 2019 Jun 25.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.2337/dc19-0069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868466PMC
December 2019

Actionable Real-World Evidence to Improve Health Outcomes and Reduce Medical Spending Among Risk-Stratified Patients with Diabetes.

J Manag Care Spec Pharm 2019 Dec;25(12):1442-1452

Department of Pharmacy Practice and Administration, Pharmacy Strategy and Clinical Integration, Horizon Blue Cross Blue Shield of New Jersey, Newark, and Rutgers State University of New Jersey School of Pharmacy, Piscataway.

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http://dx.doi.org/10.18553/jmcp.2019.25.12.1442DOI Listing
December 2019

Sodium-Glucose Cotransporter-2 Inhibitors and Urinary Tract Infections.

Ann Intern Med 2019 Dec;171(12):944-945

Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts (C.V.D., S.S., D.K., M.F., E.P.).

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http://dx.doi.org/10.7326/L19-0671DOI Listing
December 2019

Using nationally representative survey data for external adjustment of unmeasured confounders: An example using the NHANES data.

Pharmacoepidemiol Drug Saf 2019 Dec 20. Epub 2019 Dec 20.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/pds.4946DOI Listing
December 2019

Safety and Effectiveness of Dabigatran and Other Direct Oral Anticoagulants Compared With Warfarin in Patients With Atrial Fibrillation.

Clin Pharmacol Ther 2019 Dec 23. Epub 2019 Dec 23.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cpt.1753DOI Listing
December 2019

Multimodal Analysis of FDA Drug Safety Communications: Lessons from Zolpidem.

Drug Saf 2019 11;42(11):1287-1295

US Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA.

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http://dx.doi.org/10.1007/s40264-019-00849-8DOI Listing
November 2019

Non-Vitamin K Antagonist Oral Anticoagulants and Angioedema: A Cohort and Case-Crossover Study.

Drug Saf 2019 11;42(11):1355-1363

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1620 Tremont St., Suite 3030, Boston, MA, 02120, USA.

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http://link.springer.com/10.1007/s40264-019-00852-z
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http://dx.doi.org/10.1007/s40264-019-00852-zDOI Listing
November 2019

Response to van Domelen and Bandeen-Roche's Commentary.

Am J Epidemiol 2019 Nov 1. Epub 2019 Nov 1.

Division of Pharmacoepidemiology and Pharmacoeconomics, Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1093/aje/kwz250DOI Listing
November 2019

Risk of malignancy associated with use of tocilizumab versus other biologics in patients with rheumatoid arthritis: A multi-database cohort study.

Semin Arthritis Rheum 2019 10 9;49(2):222-228. Epub 2019 Mar 9.

Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, 1620 Tremont Street, Suite 3030, Boston MA 02120, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00490172183058
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http://dx.doi.org/10.1016/j.semarthrit.2019.03.002DOI Listing
October 2019

Comparison of alternative approaches to trim subjects in the tails of the propensity score distribution.

Pharmacoepidemiol Drug Saf 2019 10 5;28(10):1290-1298. Epub 2019 Aug 5.

Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1002/pds.4846DOI Listing
October 2019

Desmopressin and the risk of hyponatremia: A population-based cohort study.

PLoS Med 2019 10 21;16(10):e1002930. Epub 2019 Oct 21.

Division of Pharmacoepidemiology and Pharmacoeconomics, Program On Regulation, Therapeutics, And Law (PORTAL), Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802819PMC
October 2019

Association of Sodium-Glucose Cotransporter 2 Inhibitor Treatment With Risk of Hospitalization for Fournier Gangrene Among Men.

JAMA Intern Med 2019 Sep 3. Epub 2019 Sep 3.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamainternmed.2019.2813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724526PMC
September 2019

Discussion of Schuemie et al: "A plea to stop using the case-control design in retrospective database studies".

