Publications by authors named "Scott D Emr"

93Publications

Membrane Protein Quality Control Mechanisms in the Endo-Lysosome System.

Trends Cell Biol 2021 Jan 4. Epub 2021 Jan 4.

Weill Institute of Cell and Molecular Biology, Cornell University, Ithaca, NY, USA; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA. Electronic address:

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January 2021

Calcineurin-dependent regulation of endocytosis by a plasma membrane ubiquitin ligase adaptor, Rcr1.

J Cell Biol 2020 Aug;219(8)

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY.

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August 2020

ESCRT-III and ER-PM contacts maintain lipid homeostasis.

Mol Biol Cell 2020 06 8;31(12):1302-1313. Epub 2020 Apr 8.

Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853.

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June 2020

Activity of a ubiquitin ligase adaptor is regulated by disordered insertions in its arrestin domain.

Mol Biol Cell 2019 12 16;30(25):3057-3072. Epub 2019 Oct 16.

Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853.

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December 2019

A bipartite sorting signal ensures specificity of retromer complex in membrane protein recycling.

J Cell Biol 2019 09 23;218(9):2876-2886. Epub 2019 Jul 23.

Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY

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September 2019

Genetic and Biochemical Analyses of Yeast ESCRT.

Methods Mol Biol 2019 ;1998:105-116

Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.

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March 2020

Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly.

Elife 2019 06 27;8. Epub 2019 Jun 27.

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, United States.

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June 2019

Methods for studying the regulation of membrane traffic by ubiquitin and the ESCRT pathway.

Methods Enzymol 2019 4;619:269-291. Epub 2019 Feb 4.

Weill Institute for Cell and Molecular Biology, Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, United States.

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February 2020

Rsp5 Ubiquitin ligase-mediated quality control system clears membrane proteins mistargeted to the vacuole membrane.

J Cell Biol 2019 01 25;218(1):234-250. Epub 2018 Oct 25.

Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY

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January 2019

Retrograde trafficking from the vacuole/lysosome membrane.

Autophagy 2018 17;14(9):1654-1655. Epub 2018 Aug 17.

a Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics , Cornell University , Ithaca, New York , USA.

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October 2019

Membrane protein recycling from the vacuole/lysosome membrane.

J Cell Biol 2018 05 6;217(5):1623-1632. Epub 2018 Mar 6.

Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY

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May 2018

ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins.

Elife 2017 06 29;6. Epub 2017 Jun 29.

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, United States.

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June 2017

Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs.

Mol Biol Cell 2017 May 15;28(9):1271-1283. Epub 2017 Mar 15.

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853

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May 2017

Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex.

Mol Biol Cell 2016 12 19;27(25):4043-4054. Epub 2016 Oct 19.

Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853

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December 2016

ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis.

Elife 2016 04 13;5. Epub 2016 Apr 13.

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, United States.

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April 2016

Phosphoinositide kinase signaling controls ER-PM cross-talk.

Mol Biol Cell 2016 Apr 10;27(7):1170-80. Epub 2016 Feb 10.

MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, United Kingdom Weill Institute for Cell and Molecular Biology, Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853

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April 2016

Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments.

Elife 2015 Dec 15;4. Epub 2015 Dec 15.

Weill Institute of Cell and Molecular Biology, Cornell University, Ithaca, United States.

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December 2015

Membrane-anchored ubiquitin ligase complex is required for the turnover of lysosomal membrane proteins.

J Cell Biol 2015 Nov 2;211(3):639-52. Epub 2015 Nov 2.

Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853

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November 2015

Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein.

J Cell Biol 2015 Aug;210(4):541-51

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853 Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853

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August 2015

Molecular mechanisms of inter-organelle ER-PM contact sites.

Curr Opin Cell Biol 2015 Aug 27;35:123-30. Epub 2015 May 27.

Weill Institute for Cell & Molecular Biology, Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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August 2015

Ubiquitin-dependent lysosomal membrane protein sorting and degradation.

Mol Cell 2015 Feb 22;57(3):467-78. Epub 2015 Jan 22.

Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, 14853, USA. Electronic address:

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February 2015

A Nobel Prize for membrane traffic: vesicles find their journey's end.

J Cell Biol 2013 Nov 8;203(4):559-61. Epub 2013 Nov 8.

Genentech, South San Francisco, CA 94080.

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November 2013

Essential N-terminal insertion motif anchors the ESCRT-III filament during MVB vesicle formation.

Dev Cell 2013 Oct 17;27(2):201-214. Epub 2013 Oct 17.

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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October 2013

Molecular mechanisms of the membrane sculpting ESCRT pathway.

Cold Spring Harb Perspect Biol 2013 Sep 1;5(9). Epub 2013 Sep 1.

