Sean P Curtis

Sean P Curtis

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Sean P Curtis

Sean P Curtis

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Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.

Authors:
Vinicius Tragante Michael R Barnes Santhi K Ganesh Matthew B Lanktree Wei Guo Nora Franceschini Erin N Smith Toby Johnson Michael V Holmes Sandosh Padmanabhan Konrad J Karczewski Berta Almoguera John Barnard Jens Baumert Yen-Pei Christy Chang Clara C Elbers Martin Farrall Mary E Fischer Tom R Gaunt Johannes M I H Gho Christian Gieger Anuj Goel Yan Gong Aaron Isaacs Marcus E Kleber Irene Mateo Leach Caitrin W McDonough Matthijs F L Meijs Olle Melander Christopher P Nelson Ilja M Nolte Nathan Pankratz Tom S Price Jonathan Shaffer Sonia Shah Maciej Tomaszewski Peter J van der Most Erik P A Van Iperen Judith M Vonk Kate Witkowska Caroline O L Wong Li Zhang Amber L Beitelshees Gerald S Berenson Deepak L Bhatt Morris Brown Amber Burt Rhonda M Cooper-DeHoff John M Connell Karen J Cruickshanks Sean P Curtis George Davey-Smith Christian Delles Ron T Gansevoort Xiuqing Guo Shen Haiqing Claire E Hastie Marten H Hofker G Kees Hovingh Daniel S Kim Susan A Kirkland Barbara E Klein Ronald Klein Yun R Li Steffi Maiwald Christopher Newton-Cheh Eoin T O'Brien N Charlotte Onland-Moret Walter Palmas Afshin Parsa Brenda W Penninx Mary Pettinger Ramachandran S Vasan Jane E Ranchalis Paul M Ridker Lynda M Rose Peter Sever Daichi Shimbo Laura Steele Ronald P Stolk Barbara Thorand Mieke D Trip Cornelia M van Duijn W Monique Verschuren Cisca Wijmenga Sharon Wyatt J Hunter Young Aeilko H Zwinderman Connie R Bezzina Eric Boerwinkle Juan P Casas Mark J Caulfield Aravinda Chakravarti Daniel I Chasman Karina W Davidson Pieter A Doevendans Anna F Dominiczak Garret A FitzGerald John G Gums Myriam Fornage Hakon Hakonarson Indrani Halder Hans L Hillege Thomas Illig Gail P Jarvik Julie A Johnson John J P Kastelein Wolfgang Koenig Meena Kumari Winfried März Sarah S Murray Jeffery R O'Connell Albertine J Oldehinkel James S Pankow Daniel J Rader Susan Redline Muredach P Reilly Eric E Schadt Kandice Kottke-Marchant Harold Snieder Michael Snyder Alice V Stanton Martin D Tobin André G Uitterlinden Pim van der Harst Yvonne T van der Schouw Nilesh J Samani Hugh Watkins Andrew D Johnson Alex P Reiner Xiaofeng Zhu Paul I W de Bakker Daniel Levy Folkert W Asselbergs Patricia B Munroe Brendan J Keating

Am J Hum Genet 2014 Mar 20;94(3):349-60. Epub 2014 Feb 20.

Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2013.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951943PMC
March 2014

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.

Am J Hum Genet 2014 Feb 23;94(2):198-208. Epub 2014 Jan 23.

Division of Transplantation, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA; Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2013.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928659PMC
February 2014

