Scott C Howard

Scott C Howard

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Optimizing outcomes for children with non-Hodgkin lymphoma in low- and middle-income countries by early correct diagnosis, reducing toxic death and preventing abandonment.

Br J Haematol 2019 Jun 10;185(6):1125-1135. Epub 2019 Feb 10.

University of Tennessee Health Science Center, Memphis, TN, USA.

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http://dx.doi.org/10.1111/bjh.15785DOI Listing
June 2019

Science and health for all children with cancer.

Science 2019 Mar;363(6432):1182-1186

Board, International Society of Paediatric Oncology (SIOP), Zug, Switzerland.

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http://www.sciencemag.org/lookup/doi/10.1126/science.aaw4892
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http://dx.doi.org/10.1126/science.aaw4892DOI Listing
March 2019

Delivering modern anticancer therapies in low- and middle-income settings: We can be evidence based.

Pediatr Blood Cancer 2018 12 26;65(12):e27347. Epub 2018 Jul 26.

The University of Tennessee Health Science Center, Memphis, Tennessee.

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http://dx.doi.org/10.1002/pbc.27347DOI Listing
December 2018

Safe Use of Low-Molecular-weight Heparin in Pediatric Acute Lymphoblastic Leukemia and Lymphoma Around Lumbar Punctures.

J Pediatr Hematol Oncol 2017 11;39(8):596-601

*Department of Hematology †Department of Pathology §Department of Biostatistics, St. Jude Children's Research Hospital ‡Division of Epidemiology, Biostatistics, and Environmental Health, The University of Memphis School of Public Health ¶University of Tennessee Health Science Center, Memphis, Memphis, TN.

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http://dx.doi.org/10.1097/MPH.0000000000000988DOI Listing
November 2017

Managing Tumor Lysis Syndrome in the Era of Novel Cancer Therapies.

J Adv Pract Oncol 2017 Nov-Dec;8(7):705-720. Epub 2017 Nov 1.

University of Memphis, School of Health Studies, Memphis, Tennessee.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188097PMC
November 2017

Improvement in treatment abandonment in pediatric patients with cancer in Guatemala.

Pediatr Blood Cancer 2017 Oct 19;64(10). Epub 2017 Apr 19.

Division of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.

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http://dx.doi.org/10.1002/pbc.26560DOI Listing
October 2017

Assessing National Cancer Control Plan Knowledge, Prioritization, and Engagement Through a Pediatric Oncology Cancer Control Workshop.

J Pediatr Hematol Oncol 2017 07;39(5):362-364

*Children's Hospital and Medical Center, Omaha, NE †University of Tennessee Health Sciences Center ∥St. Jude Children's Research Hospital, Memphis, TN ‡Korle Bu Teaching Hospital, Accra, Ghana §Cheikh Khalifa Hospital, Casablanca, Morocco.

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http://dx.doi.org/10.1097/MPH.0000000000000835DOI Listing
July 2017

Prognostic significance of TRAIL-R3 and CCR-2 expression in tumor epithelial cells of patients with early breast cancer.

BMC Cancer 2017 04 18;17(1):280. Epub 2017 Apr 18.

Instituto de Biología y Medicina Experimental, Laboratorio de Inmunohematología (IBYME) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Vuelta de Obligado 2490, CP 1428, Ciudad Autónoma de Buenos Aires, Argentina.

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http://dx.doi.org/10.1186/s12885-017-3259-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395831PMC
April 2017

Hepatoblastoma and Abernethy Malformation Type I: Case Report.

J Pediatr Hematol Oncol 2017 03;39(2):e79-e81

*Instituto Nacional de Cancerología, Bogota, Colombia †School of Health Studies, University of Memphis, Memphis, TN.

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http://dx.doi.org/10.1097/MPH.0000000000000650DOI Listing
March 2017

Comparison of C-Methionine and F-FDG PET/CT for Staging and Follow-up of Pediatric Lymphoma.

J Nucl Med 2017 Mar 8;58(3):419-424. Epub 2016 Sep 8.

Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.2967/jnumed.116.178640DOI Listing
March 2017

Preventing and Managing Toxicities of High-Dose Methotrexate.

Oncologist 2016 12 5;21(12):1471-1482. Epub 2016 Aug 5.

Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1634/theoncologist.2015-0164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153332PMC
December 2016

Interleukin-6 receptor in spindle-shaped stromal cells, a prognostic determinant of early breast cancer.

Tumour Biol 2016 Oct 27;37(10):13377-13384. Epub 2016 Jul 27.

Laboratorio de Inmunohematología, Instituto de Biología y Medicina Experimental (IBYME) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Vuelta de Obligado 2490, CP 1428, Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.

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http://dx.doi.org/10.1007/s13277-016-5268-7DOI Listing
October 2016

A Framework for Adapted Nutritional Therapy for Children With Cancer in Low- and Middle-Income Countries: A Report From the SIOP PODC Nutrition Working Group.

