Publications by authors named "Sebastian Bultmann"

34Publications

Author Correction: Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals.

Authors:
Christopher B Mulholland Atsuya Nishiyama Joel Ryan Ryohei Nakamura Merve Yiğit Ivo M Glück Carina Trummer Weihua Qin Michael D Bartoschek Franziska R Traube Edris Parsa Enes Ugur Miha Modic Aishwarya Acharya Paul Stolz Christoph Ziegenhain Michael Wierer Wolfgang Enard Thomas Carell Don C Lamb Hiroyuki Takeda Makoto Nakanishi Sebastian Bultmann Heinrich Leonhardt

Nat Commun 2020 Dec 17;11(1):6443. Epub 2020 Dec 17.

Department of Biology II and Center for Integrated Protein Science Munich (CIPSM), Human Biology and BioImaging, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany.

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December 2020

Staying true to yourself: mechanisms of DNA methylation maintenance in mammals.

Authors:
Nataliya Petryk Sebastian Bultmann Till Bartke Pierre-Antoine Defossez

Nucleic Acids Res 2020 Dec 9. Epub 2020 Dec 9.

Epigenetics and Cell Fate Centre, UMR7216 CNRS, Université de Paris, F-75013 Paris, France.

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December 2020

Live cell PNA labelling enables erasable fluorescence imaging of membrane proteins.

Authors:
Georgina C Gavins Katharina Gröger Michael D Bartoschek Philipp Wolf Annette G Beck-Sickinger Sebastian Bultmann Oliver Seitz

Nat Chem 2021 Jan 7;13(1):15-23. Epub 2020 Dec 7.

Department of Chemistry, Humboldt-Universität zu Berlin, Berlin, Germany.

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January 2021

Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals.

Authors:
Christopher B Mulholland Atsuya Nishiyama Joel Ryan Ryohei Nakamura Merve Yiğit Ivo M Glück Carina Trummer Weihua Qin Michael D Bartoschek Franziska R Traube Edris Parsa Enes Ugur Miha Modic Aishwarya Acharya Paul Stolz Christoph Ziegenhain Michael Wierer Wolfgang Enard Thomas Carell Don C Lamb Hiroyuki Takeda Makoto Nakanishi Sebastian Bultmann Heinrich Leonhardt

Nat Commun 2020 11 24;11(1):5972. Epub 2020 Nov 24.

Department of Biology II and Center for Integrated Protein Science Munich (CIPSM), Human Biology and BioImaging, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany.

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November 2020

METTL6 is a tRNA mC methyltransferase that regulates pluripotency and tumor cell growth.

Authors:
Valentina V Ignatova Steffen Kaiser Jessica Sook Yuin Ho Xinyang Bing Paul Stolz Ying Xim Tan Chee Leng Lee Florence Pik Hoon Gay Palma Rico Lastres Raffaele Gerlini Birgit Rathkolb Antonio Aguilar-Pimentel Adrián Sanz-Moreno Tanja Klein-Rodewald Julia Calzada-Wack Emil Ibragimov Magdalena Valenta Saulius Lukauskas Andrea Pavesi Susan Marschall Stefanie Leuchtenberger Helmut Fuchs Valerie Gailus-Durner Martin Hrabe de Angelis Sebastian Bultmann Oliver J Rando Ernesto Guccione Stefanie M Kellner Robert Schneider

Sci Adv 2020 Aug 26;6(35):eaaz4551. Epub 2020 Aug 26.

Institute of Functional Epigenetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany.

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August 2020

Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency.

Authors:
Christopher B Mulholland Franziska R Traube Enes Ugur Edris Parsa Eva-Maria Eckl Maximilian Schönung Miha Modic Michael D Bartoschek Paul Stolz Joel Ryan Thomas Carell Heinrich Leonhardt Sebastian Bultmann

Sci Rep 2020 07 21;10(1):12066. Epub 2020 Jul 21.

Department of Biology II and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany.

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July 2020

Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma.

Authors:
Deepak Bararia Johannes A Hildebrand Sebastian Stolz Sarah Haebe Stefan Alig Christopher P Trevisani Francisco Osorio-Barrios Michael D Bartoschek Michael Mentz Alessandro Pastore Erik Gaitzsch Michael Heide Vindi Jurinovic Katharina Rautter Jay Gunawardana Muhammed B Sabdia Monika Szczepanowski Julia Richter Wolfram Klapper Abner Louissaint Christina Ludwig Sebastian Bultmann Heinrich Leonhardt Sebastian Eustermann Karl-Peter Hopfner Wolfgang Hiddemann Michael von Bergwelt-Baildon Christian Steidl Robert Kridel Joshua W D Tobin Maher K Gandhi David M Weinstock Marc Schmidt-Supprian Menyhárt B Sárosi Martina Rudelius Verena Passerini Josef Mautner Oliver Weigert

Cell Rep 2020 05 23;31(5):107522. Epub 2020 Apr 23.

