Scott N Gettinger

Scott N Gettinger

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Scott N Gettinger

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Comparison of Survival Rates After a Combination of Local Treatment and Systemic Therapy vs Systemic Therapy Alone for Treatment of Stage IV Non-Small Cell Lung Cancer.

JAMA Netw Open 2019 Aug 2;2(8):e199702. Epub 2019 Aug 2.

Section of Interventional Radiology, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.9702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707019PMC
August 2019

Immune Checkpoint Inhibitor-Associated Pericarditis.

J Thorac Oncol 2019 Jun 7;14(6):1102-1108. Epub 2019 Mar 7.

Section of Medical Oncology, Yale School of Medicine, New Haven, Connecticut; Department of Pathology, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1016/j.jtho.2019.02.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617516PMC
June 2019

Oncolytic virus immunotherapy: future prospects for oncology.

J Immunother Cancer 2018 12 4;6(1):140. Epub 2018 Dec 4.

Division of Interventional Radiology, Department of Radiology and Biomedical Imaging, Yale School of Medicine, 330 Cedar Street, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1186/s40425-018-0458-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280382PMC
December 2018

Cryotherapy for nodal metastasis in NSCLC with acquired resistance to immunotherapy.

J Immunother Cancer 2018 12 12;6(1):147. Epub 2018 Dec 12.

Division of Interventional Radiology, Department of Radiology and Biomedical Imaging, Yale School of Medicine, 330 Cedar Street, New Haven, CT, 06510, USA.

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http://dx.doi.org/10.1186/s40425-018-0468-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292083PMC
December 2018

Brigatinib versus Crizotinib in ALK-Positive Non-Small-Cell Lung Cancer.

N Engl J Med 2018 11 25;379(21):2027-2039. Epub 2018 Sep 25.

From the University of Colorado Cancer Center, Aurora (D.R.C.); Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine (H.R.K.), Samsung Medical Center (M.-J.A.), and Seoul National University Hospital (D.-W.K.), Seoul, National Cancer Center, Goyang (J.-Y.H.), Seoul National University Bundang Hospital, Seongnam (J.-S.L.), and Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju (K.H.L.) - all in South Korea; National Taiwan University Hospital (J.C.-H.Y.) and the Faculty of Medicine, School of Medicine, National Yang-Ming University (G.-C.C.), Taipei, and the Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung (G.-C.C.) - all in Taiwan; the Ludwig Boltzmann Institute for COPD and Respiratory Epidemiology, Department of Respiratory and Critical Care Medicine, Otto Wagner Hospital, Vienna (M.J.H.); Queen Elizabeth Hospital, Kowloon, Hong Kong (J.Y.-C.L.); Azienda Ospedaliera S. Giuseppe Moscati, Avellino (C.G.), the Scientific Institute of Romagna for the Study and Treatment of Cancer, Meldola (A.D.), Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS Struttura Operativa Complessa Oncologia Medica A, Aviano (A.B.), Thoracic Medical Oncology, Istituto Nazionale Tumori, IRCCS Fondazione G. Pascale, Naples (A.M.), and the Medical Oncology Unit, University Hospital of Parma, Parma (M.T.) - all in Italy; Complejo Hospitalario Universitario de A Coruña, Coruña (R.G.C.), and Vall d'Hebron University Hospital, Barcelona (E.F.) - both in Spain; the Department of Hematology and Oncology, University Department of Internal Medicine-Oncology, Pius-Hospital Medical Campus, University of Oldenburg, Oldenburg, Germany (F.G.); the Department of Medical Oncology, Christie NHS Foundation Trust, and Division of Cancer Sciences, University of Manchester, Manchester (R.C.), and Guy's and St. Thomas' NHS Foundation Trust (S.G.) and Royal Marsden Hospital and the National Heart and Lung Institute, Imperial College London (S.P.), London - all in the United Kingdom; Virginia Cancer Specialists Research Institute and US Oncology Research, The Woodlands, TX (A.S.); Yale Cancer Center, New Haven, CT (S.N.G.); and Millennium Pharmaceuticals, Cambridge, MA (N.G., J.H., D.K.).

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http://dx.doi.org/10.1056/NEJMoa1810171DOI Listing
November 2018

Exploratory Analysis of Brigatinib Activity in Patients With Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer and Brain Metastases in Two Clinical Trials.

J Clin Oncol 2018 09 16;36(26):2693-2701. Epub 2018 May 16.

