Publications by authors named "Scott L Letendre"

100Publications

Nucleic acid oxidation is associated with biomarkers of neurodegeneration in CSF in people with HIV.

Neurol Neuroimmunol Neuroinflamm 2020 11 14;7(6). Epub 2020 Oct 14.

From the Departments of Neurosciences and Psychiatry, University of California (R.J.E.), San Diego; Department of Psychiatry, University of California (D.J.M., E.E.S., R.K.H.), San Diego; Department of Medicine, University of California (S.M., T.H.), San Diego; Vanderbilt University (D.S., J.A.F.), Nashville, Tennessee; and Departments of Medicine and Psychiatry, University of California (S.L.L.), San Diego.

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http://dx.doi.org/10.1212/NXI.0000000000000902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577534PMC
November 2020

Efficacy and safety of two-drug regimens for treatment of HIV in the central nervous system.

AIDS 2020 11;34(13):1975-1977

University of California, San Diego, San Diego, California, USA.

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http://dx.doi.org/10.1097/QAD.0000000000002665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536841PMC
November 2020

Lower CSF homovanillic acid relates to higher burden of neuroinflammation and depression in people with HIV disease.

Brain Behav Immun 2020 Nov 20;90:353-363. Epub 2020 Sep 20.

Department of Psychiatry, University of California, San Diego, HIV Neurobehavioral Research Program, San Diego, CA, USA; Department of Neurosciences, University of California, San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1016/j.bbi.2020.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544671PMC
November 2020

Methamphetamine and Cannabis: A Tale of Two Drugs and their Effects on HIV, Brain, and Behavior.

J Neuroimmune Pharmacol 2020 Sep 15. Epub 2020 Sep 15.

Department of Psychiatry, HIV Neurobehavioral Research Program, University of California, San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1007/s11481-020-09957-0DOI Listing
September 2020

Glucan rich nutrition does not increase gut translocation of beta-glucan.

Mycoses 2020 Aug 11. Epub 2020 Aug 11.

Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1111/myc.13161DOI Listing
August 2020

COMT val158met genotype alters the effects of methamphetamine dependence on dopamine and dopamine-related executive function: preliminary findings.

Psychiatry Res 2020 10 2;292:113269. Epub 2020 Jul 2.

Department of Psychiatry, University of California, San Diego, HIV Neurobehavioral Research Program, San Diego, CA, USA; Department of Neurosciences, University of California, San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1016/j.psychres.2020.113269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530039PMC
October 2020

Predictors of worsening neuropathy and neuropathic pain after 12 years in people with HIV.

Ann Clin Transl Neurol 2020 07 3;7(7):1166-1173. Epub 2020 Jul 3.

Departments of Medicine and Psychiatry, University of California, San Diego, La Jolla, California.

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http://dx.doi.org/10.1002/acn3.51097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359117PMC
July 2020

Felt Age Discrepancy Differs by HIV Serostatus: A Secondary Analysis.

J Assoc Nurses AIDS Care 2020 Sep-Oct;31(5):587-597

Maulika Kohli, BA, is a Doctoral Researcher, San Diego State University/University of California San Diego, Joint Doctoral Program in Clinical Psychology, San Diego, California, USA. Lily Kamalyan, MA, is a Doctoral Researcher, San Diego State University/University of California San Diego, Joint Doctoral Program in Clinical Psychology, San Diego, California, USA. Elizabeth C. Pasipanodya, PhD, is a Postdoctoral Researcher, Santa Clara Valley Medical Center, Rehabilitation Research Center, San Jose, California, USA. Anya Umlauf, MS, is a Senior Statistician, Department of Psychiatry, University of California, San Diego, San Diego, California, USA. Raeanne C. Moore, PhD, is an Associate Professor, Department of Psychiatry, University of California, San Diego, San Diego, California, USA. Scott L. Letendre, MD, is a Professor of Medicine and Psychiatry, Department of Medicine, University of California San Diego, San Diego, California, USA. Dilip V. Jeste, MD, is a Director, Sam and Rose Stein Institute for Research on Aging, University of California San Diego, San Diego, California, USA. David J. Moore, PhD, is a Professor of Psychiatry, Department of Psychiatry, University of California, San Diego, San Diego, California, USA.

