Publications by authors named "Sebastian Clauss"

40Publications

Isolation of High Quality Murine Atrial and Ventricular Myocytes for Simultaneous Measurements of Ca2+ Transients and L-Type Calcium Current.

J Vis Exp 2020 Nov 3(165). Epub 2020 Nov 3.

Institute of Pharmacology and Toxicology, University Medical Center Göttingen; Partner Site Göttingen, DZHK (German Centre for Cardiovascular Research); Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen.

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http://dx.doi.org/10.3791/61964DOI Listing
November 2020

Precise Correction of Heterozygous SHOX2 Mutations in hiPSCs Derived from Patients with Atrial Fibrillation via Genome Editing and Sib Selection.

Stem Cell Reports 2020 10 24;15(4):999-1013. Epub 2020 Sep 24.

Department of Human Molecular Genetics, Institute of Human Genetics, University of Heidelberg, 69120 Heidelberg, Baden-Wuerttemberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2020.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7562944PMC
October 2020

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls.

Authors:
Roddy Walsh Najim Lahrouchi Rafik Tadros Florence Kyndt Charlotte Glinge Pieter G Postema Ahmad S Amin Eline A Nannenberg James S Ware Nicola Whiffin Francesco Mazzarotto Doris Škorić-Milosavljević Christian Krijger Elena Arbelo Dominique Babuty Hector Barajas-Martinez Britt M Beckmann Stéphane Bézieau J Martijn Bos Jeroen Breckpot Oscar Campuzano Silvia Castelletti Candan Celen Sebastian Clauss Anniek Corveleyn Lia Crotti Federica Dagradi Carlo de Asmundis Isabelle Denjoy Sven Dittmann Patrick T Ellinor Cristina Gil Ortuño Carla Giustetto Jean-Baptiste Gourraud Daisuke Hazeki Minoru Horie Taisuke Ishikawa Hideki Itoh Yoshiaki Kaneko Jørgen K Kanters Hiroki Kimoto Maria-Christina Kotta Ingrid P C Krapels Masahiko Kurabayashi Julieta Lazarte Antoine Leenhardt Bart L Loeys Catarina Lundin Takeru Makiyama Jacques Mansourati Raphaël P Martins Andrea Mazzanti Stellan Mörner Carlo Napolitano Kimie Ohkubo Michael Papadakis Boris Rudic Maria Sabater Molina Frédéric Sacher Hatice Sahin Georgia Sarquella-Brugada Regina Sebastiano Sanjay Sharma Mary N Sheppard Keiko Shimamoto M Benjamin Shoemaker Birgit Stallmeyer Johannes Steinfurt Yuji Tanaka David J Tester Keisuke Usuda Paul A van der Zwaag Sonia Van Dooren Lut Van Laer Annika Winbo Bo G Winkel Kenichiro Yamagata Sven Zumhagen Paul G A Volders Steven A Lubitz Charles Antzelevitch Pyotr G Platonov Katja E Odening Dan M Roden Jason D Roberts Jonathan R Skinner Jacob Tfelt-Hansen Maarten P van den Berg Morten S Olesen Pier D Lambiase Martin Borggrefe Kenshi Hayashi Annika Rydberg Tadashi Nakajima Masao Yoshinaga Johan B Saenen Stefan Kääb Pedro Brugada Tomas Robyns Daniela F Giachino Michael J Ackerman Ramon Brugada Josep Brugada Juan R Gimeno Can Hasdemir Pascale Guicheney Silvia G Priori Eric Schulze-Bahr Naomasa Makita Peter J Schwartz Wataru Shimizu Takeshi Aiba Jean-Jacques Schott Richard Redon Seiko Ohno Vincent Probst Elijah R Behr Julien Barc Connie R Bezzina

Genet Med 2020 Sep 7. Epub 2020 Sep 7.

Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.1038/s41436-020-00946-5DOI Listing
September 2020

Animal Models of Atrial Fibrillation.

Circ Res 2020 06 18;127(1):91-110. Epub 2020 Jun 18.

Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston (A.B., K.L., W.J.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.120.316366DOI Listing
June 2020

Modelling Inhomogeneity of Veneer Laminates with a Finite Element Mapping Method Based on Arbitrary Grayscale Images.