Pediatr Blood Cancer 2016 08 15;63(8):1339-48. Epub 2016 Apr 15.

Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1002/pbc.26016DOI Listing
August 2016

Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia.

J Clin Oncol 2016 06 25;34(18):2133-40. Epub 2016 Apr 25.

Chengcheng Liu, Wenjian Yang, Cheng Cheng, Deqing Pei, Colton Smith, Sima Jeha, Ching-Hon Pui, William E. Evans, and Mary V. Relling, St Jude Children's Research Hospital; Scott C. Howard, University of Memphis, Memphis, TN; Meenakshi Devidas, University of Florida, Gainesville, FL; William L. Carroll, New York University Langone Medical Center, New York, NY; Elizabeth A. Raetz, University of Utah, Salt Lake City, UT; W. Paul Bowman, Cook Children's Hospital, Ft Worth; Naomi J. Winick, University of Texas Southwestern Medical Center, Dallas, TX; Eric C. Larsen, Maine Children's Cancer Program, Scarborough, ME; Kelly W. Maloney, University of Colorado Denver, Aurora, CO; Paul L. Martin, Duke University, Durham, NC; Leonard A. Mattano Jr, HARP Pharma Consulting, Mystic, CT; Elaine R. Mardis and Robert S. Fulton, The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO; Deepa Bhojwani, Children's Hospital of Los Angeles, Los Angeles; Mignon L. Loh, University of California San Francisco Medical Center-Parnassus, San Francisco, CA; and Stephen P. Hunger, Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.2015.64.5812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962704PMC
June 2016

Alert dwell time: introduction of a measure to evaluate interruptive clinical decision support alerts.

J Am Med Inform Assoc 2016 Apr 24;23(e1):e138-41. Epub 2015 Oct 24.

Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, Tennessee, USA Department of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA

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http://jamia.oxfordjournals.org/content/jaminfo/early/2015/1
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http://jamia.oxfordjournals.org/lookup/doi/10.1093/jamia/ocv
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http://dx.doi.org/10.1093/jamia/ocv144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954613PMC
April 2016

Tumor lysis syndrome in the era of novel and targeted agents in patients with hematologic malignancies: a systematic review.

Ann Hematol 2016 Mar 12;95(4):563-73. Epub 2016 Jan 12.

The University of Arizona Cancer Center, Tucson, AZ, USA.

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http://dx.doi.org/10.1007/s00277-015-2585-7DOI Listing
March 2016

Improving Care for Children With Cancer in Low- and Middle-Income Countries--a SIOP PODC Initiative.

Pediatr Blood Cancer 2016 Mar 24;63(3):387-91. Epub 2015 Nov 24.

Department of Pediatric Oncology - Outreach Program, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/pbc.25810DOI Listing
March 2016

Pregnancy-associated cardiomyopathy in survivors of childhood cancer.

J Cancer Surviv 2016 Feb 5;10(1):113-21. Epub 2015 Jun 5.

Department of Pediatrics, University of Tennessee Health Science Center, 50 N. Dunlap, Rm 461R, Memphis, TN, 38103, USA.

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http://dx.doi.org/10.1007/s11764-015-0457-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670599PMC
February 2016

Lung volume recruitment in a preterm pig model of lung immaturity.

Am J Physiol Lung Cell Mol Physiol 2015 Nov 25;309(10):L1088-92. Epub 2015 Sep 25.

School of Health Studies, University of Memphis, Memphis, Tennessee;

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http://dx.doi.org/10.1152/ajplung.00292.2015DOI Listing
November 2015

Supportive medical care for children with acute lymphoblastic leukemia in low- and middle-income countries.

Expert Rev Hematol 2015 Oct 26;8(5):613-26. Epub 2015 May 26.

a 1 Division of Hematology/Oncology, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1586/17474086.2015.1049594DOI Listing
October 2015

Infectious complications in children with acute lymphoblastic leukemia treated in low-middle-income countries.

Expert Rev Hematol 2015 Oct 27;8(5):627-45. Epub 2015 Jul 27.

a 1 Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1586/17474086.2015.1071186DOI Listing
October 2015

Interventions to improve adherence to treatment for paediatric tuberculosis in low- and middle-income countries: a systematic review and meta-analysis.

Bull World Health Organ 2015 Oct 23;93(10):700-711B. Epub 2015 Jun 23.

St Jude Children's Research Hospital, 262 Danny Thomas Place, MS 721, Memphis, TN 38105, United States of America (USA).

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http://dx.doi.org/10.2471/BLT.14.147231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645428PMC
October 2015

The weaned pig as a model for Doxorubicin-induced mucositis.

Chemotherapy 2014 21;60(1):24-36. Epub 2014 Oct 21.

