Sebastian M Waszak

Sebastian M Waszak

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Sebastian M Waszak

Sebastian M Waszak

Publications by authors named "Sebastian M Waszak"

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26Publications

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Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.

Cancer Cell 2018 12;34(6):996-1011.e8

Finsen Laboratory, Rigshospitalet, DK-2200, Copenhagen, Denmark; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, DK-2200, Copenhagen, Denmark; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69120 Heidelberg, Germany; Charité Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.10.016DOI Listing
December 2018

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Lancet Oncol 2018 06 9;19(6):785-798. Epub 2018 May 9.

Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Hopp Children's Cancer Center at the NCT Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183024
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http://dx.doi.org/10.1016/S1470-2045(18)30242-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984248PMC
June 2018

The whole-genome landscape of medulloblastoma subtypes.

Nature 2017 07;547(7663):311-317

Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature22973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905700PMC
July 2017

No correlation between NF1 mutation position and risk of optic pathway glioma in 77 unrelated NF1 patients.

Hum Genet 2016 May 11;135(5):469-475. Epub 2016 Mar 11.

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00439-016-1646-xDOI Listing
May 2016

Population Variation and Genetic Control of Modular Chromatin Architecture in Humans.

Cell 2015 Aug 20;162(5):1039-50. Epub 2015 Aug 20.

Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva 1211, Switzerland; Institute of Genetics and Genomics in Geneva, University of Geneva, Geneva 1211, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.08.001DOI Listing
August 2015

Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network.

Elife 2014 Aug 27;3:e03346. Epub 2014 Aug 27.

Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.

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http://dx.doi.org/10.7554/eLife.03346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359378PMC
August 2014

Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data.

Bioinformatics 2014 Jan 18;30(2):165-71. Epub 2013 Nov 18.

Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland, Department of Genetic Medicine and Development, University of Geneva Medical School, Institute of Genetics and Genomics in Geneva, University of Geneva, 1211, Geneva, Switzerland and Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, 1011, Lausanne, Switzerland.

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http://dx.doi.org/10.1093/bioinformatics/btt667DOI Listing
January 2014

Rounding up natural gene expression variation during development.

Dev Cell 2013 Dec;27(6):601-3

Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, Switzerland; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2013.12.007DOI Listing
December 2013

A yeast one-hybrid and microfluidics-based pipeline to map mammalian gene regulatory networks.

Mol Syst Biol 2013 Aug 6;9:682. Epub 2013 Aug 6.

Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/msb.2013.38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779800PMC
August 2013

Genomic variation and its impact on gene expression in Drosophila melanogaster.

PLoS Genet 2012 15;8(11):e1003055. Epub 2012 Nov 15.

Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.1371/journal.pgen.1003055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499359PMC
May 2013

Personal receptor repertoires: olfaction as a model.

BMC Genomics 2012 Aug 21;13:414. Epub 2012 Aug 21.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1186/1471-2164-13-414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462693PMC
August 2012

Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPβ and KAISO.

Mol Cell 2012 May 19;46(3):335-50. Epub 2012 Apr 19.

Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.molcel.2012.03.017DOI Listing
May 2012

Relating CNVs to transcriptome data at fine resolution: assessment of the effect of variant size, type, and overlap with functional regions.

Genome Res 2011 Dec 23;21(12):2004-13. Epub 2011 Aug 23.

European Molecular Biology Laboratory (EMBL), Genome Biology Research Unit, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1101/gr.122614.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227091PMC
December 2011