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http://dx.doi.org/10.1097/JNC.0000000000000184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540963PMC
July 2020

Cerebrospinal Fluid Norepinephrine and Neurocognition in HIV and Methamphetamine Dependence.

J Acquir Immune Defic Syndr 2020 Oct;85(2):e12-e22

Department of Psychiatry, University of California, San Diego, HIV Neurobehavioral Research Program, San Diego, CA.

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http://dx.doi.org/10.1097/QAI.0000000000002422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492443PMC
October 2020

Heme oxygenase-1 promoter (GT) polymorphism associates with HIV neurocognitive impairment.

Neurol Neuroimmunol Neuroinflamm 2020 05 10;7(3). Epub 2020 Apr 10.

From the Department of Neurology (R. Garza, A.J.G., B.L.B., Y.G.-M., A.L.G., D.L.K.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Department of Pathology (B.B.G.), University of Texas Medical Branch, Galveston; Department of Family Medicine & Public Health (B.T.), University of Botswana, Gaborone; Departments of Medicine and Biostatistics (R. Gross), Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia; and Department of Medicine (S.L.L.), University of California, San Diego.

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http://dx.doi.org/10.1212/NXI.0000000000000710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176253PMC
May 2020

Better executive function is independently associated with full HIV suppression during combination therapy.

AIDS 2019 12;33(15):2309-2316

aDepartment of Medicine, Emory University School of Medicine, Atlanta, Georgia bDepartment of Psychiatry, University of California at San Diego School of Medicine, La Jolla, California, USA cUniversity of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico dDepartment of Biostatistics and Bioinformatics, Emory University Rollins School of Public Health, Atlanta, Georgia eDepartment of Neurosciences fDepartment of Medicine, University of California at San Diego School of Medicine, San Diego, California, USA.

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http://dx.doi.org/10.1097/QAD.0000000000002348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905116PMC
December 2019

Correlates of HIV RNA concentrations in cerebrospinal fluid during antiretroviral therapy: a longitudinal cohort study.

Lancet HIV 2019 07 14;6(7):e456-e462. Epub 2019 Jun 14.

Department of Psychiatry, University of California San Diego, San Diego, CA, USA; Department of Medicine, University of California San Diego, San Diego, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/S2352-3018(19)30143-2DOI Listing
July 2019

CROI 2019: neurologic complications of HIV disease.

Top Antivir Med 2019 Apr;27(1):26-33

University of California San Diego, San Diego, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550359PMC
April 2019

Comparison of bead array and glass nanoreactor multi-analyte platforms for the evaluation of CNS and peripheral inflammatory markers during HIV infection.

J Immunol Methods 2019 02 20;465:7-12. Epub 2018 Nov 20.

Department of Medicine, University of California at San Diego School of Medicine, La Jolla, CA, United States; Department of Psychiatry, University of California at San Diego School of Medicine, La Jolla, CA, United States.

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http://dx.doi.org/10.1016/j.jim.2018.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456896PMC
February 2019

Neurocognitive functioning predicts frailty index in HIV.

Neurology 2018 07 6;91(2):e162-e170. Epub 2018 Jun 6.

From the University of California, San Diego, School of Medicine (H.O.); San Diego State University/University of California, San Diego Joint Doctoral Program in Clinical Psychology (E.W.P.); Departments of Psychiatry (R.C.M., D.V.J., I.G., D.J.M.), Neurosciences (R.J.E.), and Medicine (S.L.L.), University of California, San Diego; VA San Diego Healthcare System (R.C.M.), CA; and Sam and Rose Stein Institute for Research on Aging (D.V.J.), University of California, San Diego.

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http://dx.doi.org/10.1212/WNL.0000000000005761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053109PMC
July 2018

Development and validation of an LC-MS/MS assay for tenofovir and tenofovir alafenamide in human plasma and cerebrospinal fluid.

J Pharm Biomed Anal 2018 Jul 23;156:163-169. Epub 2018 Apr 23.

Translational Pharmacology Research Core, Center for Integrated Global Biomedical Sciences, New York State Center of Excellence in Bioinformatics and Life Sciences, Department of Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S07317085173278
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http://dx.doi.org/10.1016/j.jpba.2018.04.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984727PMC
July 2018

HIV, prospective memory, and cerebrospinal fluid concentrations of quinolinic acid and phosphorylated Tau.

