Sebastian Brandner

Sebastian Brandner

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Sebastian Brandner

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Data Sets for the Reporting of Tumors of the Central Nervous System.

Arch Pathol Lab Med 2019 Jun 20. Epub 2019 Jun 20.

From the Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (Dr Louis); the Department of Pathology, Amsterdam Universities Medical Center/VUmc CCA Brain Tumor Center, Amsterdam, the Netherlands (Dr Wesseling); the Department of Pathology, Princess Máxima Center for Pediatric Oncology, and University Medical Center Utrecht, Utrecht, the Netherlands (Dr Wesseling); Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, United Kingdom (Dr Brandner); the Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom (Dr Brandner); the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (Dr Brat); the Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee (Dr Ellison); the Department of Radiology, Oncology and Anatomic Pathology, University La Sapienza, Rome, Italy (Dr Giangaspero); IRCCS Neuromed, Pozzilli, Isernia, Italy (Dr Giangaspero); the Department of Pathology, University of Louisville School of Medicine, Louisville, Kentucky (Dr Hattab); the Department of Laboratory Medicine & Pathobiology, The Hospital for Sick Children, Toronto, Ontario, Canada (Dr Hawkins); Project Management Office, Royal College of Pathologists of Australasia, Sydney, Australia (Ms Judge); the Departments of Pathology, Neurology, and Neurosurgery, University of Colorado, Aurora (Dr Kleinschmidt-DeMasters); the Department of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, Tokyo, Japan (Dr Komori); the Department of Pathology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan (Dr Komori); Alfred Anatomical Pathology and NNF, Victorian Brain Bank, Carlton, Victoria, Australia (Dr McLean); Institute of Neuropathology, University Hospital Münster, Münster, Germany (Dr Paulus); Division of Neuropathology, Department of Pathology, University of California, San Francisco (Dr Perry); the Department of Neuropathology, Heinrich Heine University, Düsseldorf, Germany (Dr Reifenberger); German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Düsseldorf, Germany (Dr Reifenberger); the Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland (Dr Weller); and the Department of Histopathology, Addenbrookes Hospital, Cambridge, United Kingdom (Dr Rous); ICCR Steering Group Representative (Dr Rous).

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http://dx.doi.org/10.5858/arpa.2018-0565-OADOI Listing
June 2019

Modelling MR and clinical features in grade II/III astrocytomas to predict IDH mutation status.

Eur J Radiol 2019 May 14;114:120-127. Epub 2019 Mar 14.

Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, UK; National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X193009
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http://dx.doi.org/10.1016/j.ejrad.2019.03.003DOI Listing
May 2019

Filtration-histogram based magnetic resonance texture analysis (MRTA) for glioma IDH and 1p19q genotyping.

Eur J Radiol 2019 Apr 13;113:116-123. Epub 2019 Feb 13.

Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK; Department of Brain Rehabilitation and Repair, UCL Institute of Neurology, Queen Square, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2019.02.014DOI Listing
April 2019

Autosomal dominant optic atrophy and cataract "plus" phenotype including axonal neuropathy.

Neurol Genet 2019 Apr 1;5(2):e322. Epub 2019 Apr 1.

Department of Neuromuscular Diseases (A.H., A.C., M.G.H., M.M.R.), UCL Queen Square Institute of Neurology and the National Hospital for Neurology and Neurosurgery, University College London Hospitals; Department of Molecular Neuroscience (A.M.P., H.H.), UCL Queen Square Institute of Neurology; Department of Neuro-ophthalmology (F.B.F.R.C.O.), the National Hospital for Neurology and Neurosurgery, University College London Hospitals; Division of Neuropathology (Z.J., S.B.), the National Hospital for Neurology and Neurosurgery, University College London Hospitals; Department of Clinical and Movement Neurosciences (Z.J.), UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (L.D., S.S.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Department of Human Genetics and Hussman Institute for Human Genomics (A.P.R., S.Z.), University of Miami, FL; Department of Neurogenetics (C.E.W., J.M.P.), the National Hospital for Neurology and Neurosurgery, University College London Hospitals; Neurometabolic Unit (I.P.H.), the National Hospital for Neurology and Neurosurgery, University College London Hospitals; and Department of Neurodegenerative Disease (S.B.), UCL Queen Square Institute of Neurology, London, United Kingdom.