Department of Medicine III, Laboratory for Experimental Leukemia and Lymphoma Research (ELLF), Hospital of the Ludwig-Maximilians-University (LMU), Munich, Bavaria 81377, Germany; German Cancer Consortium (DKTK), Munich, Bavaria 81377, Germany; German Cancer Research Center (DKFZ), Heidelberg, Baden-Wuerttemberg 69120, Germany. Electronic address:

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May 2020

The rRNA mA methyltransferase METTL5 is involved in pluripotency and developmental programs.

Authors:
Valentina V Ignatova Paul Stolz Steffen Kaiser Tobias H Gustafsson Palma Rico Lastres Adrián Sanz-Moreno Yi-Li Cho Oana V Amarie Antonio Aguilar-Pimentel Tanja Klein-Rodewald Julia Calzada-Wack Lore Becker Susan Marschall Markus Kraiger Lillian Garrett Claudia Seisenberger Sabine M Hölter Kayla Borland Erik Van De Logt Pascal W T C Jansen Marijke P Baltissen Magdalena Valenta Michiel Vermeulen Wolfgang Wurst Valerie Gailus-Durner Helmut Fuchs Martin Hrabe de Angelis Oliver J Rando Stefanie M Kellner Sebastian Bultmann Robert Schneider

Genes Dev 2020 05 26;34(9-10):715-729. Epub 2020 Mar 26.

Institute of Functional Epigenetics, Helmholtz Zentrum München (HMGU), Neuherberg 85764, Germany.

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May 2020

Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.

Authors:
Atsuya Nishiyama Christopher B Mulholland Sebastian Bultmann Satomi Kori Akinori Endo Yasushi Saeki Weihua Qin Carina Trummer Yoshie Chiba Haruka Yokoyama Soichiro Kumamoto Toru Kawakami Hironobu Hojo Genta Nagae Hiroyuki Aburatani Keiji Tanaka Kyohei Arita Heinrich Leonhardt Makoto Nakanishi

Nat Commun 2020 03 6;11(1):1222. Epub 2020 Mar 6.

Division of Cancer Cell Biology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan.

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March 2020

Loss of KDM6A confers drug resistance in acute myeloid leukemia.

Authors:
Sophie M Stief Anna-Li Hanneforth Sabrina Weser Raphael Mattes Michela Carlet Wen-Hsin Liu Michael D Bartoschek Helena Domínguez Moreno Matthias Oettle Julia Kempf Binje Vick Bianka Ksienzyk Belay Tizazu Maja Rothenberg-Thurley Hilmar Quentmeier Wolfgang Hiddemann Sebastian Vosberg Philipp A Greif Klaus H Metzeler Gunnar Schotta Sebastian Bultmann Irmela Jeremias Heinrich Leonhardt Karsten Spiekermann

Leukemia 2020 01 14;34(1):50-62. Epub 2019 Jun 14.

Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.

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January 2020

Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.

Authors:
Julia K Götzl Matthias Brendel Georg Werner Samira Parhizkar Laura Sebastian Monasor Gernot Kleinberger Alessio-Vittorio Colombo Maximilian Deussing Matias Wagner Juliane Winkelmann Janine Diehl-Schmid Johannes Levin Katrin Fellerer Anika Reifschneider Sebastian Bultmann Peter Bartenstein Axel Rominger Sabina Tahirovic Scott T Smith Charlotte Madore Oleg Butovsky Anja Capell Christian Haass

EMBO Mol Med 2019 06;11(6)

Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany

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June 2019

Critical Role of the UBL Domain in Stimulating the E3 Ubiquitin Ligase Activity of UHRF1 toward Chromatin.

Authors:
Benjamin M Foster Paul Stolz Christopher B Mulholland Alex Montoya Holger Kramer Sebastian Bultmann Till Bartke

Mol Cell 2018 11 1;72(4):739-752.e9. Epub 2018 Nov 1.

Institute of Functional Epigenetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK. Electronic address:

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November 2018

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.

Authors:
Gilles Gasparoni Sebastian Bultmann Pavlo Lutsik Theo F J Kraus Sabrina Sordon Julia Vlcek Vanessa Dietinger Martina Steinmaurer Melanie Haider Christopher B Mulholland Thomas Arzberger Sigrun Roeber Matthias Riemenschneider Hans A Kretzschmar Armin Giese Heinrich Leonhardt Jörn Walter

Epigenetics Chromatin 2018 07 25;11(1):41. Epub 2018 Jul 25.

