Scott T Weiss

Scott T Weiss

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Integrative analysis of the intestinal metabolome of childhood asthma.

J Allergy Clin Immunol 2019 Aug 23;144(2):442-454. Epub 2019 Mar 23.

Division of Pediatric Pulmonary Medicine, Golisano Children's Hospital at Strong, University of Rochester Medical Center, Rochester, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.02.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688902PMC
August 2019

Fish-oil supplementation in pregnancy, child metabolomics and asthma risk.

EBioMedicine 2019 Aug 6;46:399-410. Epub 2019 Aug 6.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.07.057DOI Listing
August 2019

Network Diffusion Approach to Predict LncRNA Disease Associations Using Multi-Type Biological Networks: LION.

Front Physiol 2019 16;10:888. Epub 2019 Jul 16.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.3389/fphys.2019.00888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646690PMC
July 2019

Epigenetic age acceleration is associated with allergy and asthma in children in Project Viva.

J Allergy Clin Immunol 2019 Jun 6;143(6):2263-2270.e14. Epub 2019 Feb 6.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2019.01.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556426PMC
June 2019

Pathway analysis of a genome-wide gene by air pollution interaction study in asthmatic children.

J Expo Sci Environ Epidemiol 2019 Jun 26;29(4):539-547. Epub 2019 Apr 26.

Channing Division of Network Medicine, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.1038/s41370-019-0136-3DOI Listing
June 2019

DNA methylation is associated with inhaled corticosteroid response in persistent childhood asthmatics.

Clin Exp Allergy 2019 Jun 12. Epub 2019 Jun 12.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/cea.13447DOI Listing
June 2019

Fish oil supplementation during pregnancy is protective against asthma/wheeze in offspring.

J Allergy Clin Immunol Pract 2019 Jun 19. Epub 2019 Jun 19.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2019.05.054DOI Listing
June 2019

Remission of persistent childhood asthma: Early predictors of adult outcomes.

J Allergy Clin Immunol 2019 May 14;143(5):1752-1759.e6. Epub 2018 Nov 14.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183159
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http://dx.doi.org/10.1016/j.jaci.2018.09.038DOI Listing
May 2019

Maternal Asthma, Preeclampsia and Risk of Childhood Asthma at Age Six.

Am J Respir Crit Care Med 2019 May 6. Epub 2019 May 6.

Brigham and Women's Hospital Department of Medicine, 370908, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1164/rccm.201901-0081LEDOI Listing
May 2019

Impact of parental asthma, prenatal maternal asthma control, and vitamin D status on risk of asthma and recurrent wheeze in 3-year-old children.

Clin Exp Allergy 2019 Apr 3;49(4):419-429. Epub 2019 Jan 3.

Division of Pediatric Pulmonary Medicine, Department of Pediatrics, Golisano Children's Hospital at Strong, University of Rochester Medical Center, Rochester, New York.

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http://dx.doi.org/10.1111/cea.13320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438751PMC
April 2019

Gut microbiota and overweight in 3-year old children.

Int J Obes (Lond) 2019 Apr 19;43(4):713-723. Epub 2018 Dec 19.

Division of Pediatric Pulmonary Medicine, Department of Pediatrics, Golisano Children's Hospital at Strong, University of Rochester Medical Center, Rochester, New York, NY, USA.

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http://www.nature.com/articles/s41366-018-0290-z
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http://dx.doi.org/10.1038/s41366-018-0290-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457121PMC
April 2019

Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults.

J Allergy Clin Immunol 2019 Apr 20;143(4):1633-1635. Epub 2018 Dec 20.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; PRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Mass. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183277
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http://dx.doi.org/10.1016/j.jaci.2018.11.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451881PMC
April 2019

Network Medicine in the Age of Biomedical Big Data.

Front Genet 2019 11;10:294. Epub 2019 Apr 11.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, United States.

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http://dx.doi.org/10.3389/fgene.2019.00294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470635PMC
April 2019

An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.

J Allergy Clin Immunol 2019 Mar 7;143(3):957-969. Epub 2018 Sep 7.

Program in Pharmaceutical Sciences and Pharmacogenomics, University of California, San Francisco, San Francisco, Calif; Department of Bioengineering & Therapeutic Sciences, University of California, San Francisco, San Francisco, Calif; Department of Medicine, University of California, San Francisco, San Francisco, Calif.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183127
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http://dx.doi.org/10.1016/j.jaci.2016.08.057DOI Listing
March 2019

Metabolomics and Communication Skills Development in Children; Evidence from the Ages and Stages Questionnaire.