J Neuroimmunol 2018 06 18;319:13-18. Epub 2018 Mar 18.

Department of Medicine, University of California at San Diego, La Jolla, CA, United States; Department of Psychiatry, University of California at San Diego, La Jolla, CA, United States.

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http://dx.doi.org/10.1016/j.jneuroim.2018.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918423PMC
June 2018

At-Risk Alcohol Use is Associated with Antiretroviral Treatment Nonadherence Among Adults Living with HIV/AIDS.

Alcohol Clin Exp Res 2017 Aug 5;41(8):1518-1525. Epub 2017 Jul 5.

HIV Neurobehavioral Research Program, Department of Psychiatry, University of California, San Diego, San Diego, California.

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http://dx.doi.org/10.1111/acer.13433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564671PMC
August 2017

Everyday functional ability in HIV and methamphetamine dependence.

Drug Alcohol Depend 2017 06 28;175:60-66. Epub 2017 Mar 28.

Department of Psychiatry, University of California San Diego, La Jolla, CA, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2017.01.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603270PMC
June 2017

Coagulation imbalance and neurocognitive functioning in older HIV-positive adults on suppressive antiretroviral therapy.

AIDS 2017 03;31(6):787-795

aSDSU/UCSD Joint Doctoral Program in Clinical Psychology bDepartment of Psychiatry cDepartment of Family Medicine and Public Health dDepartment of Neurosciences eDepartment of Medicine, University of California, San Diego, La Jolla, California fDepartment of Pharmacy Practice, University of Buffalo, Buffalo, New York, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466004PMC
March 2017

Higher Cystatin C Levels Are Associated With Neurocognitive Impairment in Older HIV+ Adults.

J Acquir Immune Defic Syndr 2017 Mar;74(3):243-249

*Department of School of Medicine, John A. Burns School of Medicine, University of Hawaii Honolulu, HI; Departments of †Psychiatry; ‡Neurosciences, University of California, San Diego, San Diego, CA; §Stein Institute for Research on Aging, University of California, San Diego, San Diego, CA; and ‖Department of Medicine, University of California, San Diego, San Diego, CA.

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http://dx.doi.org/10.1097/QAI.0000000000001235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303169PMC
March 2017

Elevated Markers of Vascular Remodeling and Arterial Stiffness Are Associated With Neurocognitive Function in Older HIV+ Adults on Suppressive Antiretroviral Therapy.

J Acquir Immune Defic Syndr 2017 Feb;74(2):134-141

*Joint Doctoral Program in Clinical Psychology, SDSU/UCSD, San Diego, CA; Departments of †Psychiatry; ‡Family Medicine and Public Health; §Neurosciences; and ‖Medicine, University of California, San Diego, La Jolla, CA.

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http://dx.doi.org/10.1097/QAI.0000000000001230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233588PMC
February 2017

Tryptophan Metabolism and Its Relationship with Depression and Cognitive Impairment Among HIV-infected Individuals.

Int J Tryptophan Res 2016 26;9:79-88. Epub 2016 Oct 26.

University of California, San Diego, Departments of Neurosciences and Psychiatry, San Diego, CA, USA.

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http://dx.doi.org/10.4137/IJTR.S36464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083113PMC
October 2016

HIV-associated neurocognitive disorder is associated with HIV-1 dual infection.

AIDS 2016 11;30(17):2591-2597

aUniversity of California, San Diego, La Jolla, California, USA bINSERM UMR U966, Tours, France cVeterans Affairs San Diego Healthcare System, San Diego, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083206PMC
http://dx.doi.org/10.1097/QAD.0000000000001237DOI Listing
November 2016

Update and New Directions in Therapeutics for Neurological Complications of HIV Infections.

Neurotherapeutics 2016 07;13(3):471-6

University of California San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1007/s13311-016-0454-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965416PMC
July 2016

Antiretroviral therapy reduces neurodegeneration in HIV infection.