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http://dx.doi.org/10.1212/NXG.0000000000000322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501639PMC
April 2019

Early neurophysiological biomarkers and spinal cord pathology in inherited prion disease.

Brain 2019 Mar;142(3):760-770

National Prion Clinic, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust (UCLH), London, UK.

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https://academic.oup.com/brain/advance-article/doi/10.1093/b
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http://dx.doi.org/10.1093/brain/awy358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391599PMC
March 2019

Early onset cerebral amyloid angiopathy following childhood exposure to cadaveric dura.

Ann Neurol 2019 Feb 17;85(2):284-290. Epub 2019 Jan 17.

Stroke Research Centre, Department of Brain Repair and Rehabilitation, University College London Queen Square Institute of Neurology and National Hospital for Neurology and Neurosurgery, London.

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http://doi.wiley.com/10.1002/ana.25407
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http://dx.doi.org/10.1002/ana.25407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492172PMC
February 2019

Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre.

Acta Neuropathol Commun 2019 Feb 20;7(1):24. Epub 2019 Feb 20.

Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, WC1N 3BG, UK.

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https://actaneurocomms.biomedcentral.com/articles/10.1186/s4
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http://dx.doi.org/10.1186/s40478-019-0668-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381711PMC
February 2019

Evaluating the causality of novel sequence variants in the prion protein gene by example.

Neurobiol Aging 2018 11 15;71:265.e1-265.e7. Epub 2018 May 15.

MRC Prion Unit, UCL Institute of Prion Diseases, London, UK; National Prion Clinic, National Hospital for Neurology and Neurosurgery, UCLH NHS Foundation Trust, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175539PMC
November 2018

Methods for Molecular Diagnosis of Human Prion Disease.

Methods Mol Biol 2017 ;1658:311-346

MRC Prion Unit at UCL, UCL Institute of Prion Diseases, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1007/978-1-4939-7244-9_22DOI Listing
May 2018

Evidence of amyloid-β cerebral amyloid angiopathy transmission through neurosurgery.

Acta Neuropathol 2018 05 15;135(5):671-679. Epub 2018 Feb 15.

Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1007/s00401-018-1822-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904220PMC
May 2018

A diagnostic conundrum.

Pract Neurol 2018 04 23;18(2):137-142. Epub 2018 Jan 23.

Department of Molecular Neuroscience, MRC Centre for Neuromuscular Diseases, National Hospital of Neurology and Neurosurgery, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1136/practneurol-2017-001801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513759PMC
April 2018

Visualization of CSF Flow with Time-resolved 3D MR Velocity Mapping in Aqueductal Stenosis Before and After Endoscopic Third Ventriculostomy : A Feasibility Study.

Clin Neuroradiol 2018 Mar 8;28(1):69-74. Epub 2016 Aug 8.

Department of Neurosurgery, Friedrich-Alexander University Erlangen-Nuremberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00062-016-0530-3DOI Listing
March 2018

Neurological update: gliomas and other primary brain tumours in adults.

J Neurol 2018 Mar 2;265(3):717-727. Epub 2017 Nov 2.

Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, Queen Square, London, WC1N 3BG, UK.

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http://link.springer.com/10.1007/s00415-017-8652-3
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http://dx.doi.org/10.1007/s00415-017-8652-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834564PMC
March 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

Neurological outcome and frequency of overdrainage in normal pressure hydrocephalus directly correlates with implanted ventriculo-peritoneal shunt valve type.

Neurol Res 2017 Jul 1;39(7):601-605. Epub 2017 May 1.

a Department of Neurosurgery , Friedrich-Alexander University Erlangen-Nuremberg (FAU) , Erlangen , Germany.

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http://dx.doi.org/10.1080/01616412.2017.1321300DOI Listing
July 2017

Leprosy in a patient infected with HIV.

Pract Neurol 2017 Apr 9;17(2):135-139. Epub 2016 Dec 9.

St George's University Hospitals, London, UK.