Materials (Basel) 2020 Jul 5;13(13). Epub 2020 Jul 5.

Faculty of Mechanical Science and Engineering, Institute of Textile Machinery and High Performance Material Technology (ITM), Technische Universität Dresden, 01062 Dresden, Germany.

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http://dx.doi.org/10.3390/ma13132993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372410PMC
July 2020

Genetic Burden of Birthweight on Atrial Fibrillation: Translational Challenges in Genetic Atrial Fibrillation Studies.

Circ Genom Precis Med 2020 06 16;13(3):e002987. Epub 2020 Jun 16.

Department of Medicine I, University Hospital Munich, Ludwig-Maximilians University Munich (LMU) (P.T., S.C., S.K.).

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http://dx.doi.org/10.1161/CIRCGEN.120.002987DOI Listing
June 2020

Non-coding RNA and Cardiac Electrophysiological Disorders.

Adv Exp Med Biol 2020 ;1229:301-310

Department of Medicine I, University Hospital Munich, Ludwig-Maximilians University Munich (LMU), Munich, Germany.

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http://dx.doi.org/10.1007/978-981-15-1671-9_18DOI Listing
July 2020

Porcine models for studying complications and organ crosstalk in diabetes mellitus.

Cell Tissue Res 2020 May 13;380(2):341-378. Epub 2020 Jan 13.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center, LMU Munich, Feodor-Lynen-Strasse 25, D-81377, Munich, Germany.

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http://dx.doi.org/10.1007/s00441-019-03158-9DOI Listing
May 2020

Molecular Mechanisms of Cardiac Remodeling and Regeneration in Physical Exercise.

Cells 2019 09 23;8(10). Epub 2019 Sep 23.

Department of Medicine I, University Hospital Munich, Campus Grosshadern and Innenstadt, Ludwig-Maximilians University Munich (LMU), 81377 Munich, Germany.

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http://dx.doi.org/10.3390/cells8101128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829258PMC
September 2019

Animal models of arrhythmia: classic electrophysiology to genetically modified large animals.

Nat Rev Cardiol 2019 08;16(8):457-475

Department of Medicine I, University Hospital Munich, Campus Grosshadern, Ludwig-Maximilians University Munich (LMU), Munich, Germany.

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http://www.nature.com/articles/s41569-019-0179-0
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http://dx.doi.org/10.1038/s41569-019-0179-0DOI Listing
August 2019

Genome-Wide Association Studies Revealing the Heritability of Common Atrial Fibrillation: Is Bigger Always Better?

Circ Cardiovasc Genet 2017 12;10(6)

From the Department of Medicine I, Klinikum Grosshadern, University of Munich (LMU), Munich, Germany (S.C., M.F.S., S.K.); and DZHK (German Centre for Cardiovascular Research), Partner site Munich, Munich Health Alliance (MHA), Munich, Germany (S.C., M.F.S., S.K.).

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http://dx.doi.org/10.1161/CIRCGENETICS.117.002005DOI Listing
December 2017

Novel Mutation in (Filamin C) Causes Familial Restrictive Cardiomyopathy.

Circ Cardiovasc Genet 2017 Dec;10(6)

From the Cardiovascular Research Center, Massachusetts General Hospital, Charlestown (N.R.T., M.A.M., D.H., J.Y., V.A.P., R.W.M., S.C., E.D., D.J.M., M.L., S.A.L., I.J.D., P.T.E.); Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA (N.R.T., J.Y., V.A.P., S.A.L., H.L., P.T.E.); Department of Medicine I, Klinikum Grosshadern, University of Munich (LMU), Germany (S.C.); German Centre for Cardiovascular Research, Partner site Munich, Germany (S.C.); Division of Cardiology (M.A.S., D.J.M., N.S.S., M.L., S.A.L., I.J.D., P.T.E.) and Department of Pathology, Center for Systems Biology (J.R.S.), Massachusetts General Hospital, Boston; and Computational Biomedicine Section, Department of Medicine, Boston University School of Medicine, MA (H.L.).