AIDS 2015 Jan;29(3):323-30

aHIV Neurobehavioral Research Center, University of California San Diego bDepartment of Psychiatry cDepartment of Neurosciences dDepartment of Pathology, University of California San Diego, La Jolla, San Diego, California, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353640PMC
January 2015

Methamphetamine Exposure Combined with HIV-1 Disease or gp120 Expression: Comparison of Learning and Executive Functions in Humans and Mice.

Neuropsychopharmacology 2015 Jul 5;40(8):1899-909. Epub 2015 Feb 5.

Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/npp.2015.39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839513PMC
July 2015

Plasma and Cerebrospinal Fluid Biomarkers Predict Cerebral Injury in HIV-Infected Individuals on Stable Combination Antiretroviral Therapy.

J Acquir Immune Defic Syndr 2015 May;69(1):29-35

*Emory University, Atlanta, GA; †Indiana University, Indianapolis, IN; ‡University of California, San Diego, San Diego, CA; §University of California, Los Angeles, CA; ‖University of Rochester School of Medicine, Rochester, NY; ¶University of Colorado Medical Center, Denver, CO; #University of Pittsburgh, Pittsburgh, PA; **University of Hawaii, Honolulu, HI; ††University of Florida, Gainesville, FL; and ‡‡Tufts University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424074PMC
May 2015

Absence of neurocognitive effect of hepatitis C infection in HIV-coinfected people.

Neurology 2015 Jan 10;84(3):241-50. Epub 2014 Dec 10.

From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.

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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000115
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http://dx.doi.org/10.1212/WNL.0000000000001156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335996PMC
January 2015

Apathy is associated with white matter abnormalities in anterior, medial brain regions in persons with HIV infection.

J Clin Exp Neuropsychol 2014 2;36(8):854-66. Epub 2014 Oct 2.

a San Diego University/University of California, San Diego Joint Doctoral Program in Clinical Psychology , San Diego , CA , USA.

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http://dx.doi.org/10.1080/13803395.2014.950636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303236PMC
June 2015

Editorial commentary: protease inhibitor monotherapy: safe for the CNS in durably suppressed patients?

Authors:
Scott L Letendre

Clin Infect Dis 2014 Dec 11;59(11):1635-7. Epub 2014 Aug 11.

University of California, San Diego, California.

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http://dx.doi.org/10.1093/cid/ciu645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650774PMC
December 2014

Cytokine secretion from brain macrophages infected with human immunodeficiency virus in vitro and treated with raltegravir.

BMC Infect Dis 2014 Jul 11;14:386. Epub 2014 Jul 11.

Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA 92093-0603, USA.

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http://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-
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http://dx.doi.org/10.1186/1471-2334-14-386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227040PMC
July 2014

Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline.

Neurology 2014 Jun 9;82(23):2055-62. Epub 2014 May 9.

From the University of California (I.G., D.R.F., R.D., S.P.W., F.V., R.J.E., S.L.L., T.D.M., J.H.A., J.A.M., I.A., A.G., C.F.-N., D.M.S., R.K.H.), San Diego; the University of Washington (A.C.C., C.M.M.), Seattle; Washington University (D.B.C.), St. Louis, MO; University of Texas Medical Branch (B.B.G.), Galveston; Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.

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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000049
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http://dx.doi.org/10.1212/WNL.0000000000000492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118496PMC
June 2014

Visual function assessment in simulated real-life situations in HIV-infected subjects.

PLoS One 2014 8;9(5):e97023. Epub 2014 May 8.

Department of Ophthalmology, Jacobs Retina Center at Shiley Eye Center, University of California San Diego, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097023PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014600PMC
June 2015

The veterans aging cohort study index is associated with concurrent risk for neurocognitive impairment.

J Acquir Immune Defic Syndr 2014 Feb;65(2):190-7

Departments of *Psychiatry; †Medicine; and ‡Neurosciences, University of California, San Diego, San Diego, CA.

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http://dx.doi.org/10.1097/QAI.0000000000000008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907119PMC
February 2014

Real-world impact of neurocognitive deficits in acute and early HIV infection.

J Neurovirol 2013 Dec 26;19(6):565-73. Epub 2013 Nov 26.

Joint Doctoral Program in Clinical Psychology, San Diego State University and University of California, San Diego, CA, USA.

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http://dx.doi.org/10.1007/s13365-013-0218-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865175PMC
December 2013