D. Ross Camidge, University of Colorado Cancer Center, Aurora, CO; Dong-Wan Kim, Seoul National University Hospital; Myung-Ju Ahn, Samsung Medical Center; Dae Ho Lee, Asan Medical Center, Seoul, South Korea; Marcello Tiseo, University Hospital of Parma, Parma, Italy; Corey J. Langer, University of Pennsylvania, Philadelphia, PA; Alice T. Shaw, Massachusetts General Hospital, Boston; William Reichmann, Jeff Haney, Tim Clackson, and David Kerstein, ARIAD Pharmaceuticals, Cambridge, MA; Rudolf M. Huber, University Hospital of Munich, Munich, Germany; Maximilian J. Hochmair, Otto Wagner Hospital, Vienna, Austria; Lyudmila A. Bazhenova and Kathryn A. Gold, University of California San Diego Moores Cancer Center, La Jolla; Sai-Hong Ignatius Ou, University of California Irvine School of Medicine, Irvine, CA; Howard L. West, Swedish Cancer Institute, Seattle, WA; and Scott N. Gettinger, Yale Cancer Center, New Haven, CT.

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http://ascopubs.org/doi/10.1200/JCO.2017.77.5841
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http://dx.doi.org/10.1200/JCO.2017.77.5841DOI Listing
September 2018

Pityriasis rubra pilaris-like erythroderma in the setting of pembrolizumab therapy responsive to acitretin.

JAAD Case Rep 2018 Aug 9;4(7):669-671. Epub 2018 Aug 9.

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1016/j.jdcr.2018.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091308PMC
August 2018

Immuno-thermal ablations - boosting the anticancer immune response.

J Immunother Cancer 2017 10 17;5(1):78. Epub 2017 Oct 17.

Division of Interventional Radiology, Department of Radiology and Biomedical Imaging, Yale School of Medicine, 330 Cedar Street, New Haven, CT, 06510, USA.

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http://jitc.biomedcentral.com/articles/10.1186/s40425-017-02
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http://dx.doi.org/10.1186/s40425-017-0284-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644150PMC
October 2017

Brigatinib in Patients With Crizotinib-Refractory Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer: A Randomized, Multicenter Phase II Trial.

J Clin Oncol 2017 Aug 5;35(22):2490-2498. Epub 2017 May 5.

Dong-Wan Kim, Seoul National University Hospital; Myung-Ju Ahn, Samsung Medical Center; Sang-We Kim, Asan Medical Center, Seoul, South Korea; Marcello Tiseo, University Hospital of Parma, Parma, Italy; Karen L. Reckamp, City of Hope, Duarte, CA; Karin Holmskov Hansen, Odense University Hospital, Odense, Denmark; Rudolf M. Huber, University Hospital of Munich, German Centre for Lung Research, Munich, Germany; Howard L. West, Swedish Cancer Institute, Seattle, WA; Harry J.M. Groen, University of Groningen, University Medical Center Groningen, Groningen; Egbert F. Smit, VU University Medical Center, Amsterdam, the Netherlands; Maximilian J. Hochmair, Otto Wagner Hospital, Vienna, Austria; Natasha B. Leighl, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Scott N. Gettinger, Yale Cancer Center, New Haven, CT; Corey J. Langer, University of Pennsylvania Abramson Cancer Center, Philadelphia, PA; Luis G. Paz-Ares Rodríguez, Hospital Universitario 12 de Octubre, Madrid, Spain; Edward S. Kim, Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC; William Reichmann, Frank G. Haluska, and David Kerstein, ARIAD Pharmaceuticals, Cambridge, MA; and D. Ross Camidge, University of Colorado Cancer Center, Aurora, CO.

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http://dx.doi.org/10.1200/JCO.2016.71.5904DOI Listing
August 2017

Management of Brain Metastases in Tyrosine Kinase Inhibitor-Naïve Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer: A Retrospective Multi-Institutional Analysis.

J Clin Oncol 2017 Apr 23;35(10):1070-1077. Epub 2017 Jan 23.

William J. Magnuson, Nataniel H. Lester-Coll, Scott N. Gettinger, Joseph N. Contessa, James B. Yu, and Veronica L. Chiang, Yale School of Medicine, New Haven, CT; Abraham J. Wu, T. Jonathan Yang, Natalie A. Lockney, Naamit K. Gerber, and Kathryn Beal, Memorial Sloan Kettering Cancer Center, New York, NY; Arya Amini, Tejas Patil, Brian D. Kavanagh, and D. Ross Camidge, University of Colorado School of Medicine, Denver, CO; Steven E. Braunstein and Lauren C. Boreta, University of California-San Francisco, San Francisco, CA; Suresh K. Balasubramanian and Manmeet S. Ahluwalia, Cleveland Clinic Foundation, Cleveland, OH; and Niteshkumar G. Rana and Albert Attia, Vanderbilt University School of Medicine, Nashville, TN.

