Sebastian J Arnold

Sebastian J Arnold

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Sebastian J Arnold

Sebastian J Arnold

Publications by authors named "Sebastian J Arnold"

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39Publications

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Lack of Type 2 Innate Lymphoid Cells Promotes a Type I-Driven Enhanced Immune Response in Contact Hypersensitivity.

J Invest Dermatol 2018 09 9;138(9):1962-1972. Epub 2018 Mar 9.

Allergy Research Group, Department of Dermatology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Experimental Dermatology and Allergy Research Group, Department of Dermatology and Allergology, University Medical Center Giessen and Marburg, Campus Giessen, Justus Liebig University, Giessen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117454PMC
September 2018

CXCL12-mediated feedback from granule neurons regulates generation and positioning of new neurons in the dentate gyrus.

Glia 2018 08 14;66(8):1566-1576. Epub 2018 Mar 14.

Institute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Jena, 07747, Germany.

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http://dx.doi.org/10.1002/glia.23324DOI Listing
August 2018

The E2A splice variant E47 regulates the differentiation of projection neurons via p57(KIP2) during cortical development.

Development 2017 11 22;144(21):3917-3931. Epub 2017 Sep 22.

Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg 79104, Germany

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http://dx.doi.org/10.1242/dev.145698DOI Listing
November 2017

Reprogramming to pluripotency does not require transition through a primitive streak-like state.

Sci Rep 2017 11 29;7(1):16543. Epub 2017 Nov 29.

Institute of Neuroanatomy & Developmental Biology (INDB), Eberhard Karls University Tuebingen, Oesterbergstr. 3, 72074, Tuebingen, Germany.

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http://dx.doi.org/10.1038/s41598-017-15187-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707390PMC
November 2017

A dual-fluorescence reporter in the Eomes locus for live imaging and medium-term lineage tracing.

Genesis 2017 08 14;55(8). Epub 2017 Jul 14.

Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/dvg.23043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568967PMC
August 2017

Engineering kidney cells: reprogramming and directed differentiation to renal tissues.

Cell Tissue Res 2017 07 30;369(1):185-197. Epub 2017 May 30.

Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/s00441-017-2629-5DOI Listing
July 2017

Efficient genome editing of differentiated renal epithelial cells.

Pflugers Arch 2017 02 16;469(2):303-311. Epub 2016 Dec 16.

Renal Division, Department of Medicine, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/s00424-016-1924-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222933PMC
February 2017

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.

Nat Cell Biol 2016 Dec 7;18(12):1269-1280. Epub 2016 Nov 7.

Department of Medicine, Renal Division, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.

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http://dx.doi.org/10.1038/ncb3437DOI Listing
December 2016

Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis.

Nat Commun 2016 12 16;7:13708. Epub 2016 Dec 16.

Inflammation Research, Institute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland.

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http://dx.doi.org/10.1038/ncomms13708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172358PMC
December 2016

Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity.

Cell Rep 2016 06 16;16(1):92-105. Epub 2016 Jun 16.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA; Department of Neurological Surgery, University of Washington School of Medicine, Seattle, WA 98104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.05.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927342PMC
June 2016

Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells.

Nat Commun 2014 ;5:3174

1] Urologische Klinik und Zentrale Klinische Forschung, Klinikum der Universität Freiburg, Breisacher Strasse 66, 79106 Freiburg, Germany [2] BIOSS Centre of Biological Signalling Studies, Albert-Ludwigs-University, Freiburg, Germany.

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http://dx.doi.org/10.1038/ncomms4174DOI Listing
March 2016

A Resource for the Transcriptional Signature of Bona Fide Trophoblast Stem Cells and Analysis of Their Embryonic Persistence.

Stem Cells Int 2015 14;2015:218518. Epub 2015 Dec 14.

Renal Department, Centre for Clinical Research, University Medical Centre, Breisacher Strasse 66, 79106 Freiburg, Germany; Institute of Experimental and Clinical Pharmacology and Toxicology, University of Freiburg, Freiburg, Germany; BIOSS, Centre for Biological Signalling Studies, Albert Ludwigs University, Freiburg, Germany.

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http://dx.doi.org/10.1155/2015/218518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691490PMC
January 2016

Eomesodermin Expression in CD4+ T Cells Restricts Peripheral Foxp3 Induction.

J Immunol 2015 Nov 9;195(10):4742-52. Epub 2015 Oct 9.