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

Authors:
Santhi K Ganesh Vinicius Tragante Wei Guo Yiran Guo Matthew B Lanktree Erin N Smith Toby Johnson Berta Almoguera Castillo John Barnard Jens Baumert Yen-Pei Christy Chang Clara C Elbers Martin Farrall Mary E Fischer Nora Franceschini Tom R Gaunt Johannes M I H Gho Christian Gieger Yan Gong Aaron Isaacs Marcus E Kleber Irene Mateo Leach Caitrin W McDonough Matthijs F L Meijs Olle Mellander Cliona M Molony Ilja M Nolte Sandosh Padmanabhan Tom S Price Ramakrishnan Rajagopalan Jonathan Shaffer Sonia Shah Haiqing Shen Nicole Soranzo Peter J van der Most Erik P A Van Iperen Jessica Van Setten Jessic A Van Setten Judith M Vonk Li Zhang Amber L Beitelshees Gerald S Berenson Deepak L Bhatt Jolanda M A Boer Eric Boerwinkle Ben Burkley Amber Burt Aravinda Chakravarti Wei Chen Rhonda M Cooper-Dehoff Sean P Curtis Albert Dreisbach David Duggan Georg B Ehret Richard R Fabsitz Myriam Fornage Ervin Fox Clement E Furlong Ron T Gansevoort Marten H Hofker G Kees Hovingh Susan A Kirkland Kandice Kottke-Marchant Abdullah Kutlar Andrea Z Lacroix Taimour Y Langaee Yun R Li Honghuang Lin Kiang Liu Steffi Maiwald Rainer Malik Gurunathan Murugesan Christopher Newton-Cheh Jeffery R O'Connell N Charlotte Onland-Moret Willem H Ouwehand Walter Palmas Brenda W Penninx Carl J Pepine Mary Pettinger Joseph F Polak Vasan S Ramachandran Jane Ranchalis Susan Redline Paul M Ridker Lynda M Rose Hubert Scharnag Nicholas J Schork Daichi Shimbo Alan R Shuldiner Sathanur R Srinivasan Ronald P Stolk Herman A Taylor Barbara Thorand Mieke D Trip Cornelia M van Duijn W Monique Verschuren Cisca Wijmenga Bernhard R Winkelmann Sharon Wyatt J Hunter Young Bernhard O Boehm Mark J Caulfield Daniel I Chasman Karina W Davidson Pieter A Doevendans Garret A Fitzgerald John G Gums Hakon Hakonarson Hans L Hillege Thomas Illig Gail P Jarvik Julie A Johnson John J P Kastelein Wolfgang Koenig Winfried März Braxton D Mitchell Sarah S Murray Albertine J Oldehinkel Daniel J Rader Muredach P Reilly Alex P Reiner Eric E Schadt Roy L Silverstein Harold Snieder Alice V Stanton André G Uitterlinden Pim van der Harst Yvonne T van der Schouw Nilesh J Samani Andrew D Johnson Patricia B Munroe Paul I W de Bakker Xiaofeng Zhu Daniel Levy Brendan J Keating Folkert W Asselbergs

Hum Mol Genet 2013 Apr 8;22(8):1663-78. Epub 2013 Jan 8.

Division of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, MI, USA.

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http://hmg.oxfordjournals.org/content/22/8/1663.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/dds555
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http://dx.doi.org/10.1093/hmg/dds555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657476PMC
April 2013

Blood pressure and cardiovascular outcomes in patients taking nonsteroidal antiinflammatory drugs.

Cardiovasc Ther 2012 Dec 25;30(6):342-50. Epub 2011 May 25.

Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1111/j.1755-5922.2011.00283.xDOI Listing
December 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.

Authors:
Richa Saxena Clara C Elbers Yiran Guo Inga Peter Tom R Gaunt Jessica L Mega Matthew B Lanktree Archana Tare Berta Almoguera Castillo Yun R Li Toby Johnson Marcel Bruinenberg Diane Gilbert-Diamond Ramakrishnan Rajagopalan Benjamin F Voight Ashok Balasubramanyam John Barnard Florianne Bauer Jens Baumert Tushar Bhangale Bernhard O Böhm Peter S Braund Paul R Burton Hareesh R Chandrupatla Robert Clarke Rhonda M Cooper-DeHoff Errol D Crook George Davey-Smith Ian N Day Anthonius de Boer Mark C H de Groot Fotios Drenos Jane Ferguson Caroline S Fox Clement E Furlong Quince Gibson Christian Gieger Lisa A Gilhuijs-Pederson Joseph T Glessner Anuj Goel Yan Gong Struan F A Grant Diederick E Grobbee Claire Hastie Steve E Humphries Cecilia E Kim Mika Kivimaki Marcus Kleber Christa Meisinger Meena Kumari Taimour Y Langaee Debbie A Lawlor Mingyao Li Maximilian T Lobmeyer Anke-Hilse Maitland-van der Zee Matthijs F L Meijs Cliona M Molony David A Morrow Gurunathan Murugesan Solomon K Musani Christopher P Nelson Stephen J Newhouse Jeffery R O'Connell Sandosh Padmanabhan Jutta Palmen Sanjey R Patel Carl J Pepine Mary Pettinger Thomas S Price Suzanne Rafelt Jane Ranchalis Asif Rasheed Elisabeth Rosenthal Ingo Ruczinski Sonia Shah Haiqing Shen Günther Silbernagel Erin N Smith Annemieke W M Spijkerman Alice Stanton Michael W Steffes Barbara Thorand Mieke Trip Pim van der Harst Daphne L van der A Erik P A van Iperen Jessica van Setten Jana V van Vliet-Ostaptchouk Niek Verweij Bruce H R Wolffenbuttel Taylor Young M Hadi Zafarmand Joseph M Zmuda Michael Boehnke David Altshuler Mark McCarthy W H Linda Kao James S Pankow Thomas P Cappola Peter Sever Neil Poulter Mark Caulfield Anna Dominiczak Denis C Shields Deepak L Bhatt Deepak Bhatt Li Zhang Sean P Curtis John Danesh Juan P Casas Yvonne T van der Schouw N Charlotte Onland-Moret Pieter A Doevendans Gerald W Dorn Martin Farrall Garret A FitzGerald Anders Hamsten Robert Hegele Aroon D Hingorani Marten H Hofker Gordon S Huggins Thomas Illig Gail P Jarvik Julie A Johnson Olaf H Klungel William C Knowler Wolfgang Koenig Winfried März James B Meigs Olle Melander Patricia B Munroe Braxton D Mitchell Susan J Bielinski Daniel J Rader Muredach P Reilly Stephen S Rich Jerome I Rotter Danish Saleheen Nilesh J Samani Eric E Schadt Alan R Shuldiner Roy Silverstein Kandice Kottke-Marchant Philippa J Talmud Hugh Watkins Folkert W Asselbergs Folkert Asselbergs Paul I W de Bakker Jeanne McCaffery Cisca Wijmenga Marc S Sabatine James G Wilson Alex Reiner Donald W Bowden Hakon Hakonarson David S Siscovick Brendan J Keating

