Scott Landfear

Scott Landfear

UNVERIFIED PROFILE

Are you Scott Landfear?   Register this Author

Register author
Scott Landfear

Scott Landfear

Publications by authors named "Scott Landfear"

Are you Scott Landfear?   Register this Author

54Publications

668Reads

14Profile Views

Vaccinia Virus Vectors Targeting Peptides for MHC Class II Presentation to CD4 T Cells.

Immunohorizons 2020 01 2;4(1):1-13. Epub 2020 Jan 2.

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/immunohorizons.1900070DOI Listing
January 2020

Sensing What's Out There - Kinetoplastid Parasites.

Trends Parasitol 2019 04 14;35(4):274-277. Epub 2019 Jan 14.

Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pt.2018.12.004DOI Listing
April 2019

Protean permeases: Diverse roles for membrane transport proteins in kinetoplastid protozoa.

Authors:
Scott M Landfear

Mol Biochem Parasitol 2019 01 24;227:39-46. Epub 2018 Dec 24.

Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, OR, 97239, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molbiopara.2018.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415942PMC
January 2019

Glucose Transporters and Virulence in .

mSphere 2018 08 1;3(4). Epub 2018 Aug 1.

Department of Molecular Microbiology and Immunology, Oregon Health and Sciences University, Portland, Oregon, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/mSphere.00349-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070740PMC
August 2018

Leishmania mexicana can utilize amino acids as major carbon sources in macrophages but not in animal models.

Mol Microbiol 2018 04 2;108(2):143-158. Epub 2018 Mar 2.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 30 Flemington Road, Parkville, Victoria 3010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/mmi.13923DOI Listing
April 2018

Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening.

PLoS Negl Trop Dis 2017 12 29;11(12):e0006157. Epub 2017 Dec 29.

Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0006157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764437PMC
December 2017

KHARON Is an Essential Cytoskeletal Protein Involved in the Trafficking of Flagellar Membrane Proteins and Cell Division in African Trypanosomes.

J Biol Chem 2016 09 3;291(38):19760-73. Epub 2016 Aug 3.

From the Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon 97239 and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M116.739235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025667PMC
September 2016

Targeting the Cytochrome bc1 Complex of Leishmania Parasites for Discovery of Novel Drugs.

Antimicrob Agents Chemother 2016 08 22;60(8):4972-82. Epub 2016 Jul 22.

Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.00850-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958202PMC
August 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Kharon1 null mutants of Leishmania mexicana are avirulent in mice and exhibit a cytokinesis defect within macrophages.

PLoS One 2015 12;10(8):e0134432. Epub 2015 Aug 12.

Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134432PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534133PMC
May 2016

Flagellar membrane proteins in kinetoplastid parasites.

IUBMB Life 2015 Sep 25;67(9):668-76. Epub 2015 Aug 25.

Department of Molecular Microbiology and Immunology, Oregon Health and Sciences University, Portland, OR, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/iub.1411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662044PMC
September 2015

Coxiella burnetii and Leishmania mexicana residing within similar parasitophorous vacuoles elicit disparate host responses.

Front Microbiol 2015 7;6:794. Epub 2015 Aug 7.

Department of Biology and Center for Life in Extreme Environments, Portland State University, Portland, OR USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2015.00794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528172PMC
August 2015

Transporters, channels and receptors in flagella.

Channels (Austin) 2014 ;8(6):477-8

a Department of Molecular Microbiology & Immunology ; Oregon Health Sciences University ; Portland , OR USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/19336950.2014.985481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594579PMC
May 2015

Identification of the intracellular gate for a member of the equilibrative nucleoside transporter (ENT) family.

J Biol Chem 2014 Mar 4;289(13):8799-809. Epub 2014 Feb 4.

From the Departments of Molecular Microbiology and Immunology and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M113.546960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979384PMC
March 2014

'Transient' genetic suppression facilitates generation of hexose transporter null mutants in Leishmania mexicana.

Mol Microbiol 2013 Jan 10;87(2):412-29. Epub 2012 Dec 10.

Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/mmi.12106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545093PMC
January 2013

Cysteine cross-linking defines the extracellular gate for the Leishmania donovani nucleoside transporter 1.1 (LdNT1.1).

J Biol Chem 2012 Dec 13;287(53):44036-45. Epub 2012 Nov 13.

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M112.414433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531720PMC
December 2012

Both sequence and context are important for flagellar targeting of a glucose transporter.

J Cell Sci 2012 Jul 30;125(Pt 14):3293-8. Epub 2012 Mar 30.

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.103028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516375PMC
July 2012

Lysosomal degradation of Leishmania hexose and inositol transporters is regulated in a stage-, nutrient- and ubiquitin-dependent manner.