Stat Med 2019 09;38(22):4209-4212

Centre for Clinical Epidemiology, Lady Davis Research Institute, Jewish General Hospital and Department of Epidemiology and Biostatistics, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1002/sim.8320DOI Listing
September 2019

Measuring Frailty in Administrative Claims Data: Comparative Performance of Four Claims-Based Frailty Measures in the United States Medicare Data.

J Gerontol A Biol Sci Med Sci 2019 Sep 30. Epub 2019 Sep 30.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1093/gerona/glz224DOI Listing
September 2019

Cardiovascular safety of linagliptin compared with other oral glucose-lowering agents in patients with type 2 diabetes: A sequential monitoring programme in routine care.

Diabetes Obes Metab 2019 08 1;21(8):1824-1836. Epub 2019 May 1.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1111/dom.13735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785989PMC
August 2019

Validation of a Claims-Based Frailty Index Against Physical Performance and Adverse Health Outcomes in the Health and Retirement Study.

J Gerontol A Biol Sci Med Sci 2019 Jul;74(8):1271-1276

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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https://academic.oup.com/biomedgerontology/advance-article/d
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http://dx.doi.org/10.1093/gerona/gly197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625579PMC
July 2019

A Case-Crossover-Based Screening Approach to Identifying Clinically Relevant Drug-Drug Interactions in Electronic Healthcare Data.

Clin Pharmacol Ther 2019 07 18;106(1):238-244. Epub 2019 Mar 18.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://doi.wiley.com/10.1002/cpt.1376
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http://dx.doi.org/10.1002/cpt.1376DOI Listing
July 2019

Real-World Evidence of Treatment Effects: The Useful and the Misleading.

Clin Pharmacol Ther 2019 07 3;106(1):43-44. Epub 2019 Apr 3.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cpt.1405
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http://dx.doi.org/10.1002/cpt.1405DOI Listing
July 2019

Evaluating utilization patterns of oral anticoagulants in routine care.

J Thromb Haemost 2019 07 29;17(7):1033-1043. Epub 2019 May 29.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1111/jth.14467DOI Listing
July 2019

Fracture Risk After Initiation of Use of Canagliflozin.

Ann Intern Med 2019 07;171(1):80

Brigham and Women's Hospital, Boston, Massachusetts (M.F., S.C.K., S.S., D.K., E.P.).

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http://dx.doi.org/10.7326/L19-0320DOI Listing
July 2019

Controlling Confounding in a Study of Oral Anticoagulants: Comparing Disease Risk Scores Developed Using Different Follow-Up Approaches.

EGEMS (Wash DC) 2019 Jul 15;7(1):27. Epub 2019 Jul 15.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, US.

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http://dx.doi.org/10.5334/egems.254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640656PMC
July 2019

Sodium-Glucose Cotransporter-2 Inhibitors and the Risk for Severe Urinary Tract Infections: A Population-Based Cohort Study.

Ann Intern Med 2019 Jul 30. Epub 2019 Jul 30.

Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts (C.V.D., S.S., D.K., M.F., A.T., E.P.).

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http://dx.doi.org/10.7326/M18-3136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989379PMC
July 2019

Evaluation of Socioeconomic Status Indicators for Confounding Adjustment in Observational Studies of Medication Use.

Clin Pharmacol Ther 2019 06 25;105(6):1513-1521. Epub 2019 Feb 25.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://doi.wiley.com/10.1002/cpt.1348
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http://dx.doi.org/10.1002/cpt.1348DOI Listing
June 2019

Empagliflozin and the Risk of Heart Failure Hospitalization in Routine Clinical Care.

Circulation 2019 06 8;139(25):2822-2830. Epub 2019 Apr 8.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (E.P., A.P., J.M.F., M.N., L.G.B., A.J.S.O., M.K., S.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.039177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594384PMC
June 2019

Cardiovascular Outcomes of Calcium-Free vs Calcium-Based Phosphate Binders in Patients 65 Years or Older With End-stage Renal Disease Requiring Hemodialysis.