Metabolites 2019 Mar 5;9(3). Epub 2019 Mar 5.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.3390/metabo9030042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468693PMC
March 2019

Novel Data Transformations for RNA-seq Differential Expression Analysis.

Sci Rep 2019 Mar 18;9(1):4820. Epub 2019 Mar 18.

Channing Division of Network Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1038/s41598-019-41315-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423143PMC
March 2019

Expression network analysis reveals cord blood vitamin D-associated genes affecting risk of early life wheeze.

Thorax 2019 02 18;74(2):200-202. Epub 2018 Jul 18.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/thoraxjnl-2018-211962DOI Listing
February 2019

Dietary and Plasma Polyunsaturated Fatty Acids Are Inversely Associated with Asthma and Atopy in Early Childhood.

J Allergy Clin Immunol Pract 2019 Feb 24;7(2):529-538.e8. Epub 2018 Aug 24.

Division of Pediatric Pulmonary Medicine, Golisano Children's Hospital at University of Rochester Medical Center, Rochester, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2018.07.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400588PMC
February 2019

Impact of Preeclampsia on the Relationship between Maternal Asthma and Offspring Asthma. An Observation from the VDAART Clinical Trial.

Am J Respir Crit Care Med 2019 Jan;199(1):32-42

1 Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201804-0770OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353019PMC
January 2019

Deep Learning Methods for Predicting Disease Status Using Genomic Data.

J Biom Biostat 2018 11;9(5). Epub 2018 Dec 11.

Channing Division of Network Medicine, Brigham and Women's Hospital/Harvard Medical School, 181 Longwood Avenue, Boston MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530791PMC
December 2018

Novel eosinophilic gene expression networks associated with IgE in two distinct asthma populations.

Clin Exp Allergy 2018 Dec 21;48(12):1654-1664. Epub 2018 Nov 21.

Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1111/cea.13249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659730PMC
December 2018

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.

J Allergy Clin Immunol 2018 Nov 9;142(5):1469-1478.e2. Epub 2018 Jan 9.

Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037620PMC
November 2018

The phosphatidylinositide 3-kinase (PI3K) signaling pathway is a determinant of zileuton response in adults with asthma.

Pharmacogenomics J 2018 09 3;18(5):665-677. Epub 2018 Jan 3.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41397-017-0006-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150906PMC
September 2018

Association between aspirin dose and subarachnoid hemorrhage from saccular aneurysms: A case-control study.

Neurology 2018 09 22;91(12):e1175-e1181. Epub 2018 Aug 22.

From the Department of Neurosurgery (A.C., R.F.R., R.D.), Brigham and Women's Hospital, Harvard Medical School; Research Information Systems and Computing (V.M.C., V.G., S.M.); Department of Medicine (S.Y., S.T.W.), Division of Rheumatology, Immunology and Allergy (N.A.S.), and Channing Division of Network Medicine (S.T.W., R.D.), Brigham and Women's Hospital, Boston, MA; Center for Statistical Science (S.Y.), Tsinghua University, Beijing, China; Boston Children's Hospital Informatics Program (D.D., S.F., G.S.), MA; Department of Computer Science (D.D.), Loyola University, Chicago, IL; Department of Neurology (S.M.), Massachusetts General Hospital; and Biostatistics (T.C.), Harvard T.H. Chan School of Public Health, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000006200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161553PMC
September 2018

Elevated International Normalized Ratio Is Associated With Ruptured Aneurysms.

Stroke 2018 Sep;49(9):2046-2052

From the Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.C., R.D.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205738PMC
September 2018

Heroin Use Is Associated with Ruptured Saccular Aneurysms.

Transl Stroke Res 2018 08 4;9(4):340-346. Epub 2017 Nov 4.

Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1007/s12975-017-0582-yDOI Listing
August 2018

An Integrative Transcriptomic and Metabolomic Study of Lung Function in Children With Asthma.

Chest 2018 Aug 13;154(2):335-348. Epub 2018 Jun 13.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.chest.2018.05.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689076PMC
August 2018

Prenatal and early-life triclosan and paraben exposure and allergic outcomes.

J Allergy Clin Immunol 2018 07 27;142(1):269-278.e15. Epub 2017 Oct 27.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2017.09.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924494PMC
July 2018

Low Serum Calcium and Magnesium Levels and Rupture of Intracranial Aneurysms.

Stroke 2018 07 29;49(7):1747-1750. Epub 2018 May 29.