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http://dx.doi.org/10.1200/JCO.2016.69.7144DOI Listing
April 2017

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2016 Oct;34(30):3638-3647

Vassiliki Papadimitrakopoulou, J. Jack Lee, Ignacio I. Wistuba, Anne S. Tsao, Frank V. Fossella, Neda Kalhor, Sanjay Gupta, Lauren Averett Byers, Julie G. Izzo, Ximing Tang, Ferdinandos Skoulidis, Don L. Gibbons, Li Shen, Caimiao Wei, Lixia Diao, S. Andrew Peng, Jing Wang, Alda L. Tam, John V. Heymach, and Waun Ki Hong, The University of Texas MD Anderson Cancer Center, Houston, TX; Scott N. Gettinger, Sarah B. Goldberg, Ja Seok Koo, and Roy S. Herbst, Yale University, New Haven, CT; Vincent A. Miller, Foundation Medicine, Cambridge, MA; Kevin R. Coombes, Ohio State University College of Medicine, Columbus, OH; and David J. Mauro and Eric H. Rubin, Merck, North Wales, PA.

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http://dx.doi.org/10.1200/JCO.2015.66.0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065110PMC
October 2016

Impact of Deferring Radiation Therapy in Patients With Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer Who Develop Brain Metastases.

Int J Radiat Oncol Biol Phys 2016 06 2;95(2):673-9. Epub 2016 Feb 2.

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1016/j.ijrobp.2016.01.037DOI Listing
June 2016

Immune-related sarcoidosis observed in combination ipilimumab and nivolumab therapy.

JAAD Case Rep 2016 May 14;2(3):264-8. Epub 2016 Jul 14.

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1016/j.jdcr.2016.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949498PMC
May 2016

Preliminary Safety, Pharmacokinetics, and Efficacy of Regorafenib, Cisplatin, and Pemetrexed in Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancers.

Clin Lung Cancer 2015 Nov 20;16(6):514-22. Epub 2015 Apr 20.

Department of Medicine, Section of Medical Oncology, Yale University School of Medicine, Yale Cancer Center, New Haven, CT.

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http://dx.doi.org/10.1016/j.cllc.2015.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750397PMC
November 2015

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer.

N Engl J Med 2015 Oct 27;373(17):1627-39. Epub 2015 Sep 27.

From the Fox Chase Cancer Center, Philadelphia (H.B.); Hospital Universitario Virgen del Rocio, Seville (L.P.-A.), Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona (E.F.), and Hospital de Madrid, Norte Sanchinarro, Madrid (E.H.) - all in Spain; Vanderbilt-Ingram Cancer Center (L.H.), and Sarah Cannon Research Institute and Tennessee Oncology (D.R.S.) - both in Nashville; Thoraxklinik, Heidelberg University Hospital, Heidelberg (M.S.) and Robert-Bosch-Krankenhaus Stuttgart, Gerlingen (M.K.) - both in Germany; Duke University Medical Center, Durham, NC (N.E.R.); University of Washington, Seattle (L.Q.C.); University of Chicago Medicine and Biological Sciences, Chicago (E.E.V.); Aix Marseille University, Assistance Publique-Hôpitaux de Marseille, Marseille (F.B.), Centre Léon Bérard, Lyon (J.F.), and Centre Hospitalier Universitaire de Rennes, Rennes (H.L.) - all in France; Instituto Nacional de Cancerologia, Mexico City (O.A.); Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRCCS, Meldola, Forlì-Cesena (M.A.B.), and Ospedale di Perugia, Perugia (L.C.) - both in Italy; N.N. Blokhin Russian Cancer Research Center, Moscow (E.P.); University of Texas Southwestern Medical Center, Dallas (D.E.G.); Yale Comprehensive Cancer Center, New Haven, CT (S.N.G.); Memorial Sloan Kettering Cancer Center, New York (C.M.R., N.R.); University of Texas M.D. Anderson Cancer Center, Houston (G.R.B.); H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (S.J.A.); Bristol-Myers Squibb, Princeton, NJ (C.D., C.T.H., F.G.F.); and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore (J.R.B.).