Am J Hum Genet 2012 Mar 9;90(3):410-25. Epub 2012 Feb 9.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, 02114, USA.

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http://dx.doi.org/10.1016/j.ajhg.2011.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309185PMC
March 2012

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Authors:
Matthew B Lanktree Yiran Guo Muhammed Murtaza Joseph T Glessner Swneke D Bailey N Charlotte Onland-Moret Guillaume Lettre Halit Ongen Ramakrishnan Rajagopalan Toby Johnson Haiqing Shen Christopher P Nelson Norman Klopp Jens Baumert Sandosh Padmanabhan Nathan Pankratz James S Pankow Sonia Shah Kira Taylor John Barnard Bas J Peters Cliona M Maloney Maximilian T Lobmeyer Alice Stanton M Hadi Zafarmand Simon P R Romaine Amar Mehta Erik P A van Iperen Yan Gong Tom S Price Erin N Smith Cecilia E Kim Yun R Li Folkert W Asselbergs Larry D Atwood Kristian M Bailey Deepak Bhatt Florianne Bauer Elijah R Behr Tushar Bhangale Jolanda M A Boer Bernhard O Boehm Jonathan P Bradfield Morris Brown Peter S Braund Paul R Burton Cara Carty Hareesh R Chandrupatla Wei Chen John Connell Chrysoula Dalgeorgou Anthonius de Boer Fotios Drenos Clara C Elbers James C Fang Caroline S Fox Edward C Frackelton Barry Fuchs Clement E Furlong Quince Gibson Christian Gieger Anuj Goel Diederik E Grobbee Claire Hastie Philip J Howard Guan-Hua Huang W Craig Johnson Qing Li Marcus E Kleber Barbara E K Klein Ronald Klein Charles Kooperberg Bonnie Ky Andrea Lacroix Paul Lanken Mark Lathrop Mingyao Li Vanessa Marshall Olle Melander Frank D Mentch Nuala J Meyer Keri L Monda Alexandre Montpetit Gurunathan Murugesan Karen Nakayama Dave Nondahl Abiodun Onipinla Suzanne Rafelt Stephen J Newhouse F George Otieno Sanjey R Patel Mary E Putt Santiago Rodriguez Radwan N Safa Douglas B Sawyer Pamela J Schreiner Claire Simpson Suthesh Sivapalaratnam Sathanur R Srinivasan Christine Suver Gary Swergold Nancy K Sweitzer Kelly A Thomas Barbara Thorand Nicholas J Timpson Sam Tischfield Martin Tobin Maciej Tomaszewski Maciej Tomaszweski W M Monique Verschuren Chris Wallace Bernhard Winkelmann Haitao Zhang Dongling Zheng Li Zhang Joseph M Zmuda Robert Clarke Anthony J Balmforth John Danesh Ian N Day Nicholas J Schork Paul I W de Bakker Christian Delles David Duggan Aroon D Hingorani Joel N Hirschhorn Marten H Hofker Steve E Humphries Mika Kivimaki Debbie A Lawlor Kandice Kottke-Marchant Jessica L Mega Braxton D Mitchell David A Morrow Jutta Palmen Susan Redline Denis C Shields Alan R Shuldiner Patrick M Sleiman George Davey Smith Martin Farrall Yalda Jamshidi David C Christiani Juan P Casas Alistair S Hall Pieter A Doevendans Jason D Christie Gerald S Berenson Sarah S Murray Thomas Illig Gerald W Dorn Thomas P Cappola Eric Boerwinkle Peter Sever Daniel J Rader Muredach P Reilly Mark Caulfield Philippa J Talmud Eric Topol James C Engert Kai Wang Anna Dominiczak Anders Hamsten Sean P Curtis Roy L Silverstein Leslie A Lange Marc S Sabatine Mieke Trip Danish Saleheen John F Peden Karen J Cruickshanks Winfried März Jeffrey R O'Connell Olaf H Klungel Cisca Wijmenga Anke Hilse Maitland-van der Zee Eric E Schadt Julie A Johnson Gail P Jarvik George J Papanicolaou Struan F A Grant Patricia B Munroe Kari E North Nilesh J Samani Wolfgang Koenig Tom R Gaunt Sonia S Anand Yvonne T van der Schouw Nicole Soranzo Garret A Fitzgerald Alex Reiner Robert A Hegele Hakon Hakonarson Brendan J Keating