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http://dx.doi.org/10.1136/practneurol-2016-001519DOI Listing
April 2017

Prion disease: experimental models and reality.

Acta Neuropathol 2017 02 13;133(2):197-222. Epub 2017 Jan 13.

Department of Neurodegenerative Disease, UCL Institute of Neurology and Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1007/s00401-017-1670-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250673PMC
February 2017

World Health Organization grade III meningiomas. A retrospective study for outcome and prognostic factors assessment.

Br J Neurosurg 2015 22;29(5):693-8. Epub 2015 Jun 22.

d Department of Neurosurgery , National Hospital for Neurology and Neurosurgery , London , UK.

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http://dx.doi.org/10.3109/02688697.2015.1054350DOI Listing
September 2016

Collinge et al. reply.

Nature 2016 09;537(7620):E7-9

Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1038/nature19087DOI Listing
September 2016

Spatiotemporal Pattern of Human Cortical and Subcortical Activity during Early-Stage Odor Processing.

Chem Senses 2016 Aug 31. Epub 2016 Aug 31.

Institute of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen-Nürnberg, Krankenhausstr. 9, D-91054 Erlangen, Germany

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http://dx.doi.org/10.1093/chemse/bjw074DOI Listing
August 2016

Genetic and phenotypic characterization of complex hereditary spastic paraplegia.

Brain 2016 07 23;139(Pt 7):1904-18. Epub 2016 May 23.

1 Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK 2 Alzheimer's Disease Research Centre, Department of Neurology, Harvard Medical School and Massachusetts General Hospital, 114 16th Street, Charlestown, MA 02129, USA

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http://dx.doi.org/10.1093/brain/aww111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939695PMC
July 2016

Inflammatory demyelination without astrocyte loss in MOG antibody-positive NMOSD.

Neurology 2016 07 15;87(2):229-31. Epub 2016 Jun 15.

From the National Hospital for Neurology & Neurosurgery, UCLH NHS Foundation Trust and UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000002844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940064PMC
July 2016

Collinge et al. reply.

Nature 2016 07;535(7611):E2-3

Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1038/nature18603DOI Listing
July 2016

Early CSF and Serum S100B Concentrations for Outcome Prediction in Traumatic Brain Injury and Subarachnoid Hemorrhage.

Clin Neurol Neurosurg 2016 Jun 8;145:79-83. Epub 2016 Apr 8.

Department of Neurosurgery, Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clineuro.2016.04.005DOI Listing
June 2016

Imatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling.

Sci Rep 2016 06 13;6:27378. Epub 2016 Jun 13.

Centre for Cardiovascular Biology and Medicine, Division of Medicine, The Rayne Building, London WC1E 6JJ, United Kingdom.

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http://dx.doi.org/10.1038/srep27378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904410PMC
June 2016

Hereditary leukoencephalopathy with axonal spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an adult onset leukodystrophy series.

J Neurol Neurosurg Psychiatry 2016 May 2;87(5):512-9. Epub 2015 May 2.

Department of Molecular Neuroscience, The National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, Queen Square, London, UK Neurogenetics Laboratory, The National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1136/jnnp-2015-310788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853550PMC
May 2016

Clinical Trial Simulations Based on Genetic Stratification and the Natural History of a Functional Outcome Measure in Creutzfeldt-Jakob Disease.

JAMA Neurol 2016 Apr;73(4):447-55

Medical Research Council Prion Unit, Department of Neurodegnerative Disease, University College London Institute of Neurology, London, England2National Prion Clinic, National Hospital for Neurology and Neurosurgery, University College London Hospitals, NH.

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http://dx.doi.org/10.1001/jamaneurol.2015.4885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701731PMC
April 2016

Prion-mediated neurodegeneration is associated with early impairment of the ubiquitin-proteasome system.

Acta Neuropathol 2016 Mar 8;131(3):411-25. Epub 2015 Dec 8.

Department of Neurodegenerative Disease, University College London, Institute of Neurology, Queen Square, London, WC1N 3BG, UK.