JAMA Intern Med 2019 Jun;179(6):741-749

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamainternmed.2019.0045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503544PMC
June 2019

La déclaration RECORD-PE (Reporting of Studies Conducted Using Observational Routinely Collected Health Data Statement for Pharmacoepdemiology) : directives pour la communication des études realisées à partir de données de santé observationelles collectées en routine en pharmacoépidémiologie.

CMAJ 2019 06;191(25):E689-E708

Faculty of Epidemiology and Population Health (Langan, Wing, Smeeth), London School of Hygiene and Tropical Medicine, Londres, Royaume-Uni ; Département d'épidémiologie clinique (Schmidt, Ehrenstein, Petersen, Sørensen), université d'Aarhus, Aarhus, Danemark ; Institut de recherche de l'Hôpital d'Ottawa (Nicholls, Moher) ; École d'épidémiologie et de santé publique (Nicholls), Université d'Ottawa, Ottawa, Ont. ; Département d'épidémiologie, de bio-statistique et de santé au travail (Filion), Université McGill ; Centre d'épidémiologie clinique (Filion), Institut Lady Davis, Hôpital général juif, Montréal, Qué. ; Division of Pharmacoepidemiology and Clinical Pharmacology (Klungel), Utrecht Institute for Pharmaceutical Sciences, université d'Utrecht, Utrecht, Pays-Bas ; Department of Primary Care and Population Health (Petersen), University College London, Londres, Royaume-Uni ; Arthritis Research UK Centre for Epidemiology (Dixon), Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, Royaume-Uni ; ICES (Guttmann, Benchimol) ; Department of Paediatrics (Guttmann), The Hospital for Sick Children, université de Toronto, Toronto, Ont. ; Population, Policy and Practice Programme (Harron), Great Ormond Street Institute of Child Health, University College London, Londres, Royaume-Uni ; Basel Institute for Clinical Epidemiology and Biostatistics (Hemkens), Department of Clinical Research, University Hospital of Basel, université de Basel, Basel, Suisse ; Division of Pharmacoepidemiology and Pharmacoeconomics (Schneeweiss, Wang), Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass. ; Julius Global Health (Sturkenboom), University Medical Center Utrecht, Utrecht, Pays-Bas ; Cochrane Suisse (von Elm), Institut de médecine sociale et préventive, Université de Lausanne, Lausanne, Suisse ; Département de pédiatrie et École d'épidémiologie et de santé publique (Benchimol), Université d'Ottawa ; Institut de recherche du Centre hospitalier pour enfants de l'est de l'Ontario (Benchimol), Ottawa, Ont.

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http://dx.doi.org/10.1503/cmaj.190347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592814PMC
June 2019

Using Real-World Data to Extrapolate Evidence From Randomized Controlled Trials.

Clin Pharmacol Ther 2019 05 24;105(5):1156-1163. Epub 2018 Sep 24.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cpt.1210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438758PMC
May 2019

Quantifying bias reduction with fixed-duration versus all-available covariate assessment periods.

Pharmacoepidemiol Drug Saf 2019 05 20;28(5):665-670. Epub 2019 Feb 20.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/pds.4729DOI Listing
May 2019

General Population vs. Patient Preferences in Anticoagulant Therapy: A Discrete Choice Experiment.

Patient 2019 04;12(2):235-246

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s40271-018-0329-1DOI Listing
April 2019

Claims Data Studies of Direct Oral Anticoagulants Can Achieve Balance in Important Clinical Parameters Only Observable in Electronic Health Records.

Clin Pharmacol Ther 2019 04 11;105(4):979-993. Epub 2018 Nov 11.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cpt.1256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422763PMC
April 2019

Evaluating the Use of Nonrandomized Real-World Data Analyses for Regulatory Decision Making.

Clin Pharmacol Ther 2019 04 25;105(4):867-877. Epub 2019 Feb 25.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cpt.1351DOI Listing
April 2019

The Case-Crossover Design for Drug-Drug Interactions: Considerations for Implementation.

