Publications by authors named "Scott J Hultgren"

200 Publications

Adaptation of Arginine Synthesis among Uropathogenic Branches of the Escherichia coli Phylogeny Reveals Adjustment to the Urinary Tract Habitat.

mBio 2020 09 29;11(5). Epub 2020 Sep 29.

Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, Missouri, USA

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September 2020

Urinary tract infections: microbial pathogenesis, host-pathogen interactions and new treatment strategies.

Nat Rev Microbiol 2020 04 18;18(4):211-226. Epub 2020 Feb 18.

Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.

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April 2020

High-resolution imaging reveals microbial biofilms on patient urinary catheters despite antibiotic administration.

World J Urol 2020 Sep 2;38(9):2237-2245. Epub 2019 Dec 2.

Division of Urologic Surgery, Department of Surgery, Washington University School of Medicine, 4960 Children's Place, Box 8242, St. Louis, MO, 63110-1093, USA.

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September 2020

Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence.

Elife 2019 08 20;8. Epub 2019 Aug 20.

Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St Louis, United States.

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August 2019

Insights into the Microbiome of Breast Implants and Periprosthetic Tissue in Breast Implant-Associated Anaplastic Large Cell Lymphoma.

Sci Rep 2019 07 17;9(1):10393. Epub 2019 Jul 17.

Division of Plastic & Reconstructive Surgery, Washington University School of Medicine, Alvin J. Siteman Cancer Center, Saint Louis, Missouri, USA.

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July 2019

Fimbriae reprogram host gene expression - Divergent effects of P and type 1 fimbriae.

PLoS Pathog 2019 06 10;15(6):e1007671. Epub 2019 Jun 10.

Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Klinikgatan, Lund, Sweden.

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June 2019

Reaching the End of the Line: Urinary Tract Infections.

Microbiol Spectr 2019 05;7(3)

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.

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May 2019

The Detection of Bacteria and Matrix Proteins on Clinically Benign and Pathologic Implants.

Plast Reconstr Surg Glob Open 2019 Feb 8;7(2):e2037. Epub 2019 Feb 8.

Division of Plastic & Reconstructive Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Mo.

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February 2019

Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner.

PLoS Pathog 2018 12 13;14(12):e1007457. Epub 2018 Dec 13.

Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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December 2018

Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC): Optimization through Iterative Rational Drug Design.

J Med Chem 2019 01 2;62(2):467-479. Epub 2019 Jan 2.

Department of Biochemistry and Molecular Biophysics , Washington University School of Medicine , St. Louis , Missouri 63110 , United States.

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January 2019

Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli.

Nat Microbiol 2018 12 1;3(12):1362-1368. Epub 2018 Oct 1.

Department of Molecular Microbiology, Washington University in St Louis, St Louis, MO, USA.

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December 2018

Manganese acquisition is essential for virulence of Enterococcus faecalis.

PLoS Pathog 2018 09 20;14(9):e1007102. Epub 2018 Sep 20.

Department of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, United States of America.

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September 2018

Differential Regulation of Genes following Binding to Mannose Receptors.

J Pathog 2018 22;2018:2897581. Epub 2018 May 22.

Center for Women's Infectious Disease Research, Washington University, St. Louis, MO 63110, USA.

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May 2018

Hydrogen Sulfide Sensing through Reactive Sulfur Species (RSS) and Nitroxyl (HNO) in Enterococcus faecalis.

ACS Chem Biol 2018 06 17;13(6):1610-1620. Epub 2018 May 17.

Department of Chemistry , Indiana University , Bloomington , Indiana 47405-7102 , United States.

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June 2018

Precision antimicrobial therapeutics: the path of least resistance?

NPJ Biofilms Microbiomes 2018 27;4. Epub 2018 Feb 27.

2Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110 USA.

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February 2018

Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.

Proc Natl Acad Sci U S A 2018 03 5;115(12):E2819-E2828. Epub 2018 Mar 5.

Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110;

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March 2018

Narrowing the spectrum: the new frontier of precision antimicrobials.

Genome Med 2017 Dec 14;9(1):110. Epub 2017 Dec 14.

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.

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December 2017

Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection.

NPJ Biofilms Microbiomes 2017 6;3:28. Epub 2017 Nov 6.

Department of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, Saint Louis, MO 63110-1093 USA.

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November 2017

Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions.

PLoS Negl Trop Dis 2017 May 22;11(5):e0005586. Epub 2017 May 22.

Molecular Microbiology and Microbial Pathogenesis Program, Division of Biology and Biomedical Sciences, Washington University School of Medicine, Saint Louis, Missouri, United States of America.

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May 2017

Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.

Sci Adv 2017 Feb 10;3(2):e1601944. Epub 2017 Feb 10.

Center for Women's Infectious Disease Research, Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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February 2017