Department of Health and Sport Sciences, University of Memphis, Memphis, Tenn., USA.

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http://dx.doi.org/10.1159/000365725DOI Listing
July 2015

Defining and distinguishing treatment abandonment in patients with cancer.

J Pediatr Hematol Oncol 2015 May;37(4):252-6

St Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.1097/MPH.0000000000000319DOI Listing
May 2015

A practical approach to reporting treatment abandonment in pediatric chronic conditions.

Pediatr Blood Cancer 2015 Apr 13;62(4):565-70. Epub 2015 Jan 13.

St Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1002/pbc.25403DOI Listing
April 2015

Utility of early screening magnetic resonance imaging for extensive hip osteonecrosis in pediatric patients treated with glucocorticoids.

J Clin Oncol 2015 Feb 20;33(6):610-5. Epub 2015 Jan 20.

Sue C. Kaste, Deqing Pei, Cheng Cheng, Michael D. Neel, Raul C. Ribeiro, Monika L. Metzger, Deepa Bhojwani, Hiroto Inaba, Patrick Campbell, Jeffrey E. Rubnitz, Sima Jeha, John T. Sandlund, James R. Downing, Mary V. Relling, Ching-Hon Pui, and Scott C. Howard, St Jude Children's Research Hospital; Sue C. Kaste, University of Tennessee Health Sciences Center, Memphis, TN; and W. Paul Bowman, Cook Children's Medical Center, Fort Worth, TX.

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http://dx.doi.org/10.1200/JCO.2014.57.5480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322260PMC
February 2015

Reported availability and gaps of pediatric palliative care in low- and middle-income countries: a systematic review of published data.

J Palliat Med 2014 Dec;17(12):1369-83

1 Center for Bioethics and Humanities, and Department of Pediatrics, SUNY Upstate Medical University , Syracuse, New York.

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http://dx.doi.org/10.1089/jpm.2014.0095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268583PMC
December 2014

Improved hydroxyurea effect with the use of text messaging in children with sickle cell anemia.

Pediatr Blood Cancer 2014 Nov 17;61(11):2031-6. Epub 2014 Aug 17.

Departments of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1002/pbc.25177DOI Listing
November 2014

Outcomes in patients with mixed phenotype acute leukemia in Morocco.

J Pediatr Hematol Oncol 2014 Aug;36(6):e392-7

*Laboratoire de cytométrie en flux, Institut National d'Hygiène †Unité d'hémato-oncologie pédiatrique (UHOP), Hôpital d'enfants, Rabat, Maroc ‡Service d'hématologie et oncologie pédiatrique, Hôpital, Casablanca, Maroc §Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.1097/MPH.0b013e31828e54a5DOI Listing
August 2014

Onco-nephrology: an invitation to a new field.

J Clin Oncol 2014 Aug 16;32(22):2389-90. Epub 2014 Jun 16.

St Jude Children's Research Hospital, University of Tennessee Health Science Center, Memphis, TN.

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http://ascopubs.org/doi/10.1200/JCO.2014.56.5622
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http://dx.doi.org/10.1200/JCO.2014.56.5622DOI Listing
August 2014

Outcome of children treated for relapsed acute myeloid leukemia in Central America.

Pediatr Blood Cancer 2014 Jul 17;61(7):1222-6. Epub 2014 Jan 17.

Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada; McMaster Children's Hospital, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1002/pbc.24942DOI Listing
July 2014

Feasibility, efficacy, and adverse effects of outpatient antibacterial prophylaxis in children with acute myeloid leukemia.

Cancer 2014 Jul 26;120(13):1985-92. Epub 2014 Mar 26.

Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee; Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.

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http://dx.doi.org/10.1002/cncr.28688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063871PMC
July 2014

Pediatric oncology as the next global child health priority: the need for national childhood cancer strategies in low- and middle-income countries.

PLoS Med 2014 Jun 17;11(6):e1001656. Epub 2014 Jun 17.

Division of Pediatric Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

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https://dx.plos.org/10.1371/journal.pmed.1001656
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http://dx.doi.org/10.1371/journal.pmed.1001656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061014PMC
June 2014

Methotrexate-induced neurotoxicity and leukoencephalopathy in childhood acute lymphoblastic leukemia.

J Clin Oncol 2014 Mar 18;32(9):949-59. Epub 2014 Feb 18.

All authors: St Jude Children's Research Hospital; and Deepa Bhojwani, Jun J. Yang, Hiroto Inaba, Jeffrey E. Rubnitz, Monika L. Metzger, Scott C. Howard, Raul C. Ribeiro, Sima Jeha, John T. Sandlund, and Ching-Hon Pui, University of Tennessee Health Sciences Center, College of Medicine, Memphis, TN.

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http://dx.doi.org/10.1200/JCO.2013.53.0808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948096PMC
March 2014

Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments.