Epidemiology 2019 03;30(2):204-211

From the Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/EDE.0000000000000944DOI Listing
March 2019

Theory meets practice: a commentary on VanderWeele's 'principles of confounder selection'.

Eur J Epidemiol 2019 03 6;34(3):221-222. Epub 2019 Mar 6.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s10654-019-00495-5DOI Listing
March 2019

Graphical Depiction of Longitudinal Study Designs in Health Care Databases.

Ann Intern Med 2019 03 12;170(6):398-406. Epub 2019 Mar 12.

Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts (S.S., S.V.W.).

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http://dx.doi.org/10.7326/M18-3079DOI Listing
March 2019

Psychosis with Methylphenidate or Amphetamine in Patients with ADHD.

N Engl J Med 2019 03;380(12):1128-1138

From the Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston (L.V.M., S.S.); the Division of Psychotic Disorders, McLean Hospital, Belmont, MA (L.V.M., D.O.); and the Department of Health Care Policy (J.H.), Harvard Medical School (L.V.M., D.O., J.H., R.H.P., S.S.), the Mongan Institute Health Policy Center (J.H.) and the Center for Quantitative Health, Department of Psychiatry (R.H.P.), Massachusetts General Hospital, and Partners Research Computing, Partners HealthCare System (V.M.C.) - all in Boston.

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http://dx.doi.org/10.1056/NEJMoa1813751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543546PMC
March 2019

Comparative risk of genital infections associated with sodium-glucose co-transporter-2 inhibitors.

Diabetes Obes Metab 2019 02 11;21(2):434-438. Epub 2018 Oct 11.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://doi.wiley.com/10.1111/dom.13531
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http://dx.doi.org/10.1111/dom.13531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329650PMC
February 2019

Fracture Risk After Initiation of Use of Canagliflozin: A Cohort Study.

Ann Intern Med 2019 02 1;170(3):155-163. Epub 2019 Jan 1.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts (S.C.K., S.S., D.K., E.P.).

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http://dx.doi.org/10.7326/M18-0567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602870PMC
February 2019

Sequential Monitoring of the Comparative Effectiveness and Safety of Dabigatran in Routine Care.

Circ Cardiovasc Qual Outcomes 2019 02;12(2):e005173

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.S., C.G., J.M.F., M.K., K.F.H.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.118.005173DOI Listing
February 2019

No difference in cardiovascular risk of tocilizumab versus abatacept for rheumatoid arthritis: A multi-database cohort study.

Semin Arthritis Rheum 2018 12 22;48(3):399-405. Epub 2018 Mar 22.

Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120.

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http://dx.doi.org/10.1016/j.semarthrit.2018.03.012DOI Listing
December 2018

Comparative effectiveness and safety of antiplatelet drugs in patients with diabetes mellitus and acute coronary syndrome.

Pharmacoepidemiol Drug Saf 2018 Dec 31;27(12):1361-1370. Epub 2018 Oct 31.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/pds.4668DOI Listing
December 2018

Development and Preliminary Validation of a Medicare Claims-Based Model to Predict Left Ventricular Ejection Fraction Class in Patients With Heart Failure.

Circ Cardiovasc Qual Outcomes 2018 12;11(12):e004700

Department of Medicine, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (R.J.D., K.J.L., E.P., J.B., M.L., R.L., S.V.W., S.S.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.118.004700DOI Listing
December 2018

Simulation for Predicting Effectiveness and Safety of New Cardiovascular Drugs in Routine Care Populations.

Clin Pharmacol Ther 2018 11 8;104(5):1008-1015. Epub 2018 Mar 8.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cpt.1045DOI Listing
November 2018

Erratum: High-dimensional Propensity Score Adjustment in Studies of Treatment Effects Using Health Care Claims Data.

Epidemiology 2018 11;29(6):e63-e64

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/EDE.0000000000000886DOI Listing
November 2018

Using Previous Medication Adherence to Predict Future Adherence.