Department of Genetics, University of Saarland (UdS), Campus, 66123, Saarbrücken, Germany.

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July 2018

Applications of the CRISPR/Cas system beyond gene editing.

Authors:
Tobias Anton Elisabeth Karg Sebastian Bultmann

Biol Methods Protoc 2018 10;3(1):bpy002. Epub 2018 May 10.

Department of Biology II and Center for Integrated Protein Science Munich (CIPSM), LMU Munich, 82152 Martinsried, Germany.

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May 2018

Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.

Authors:
Arne Hinrichs Barbara Kessler Mayuko Kurome Andreas Blutke Elisabeth Kemter Maren Bernau Armin M Scholz Birgit Rathkolb Simone Renner Sebastian Bultmann Heinrich Leonhardt Martin Hrabĕ de Angelis Hiroshi Nagashima Andreas Hoeflich Werner F Blum Martin Bidlingmaier Rüdiger Wanke Maik Dahlhoff Eckhard Wolf

Mol Metab 2018 05 15;11:113-128. Epub 2018 Mar 15.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Feodor-Lynen-Str. 25, 81377 Munich, Germany; Center for Innovative Medical Models (CiMM), Department of Veterinary Sciences, LMU Munich, Hackerstr. 27, 85764 Oberschleißheim, Germany; Meiji University International Institute for Bio-Resource Research, 1-1-1 Higashimita, Tama, Kawasaki, 214-8571, Japan; German Center for Diabetes Research (DZD), Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany; Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, 81377 Munich, Germany. Electronic address:

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May 2018

Entering the post-epigenomic age: back to epigenetics.

Authors:
Sebastian Bultmann Stefan H Stricker

Open Biol 2018 03;8(3)

MCN Junior Research Group, Munich Center for Neurosciences, Ludwig-Maximilian-Universität, Biocenter, Grosshaderner Strasse 9, Planegg-Martinsried 82152, Germany

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March 2018

Azacitidine combined with the selective FLT3 kinase inhibitor crenolanib disrupts stromal protection and inhibits expansion of residual leukemia-initiating cells in -ITD AML with concurrent epigenetic mutations.

Authors:
Anne-Kathrin Garz Saskia Wolf Sonja Grath Verena Gaidzik Stefan Habringer Binje Vick Martina Rudelius Christoph Ziegenhain Sylvia Herold Marie-Theresa Weickert Martha Smets Christian Peschel Robert A J Oostendorp Sebastian Bultmann Irmela Jeremias Christian Thiede Konstanze Döhner Ulrich Keller Katharina S Götze

Oncotarget 2017 Dec 16;8(65):108738-108759. Epub 2017 Oct 16.

Department of Medicine III, Klinikum rechts der Isar, Technische Universität München (TUM), Munich, Germany.

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December 2017

Ubiquitome Analysis Reveals PCNA-Associated Factor 15 (PAF15) as a Specific Ubiquitination Target of UHRF1 in Embryonic Stem Cells.

Authors:
Elisabeth Karg Martha Smets Joel Ryan Ignasi Forné Weihua Qin Christopher B Mulholland Georgia Kalideris Axel Imhof Sebastian Bultmann Heinrich Leonhardt

J Mol Biol 2017 12 18;429(24):3814-3824. Epub 2017 Oct 18.

Department of Biology II and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians-Universität München, Großhaderner Str. 2, 82152 Planegg-Martinsried, Germany. Electronic address:

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December 2017

CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes.

Authors:
Maik Dahlhoff Nadège Gaborit Sebastian Bultmann Heinrich Leonhardt Yosef Yarden Marlon R Schneider

FEBS J 2017 10 14;284(19):3339-3349. Epub 2017 Sep 14.

German Centre for the Protection of Laboratory Animals (Bf3R), German Federal Institute for Risk Assessment (BfR), Berlin, Germany.

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October 2017

TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.

Authors:
Fargol Mazaheri Nicolas Snaidero Gernot Kleinberger Charlotte Madore Anna Daria Georg Werner Susanne Krasemann Anja Capell Dietrich Trümbach Wolfgang Wurst Bettina Brunner Sebastian Bultmann Sabina Tahirovic Martin Kerschensteiner Thomas Misgeld Oleg Butovsky Christian Haass

EMBO Rep 2017 07 8;18(7):1186-1198. Epub 2017 May 8.

German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany

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July 2017