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http://link.springer.com/10.1007/s00401-015-1508-y
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http://dx.doi.org/10.1007/s00401-015-1508-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752964PMC
March 2016

Generation of brain tumours in mice by Cre-mediated recombination of neural progenitors in situ with the tamoxifen metabolite endoxifen.

Dis Model Mech 2016 Feb 24;9(2):211-20. Epub 2015 Dec 24.

Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK

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http://dx.doi.org/10.1242/dmm.022715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770146PMC
February 2016

Imaging features of spinal tanycytic ependymoma.

Neuroradiol J 2016 Feb 11;29(1):61-5. Epub 2016 Jan 11.

Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, UK.

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http://neu.sagepub.com/content/29/1/61.full.pdf
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http://neu.sagepub.com/lookup/doi/10.1177/1971400915621322
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http://dx.doi.org/10.1177/1971400915621322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978340PMC
February 2016

Pharmacological removal of serum amyloid P component from intracerebral plaques and cerebrovascular Aβ amyloid deposits in vivo.

Open Biol 2016 Feb;6(2):150202

Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, Royal Free Campus, University College London, Rowland Hill Street, London NW3 2PF, UK

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http://dx.doi.org/10.1098/rsob.150202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772805PMC
February 2016

Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years.

Brain 2015 Nov 11;138(Pt 11):3386-99. Epub 2015 Aug 11.

1 National Prion Clinic, National Hospital for Neurology and Neurosurgery (NHNN), University College London (UCL) Hospitals NHS Foundation Trust, Queen Square, London WC1N 3BG, UK 2 MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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https://academic.oup.com/brain/article-lookup/doi/10.1093/br
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http://dx.doi.org/10.1093/brain/awv235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620512PMC
November 2015

Diagnostic, prognostic and predictive relevance of molecular markers in gliomas.

Neuropathol Appl Neurobiol 2015 Oct 10;41(6):694-720. Epub 2015 Jun 10.

Department of Neuropathology, University of Heidelberg, Heidelberg, Germany.

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http://doi.wiley.com/10.1111/nan.12246
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http://dx.doi.org/10.1111/nan.12246DOI Listing
October 2015

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy.

Nature 2015 Sep;525(7568):247-50

Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1038/nature15369DOI Listing
September 2015

Identification of clinical target areas in the brainstem of prion-infected mice.

Neuropathol Appl Neurobiol 2015 Aug 23;41(5):613-30. Epub 2015 Apr 23.

MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1111/nan.12189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949711PMC
August 2015

Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS.

PLoS Pathog 2015 Jul 2;11(7):e1004953. Epub 2015 Jul 2.

MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1004953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489887PMC
July 2015

A new functional classification system (FGA/B) with prognostic value for glioma patients.

Sci Rep 2015 Jul 21;5:12373. Epub 2015 Jul 21.

Department of Neurosurgery, Medical Faculty of the Friedrich Alexander University of Erlangen-Nürnberg (FAU).

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http://dx.doi.org/10.1038/srep12373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648469PMC
July 2015

Quantification of serial changes in cerebral blood volume and metabolism in patients with recurrent glioblastoma undergoing antiangiogenic therapy.

Eur J Radiol 2015 Jun 6;84(6):1128-36. Epub 2015 Mar 6.

Institute of Medical Radiology, University Clinic of St. Pölten, Propst Führer-Straße 4, A-3100 St. Pölten, Austria.

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http://dx.doi.org/10.1016/j.ejrad.2015.02.025DOI Listing
June 2015

MRI detection of prion protein plaques in variant Creutzfeldt-Jakob disease.

Neurology 2015 Apr;84(14):1498-9

From UCL Institute of Neurology (H.H., S.B., J.C., H.G.P.), London; and Kings College London (P.-W.S.), UK.

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http://dx.doi.org/10.1212/WNL.0000000000000304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395891PMC
April 2015

Ventricular and lumbar cerebrospinal fluid concentrations of Alzheimer's disease biomarkers in patients with normal pressure hydrocephalus and posttraumatic hydrocephalus.

J Alzheimers Dis 2014 ;41(4):1057-62

Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.3233/JAD-132708DOI Listing
March 2015

Plasma concentrations of the amyloid-β peptides in young volunteers: the influence of the APOE genotype.