Am J Hum Genet 2011 Jan 30;88(1):6-18. Epub 2010 Dec 30.

Department of Medicine and Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.

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http://dx.doi.org/10.1016/j.ajhg.2010.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014369PMC
January 2011

Baseline factors associated with congestive heart failure in patients receiving etoricoxib or diclofenac: multivariate analysis of the MEDAL program.

Eur J Heart Fail 2009 Jun 19;11(6):542-50. Epub 2009 Apr 19.

Department of Epidemiology and Preventive Medicine, NHMRC Centre of Clinical Research Excellence in Therapeutics, Monash University, Alfred Hospital, Melbourne Vic 3004, Australia.

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http://dx.doi.org/10.1093/eurjhf/hfp054DOI Listing
June 2009

Factors associated with blood pressure changes in patients receiving diclofenac or etoricoxib: results from the MEDAL study.

J Hypertens 2009 Apr;27(4):886-93

Department of Epidemiology and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1097/HJH.0b013e328325d831DOI Listing
April 2009

How common is diclofenac-associated liver injury? Analysis of 17,289 arthritis patients in a long-term prospective clinical trial.

Am J Gastroenterol 2009 Feb 27;104(2):356-62. Epub 2009 Jan 27.

University of Southern California, Los Angeles, California 90033, USA.

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http://dx.doi.org/10.1038/ajg.2008.149DOI Listing
February 2009

Lower gastrointestinal events in a double-blind trial of the cyclo-oxygenase-2 selective inhibitor etoricoxib and the traditional nonsteroidal anti-inflammatory drug diclofenac.

Gastroenterology 2008 Nov 3;135(5):1517-25. Epub 2008 Aug 3.

Division of Gastrointestinal & Liver Diseases, University of Southern California, Keck School of Medicine, Los Angeles, California, USA.

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http://dx.doi.org/10.1053/j.gastro.2008.07.067DOI Listing
November 2008

Etoricoxib versus naproxen in patients with rheumatoid arthritis: a prospective, randomized, comparator-controlled 121-week trial.

Curr Med Res Opin 2007 Sep;23(9):2259-68

Arthritis and Rheumatism Associates, Wheaton, MD, USA.

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http://dx.doi.org/10.1185/030079907X219625DOI Listing
September 2007

Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.

Lancet 2007 Feb;369(9560):465-73

Division of Gastrointestinal and Liver Diseases, Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1016/S0140-6736(07)60234-7DOI Listing
February 2007

Pooled analysis of thrombotic cardiovascular events in clinical trials of the COX-2 selective Inhibitor etoricoxib.

Curr Med Res Opin 2006 Dec;22(12):2365-74

Merck Research Laboratories, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1185/030079906x148238DOI Listing
December 2006

Clinical trial design and patient demographics of the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) study program: cardiovascular outcomes with etoricoxib versus diclofenac in patients with osteoarthritis and rheumatoid arthritis.

Am Heart J 2006 Aug;152(2):237-45

The TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ahj.2006.05.024DOI Listing
August 2006

Evaluation of the efficacy and safety of etoricoxib in the treatment of hemophilic arthropathy.

Blood 2006 Mar 15;107(5):1785-90. Epub 2005 Nov 15.

McGill University Health Centre, Montreal General Hospital, 1650 Cedar Ave, Rm A5-140, Montreal, QC H3G 1A4, Canada.

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http://dx.doi.org/10.1182/blood-2004-09-3501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895698PMC
March 2006

Renal effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs in controlled clinical trials.

Clin Ther 2004 Jan;26(1):70-83

Department of Clinical Research, Merck Research Laboratories, Rahway, New Jersey 07065, USA.

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http://dx.doi.org/10.1016/s0149-2918(04)90007-0DOI Listing
January 2004