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https://www.ahajournals.org/doi/10.1161/CIRCGENETICS.117.001
Publisher Site
http://dx.doi.org/10.1161/CIRCGENETICS.117.001780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802346PMC
December 2017

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Authors:
Ingrid E Christophersen Michiel Rienstra Carolina Roselli Xiaoyan Yin Bastiaan Geelhoed John Barnard Honghuang Lin Dan E Arking Albert V Smith Christine M Albert Mark Chaffin Nathan R Tucker Molong Li Derek Klarin Nathan A Bihlmeyer Siew-Kee Low Peter E Weeke Martina Müller-Nurasyid J Gustav Smith Jennifer A Brody Maartje N Niemeijer Marcus Dörr Stella Trompet Jennifer Huffman Stefan Gustafsson Claudia Schurmann Marcus E Kleber Leo-Pekka Lyytikäinen Ilkka Seppälä Rainer Malik Andrea R V R Horimoto Marco Perez Juha Sinisalo Stefanie Aeschbacher Sébastien Thériault Jie Yao Farid Radmanesh Stefan Weiss Alexander Teumer Seung Hoan Choi Lu-Chen Weng Sebastian Clauss Rajat Deo Daniel J Rader Svati H Shah Albert Sun Jemma C Hopewell Stephanie Debette Ganesh Chauhan Qiong Yang Bradford B Worrall Guillaume Paré Yoichiro Kamatani Yanick P Hagemeijer Niek Verweij Joylene E Siland Michiaki Kubo Jonathan D Smith David R Van Wagoner Joshua C Bis Siegfried Perz Bruce M Psaty Paul M Ridker Jared W Magnani Tamara B Harris Lenore J Launer M Benjamin Shoemaker Sandosh Padmanabhan Jeffrey Haessler Traci M Bartz Melanie Waldenberger Peter Lichtner Marina Arendt Jose E Krieger Mika Kähönen Lorenz Risch Alfredo J Mansur Annette Peters Blair H Smith Lars Lind Stuart A Scott Yingchang Lu Erwin B Bottinger Jussi Hernesniemi Cecilia M Lindgren Jorge A Wong Jie Huang Markku Eskola Andrew P Morris Ian Ford Alex P Reiner Graciela Delgado Lin Y Chen Yii-Der Ida Chen Roopinder K Sandhu Man Li Eric Boerwinkle Lewin Eisele Lars Lannfelt Natalia Rost Christopher D Anderson Kent D Taylor Archie Campbell Patrik K Magnusson David Porteous Lynne J Hocking Efthymia Vlachopoulou Nancy L Pedersen Kjell Nikus Marju Orho-Melander Anders Hamsten Jan Heeringa Joshua C Denny Jennifer Kriebel Dawood Darbar Christopher Newton-Cheh Christian Shaffer Peter W Macfarlane Stefanie Heilmann-Heimbach Peter Almgren Paul L Huang Nona Sotoodehnia Elsayed Z Soliman Andre G Uitterlinden Albert Hofman Oscar H Franco Uwe Völker Karl-Heinz Jöckel Moritz F Sinner Henry J Lin Xiuqing Guo Martin Dichgans Erik Ingelsson Charles Kooperberg Olle Melander Ruth J F Loos Jari Laurikka David Conen Jonathan Rosand Pim van der Harst Marja-Liisa Lokki Sekar Kathiresan Alexandre Pereira J Wouter Jukema Caroline Hayward Jerome I Rotter Winfried März Terho Lehtimäki Bruno H Stricker Mina K Chung Stephan B Felix Vilmundur Gudnason Alvaro Alonso Dan M Roden Stefan Kääb Daniel I Chasman Susan R Heckbert Emelia J Benjamin Toshihiro Tanaka Kathryn L Lunetta Steven A Lubitz Patrick T Ellinor

Nat Genet 2017 07;49(8):1286

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http://dx.doi.org/10.1038/ng0817-1286cDOI Listing
July 2017

Influence of polyphenol-rich diet on exercise-induced immunomodulation in male endurance athletes.

