Scott J Hebbring

Scott J Hebbring

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Scott J Hebbring

Scott J Hebbring

Publications by authors named "Scott J Hebbring"

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Ancestry-specific polygenic scores and SNP heritability of 25(OH)D in African- and European-ancestry populations.

Hum Genet 2019 Oct 24;138(10):1155-1169. Epub 2019 Jul 24.

Department of Population Health Sciences, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53706, USA.

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http://dx.doi.org/10.1007/s00439-019-02049-xDOI Listing
October 2019

Relationship of SULT1A1 copy number variation with estrogen metabolism and human health.

J Steroid Biochem Mol Biol 2017 11 1;174:169-175. Epub 2017 Sep 1.

Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, WI, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09600760173024
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http://dx.doi.org/10.1016/j.jsbmb.2017.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675753PMC
November 2017

RNA-Binding Protein IGF2BP1 in Cutaneous Squamous Cell Carcinoma.

J Invest Dermatol 2017 03 14;137(3):772-775. Epub 2016 Nov 14.

Department of Dermatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA; Department of Pediatrics, Pennsylvania State University, Hershey, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.10.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326591PMC
March 2017

The Decay of Disease Association with Declining Linkage Disequilibrium: A Fine Mapping Theorem.

Front Genet 2016 12;7:217. Epub 2016 Dec 12.

Center for Human Genetics, Marshfield Clinic Research FoundationMarshfield, WI, USA; Computation and Informatics in Biology and Medicine, University of Wisconsin-MadisonMadison, WI, USA.

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http://dx.doi.org/10.3389/fgene.2016.00217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149547PMC
December 2016

Mining Retrospective Data for Virtual Prospective Drug Repurposing: L-DOPA and Age-related Macular Degeneration.

Am J Med 2016 Mar 30;129(3):292-8. Epub 2015 Oct 30.

Department of Ophthalmology and Vision Science, University of Arizona, Tucson; Department of Cellular and Molecular Medicine, University of Arizona, Tucson. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2015.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841631PMC
March 2016

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

Authors:
Lars G Fritsche Wilmar Igl Jessica N Cooke Bailey Felix Grassmann Sebanti Sengupta Jennifer L Bragg-Gresham Kathryn P Burdon Scott J Hebbring Cindy Wen Mathias Gorski Ivana K Kim David Cho Donald Zack Eric Souied Hendrik P N Scholl Elisa Bala Kristine E Lee David J Hunter Rebecca J Sardell Paul Mitchell Joanna E Merriam Valentina Cipriani Joshua D Hoffman Tina Schick Yara T E Lechanteur Robyn H Guymer Matthew P Johnson Yingda Jiang Chloe M Stanton Gabriëlle H S Buitendijk Xiaowei Zhan Alan M Kwong Alexis Boleda Matthew Brooks Linn Gieser Rinki Ratnapriya Kari E Branham Johanna R Foerster John R Heckenlively Mohammad I Othman Brendan J Vote Helena Hai Liang Emmanuelle Souzeau Ian L McAllister Timothy Isaacs Janette Hall Stewart Lake David A Mackey Ian J Constable Jamie E Craig Terrie E Kitchner Zhenglin Yang Zhiguang Su Hongrong Luo Daniel Chen Hong Ouyang Ken Flagg Danni Lin Guanping Mao Henry Ferreyra Klaus Stark Claudia N von Strachwitz Armin Wolf Caroline Brandl Guenther Rudolph Matthias Olden Margaux A Morrison Denise J Morgan Matthew Schu Jeeyun Ahn Giuliana Silvestri Evangelia E Tsironi Kyu Hyung Park Lindsay A Farrer Anton Orlin Alexander Brucker Mingyao Li Christine A Curcio Saddek Mohand-Saïd José-Alain Sahel Isabelle Audo Mustapha Benchaboune Angela J Cree Christina A Rennie Srinivas V Goverdhan Michelle Grunin Shira Hagbi-Levi Peter Campochiaro Nicholas Katsanis Frank G Holz Frédéric Blond Hélène Blanché Jean-François Deleuze Robert P Igo Barbara Truitt Neal S Peachey Stacy M Meuer Chelsea E Myers Emily L Moore Ronald Klein Michael A Hauser Eric A Postel Monique D Courtenay Stephen G Schwartz Jaclyn L Kovach William K Scott Gerald Liew Ava G Tan Bamini Gopinath John C Merriam R Theodore Smith Jane C Khan Humma Shahid Anthony T Moore J Allie McGrath Reneé Laux Milam A Brantley Anita Agarwal Lebriz Ersoy Albert Caramoy Thomas Langmann Nicole T M Saksens Eiko K de Jong Carel B Hoyng Melinda S Cain Andrea J Richardson Tammy M Martin John Blangero Daniel E Weeks Bal Dhillon Cornelia M van Duijn Kimberly F Doheny Jane Romm Caroline C W Klaver Caroline Hayward Michael B Gorin Michael L Klein Paul N Baird Anneke I den Hollander Sascha Fauser John R W Yates Rando Allikmets Jie Jin Wang Debra A Schaumberg Barbara E K Klein Stephanie A Hagstrom Itay Chowers Andrew J Lotery Thierry Léveillard Kang Zhang Murray H Brilliant Alex W Hewitt Anand Swaroop Emily Y Chew Margaret A Pericak-Vance Margaret DeAngelis Dwight Stambolian Jonathan L Haines Sudha K Iyengar Bernhard H F Weber Gonçalo R Abecasis Iris M Heid

Nat Genet 2016 Feb 21;48(2):134-43. Epub 2015 Dec 21.