Weill Institute for Cell and Molecular Biology, Cornell University, Weill Hall, Ithaca, New York 14853, USA.

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September 2013

The phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesis.

J Biol Chem 2013 Jul 3;288(28):20633-45. Epub 2013 Jun 3.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA.

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July 2013

ER-PM connections: sites of information transfer and inter-organelle communication.

Curr Opin Cell Biol 2013 Aug 20;25(4):434-42. Epub 2013 Mar 20.

Weill Institute for Cell & Molecular Biology, Department of Molecular Biology & Genetics, Cornell University, Ithaca, NY 14853, United States.

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August 2013

ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology.

Dev Cell 2012 Dec;23(6):1129-40

Weill Institute for Cell and Molecular Biology, Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.

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December 2012

The endosomal sorting complex ESCRT-II mediates the assembly and architecture of ESCRT-III helices.

Cell 2012 Oct;151(2):356-71

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

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October 2012

The dual PH domain protein Opy1 functions as a sensor and modulator of PtdIns(4,5)P₂ synthesis.

EMBO J 2012 Jun 4;31(13):2882-94. Epub 2012 May 4.

Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.

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June 2012

Ubiquitin and membrane protein turnover: from cradle to grave.

Annu Rev Biochem 2012 8;81:231-59. Epub 2012 Mar 8.

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York 14853, USA.

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August 2012

Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation.

EMBO Rep 2012 Apr;13(4):331-8

Molecular Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52246, USA.

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April 2012

Eisosome proteins assemble into a membrane scaffold.

J Cell Biol 2011 Nov;195(5):889-902

Organelle Architecture and Dynamics, Max Planck Institute of Biochemistry, D-82152 Martinsried, Germany.

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November 2011

TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor.

Cell 2011 Nov;147(5):1104-17

Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

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November 2011

Two novel WD40 domain-containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway.

Mol Biol Cell 2011 Nov 31;22(21):4093-107. Epub 2011 Aug 31.

Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.

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November 2011

Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis.

Biol Chem 2011 Aug;392(8-9):699-712

Division of Biochemistry and Molecular Biology, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3202, USA.

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August 2011

The ESCRT pathway.

Dev Cell 2011 Jul;21(1):77-91

Weill Institute for Cell and Molecular Biology, Cornell University, Weill Hall, Ithaca, NY 14853, USA.

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July 2011

Phosphoinositide [PI(3,5)P2] lipid-dependent regulation of the general transcriptional regulator Tup1.

Genes Dev 2011 May;25(9):984-95

Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA.

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May 2011

Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites.

Cell 2011 Feb;144(3):389-401

Weill Institute for Cell & Molecular Biology, Department of Molecular Biology & Genetics, Cornell University, Ithaca, NY 14853, USA.

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February 2011

Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling.

Proc Natl Acad Sci U S A 2010 Jun 14;107(26):11805-10. Epub 2010 Jun 14.

Division of Biochemistry and Molecular Biology, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3202, USA.

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June 2010

Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function.

EMBO J 2010 May 13;29(9):1489-98. Epub 2010 Apr 13.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.

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May 2010

SnapShot: the ESCRT machinery.

Cell 2009 Apr;137(1):182-182.e1

Cornell University, Ithaca, NY 14853, USA.

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April 2009

ESCRTs and human disease.

Biochem Soc Trans 2009 Feb;37(Pt 1):167-72

Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, 441 Weill Hall, Cornell University, Ithaca, NY 14853, USA.

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February 2009

Functional reconstitution of ESCRT-III assembly and disassembly.

Cell 2009 Jan;136(1):97-109

Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Weill Hall, Cornell University, Ithaca, NY 14853, USA.

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January 2009

Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3.

J Cell Biol 2008 Dec;183(6):1061-74

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

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December 2008

Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface.

Cell 2008 Nov 30;135(4):714-25. Epub 2008 Oct 30.

Department of Cellular and Molecular Medicine, Howard Hughes Medical Institute, University of California, San Diego, La Jolla, CA 92093, USA.

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November 2008

Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation.

Dev Cell 2008 Oct;15(4):578-89

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

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October 2008

Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase.

Mol Biol Cell 2008 Oct 23;19(10):4273-86. Epub 2008 Jul 23.

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

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October 2008

Novel Ist1-Did2 complex functions at a late step in multivesicular body sorting.

Mol Biol Cell 2008 Feb 21;19(2):475-84. Epub 2007 Nov 21.

Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA.

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February 2008

ESCRTing proteins in the endocytic pathway.

Trends Biochem Sci 2007 Dec 7;32(12):561-73. Epub 2007 Nov 7.

Cornell Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

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December 2007

Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4.

Nature 2007 Oct;449(7163):735-9

MRC Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge CB2 0QH, UK.

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October 2007

Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphate.