J Alzheimers Dis 2014 ;40(4):1055-60

Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.3233/JAD-132687DOI Listing
January 2015

Supratentorial ependymoma presenting as a cortical cyst with a mural nodule in an adult.

J Surg Case Rep 2015 Jan 14;2015(1). Epub 2015 Jan 14.

Victor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, London, UK.

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http://jscr.oxfordjournals.org/content/jscr/2015/1/rju124.fu
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http://jscr.oxfordjournals.org/cgi/doi/10.1093/jscr/rju124
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http://dx.doi.org/10.1093/jscr/rju124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294457PMC
January 2015

Active and silent thyroid-stimulating hormone-expressing pituitary adenomas: presenting symptoms, treatment, outcomes, and recurrence.

World Neurosurg 2014 Dec 18;82(6):1224-31. Epub 2014 Mar 18.

Department of Endocrinology, University College London Hospital, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2014.03.031DOI Listing
December 2014

Truncating and missense mutations in IGHMBP2 cause Charcot-Marie Tooth disease type 2.

Am J Hum Genet 2014 Nov 30;95(5):590-601. Epub 2014 Oct 30.

MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK; Department of Molecular Neurosciences, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK; Neurogenetics Laboratory, The National Hospital for Neurology and Neurosurgery and UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225647PMC
November 2014

A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects.

PLoS One 2014 21;9(1):e85962. Epub 2014 Jan 21.

MRC Mammalian Genetics Unit, Harwell, Oxfordshire, United Kingdom ; Department of Neurodegenerative Diseases and MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085962PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897576PMC
October 2014

Extended phenotypic spectrum of KIF5A mutations: From spastic paraplegia to axonal neuropathy.

Neurology 2014 Aug 9;83(7):612-9. Epub 2014 Jul 9.

From the MRC Centre for Neuromuscular Diseases (Y.-T.L., M.L., A.H., M.M.R., H.H.) and Departments of Molecular Neuroscience (Y.-T.L., J.H., A.H., A.P., D.H., M.M.R., H.H.) and Clinical Neuroscience (C.P.), UCL Institute of Neurology; National Hospital for Neurology and Neurosurgery and UCLH (M.L., J.H., A.H., K.G.S., M.M.R., H.H.), London, UK; Section of Epilepsy (Y.-T.L.), Department of Neurology, Neurological Institute, Taipei Veterans General Hospital; National Yang-Ming University School of Medicine (Y.-T.L.), Taipei, Taiwan; Division of Neuropathology (Z.J., S.B.) and Neurogenetics Unit (J.M.P, M.G.S.), National Hospital for Neurology and Neurosurgery; Department of Neurology (J.C.J.), Chelsea and Westminster Hospital, London, UK; Department of Orthopaedics (M.A.-G.), Medical University Vienna, Austria; and Dr. John T. MacDonald Department of Human Genetics and Hussman Institute for Human Genomics (S.Z.), Miller School of Medicine, University of Miami, FL.

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http://www.neurology.org/content/83/7/612.full.pdf
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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000069
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http://dx.doi.org/10.1212/WNL.0000000000000691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141994PMC
August 2014

Nature has no principle-inflammation following brain injury is neither good nor evil*.

Crit Care Med 2014 Aug;42(8):1958-9

Department of Neurosurgery, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1097/CCM.0000000000000479DOI Listing
August 2014

A crucial role for DOK1 in PDGF-BB-stimulated glioma cell invasion through p130Cas and Rap1 signalling.

J Cell Sci 2014 Jun 24;127(Pt 12):2647-58. Epub 2014 Apr 24.

Centre for Cardiovascular Biology and Medicine, Division of Medicine, Rayne Building, University College London, London WC1E 6JJ, UK

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http://dx.doi.org/10.1242/jcs.135988DOI Listing
June 2014

High-throughput, automated quantification of white matter neurons in mild malformation of cortical development in epilepsy.

Acta Neuropathol Commun 2014 Jun 13;2:72. Epub 2014 Jun 13.

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, Queen Square, WC1N 3BG London, UK.