Max-Planck-Institute of Immunobiology and Epigenetics, D-79108 Freiburg, Germany; Center for Chronic Immunodeficiency, University Medical Center Freiburg and University of Freiburg, D-79106 Freiburg, Germany;

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http://dx.doi.org/10.4049/jimmunol.1501159DOI Listing
November 2015

Cortical and Clonal Contribution of Tbr2 Expressing Progenitors in the Developing Mouse Brain.

Cereb Cortex 2015 Oct 13;25(10):3290-302. Epub 2014 Jun 13.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/cercor/bhu125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585488PMC
October 2015

Intermediate Progenitors Facilitate Intracortical Progression of Thalamocortical Axons and Interneurons through CXCL12 Chemokine Signaling.

J Neurosci 2015 Sep;35(38):13053-63

Institute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, 07747 Jena, Germany,

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http://dx.doi.org/10.1523/JNEUROSCI.1488-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605439PMC
September 2015

Ablation of hippocampal neurogenesis in mice impairs the response to stress during the dark cycle.

Nat Commun 2015 Sep 29;6:8373. Epub 2015 Sep 29.

Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Tao-Yuan 33302, Taiwan.

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http://dx.doi.org/10.1038/ncomms9373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598562PMC
September 2015

Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells.

EMBO J 2015 Apr 23;34(8):1078-89. Epub 2015 Feb 23.

University Medical Centre, Renal Department, Centre for Clinical Research, Freiburg, Germany BIOSS Centre of Biological Signalling Studies, Albert-Ludwigs-University, Freiburg, Germany

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http://dx.doi.org/10.15252/embj.201490805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406653PMC
April 2015

Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo.

Nat Commun 2014 Sep 15;5:4931. Epub 2014 Sep 15.

1] Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, D-79104 Freiburg, Germany [2] BIOSS Centre of Biological Signalling Studies, Albert-Ludwigs-University, D-79104 Freiburg, Germany.

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http://dx.doi.org/10.1038/ncomms5931DOI Listing
September 2014

The transcription factor T-bet is induced by IL-15 and thymic agonist selection and controls CD8αα(+) intraepithelial lymphocyte development.

Immunity 2014 Aug;41(2):230-43

Institute of Medical Microbiology and Hygiene, University of Freiburg Medical Center, 79104 Freiburg, Germany; Department of Internal Medicine IV, University of Freiburg Medical Center, 79106 Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.06.018DOI Listing
August 2014

Generation and characterization of a tamoxifen-inducible Eomes(CreER) mouse line.

Genesis 2013 Oct 30;51(10):725-33. Epub 2013 Aug 30.

University Medical Centre, Renal Department, Centre for Clinical Research, Freiburg, Germany.

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http://dx.doi.org/10.1002/dvg.22417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112203PMC
October 2013

The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation.

Nat Cell Biol 2011 Aug 7;13(9):1084-91. Epub 2011 Aug 7.

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.

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http://dx.doi.org/10.1038/ncb2304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531310PMC
August 2011

Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation.

Mol Cell Biol 2009 Nov 8;29(21):5813-27. Epub 2009 Sep 8.

University of Oxford, Sir William Dunn School of Pathology, South Parks Road, Oxford OX1 3RE, United Kingdom.

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http://dx.doi.org/10.1128/MCB.00670-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772737PMC
November 2009

Generation and analysis of a mouse line harboring GFP in the Eomes/Tbr2 locus.

Genesis 2009 Nov;47(11):775-81

Renal Division, University Hospital Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/dvg.20562DOI Listing
November 2009

Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo.

Nat Rev Mol Cell Biol 2009 Feb 8;10(2):91-103. Epub 2009 Jan 8.

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.

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http://dx.doi.org/10.1038/nrm2618DOI Listing
February 2009

Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse.

Development 2008 Feb 2;135(3):501-11. Epub 2008 Jan 2.

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.

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http://dx.doi.org/10.1242/dev.014357DOI Listing
February 2008

Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo.

Dev Biol 2006 Aug;296(1):104-18

Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1016/j.ydbio.2006.04.442DOI Listing
August 2006

Direct binding of Lef1 to sites in the boz promoter may mediate pre-midblastula-transition activation of boz expression.

Dev Dyn 2003 Nov;228(3):424-32

Developmental Biology, Institute Biology 1, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/dvdy.10408DOI Listing
November 2003