Mol Biol Cell 2007 Nov 15;18(11):4232-44. Epub 2007 Aug 15.

Department of Cellular and Molecular Medicine, Cornell Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

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November 2007

Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies.

Biochem Soc Symp 2007 (74):47-57

MRC Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, CB2 2QH, UK.

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July 2007

Structural insight into the ESCRT-I/-II link and its role in MVB trafficking.

EMBO J 2007 Jan 11;26(2):600-12. Epub 2007 Jan 11.

MRC Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK.

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January 2007

New component of ESCRT-I regulates endosomal sorting complex assembly.

J Cell Biol 2006 Dec;175(5):815-23

Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

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December 2006

TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF.

Nat Cell Biol 2006 Nov 15;8(11):1263-9. Epub 2006 Oct 15.

Department of Biological Sciences, Laboratory for Molecular Biology, University of Illinois at Chicago, Molecular Biology Research Building, 900 South Ashland Avenue, Chicago, IL 60607, USA.

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November 2006

The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation.

Mol Cell Biol 2006 Aug;26(15):5861-75

Department of Cellular and Molecular Medicine and Howard Hughes Medical Institute, University of California, San Diego, School of Medicine, La Jolla, CA 92093-0668, USA.

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August 2006

The ESCRT complexes: structure and mechanism of a membrane-trafficking network.

Annu Rev Biophys Biomol Struct 2006 ;35:277-98

Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, Maryland 20892-0580, USA.

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July 2006

Structural and functional organization of the ESCRT-I trafficking complex.

Cell 2006 Apr;125(1):113-26

Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA.

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April 2006

ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes.

Cell 2006 Apr;125(1):99-111

MRC Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, CB2 2QH, United Kingdom.

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April 2006

PtdIns(3)P accumulation in triple lipid-phosphatase-deletion mutants triggers lethal hyperactivation of the Rho1p/Pkc1p cell-integrity MAP kinase pathway.

J Cell Sci 2005 Dec;118(Pt 23):5589-601

Department of Cellular and Molecular Medicine and the Howard Hughes Medical Institute, University of California at San Diego, School of Medicine, La Jolla, California 92093-0668, USA.

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December 2005

Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis.

J Cell Sci 2005 Oct;118(Pt 20):4751-64

Division of Biology, Department of Cellular and Molecular Medicine, and the Howard Hughes Medical Institute, University of California, San Diego, La Jolla, CA 92093-0668, USA.

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October 2005

The Fab1 phosphatidylinositol kinase pathway in the regulation of vacuole morphology.

Curr Opin Cell Biol 2005 Aug;17(4):402-8

Division of Biology, Department of Cellular and Molecular Medicine, and the Howard Hughes Medical Institute, University of California-San Diego, La Jolla, CA 92093-0668, USA.

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August 2005

The phosphoinositide phosphatase Sjl2 is recruited to cortical actin patches in the control of vesicle formation and fission during endocytosis.

Mol Cell Biol 2005 Apr;25(8):2910-23

Department of Cellular and Molecular Medicine, The Howard Hughes Medical Institute, University of California, San Diego, School of Medicine, La Jolla, CA 92093-0068, USA.

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April 2005

Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking.

Proc Natl Acad Sci U S A 2005 Mar 21;102(13):4866-71. Epub 2005 Mar 21.

Department of Microbiology, Columbia University Medical Center, 701 West 168th Street, New York, NY 10032, USA.

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March 2005

Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway.

Mol Biol Cell 2005 Feb 1;16(2):776-93. Epub 2004 Dec 1.

Department of Cellular and Molecular Medicine, Howard Hughes Medical Institute, School of Medicine, University of California at San Diego, La Jolla, CA 92093-0668, USA.

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February 2005

Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway.

J Biol Chem 2004 Dec 30;279(49):51022-32. Epub 2004 Sep 30.

Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-8240, USA.

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December 2004

Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.

EMBO J 2004 Oct 16;23(19):3747-57. Epub 2004 Sep 16.

Department of Cellular and Molecular Medicine, The Howard Hughes Medical Institute, University of California, San Diego School of Medicine, La Jolla, CA, USA.

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October 2004

Structure of the ESCRT-II endosomal trafficking complex.

Nature 2004 Sep 25;431(7005):221-5. Epub 2004 Aug 25.

Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland 20892-0580, USA.

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September 2004

Essential role for the myotubularin-related phosphatase Ymr1p and the synaptojanin-like phosphatases Sjl2p and Sjl3p in regulation of phosphatidylinositol 3-phosphate in yeast.

Mol Biol Cell 2004 Aug 28;15(8):3567-79. Epub 2004 May 28.

Department of Cellular and Molecular Medicine and the Howard Hughes Medical Institute, School of Medicine, University of California at San Diego, La Jolla, California 92093-0668, USA.