Int J Parasitol 2011 Jun 9;41(7):791-800. Epub 2011 Apr 9.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Flemington Rd, Parkville, Victoria 3010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2011.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592973PMC
June 2011

Nutrient transport and pathogenesis in selected parasitic protozoa.

Authors:
Scott M Landfear

Eukaryot Cell 2011 Apr 7;10(4):483-93. Epub 2011 Jan 7.

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/EC.00287-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127635PMC
April 2011

Remodeling of protein and mRNA expression in Leishmania mexicana induced by deletion of glucose transporter genes.

Mol Biochem Parasitol 2011 Jan 24;175(1):39-48. Epub 2010 Sep 24.

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molbiopara.2010.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974008PMC
January 2011

Purine restriction induces pronounced translational upregulation of the NT1 adenosine/pyrimidine nucleoside transporter in Leishmania major.

Mol Microbiol 2010 Oct 2;78(1):108-18. Epub 2010 Aug 2.

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2958.2010.07328.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971681PMC
October 2010

Adaptive responses to purine starvation in Leishmania donovani.

Mol Microbiol 2010 Oct;78(1):92-107

Department of Biochemistry and Molecular Biology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239-3098, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2958.2010.07327.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964060PMC
October 2010

Glucose transporters in parasitic protozoa.

Authors:
Scott M Landfear

Methods Mol Biol 2010 ;637:245-62

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-60761-700-6_13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058963PMC
July 2010

Arsenic transport by zebrafish aquaglyceroporins.

BMC Mol Biol 2009 Nov 25;10:104. Epub 2009 Nov 25.

Dept. of Biological Sciences, Oakland University, Rochester, MI 48309, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2199-10-104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788550PMC
November 2009

Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis.

Proc Natl Acad Sci U S A 2009 Aug 17;106(31):12998-3003. Epub 2009 Jul 17.

Department of Molecular Parasitology, Humboldt University, Philippstrasse 13, 10115, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0903831106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722337PMC
August 2009

An ab Initio structural model of a nucleoside permease predicts functionally important residues.

J Biol Chem 2009 Jul 8;284(28):19067-76. Epub 2009 May 8.

Departments of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.017947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707223PMC
July 2009

An acid-activated nucleobase transporter from Leishmania major.

J Biol Chem 2009 Jun 14;284(24):16164-9. Epub 2009 Apr 14.

Department of Molecular Microbiology and Immunology, Neuroscience Institute, Oregon Health & Science University, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.006718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713545PMC
June 2009

Two novel nucleobase/pentamidine transporters from Trypanosoma brucei.

Mol Biochem Parasitol 2009 Feb 17;163(2):67-76. Epub 2008 Oct 17.

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molbiopara.2008.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630410PMC
February 2009

An expression system to screen for inhibitors of parasite glucose transporters.

Mol Biochem Parasitol 2008 Nov 30;162(1):71-6. Epub 2008 Jul 30.

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molbiopara.2008.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771778PMC
November 2008

Drugs and transporters in kinetoplastid protozoa.

Authors:
Scott M Landfear

Adv Exp Med Biol 2008 ;625:22-32

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-0-387-77570-8_3DOI Listing
April 2008

Molecular genetic analysis of purine nucleobase transport in Leishmania major.

Mol Microbiol 2007 Jun;64(5):1228-43

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2958.2007.05730.xDOI Listing
June 2007

Phenotypic characterization of a glucose transporter null mutant in Leishmania mexicana.

Mol Biochem Parasitol 2007 May 18;153(1):9-18. Epub 2007 Jan 18.

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molbiopara.2007.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2062483PMC
May 2007

Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid.

Biochem Biophys Res Commun 2006 Dec 17;351(2):424-30. Epub 2006 Oct 17.

Department of Biochemistry and Molecular Biology, Wayne State University, School of Medicine, Detroit, MI 48201, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2006.10.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764621PMC
December 2006

Comprehensive examination of charged intramembrane residues in a nucleoside transporter.

J Biol Chem 2006 Aug 12;281(32):22647-55. Epub 2006 Jun 12.

Department of Molecular Microbiology and Immunology and Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M602366200DOI Listing
August 2006

Metabolic changes in glucose transporter-deficient Leishmania mexicana and parasite virulence.

J Biol Chem 2006 Jul 17;281(29):20068-76. Epub 2006 May 17.

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M603265200DOI Listing
July 2006

Cell biology: when the tail wags the dog.

Authors:
Scott M Landfear

Nature 2006 Mar;440(7081):153-4

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/440153aDOI Listing
March 2006

The genome of the African trypanosome Trypanosoma brucei.

