Publications by authors named "Sebastian A Leidel"

35Publications

Modulation of Translation by the Specific Inactivation of tRNA Under Oxidative Stress.

Front Genet 2020 18;11:856. Epub 2020 Aug 18.

Programa de Biología Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile.

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http://dx.doi.org/10.3389/fgene.2020.00856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461829PMC
August 2020

PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs.

Sci Rep 2020 02 17;10(1):2758. Epub 2020 Feb 17.

Institute for Biochemistry, Westfälische-Wilhelms-Universität Münster, Wilhelm-Klemm-Str. 2, D-48149, Münster, Germany.

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http://dx.doi.org/10.1038/s41598-020-59678-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026441PMC
February 2020

The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin?

FEBS Lett 2019 07 27;593(13):1483-1493. Epub 2019 Jun 27.

Max Planck Research Group for RNA Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany.

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http://dx.doi.org/10.1002/1873-3468.13491DOI Listing
July 2019

Absolute Quantification of Noncoding RNA by Microscale Thermophoresis.

Angew Chem Int Ed Engl 2019 07 2;58(28):9565-9569. Epub 2019 May 2.

Institute of Pharmacy and Biochemistry, Johannes Gutenberg University Mainz, Staudingerweg 5, 55128, Mainz, Germany.

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http://dx.doi.org/10.1002/anie.201814377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617968PMC
July 2019

Matching tRNA modifications in humans to their known and predicted enzymes.

Nucleic Acids Res 2019 03;47(5):2143-2159

Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, ul. Trojdena 4, 02-109 Warsaw, Poland.

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http://dx.doi.org/10.1093/nar/gkz011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412123PMC
March 2019

The Uba4 domain interplay is mediated via a thioester that is critical for tRNA thiolation through Urm1 thiocarboxylation.

Nucleic Acids Res 2018 06;46(10):5171-5181

Max Planck Research Group for RNA Biology, Max Planck Institute for Molecular Biomedicine, Von-Esmarch-Strasse 54, 48149 Muenster, Germany.

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http://dx.doi.org/10.1093/nar/gky312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007339PMC
June 2018

Enzymatic or In Vivo Installation of Propargyl Groups in Combination with Click Chemistry for the Enrichment and Detection of Methyltransferase Target Sites in RNA.

Angew Chem Int Ed Engl 2018 05 22;57(21):6342-6346. Epub 2018 Mar 22.

Institute of Biochemistry, Department of Chemistry, University of Münster, Wilhelm-Klemm-Straße 2, 48149, Münster, Germany.

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http://dx.doi.org/10.1002/anie.201800188DOI Listing
May 2018

The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan.

Nat Commun 2017 09 6;8(1):457. Epub 2017 Sep 6.

Computational and Systems Biology, Biozentrum, University of Basel, Klingelbergstrasse 50-70, 4056, Basel, Switzerland.

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http://dx.doi.org/10.1038/s41467-017-00539-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587724PMC
September 2017

Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.

Authors:
Daniela A Braun Jia Rao Geraldine Mollet David Schapiro Marie-Claire Daugeron Weizhen Tan Olivier Gribouval Olivia Boyer Patrick Revy Tilman Jobst-Schwan Johanna Magdalena Schmidt Jennifer A Lawson Denny Schanze Shazia Ashraf Jeremy F P Ullmann Charlotte A Hoogstraten Nathalie Boddaert Bruno Collinet Gaëlle Martin Dominique Liger Svjetlana Lovric Monica Furlano I Chiara Guerrera Oraly Sanchez-Ferras Jennifer F Hu Anne-Claire Boschat Sylvia Sanquer Björn Menten Sarah Vergult Nina De Rocker Merlin Airik Tobias Hermle Shirlee Shril Eugen Widmeier Heon Yung Gee Won-Il Choi Carolin E Sadowski Werner L Pabst Jillian K Warejko Ankana Daga Tamara Basta Verena Matejas Karin Scharmann Sandra D Kienast Babak Behnam Brendan Beeson Amber Begtrup Malcolm Bruce Gaik-Siew Ch'ng Shuan-Pei Lin Jui-Hsing Chang Chao-Huei Chen Megan T Cho Patrick M Gaffney Patrick E Gipson Chyong-Hsin Hsu Jameela A Kari Yu-Yuan Ke Cathy Kiraly-Borri Wai-Ming Lai Emmanuelle Lemyre Rebecca Okashah Littlejohn Amira Masri Mastaneh Moghtaderi Kazuyuki Nakamura Fatih Ozaltin Marleen Praet Chitra Prasad Agnieszka Prytula Elizabeth R Roeder Patrick Rump Rhonda E Schnur Takashi Shiihara Manish D Sinha Neveen A Soliman Kenza Soulami David A Sweetser Wen-Hui Tsai Jeng-Daw Tsai Rezan Topaloglu Udo Vester David H Viskochil Nithiwat Vatanavicharn Jessica L Waxler Klaas J Wierenga Matthias T F Wolf Sik-Nin Wong Sebastian A Leidel Gessica Truglio Peter C Dedon Annapurna Poduri Shrikant Mane Richard P Lifton Maxime Bouchard Peter Kannu David Chitayat Daniella Magen Bert Callewaert Herman van Tilbeurgh Martin Zenker Corinne Antignac Friedhelm Hildebrandt

Nat Genet 2017 Oct 14;49(10):1529-1538. Epub 2017 Aug 14.

Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://www.nature.com/doifinder/10.1038/ng.3933
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http://dx.doi.org/10.1038/ng.3933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819591PMC
October 2017

pyQms enables universal and accurate quantification of mass spectrometry data.

Mol Cell Proteomics 2017 10 20;16(10):1736-1745. Epub 2017 Jul 20.

From the ‡Institute of Plant Biology and Biotechnology, University of Muenster, Schlossplatz 8, 48143 Muenster, Germany;

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http://dx.doi.org/10.1074/mcp.M117.068007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629261PMC
October 2017

Wobble uridine modifications-a reason to live, a reason to die?!

RNA Biol 2017 09 23;14(9):1209-1222. Epub 2017 Feb 23.

b Max Planck Institute for Molecular Biomedicine , Germany.

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http://dx.doi.org/10.1080/15476286.2017.1295204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699542PMC
September 2017

A novel translational control mechanism involving RNA structures within coding sequences.

Genome Res 2017 01 7;27(1):95-106. Epub 2016 Nov 7.

Molecular Virology Group, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1101/gr.209015.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204348PMC
January 2017

Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

Plant Physiol 2016 10 8;172(2):858-873. Epub 2016 Aug 8.

Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium (S.I., A.N.D., A.R., S.L.G., B.D.C., J.V.L., R.D.C., B.P.A.C., G.D.J., M.V.L., L.P., A.G.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium (S.I., A.N.D., A.R., S.L.G., J.V.L., R.D.C., G.D.J., M.V.L., L.P., A.G.);Max Planck Research Group for RNA Biology, Max Planck Institute for Molecular Biomedicine, 48149 Muenster, Germany (M.T., S.A.L.);Institut für Biologie, Fachgebiet Mikrobiologie, Universität Kassel, D-34132 Kassel, Germany (R.K., R.S.);Max Planck Institute of Molecular Plant Physiology, D-14476 Potsdam-Golm, Germany (T.T., A.R.F.);Centre of Microbial and Plant Genetics, Katholieke Universiteit Leuven, B-3001 Leuven, Belgium (B.D.C., B.P.A.C.);Cells-in-Motion Cluster of Excellence (M.T., S.A.L.) and Faculty of Medicine (S.A.L.), University of Muenster, 48149 Muenster, Germany;Department of Medical Protein Research, VIB, B-9000 Ghent, Belgium (K.G.); andDepartment of Biochemistry, Ghent University, B-9000 Ghent, Belgium (K.G.)

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047072PMC
http://dx.doi.org/10.1104/pp.16.00261DOI Listing
October 2016

Dual randomization of oligonucleotides to reduce the bias in ribosome-profiling libraries.

Methods 2016 09 19;107:89-97. Epub 2016 Jul 19.

Max Planck Research Group for RNA Biology, Max Planck Institute for Molecular Biomedicine, Von-Esmarch-Strasse 54, 48149 Muenster, Germany; Muenster Graduate School of Evolution, University of Muenster, 48149 Muenster, Germany; Cells-in-Motion Cluster of Excellence, University of Muenster, 48149 Muenster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2016.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024760PMC
September 2016

A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis.

Dev Cell 2015 Dec;35(5):553-567

GIGA-Neurosciences, University of Liège, C.H.U. Sart Tilman, Liège 4000, Belgium; Interdisciplinary Cluster for Applied Genoproteomics (GIGA-R), University of Liège, C.H.U. Sart Tilman, Liège 4000, Belgium; Walloon Excellence in Lifesciences and Biotechnology (WELBIO), University of Liège, C.H.U. Sart Tilman, Liège 4000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.11.005DOI Listing
December 2015

Structures to the people!

Elife 2015 Jul 8;4:e09249. Epub 2015 Jul 8.

RNA Biology Laboratory, University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.7554/eLife.09249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495715PMC
July 2015

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity.

Cell 2015 Jun 4;161(7):1606-18. Epub 2015 Jun 4.

Max Planck Research Group for RNA Biology, Max Planck Institute for Molecular Biomedicine, Von-Esmarch-Strasse 54, 48149 Muenster, Germany; Cells-in-Motion Cluster of Excellence, University of Muenster, 48149 Muenster, Germany; Faculty of Medicine, University of Muenster, Albert-Schweitzer-Campus 1, 48149 Muenster, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674150057
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http://dx.doi.org/10.1016/j.cell.2015.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503807PMC
June 2015

Modify or die?--RNA modification defects in metazoans.

RNA Biol 2014 ;11(12):1555-67

a Max Planck Institute for Molecular Biomedicine ; Münster , Germany.

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http://dx.doi.org/10.4161/15476286.2014.992279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615230PMC
October 2015

An evolutionary approach uncovers a diverse response of tRNA 2-thiolation to elevated temperatures in yeast.

RNA 2015 Feb 12;21(2):202-12. Epub 2014 Dec 12.

RNA Biology Laboratory, Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany Faculty of Medicine, University of Münster, 48149 Münster, Germany

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http://dx.doi.org/10.1261/rna.048199.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338348PMC
February 2015