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August 2004

Ubiquitin interactions of NZF zinc fingers.

EMBO J 2004 Apr 18;23(7):1411-21. Epub 2004 Mar 18.

Department of Biochemistry, University of Utah, Salt Lake City, UT, USA.

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April 2004

Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains.

Mol Cell 2004 Mar;13(5):677-88

Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 USA.

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March 2004

Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S.

Mol Biol Cell 2004 Feb 2;15(2):468-80. Epub 2003 Dec 2.

Department of Cellular and Molecular Medicine, Howard Hughes Medical Institute, University of California, San Diego, School of Medicine, La Jolla, California 92093-0668, USA.

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February 2004

Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase.

Mol Biol Cell 2004 Jan 3;15(1):24-36. Epub 2003 Oct 3.

Department of Cellular and Molecular Medicine, and the Howard Hughes Medical Institute, University of California at San Diego, School of Medicine, La Jolla, California 92093-0668, USA.

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January 2004

Regulation of PI4,5P2 synthesis by nuclear-cytoplasmic shuttling of the Mss4 lipid kinase.

EMBO J 2003 Aug;22(16):4223-36

Department of Cellular and Molecular Medicine, University of California, San Diego, School of Medicine, La Jolla, CA 92093-0668, USA.

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August 2003

Vps27 recruits ESCRT machinery to endosomes during MVB sorting.

J Cell Biol 2003 Aug;162(3):413-23

Department of Cellular and Molecular Medicine, and Howard Hughes Medical Institute, University of California, San Diego School of Medicine, La Jolla, CA 92093-0688, USA.

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August 2003

Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae.

J Cell Sci 2003 May 18;116(Pt 10):1893-903. Epub 2003 Mar 18.

Department of Molecular, Cellular and Developmental Biology, University of Colorado, Campus Box 347, Boulder, CO 80309, USA.

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May 2003

Receptor downregulation and multivesicular-body sorting.

Nat Rev Mol Cell Biol 2002 Dec;3(12):893-905

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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December 2002

Rothman and Schekman SNAREd by Lasker for trafficking.

Cell 2002 Oct;111(1):1-3

Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093, USA.

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October 2002

The Saccharomyces cerevisiae LSB6 gene encodes phosphatidylinositol 4-kinase activity.

J Biol Chem 2002 Dec 1;277(49):47709-18. Epub 2002 Oct 1.

Department of Food Science, Cook College, New Jersey Agricultural Experiment Station, Rutgers University, New Brunswick, New Jersey 08901, USA.

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December 2002

Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase.

J Cell Sci 2002 Oct;115(Pt 20):3889-900

Department of Cellular and Molecular Medicine and Howard Hughes Medical Institute, University of California at San Diego, School of Medicine, La Jolla, CA 92093-0668, USA.

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October 2002

Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body.

Dev Cell 2002 Aug;3(2):283-9

Department of Cellular and Molecular Medicine and Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla 92093, USA.

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August 2002

Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.

Dev Cell 2002 Aug;3(2):271-82

Department of Cellular and Molecular Medicine and Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla 92093, USA.

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August 2002

Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy.

J Cell Biol 2002 Aug 19;158(4):761-72. Epub 2002 Aug 19.

Department of Cellular and Molecular Medicine, Howard Hughes Medical Institute, University of California at San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.

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August 2002

Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy.

J Biol Chem 2002 Aug 4;277(33):30198-207. Epub 2002 Jun 4.

Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.

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August 2002

Stt4 PI 4-kinase localizes to the plasma membrane and functions in the Pkc1-mediated MAP kinase cascade.

Dev Cell 2002 May;2(5):593-605

Division of Cellular and Molecular Medicine, The Howard Hughes Medical Institute, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.

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May 2002

Endosomal localization and function of sorting nexin 1.

Proc Natl Acad Sci U S A 2002 May 7;99(10):6767-72. Epub 2002 May 7.

Department of Medicine, University of California at San Diego School of Medicine, La Jolla, CA 92093-0650, USA.

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May 2002

Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis.

Nat Cell Biol 2002 May;4(5):389-93

Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL, 60208-3500, USA.

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May 2002

Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member.

Mol Biol Cell 2002 Apr;13(4):1238-51

Department of Cellular and Molecular Medicine, University of California at San Diego, School of Medicine, La Jolla, CA 92093-0668, USA.

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April 2002

The yeast synaptojanin-like proteins control the cellular distribution of phosphatidylinositol (4,5)-bisphosphate.

Mol Biol Cell 2002 Feb;13(2):542-57

Division of Cellular and Molecular Medicine, The Howard Hughes Medical Institute, University of California, San Diego, School of Medicine, La Jolla, California 92093-0068, USA.

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February 2002