J Manag Care Spec Pharm 2018 Nov;24(11):1146-1155

2 Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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https://www.jmcp.org/doi/10.18553/jmcp.2018.24.11.1146
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http://dx.doi.org/10.18553/jmcp.2018.24.11.1146DOI Listing
November 2018

Relative Performance of Propensity Score Matching Strategies for Subgroup Analyses.

Am J Epidemiol 2018 08;187(8):1799-1807

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1093/aje/kwy049DOI Listing
August 2018

Association of Medicare's Bundled Payment Reform With Changes in Use of Vitamin D Among Patients Receiving Maintenance Hemodialysis: An Interrupted Time-Series Analysis.

Am J Kidney Dis 2018 08 8;72(2):178-187. Epub 2018 Jun 8.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2018.03.027DOI Listing
August 2018

Defining Exposure in Observational Studies Comparing Outcomes of Treatment Discontinuation.

Circ Cardiovasc Qual Outcomes 2018 07;11(7):e004684

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, MA (A.A.K., R.J.G., S.S., N.K.C., A.Y.T., J.J.G.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.118.004684DOI Listing
July 2018

Automated data-adaptive analytics for electronic healthcare data to study causal treatment effects.

Clin Epidemiol 2018 6;10:771-788. Epub 2018 Jul 6.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital,

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http://dx.doi.org/10.2147/CLEP.S166545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039060PMC
July 2018

Measuring Frailty in Medicare Data: Development and Validation of a Claims-Based Frailty Index.

J Gerontol A Biol Sci Med Sci 2018 06;73(7):980-987

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1093/gerona/glx229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001883PMC
June 2018

Hypothesis-free screening of large administrative databases for unsuspected drug-outcome associations.

Eur J Epidemiol 2018 Jun 31;33(6):545-555. Epub 2018 Mar 31.

Clinical Pharmacology and Pharmacy, Department of Public Health, University of Southern Denmark, JB Winsløwsvej 19, 2, 5000, Odense C, Denmark.

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http://dx.doi.org/10.1007/s10654-018-0386-8DOI Listing
June 2018

Comparing Approaches to Measure Frailty in Medicare Data: Deficit-Accumulation Frailty Index Versus Phenotypic Frailty.

J Gerontol A Biol Sci Med Sci 2018 06;73(7):989-990

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1093/gerona/gly054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279157PMC
June 2018

Removal of ineligible outcome cases reduces confounding.

Clin Epidemiol 2018 21;10:575-579. Epub 2018 May 21.

Analysis Group, Inc., Boston, MA, USA.

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http://dx.doi.org/10.2147/CLEP.S160482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973633PMC
May 2018

The Ad-Hoc Uncertainty Principle of Patient Privacy.

AMIA Jt Summits Transl Sci Proc 2018 18;2017:132-138. Epub 2018 May 18.

Harvard Medical School.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961824PMC
May 2018

Real-World Data Analytics Fit for Regulatory Decision-Making.

Am J Law Med 2018 May;44(2-3):197-217

The authors are from the Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Dr. Schneeweiss's research that contributed to this work is funded by grants and contracts from the Patient Center Outcomes Research Institute, the National Institutes of Health, the U.S. Food & Drug Administration. Disclosures - Dr. Schneeweiss is a principal investigator of research contracts from Genentech, Inc. and Boehringer Ingelheim to Brigham and Women's Hospital from which he receives a salary. He is a consultant to WHISCON, LLC and Aetion, Inc., of which he holds equity. The current paper is closely adapted from the prior work of the authors.

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http://dx.doi.org/10.1177/0098858818789429DOI Listing
May 2018

Claims-based studies of oral glucose-lowering medications can achieve balance in critical clinical variables only observed in electronic health records.

Diabetes Obes Metab 2018 04 12;20(4):974-984. Epub 2018 Jan 12.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1111/dom.13184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207375PMC
April 2018

Generalized boosted modeling to identify subgroups where effect of dabigatran versus warfarin may differ: An observational cohort study of patients with atrial fibrillation.