From the Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (A.C., R.F.R., R.D.)

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http://dx.doi.org/10.1161/STROKEAHA.118.020963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019530PMC
July 2018

Detecting Differentially Variable MicroRNAs via Model-Based Clustering.

Int J Genomics 2018 12;2018:6591634. Epub 2018 Jul 12.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1155/2018/6591634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079429PMC
July 2018

Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus.

J Allergy Clin Immunol 2018 06 31;141(6):2282-2286.e6. Epub 2018 Jan 31.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; Pulmonary Genetics Center and Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2017.11.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994185PMC
June 2018

A systems immunology approach identifies the collective impact of 5 miRs in Th2 inflammation.

JCI Insight 2018 Jun 7;3(11). Epub 2018 Jun 7.

Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University Marburg, Marburg, Germany.

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http://dx.doi.org/10.1172/jci.insight.97503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124409PMC
June 2018

A Nasal Brush-based Classifier of Asthma Identified by Machine Learning Analysis of Nasal RNA Sequence Data.

Sci Rep 2018 Jun 11;8(1):8826. Epub 2018 Jun 11.

Icahn Institute for Genomics and Multiscale Biology and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41598-018-27189-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995932PMC
June 2018

Circulating microRNAs and prediction of asthma exacerbation in childhood asthma.

Respir Res 2018 06 26;19(1):128. Epub 2018 Jun 26.

Channing Division of Network Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s12931-018-0828-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020199PMC
June 2018

Alcohol Consumption and Aneurysmal Subarachnoid Hemorrhage.

Transl Stroke Res 2018 02 27;9(1):13-19. Epub 2017 Jul 27.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s12975-017-0557-zDOI Listing
February 2018

Reply.

J Allergy Clin Immunol 2018 02 21;141(2):829-830. Epub 2017 Nov 21.

Division of Pediatric Pulmonary Medicine, Department of Pediatrics, Golisano Children's Hospital at Strong, University of Rochester Medical Center, Rochester, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.08.035DOI Listing
February 2018

Vitamin D supplementation during pregnancy: Effect on the neonatal immune system in a randomized controlled trial.

J Allergy Clin Immunol 2018 01 26;141(1):269-278.e1. Epub 2017 May 26.

MRC and Asthma UK Centre for Allergic Mechanisms in Asthma, King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.02.039DOI Listing
January 2018

Antihyperglycemic Agents Are Inversely Associated With Intracranial Aneurysm Rupture.

Stroke 2018 01 4;49(1):34-39. Epub 2017 Dec 4.

From the Department of Neurosurgery (A.C., R.D.), Department of Medicine (S.Y., S.T.W.), Division of Rheumatology, Immunology, and Allergy (N.A.S.), and Channing Division of Network Medicine (S.T.W., R.D.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Research Information Systems and Computing, Partners Healthcare, Boston, MA (V.M.C., V.G., S.M.); Center for Statistical Science, Tsinghua University, Beijing, China (S.Y.); Computational Health Informatics Program, Boston Children's Hospital, MA (D.D., S.F., G.S.); Department of Computer Science, Loyola University, Chicago, IL (D.D.); Department of Neurology, Massachusetts General Hospital, Boston (S.M.); and Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA (T.C.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019249DOI Listing
January 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Emerging mechanisms and novel targets in allergic inflammation and asthma.

Authors:
Scott T Weiss

Genome Med 2017 12 4;9(1):107. Epub 2017 Dec 4.

Harvard Medical School and Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s13073-017-0501-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713157PMC
December 2017

Mapping the ecological networks of microbial communities.

Nat Commun 2017 12 11;8(1):2042. Epub 2017 Dec 11.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1038/s41467-017-02090-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725606PMC
December 2017

Vitamin D supplementation in pregnancy, prenatal 25(OH)D levels, race, and subsequent asthma or recurrent wheeze in offspring: Secondary analyses from the Vitamin D Antenatal Asthma Reduction Trial.

J Allergy Clin Immunol 2017 Nov 9;140(5):1423-1429.e5. Epub 2017 Mar 9.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.01.013DOI Listing
November 2017

Asthma control status in pregnancy, body mass index, and maternal vitamin D levels.

J Allergy Clin Immunol 2017 11 9;140(5):1453-1456.e7. Epub 2017 Jun 9.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.03.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708874PMC
November 2017

Early pregnancy intrauterine fetal exposure to maternal smoking and impact on fetal telomere length.