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/ng.3448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745342PMC
February 2016

The phenotypic legacy of admixture between modern humans and Neandertals.

Science 2016 Feb;351(6274):737-41

Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA. Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA. Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA. Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1126/science.aad2149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849557PMC
February 2016

Application of clinical text data for phenome-wide association studies (PheWASs).

Bioinformatics 2015 Jun 4;31(12):1981-7. Epub 2015 Feb 4.

Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA and Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA.

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http://dx.doi.org/10.1093/bioinformatics/btv076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481696PMC
June 2015

Phenome-wide association studies (PheWASs) for functional variants.

Eur J Hum Genet 2015 Apr 30;23(4):523-9. Epub 2014 Jul 30.

1] Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, WI, USA [2] Computation and Informatics in Biology and Medicine, University of Wisconsin Madison, Madison, WI, USA.

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http://dx.doi.org/10.1038/ejhg.2014.123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666492PMC
April 2015

SeqHBase: a big data toolset for family based sequencing data analysis.

J Med Genet 2015 Apr 13;52(4):282-8. Epub 2015 Jan 13.

Utah Foundation for Biomedical Research, Provo, Utah, USA Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California, USA Department of Psychiatry, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1136/jmedgenet-2014-102907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382803PMC
April 2015

Opportunities for drug repositioning from phenome-wide association studies.

Nat Biotechnol 2015 Apr;33(4):342-5

1] Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA. [2] Biomedical Statistics and Bioinformatics, Mayo Clinic, Rochester, Minnesota, USA and Nationwide Children's Hospital, Columbus, Ohio, USA.

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http://dx.doi.org/10.1038/nbt.3183DOI Listing
April 2015

Use of an electronic medical record to create the marshfield clinic twin/multiple birth cohort.

Genet Epidemiol 2014 Dec 22;38(8):692-8. Epub 2014 Sep 22.

Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, United States of America.

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http://doi.wiley.com/10.1002/gepi.21855
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http://dx.doi.org/10.1002/gepi.21855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384889PMC
December 2014

Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity.

Circ Res 2014 Dec 17;115(12):1017-25. Epub 2014 Oct 17.

From the Center for Pharmacogenomics, College of Medicine, The Ohio State University, Columbus (E.S.B., J.K.P., W.S.); Department of Human Genetics, Emory University School of Medicine, Atlanta, GA (D.W., J.F.C.); Center for Systems Genomics, Pennsylvania State University, University Park (A.V., S.A.P., M.D.R.); Department of Genetics, University of North Carolina School of Medicine, Chapel Hill (L.A.L.); Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson (J.G.W.); The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, PA (H.K., G.T., D.J.C.); Institute for Personalized Medicine, The Pennsylvania State University College of Medicine, Hershey (G.S.G.); Center for Human Genetics, Marshfield Clinic Research Foundation, WI (M.H.B., S.J.H.); and Department of Psychology, The University of Chicago, IL (G.J.N.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258174PMC
December 2014

The challenges, advantages and future of phenome-wide association studies.

Authors:
Scott J Hebbring

Immunology 2014 Feb;141(2):157-65

Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, WI, USA.

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http://dx.doi.org/10.1111/imm.12195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904236PMC
February 2014

Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization.

J Neurochem 2012 Mar 6;120(6):881-90. Epub 2012 Feb 6.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2012.07646.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296836PMC
March 2012

Copy number variation and cytidine analogue cytotoxicity: a genome-wide association approach.

BMC Genomics 2010 Jun 4;11:357. Epub 2010 Jun 4.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1186/1471-2164-11-357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894803PMC
June 2010

Polymorphisms in mitochondrial genes and prostate cancer risk.

Cancer Epidemiol Biomarkers Prev 2008 Dec;17(12):3558-66

Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-08-0434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750891PMC
December 2008

Glutathione S-transferase T1 and M1: gene sequence variation and functional genomics.

Clin Cancer Res 2007 Dec;13(23):7207-16

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-07-0635DOI Listing
December 2007

Two common chromosome 8q24 variants are associated with increased risk for prostate cancer.

Cancer Res 2007 Apr;67(7):2944-50

Departments of Laboratory Medicine and Pathology, Health Sciences Research, and Urology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3186DOI Listing
April 2007

Human SULT1A1 gene: copy number differences and functional implications.

Hum Mol Genet 2007 Mar 22;16(5):463-70. Epub 2006 Dec 22.

Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1093/hmg/ddl468DOI Listing
March 2007

Polymorphisms in genes involved in sex hormone metabolism may increase risk of benign prostatic hyperplasia.

Prostate 2006 Mar;66(4):392-404

Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1002/pros.20362DOI Listing
March 2006

Nonparametric tests of association of multiple genes with human disease.

Am J Hum Genet 2005 May 22;76(5):780-93. Epub 2005 Mar 22.

Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297076072
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http://dx.doi.org/10.1086/429838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199368PMC
May 2005

Polymorphisms in the 5alpha reductase type 2 gene and urologic measures of BPH.

Prostate 2005 Mar;62(4):380-7

Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1002/pros.20142DOI Listing
March 2005

Gluthatione-S-transferase P1 polymorphism I105V in familial and sporadic prostate cancer.

Cancer Genet Cytogenet 2004 Nov;155(1):82-6

Department of Urology, Mayo Clinic College of Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.cancergencyto.2004.03.015DOI Listing
November 2004

Androgen receptor gene polymorphisms and increased risk of urologic measures of benign prostatic hyperplasia.

Am J Epidemiol 2004 Feb;159(3):269-76

Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1093/aje/kwh042DOI Listing
February 2004