Authors:
Matthew Berriman Elodie Ghedin Christiane Hertz-Fowler Gaëlle Blandin Hubert Renauld Daniella C Bartholomeu Nicola J Lennard Elisabet Caler Nancy E Hamlin Brian Haas Ulrike Böhme Linda Hannick Martin A Aslett Joshua Shallom Lucio Marcello Lihua Hou Bill Wickstead U Cecilia M Alsmark Claire Arrowsmith Rebecca J Atkin Andrew J Barron Frederic Bringaud Karen Brooks Mark Carrington Inna Cherevach Tracey-Jane Chillingworth Carol Churcher Louise N Clark Craig H Corton Ann Cronin Rob M Davies Jonathon Doggett Appolinaire Djikeng Tamara Feldblyum Mark C Field Audrey Fraser Ian Goodhead Zahra Hance David Harper Barbara R Harris Heidi Hauser Jessica Hostetler Al Ivens Kay Jagels David Johnson Justin Johnson Kristine Jones Arnaud X Kerhornou Hean Koo Natasha Larke Scott Landfear Christopher Larkin Vanessa Leech Alexandra Line Angela Lord Annette Macleod Paul J Mooney Sharon Moule David M A Martin Gareth W Morgan Karen Mungall Halina Norbertczak Doug Ormond Grace Pai Chris S Peacock Jeremy Peterson Michael A Quail Ester Rabbinowitsch Marie-Adele Rajandream Chris Reitter Steven L Salzberg Mandy Sanders Seth Schobel Sarah Sharp Mark Simmonds Anjana J Simpson Luke Tallon C Michael R Turner Andrew Tait Adrian R Tivey Susan Van Aken Danielle Walker David Wanless Shiliang Wang Brian White Owen White Sally Whitehead John Woodward Jennifer Wortman Mark D Adams T Martin Embley Keith Gull Elisabetta Ullu J David Barry Alan H Fairlamb Fred Opperdoes Barclay G Barrell John E Donelson Neil Hall Claire M Fraser Sara E Melville Najib M El-Sayed

Science 2005 Jul;309(5733):416-22

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1112642DOI Listing
July 2005

Functional expression and characterization of a purine nucleobase transporter gene from Leishmania major.

Mol Membr Biol 2004 Jan-Feb;21(1):11-8

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97201, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/0968768031000140845DOI Listing
August 2004

A novel purine nucleoside transporter whose expression is up-regulated in the short stumpy form of the Trypanosoma brucei life cycle.

Mol Biochem Parasitol 2004 Aug;136(2):265-72

Department of Molecular Microbiology & Immunology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, L220, Portland, OR 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molbiopara.2004.04.009DOI Listing
August 2004

Transmembrane domain 5 of the LdNT1.1 nucleoside transporter is an amphipathic helix that forms part of the nucleoside translocation pathway.

Biochemistry 2004 Jun;43(21):6793-802

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon 97239, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi049873mDOI Listing
June 2004

Sequences required for the flagellar targeting of an integral membrane protein.

Mol Biochem Parasitol 2004 May;135(1):89-100

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239-3098, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molbiopara.2004.01.009DOI Listing
May 2004

Nucleoside and nucleobase transporters in parasitic protozoa.

Eukaryot Cell 2004 Apr;3(2):245-54

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon 97239-3098, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC387651PMC
http://dx.doi.org/10.1128/ec.3.2.245-254.2004DOI Listing
April 2004

The adenosine analog tubercidin inhibits glycolysis in Trypanosoma brucei as revealed by an RNA interference library.

J Biol Chem 2003 Nov 12;278(47):46596-600. Epub 2003 Sep 12.

Department of Biological Chemistry, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M309320200DOI Listing
November 2003

Equilibrative nucleoside transporter family members from Leishmania donovani are electrogenic proton symporters.

J Biol Chem 2003 Sep 30;278(37):35127-34. Epub 2003 Jun 30.

Vollum Institute, Oregon Health & Science University, Portland, Oregon 97239-3098, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M306188200DOI Listing
September 2003

Molecular and functional characterization of the first nucleobase transporter gene from African trypanosomes.

Mol Biochem Parasitol 2003 Aug;130(2):101-10

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97201, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0166-6851(03)00167-1DOI Listing
August 2003

Genetic characterization of glucose transporter function in Leishmania mexicana.

Proc Natl Acad Sci U S A 2003 Apr 21;100(7):3901-6. Epub 2003 Mar 21.

Institute of Biomedical and Life Sciences, Division of Infection and Immunity, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0630165100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153020PMC
April 2003

Trypanosomatid transcription factors: waiting for Godot.

Authors:
Scott M Landfear

Proc Natl Acad Sci U S A 2003 Jan 30;100(1):7-9. Epub 2002 Dec 30.

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland 97201, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0337508100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140865PMC
January 2003

Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions.

J Biol Chem 2002 Jun 5;277(24):21499-504. Epub 2002 Apr 5.

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon 97201, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M202319200DOI Listing
June 2002