Eur J Obstet Gynecol Reprod Biol 2017 Nov 14;218:27-32. Epub 2017 Sep 14.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejogrb.2017.09.013DOI Listing
November 2017

Genome-wide interaction study of dust mite allergen on lung function in children with asthma.

J Allergy Clin Immunol 2017 Oct 4;140(4):996-1003.e7. Epub 2017 Feb 4.

Division of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pa; University of Pittsburgh School of Medicine, Pittsburgh, Pa. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.12.967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544591PMC
October 2017

Circulating microRNAs and association with methacholine PC20 in the Childhood Asthma Management Program (CAMP) cohort.

PLoS One 2017 27;12(7):e0180329. Epub 2017 Jul 27.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180329PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531511PMC
October 2017

Vitamin D prenatal programming of childhood metabolomics profiles at age 3 y.

Am J Clin Nutr 2017 Oct 23;106(4):1092-1099. Epub 2017 Aug 23.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; and

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http://dx.doi.org/10.3945/ajcn.117.158220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611786PMC
October 2017

Association of intracranial aneurysm rupture with smoking duration, intensity, and cessation.

Neurology 2017 Sep 30;89(13):1408-1415. Epub 2017 Aug 30.

From the Department of Neurosurgery (A.C., Y.H.O., S.D., R. Du), Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Neurosurgery (A.C., R. Dammers), Erasmus Medical Center, Erasmus MC Stroke Center, Rotterdam, the Netherlands; Research Information Systems and Computing (V.M.C., V.G., S.M.), Partners Healthcare, Boston, MA; Center for Statistical Science (S.Y.), Tsinghua University, Beijing, China; Department of Medicine (S.Y., S.T.W.), Division of Rheumatology, Immunology and Allergy (N.A.S.), and Channing Division of Network Medicine (S.T.W., R. Du), Brigham and Women's Hospital, Boston, MA; Department of Computer Science (D.D.), Loyola University, Chicago, IL; Informatics Program (D.D., S.F., G.S.), Boston Children's Hospital; Department of Neurology (S.M.), Massachusetts General Hospital; and Biostatistics (T.C.), Harvard School of Public Health, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000004419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649762PMC
September 2017

The Association of Maternal Asthma and Early Pregnancy Vitamin D with Risk of Preeclampsia: An Observation From Vitamin D Antenatal Asthma Reduction Trial (VDAART).

J Allergy Clin Immunol Pract 2018 Mar - Apr;6(2):600-608.e2. Epub 2017 Sep 8.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass; Partners Center for Personalized Medicine, Partners Health Care, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2017.07.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843492PMC
September 2017

Asthma remission: Predicting future airways responsiveness using an miRNA network.

J Allergy Clin Immunol 2017 08 24;140(2):598-600.e8. Epub 2017 Feb 24.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2017.01.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546990PMC
August 2017

Detecting disease-associated genomic outcomes using constrained mixture of Bayesian hierarchical models for paired data.

PLoS One 2017 30;12(3):e0174602. Epub 2017 Mar 30.

Channing Division of Network Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174602PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373614PMC
August 2017

A high-throughput chemical screen identifies novel inhibitors and enhancers of anti-inflammatory functions of the glucocorticoid receptor.

Sci Rep 2017 08 7;7(1):7405. Epub 2017 Aug 7.

Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health, and Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/s41598-017-07565-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547123PMC
August 2017

Role of TGF-β in anti-rhinovirus immune responses in asthmatic patients.

J Allergy Clin Immunol 2017 07 27;140(1):283-286.e10. Epub 2017 Jan 27.

Department of Molecular Pneumology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.10.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754331PMC
July 2017

Applications of Metabolomics in the Study and Management of Preeclampsia; A Review of the Literature.

Metabolomics 2017 07 12;13(7). Epub 2017 Jun 12.

Channing Division of Network Medicine, Brigham and Women's Hospital Harvard Medical School, Boston MA 02115, USA.

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http://dx.doi.org/10.1007/s11306-017-1225-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247796PMC
July 2017

The Role of Vitamin D in the Transcriptional Program of Human Pregnancy.

PLoS One 2016 6;11(10):e0163832. Epub 2016 Oct 6.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0163832PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053446PMC
June 2017

Metabolomic profiling of lung function in Costa-Rican children with asthma.

Biochim Biophys Acta Mol Basis Dis 2017 06 7;1863(6):1590-1595. Epub 2017 Feb 7.