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http://dx.doi.org/10.1056/NEJMoa1507643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705936PMC
October 2015

Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2015 Jun 20;33(18):2004-12. Epub 2015 Apr 20.

Scott N. Gettinger and Mario Sznol, Yale Cancer Center, New Haven, CT; Leora Horn, David P. Carbone, and Jeffrey A. Sosman, Vanderbilt University Medical Center; David R. Spigel, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Leena Gandhi, David M. Jackman, and F. Stephen Hodi, Dana-Farber Cancer Institute; Rebecca S. Heist and Lecia V. Sequist, Massachusetts General Hospital Cancer Center; David F. McDermott, Beth Israel Deaconess Medical Center, Boston, MA; Scott J. Antonia and Mary C. Pinder-Schenck, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; Naiyer A. Rizvi, Richard D. Carvajal, and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center, New York, NY; John D. Powderly, Carolina BioOncology Institute, Huntersville, NC; David C. Smith, University of Michigan, Ann Arbor, MI; Philip Leming, Christ Hospital Cancer Center, Cincinnati, OH; Suzanne L. Topalian, Drew M. Pardoll, and Julie R. Brahmer, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD; and Vindira Sankar, Christoph M. Ahlers, Mark Salvati, Jon M. Wigginton, Georgia D. Kollia, and Ashok K. Gupta, Bristol-Myers Squibb, Princeton, NJ.

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http://jco.ascopubs.org/content/early/2015/04/15/JCO.2014.58
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.3708
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http://dx.doi.org/10.1200/JCO.2014.58.3708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672027PMC
June 2015

Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo.

J Immunol 2015 Feb 24;194(3):950-9. Epub 2014 Dec 24.

Department of Medicine, Yale University School of Medicine, New Haven, CT 06520; Smilow Cancer Center, Yale University School of Medicine, New Haven, CT 06520; Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520

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http://dx.doi.org/10.4049/jimmunol.1401686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380504PMC
February 2015

A clinical model for identifying radiosensitive tumor genotypes in non-small cell lung cancer.

Clin Cancer Res 2013 Oct 29;19(19):5523-32. Epub 2013 Jul 29.

Authors' Affiliations: Departments of Therapeutic Radiology, Medical Oncology, Neurosurgery, Yale University School of Medicine; and Yale Center for Analytic Sciences, Yale University School of Public Health, New Haven, Connecticut.

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http://clincancerres.aacrjournals.org/content/early/2013/07/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-0836DOI Listing
October 2013

Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma.

Cancer Cytopathol 2013 Sep 12;121(9):500-7. Epub 2013 Mar 12.

Department of Pathology, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1002/cncy.21288DOI Listing
September 2013

SOX2-specific adaptive immunity and response to immunotherapy in non-small cell lung cancer.

Oncoimmunology 2013 Jul 10;2(7):e25205. Epub 2013 Jun 10.

Department of Pediatrics; Yale University; New Haven, CT USA ; Yale Cancer Center; Yale University; New Haven, CT USA.

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http://www.tandfonline.com/doi/abs/10.4161/onci.25205
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http://dx.doi.org/10.4161/onci.25205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782159PMC
July 2013

Late recurrence of basaloid carcinoma initially treated as a small cell lung cancer.

J Thorac Dis 2013 Apr;5(2):E68-70

Section of Thoracic Surgery, Yale University School of Medicine and Yale-New Haven Hospital, New Haven, CT, USA.

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http://dx.doi.org/10.3978/j.issn.2072-1439.2013.03.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621916PMC
April 2013

Targeted therapy for thyroid cancer: An updated review of investigational agents.

Curr Opin Investig Drugs 2010 Jun;11(6):661-8

Yale Cancer Center, 333 Cedar Street, FMP 124, New Haven, CT 06520, USA.

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June 2010

Management of patients with advanced non-small cell lung cancer: current and emerging options.

Drugs 2010 ;70(2):167-79

Yale Cancer Center/Yale University School of Medicine, New Haven, Connecticut, USA.

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http://link.springer.com/10.2165/11532200-000000000-00000
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http://dx.doi.org/10.2165/11532200-000000000-00000DOI Listing
April 2010

Novel chemotherapy options for advanced thyroid tumors: small molecules offer great hope.

Curr Opin Oncol 2008 Jan;20(1):19-24

Yale Cancer Center, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1097/CCO.0b013e3282f28373DOI Listing
January 2008