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http://dx.doi.org/10.1186/2051-5960-2-72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229809PMC
June 2014

Novel C12orf65 mutations in patients with axonal neuropathy and optic atrophy.

J Neurol Neurosurg Psychiatry 2014 May 6;85(5):486-92. Epub 2013 Nov 6.

Department of Molecular Neuroscience and Reta Lila Weston Research Laboratories, UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery, , London, UK.

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http://dx.doi.org/10.1136/jnnp-2013-306387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995331PMC
May 2014

Peripheral administration of a humanized anti-PrP antibody blocks Alzheimer's disease Aβ synaptotoxicity.

J Neurosci 2014 Apr;34(18):6140-5

Department of Pharmacology and Therapeutics and Institute of Neuroscience, Trinity College, Dublin 2, Republic of Ireland, Medical Research Council Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, London WC1N 3BG, United Kingdom, Laboratory for Neurodegenerative Research, Center for Neurologic Diseases, Brigham & Women's Hospital, Harvard Institute of Medicine, Boston, Massachusetts 02115, and Biotherapeutics Group, Medical Research Council Technology, Mill Hill, London, United Kingdom NW7 1AD.

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http://dx.doi.org/10.1523/JNEUROSCI.3526-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004804PMC
April 2014

Variant Creutzfeldt-Jakob disease with extremely low lymphoreticular deposition of prion protein.

JAMA Neurol 2014 Mar;71(3):340-3

National Prion Clinic, National Hospital for Neurology and Neurosurgery, Queen Square, London, England2Medical Research Council Prion Unit, Department of Neurodegenerative Disease, University College London Institute of Neurology, Queen Square, London, En.

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http://dx.doi.org/10.1001/jamaneurol.2013.5378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158717PMC
March 2014

Microglial Cx3cr1 knockout reduces prion disease incubation time in mice.

BMC Neurosci 2014 Mar 21;15:44. Epub 2014 Mar 21.

MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1186/1471-2202-15-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998043PMC
March 2014

White matter perivascular spaces: an MRI marker in pathology-proven cerebral amyloid angiopathy?

Neurology 2014 Jan 27;82(1):57-62. Epub 2013 Nov 27.

From the Stroke Research Group (A.C., D.J.W.), Division of Neuropathology and Department of Neurodegenerative Disease (Z.J., S.B.), and Lysholm Department of Neuroradiology (R.J.), UCL Institute of Neurology, London, UK; The National Hospital for Neurology and Neurosurgery (A.C., R.J., D.J.W.), London, UK; Department of Clinical Neurosciences (J.-C.B.) and Department of Pathology (J.X.), University of Cambridge, Addenbrooke's Hospital, Cambridge, UK; Department of Neuropathology (J.-C.B., P.V.), Hospital Sainte-Anne, Paris, France; University Paris Descartes (J.-C.B., P.V.), Paris, France; Biomedical Research Centre (M.B.), UCL, UK; and Department of Neurology (A.P.), Cliniques Universitaires UCL Saint Luc, Brussels, Belgium.

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http://dx.doi.org/10.1212/01.wnl.0000438225.02729.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873625PMC
January 2014

A novel prion disease associated with diarrhea and autonomic neuropathy.

N Engl J Med 2013 Nov;369(20):1904-14

Medical Research Council (MRC) Prion Unit (S.M., J.B., C.C., S.J., J.M.L., H.A.-D., B.S., M.K.S., S.B., J.D.F.W., J.C.), Department of Molecular Neuroscience (S.G., N.W.W.), and Dementia Research Centre, Department of Neurodegenerative Disease (J.D.W.), and MRC Centre for Neuromuscular Diseases (M.M.R.), University College London (UCL) Institute of Neurology; the National Prion Clinic (S.M., D.C., D.G., H.H., P.R., J.C.), National Hospital for Neurology and Neurosurgery (M.K.), UCL Hospitals National Health Service Trust (A.F.); and the Queen Square Brain Bank (H.A., T.L., T.R., J.L.H.) - all in London.

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http://dx.doi.org/10.1056/NEJMoa1214747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863770PMC
November 2013