Appl Physiol Nutr Metab 2017 Oct 7;42(10):1023-1030. Epub 2017 Jun 7.

a Department of Cardiology, University Hospital Grosshadern, Ludwig-Maximilians University, DE-81377 Munich, Germany.

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http://dx.doi.org/10.1139/apnm-2017-0063DOI Listing
October 2017

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Authors:
Ingrid E Christophersen Michiel Rienstra Carolina Roselli Xiaoyan Yin Bastiaan Geelhoed John Barnard Honghuang Lin Dan E Arking Albert V Smith Christine M Albert Mark Chaffin Nathan R Tucker Molong Li Derek Klarin Nathan A Bihlmeyer Siew-Kee Low Peter E Weeke Martina Müller-Nurasyid J Gustav Smith Jennifer A Brody Maartje N Niemeijer Marcus Dörr Stella Trompet Jennifer Huffman Stefan Gustafsson Claudia Schurmann Marcus E Kleber Leo-Pekka Lyytikäinen Ilkka Seppälä Rainer Malik Andrea R V R Horimoto Marco Perez Juha Sinisalo Stefanie Aeschbacher Sébastien Thériault Jie Yao Farid Radmanesh Stefan Weiss Alexander Teumer Seung Hoan Choi Lu-Chen Weng Sebastian Clauss Rajat Deo Daniel J Rader Svati H Shah Albert Sun Jemma C Hopewell Stephanie Debette Ganesh Chauhan Qiong Yang Bradford B Worrall Guillaume Paré Yoichiro Kamatani Yanick P Hagemeijer Niek Verweij Joylene E Siland Michiaki Kubo Jonathan D Smith David R Van Wagoner Joshua C Bis Siegfried Perz Bruce M Psaty Paul M Ridker Jared W Magnani Tamara B Harris Lenore J Launer M Benjamin Shoemaker Sandosh Padmanabhan Jeffrey Haessler Traci M Bartz Melanie Waldenberger Peter Lichtner Marina Arendt Jose E Krieger Mika Kähönen Lorenz Risch Alfredo J Mansur Annette Peters Blair H Smith Lars Lind Stuart A Scott Yingchang Lu Erwin B Bottinger Jussi Hernesniemi Cecilia M Lindgren Jorge A Wong Jie Huang Markku Eskola Andrew P Morris Ian Ford Alex P Reiner Graciela Delgado Lin Y Chen Yii-Der Ida Chen Roopinder K Sandhu Man Li Eric Boerwinkle Lewin Eisele Lars Lannfelt Natalia Rost Christopher D Anderson Kent D Taylor Archie Campbell Patrik K Magnusson David Porteous Lynne J Hocking Efthymia Vlachopoulou Nancy L Pedersen Kjell Nikus Marju Orho-Melander Anders Hamsten Jan Heeringa Joshua C Denny Jennifer Kriebel Dawood Darbar Christopher Newton-Cheh Christian Shaffer Peter W Macfarlane Stefanie Heilmann-Heimbach Peter Almgren Paul L Huang Nona Sotoodehnia Elsayed Z Soliman Andre G Uitterlinden Albert Hofman Oscar H Franco Uwe Völker Karl-Heinz Jöckel Moritz F Sinner Henry J Lin Xiuqing Guo Martin Dichgans Erik Ingelsson Charles Kooperberg Olle Melander Ruth J F Loos Jari Laurikka David Conen Jonathan Rosand Pim van der Harst Marja-Liisa Lokki Sekar Kathiresan Alexandre Pereira J Wouter Jukema Caroline Hayward Jerome I Rotter Winfried März Terho Lehtimäki Bruno H Stricker Mina K Chung Stephan B Felix Vilmundur Gudnason Alvaro Alonso Dan M Roden Stefan Kääb Daniel I Chasman Susan R Heckbert Emelia J Benjamin Toshihiro Tanaka Kathryn L Lunetta Steven A Lubitz Patrick T Ellinor

Nat Genet 2017 Jun 17;49(6):946-952. Epub 2017 Apr 17.

Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585859PMC
June 2017

Impact of polyphenols on physiological stress and cardiac burden in marathon runners - results from a substudy of the BeMaGIC study.