Channing Division of Network Medicine, Brigham and Women's Hospital Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bbadis.2017.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474172PMC
June 2017

Vitamin D in Host Defense: Implications for Future Research.

Am J Respir Cell Mol Biol 2017 06;56(6):692-693

1 Channing Division of Network Medicine Brigham and Women's Hospital Harvard Medical School Boston, Massachusetts.

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http://dx.doi.org/10.1165/rcmb.2017-0064EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516296PMC
June 2017

On the association analysis of genome-sequencing data: A spatial clustering approach for partitioning the entire genome into nonoverlapping windows.

Genet Epidemiol 2017 05 20;41(4):332-340. Epub 2017 Mar 20.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1002/gepi.22040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525021PMC
May 2017

Obesity and Airway Dysanapsis in Children with and without Asthma.

Am J Respir Crit Care Med 2017 Feb;195(3):314-323

1 Division of Pulmonary Medicine, Allergy, and Immunology, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1164/rccm.201605-1039OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328183PMC
February 2017

Vitamin D status through the first 10 years of life: A vital piece of the puzzle in asthma inception.

J Allergy Clin Immunol 2017 02 16;139(2):459-461. Epub 2016 Dec 16.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2016.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126376PMC
February 2017

Large-scale identification of patients with cerebral aneurysms using natural language processing.

Neurology 2017 Jan 7;88(2):164-168. Epub 2016 Dec 7.

From Research Information Systems and Computing (V.M.C., V.G., S.M.), Partners Healthcare; Boston Children's Hospital Informatics Program (D.D., S.F., G.S.); Harvard Medical School (D.D., S.Y., A.C., M.A.-E.-B., N.A.S., S.M., S.T.W., R.D.); Department of Medicine (S.Y., S.T.W.), Department of Neurosurgery (A.C., M.A.-E.-B., R.D.), Division of Rheumatology, Immunology and Allergy (N.A.S.), and Channing Division of Network Medicine (S.T.W., R.D.), Brigham and Women's Hospital, Boston, MA; Center for Statistical Science (S.Y.), Tsinghua University, Beijing, China; Department of Neurology (S.M.), Massachusetts General Hospital; and Biostatistics (T.C.), Harvard School of Public Health, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000003490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224711PMC
January 2017

Whole genome prediction and heritability of childhood asthma phenotypes.

Immun Inflamm Dis 2016 12 28;4(4):487-496. Epub 2016 Nov 28.

Channing Division of Network Medicine Brigham and Women's Hospital and Harvard Medical School Boston Massachusetts.

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http://dx.doi.org/10.1002/iid3.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134727PMC
December 2016

Genetic and Epigenetic Components of Aspirin-Exacerbated Respiratory Disease.

Immunol Allergy Clin North Am 2016 11;36(4):765-789

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.iac.2016.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720138PMC
November 2016

Can we prevent childhood asthma before birth? Summary of the VDAART results so far.

Expert Rev Respir Med 2016 10 6;10(10):1039-40. Epub 2016 Sep 6.

a Channing Division of Network Medicine , Brigham and Women's Hospital , Boston , MA , USA.

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http://dx.doi.org/10.1080/17476348.2016.1227257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131572PMC
October 2016

Biological Network Modeling and Systems Biology to Advance Our Understanding of Lung Disease.

Authors:
Scott T Weiss

Am J Respir Crit Care Med 2016 10;194(8):920-921

1 Harvard Medical School Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201604-0793EDDOI Listing
October 2016

CRISPLD2 (LGL1) inhibits proinflammatory mediators in human fetal, adult, and COPD lung fibroblasts and epithelial cells.

Physiol Rep 2016 09;4(17)

Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada Departments of Human Genetics and Pediatrics, McGill University, Montreal, Quebec, Canada

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http://dx.doi.org/10.14814/phy2.12942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027350PMC
September 2016

Implementing Personalized Medicine in the Academic Health Center.

Authors:
Scott T Weiss

J Pers Med 2016 Sep 21;6(3). Epub 2016 Sep 21.

Partners Center for Personalized Medicine, Partners Health Care, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040964PMC
http://dx.doi.org/10.3390/jpm6030018DOI Listing
September 2016

Decline in Lung Function in Childhood Asthma.

N Engl J Med 2016 08;375(7):e13

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http://dx.doi.org/10.1056/NEJMc1608228DOI Listing
August 2016

Prenatal Vitamin D and Offspring Wheezing--Reply.

JAMA 2016 Jun;315(24):2731

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2016.4121DOI Listing
June 2016