Pharmacoepidemiol Drug Saf 2018 04 30;27(4):383-390. Epub 2018 Jan 30.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/pds.4395DOI Listing
April 2018

Real-world effects of medications for chronic obstructive pulmonary disease: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results.

BMJ Open 2018 03 25;8(3):e019475. Epub 2018 Mar 25.

Department of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1136/bmjopen-2017-019475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875594PMC
March 2018

Cardiovascular outcomes associated with canagliflozin versus other non-gliflozin antidiabetic drugs: population based cohort study.

BMJ 2018 02 6;360:k119. Epub 2018 Feb 6.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 1620 Tremont St, Suite 3030, Boston, MA 02120, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799855PMC
http://dx.doi.org/10.1136/bmj.k119DOI Listing
February 2018

Use of Health Care Databases to Support Supplemental Indications of Approved Medications.

JAMA Intern Med 2018 01;178(1):55-63

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamainternmed.2017.3919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833514PMC
January 2018

"Impact of drug-reimbursement policies on prescribing: A case-study of a newly marketed long-acting injectable antipsychotic among relapsed schizophrenia patients".

Pharmacoepidemiol Drug Saf 2018 01 23;27(1):95-104. Epub 2017 Nov 23.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/pds.4354DOI Listing
January 2018

Preferential prescribing and utilization trends of diabetes medications among patients with renal impairment: Emerging role of linagliptin and other dipeptidyl peptidase 4 inhibitors.

Endocrinol Diabetes Metab 2018 Jan 27;1(1):e00005. Epub 2017 Nov 27.

Division of Pharmacoepidemiology and Pharmacoeconomics Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA USA.

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http://dx.doi.org/10.1002/edm2.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360917PMC
January 2018

Study protocol for the dabigatran, apixaban, rivaroxaban, edoxaban, warfarin comparative effectiveness research study.

J Comp Eff Res 2018 01 21;7(1):57-66. Epub 2017 Dec 21.

Division of Pharmacoepidemiology & Pharmacoeconomics, Department of Medicine, Brigham & Women's Hospital & Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA.

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https://www.futuremedicine.com/doi/10.2217/cer-2017-0053
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http://dx.doi.org/10.2217/cer-2017-0053DOI Listing
January 2018

Medication Synchronization Programs Improve Adherence To Cardiovascular Medications And Health Care Use.

Health Aff (Millwood) 2018 01;37(1):125-133

Niteesh K. Choudhry is a professor of medicine at Harvard Medical School, an associate physician in the Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, and executive director of the Center for Healthcare Delivery Sciences, Brigham and Women's Hospital.

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http://dx.doi.org/10.1377/hlthaff.2017.0881DOI Listing
January 2018

A review of the performance of different methods for propensity score matched subgroup analyses and a summary of their application in peer-reviewed research studies.

Pharmacoepidemiol Drug Saf 2017 Dec 6;26(12):1507-1512. Epub 2017 Oct 6.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/pds.4328DOI Listing
December 2017

Synergies From Integrating Randomized Controlled Trials and Real-World Data Analyses.

Clin Pharmacol Ther 2017 Dec 16;102(6):914-916. Epub 2017 Oct 16.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cpt.873DOI Listing
December 2017

Prediction Score for Anticoagulation Control Quality Among Older Adults.

J Am Heart Assoc 2017 Oct 5;6(10). Epub 2017 Oct 5.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/JAHA.117.006814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721874PMC
October 2017

Variation in adherence to medications across the healthcare system in two comparative effectiveness research cohorts.

J Comp Eff Res 2017 Oct 17;6(7):613-625. Epub 2017 Oct 17.

Division of Pharmacoepidemiology & Pharmacoeconomics, Department of Medicine, Brigham & Women's Hospital & Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.2217/cer-2016-0095DOI Listing
October 2017