Appl Physiol Nutr Metab 2017 May 16;42(5):523-528. Epub 2017 Jan 16.

a Medizinische Klinik und Poliklinik I, University Hospital of Munich, Campus Grosshadern, Ludwig-Maximilians-Universität München (LMU), DE-81377 Munich, Germany.

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http://dx.doi.org/10.1139/apnm-2016-0457DOI Listing
May 2017

A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a.

Am J Hum Genet 2016 Dec 17;99(6):1281-1291. Epub 2016 Nov 17.

Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA 02129, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142106PMC
December 2016

MicroRNAs as a diagnostic tool for heart failure and atrial fibrillation.

Curr Opin Pharmacol 2016 Apr 4;27:24-30. Epub 2016 Feb 4.

Department of Medicine I, University Hospital Munich, Campus Grosshadern, Ludwig-Maximilians-University Munich, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2016.01.001DOI Listing
April 2016

The Role of MicroRNAs in Antiarrhythmic Therapy for Atrial Fibrillation.

Arrhythm Electrophysiol Rev 2015 Dec 1;4(3):146-55. Epub 2015 Dec 1.

University Hospital Munich, Ludwig-Maximilians University Munich; DZHK (German Centre for Cardiovascular Research), Partner Site Munich, Germany.

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http://dx.doi.org/10.15420/aer.2015.4.3.146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732177PMC
December 2015

Common variation in atrial fibrillation: navigating the path from genetic association to mechanism.

Cardiovasc Res 2016 Apr 4;109(4):493-501. Epub 2016 Jan 4.

Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA 02129, USA Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, MA, USA

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http://dx.doi.org/10.1093/cvr/cvv283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777911PMC
April 2016

Does Atrial Fibrillation Follow Function? Ion Channel Mutations and Lone Atrial Fibrillation.

Circ Arrhythm Electrophysiol 2015 Oct;8(5):1005-6

From the Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA (S.C., P.T.E.); Department of Medicine I, Klinikum Grosshadern, University of Munich (LMU), Munich, Germany (S.C.); DZHK (German Centre for Cardiovascular Research), Partner site Munich, Germany (S.C.); and Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA (P.T.E.).

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http://dx.doi.org/10.1161/CIRCEP.115.003330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751579PMC
October 2015

Detailed characterization of microRNA changes in a canine heart failure model: Relationship to arrhythmogenic structural remodeling.

J Mol Cell Cardiol 2014 Dec 12;77:113-24. Epub 2014 Oct 12.

Department of Medicine and Research Center, Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada; Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2014.10.001DOI Listing
December 2014

Impact of real-time contact force and impedance measurement in pulmonary vein isolation procedures for treatment of atrial fibrillation.

Clin Res Cardiol 2014 Feb 6;103(2):97-106. Epub 2013 Oct 6.

Department of Medicine I, Klinikum Grosshadern, University of Munich and Munich Heart Alliance, Marchionistraße 15, 81377, Munich, Germany,

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http://dx.doi.org/10.1007/s00392-013-0625-7DOI Listing
February 2014

MicroRNA29: a mechanistic contributor and potential biomarker in atrial fibrillation.

Circulation 2013 Apr 4;127(14):1466-75, 1475e1-28. Epub 2013 Mar 4.

Montreal Heart Institute Research Center, 5000 Belanger St E, Montreal, Quebec, H1T 1C8, Canada.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.001207DOI Listing
April 2013

Meta-analysis identifies six new susceptibility loci for atrial fibrillation.

Nat Genet 2012 Apr 29;44(6):670-5. Epub 2012 Apr 29.

Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.2261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366038PMC
April 2012

Is Pitx2 growing up?

Circ Cardiovasc Genet 2011 Apr;4(2):105-7

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http://dx.doi.org/10.1161/CIRCGENETICS.111.959791DOI Listing
April 2011

Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif.

Am J Physiol Renal Physiol 2009 Apr 21;296(4):F867-74. Epub 2009 Jan 21.

Medizinische Poliklinik, Klinikum der Universität-Innenstadt, Pettenkoferstr. 8a, 80336 Munich, Germany.

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http://dx.doi.org/10.1152/ajprenal.90213.2008DOI Listing
April 2009