Cancer Chemother Pharmacol 2013 Aug 13;72(2):369-78. Epub 2013 Jun 13.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA.

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http://dx.doi.org/10.1007/s00280-013-2206-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719000PMC
August 2013

POND4Kids: a global web-based database for pediatric hematology and oncology outcome evaluation and collaboration.

Stud Health Technol Inform 2013 ;183:251-6

International Outreach Program, St. Jude Children's Research Hospital, TN, USA.

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July 2013

Outcome of children treated for relapsed acute lymphoblastic leukemia in Central America.

Cancer 2013 Mar 16;119(6):1277-83. Epub 2012 Nov 16.

Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cncr.27846DOI Listing
March 2013

Paediatric cancer in low-income and middle-income countries.

Lancet Oncol 2013 Mar 20;14(3):e104-16. Epub 2013 Feb 20.

International Network for Cancer Treatment and Research, Brussels, Belgium.

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http://dx.doi.org/10.1016/S1470-2045(13)70008-1DOI Listing
March 2013

Management of children with brain tumors in Paraguay.

Neuro Oncol 2013 Feb 29;15(2):235-41. Epub 2012 Nov 29.

Children’s Center for Cancer and Blood Diseases, Children’s Hospital of Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1093/neuonc/nos291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548583PMC
February 2013

Treatment-related mortality in children with acute myeloid leukaemia in Central America: incidence, timing and predictors.

Eur J Cancer 2012 Jun 13;48(9):1363-9. Epub 2011 Nov 13.

Division of Haematology/Oncology and Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1016/j.ejca.2011.10.009DOI Listing
June 2012

Thrombolytic therapy for central venous catheter occlusion.

Haematologica 2012 May 16;97(5):641-50. Epub 2011 Dec 16.

Division of Hematology and Oncology, Children’s Hospital Los Angeles, Los Angeles, CA 90027, USA.

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http://www.haematologica.org/cgi/doi/10.3324/haematol.2011.0
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http://dx.doi.org/10.3324/haematol.2011.050492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342964PMC
May 2012

Pediatric oncology research in low income countries: ethical concepts and challenges.

Pediatr Blood Cancer 2012 Apr 6;58(4):492-7. Epub 2011 Dec 6.

Division of Haematology/Oncology, Department of Pediatric Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pbc.23419DOI Listing
April 2012

A sustainable model for pediatric oncology nursing education in low-income countries.

Pediatr Blood Cancer 2012 Feb 18;58(2):163-6. Epub 2011 Nov 18.

International Outreach Program, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://doi.wiley.com/10.1002/pbc.24007
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http://dx.doi.org/10.1002/pbc.24007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676073PMC
February 2012

Symptoms of attention-deficit/hyperactivity disorder in long-term survivors of childhood leukemia.

Pediatr Blood Cancer 2011 Dec 28;57(7):1191-6. Epub 2011 Jan 28.

Department of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1002/pbc.22994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140624PMC
December 2011

Treatment-related mortality in children with acute lymphoblastic leukemia in Central America.

Cancer 2011 Oct 28;117(20):4788-95. Epub 2011 Mar 28.

Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/cncr.26107
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http://dx.doi.org/10.1002/cncr.26107DOI Listing
October 2011

POND4Kids: a web-based pediatric cancer database for hospital-based cancer registration and clinical collaboration.

Stud Health Technol Inform 2011 ;164:227-31

International Outreach Program, St. Jude Children's Research Hospital, Memphis, TN, USA.

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June 2011

The tumor lysis syndrome.

N Engl J Med 2011 May;364(19):1844-54

Department of Oncology and International Outreach Program, St. Jude Children's Research Hospital, Memphis, TN 38105-2794, USA.

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http://dx.doi.org/10.1056/NEJMra0904569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437249PMC
May 2011

Safe and successful implementation of CPOE for chemotherapy at a children's cancer center.

J Natl Compr Canc Netw 2011 Feb;9 Suppl 3:S36-50

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, and the Department of Clinical Pharmacy, University of Tennessee Health Science Center, Colleges of Pharmacy and Medicine, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.6004/jnccn.2011.0131DOI Listing
February 2011

Changes in medical care at a pediatric oncology referral center after placement of a do-not-resuscitate order.

J Palliat Med 2010 Nov 30;13(11):1349-52. Epub 2010 Oct 30.

Department of Pediatric Medicine, Division of Palliative and End-of-Life Care, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://www.liebertpub.com/doi/10.1089/jpm.2010.0177
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http://dx.doi.org/10.1089/jpm.2010.0177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001240PMC
November 2010

Utility of bone marrow biopsy at diagnosis in pediatric Hodgkin's lymphoma.

Haematologica 2010 Oct 21;95(10):1691-6. Epub 2010 May 21.

Department of Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA.

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http://dx.doi.org/10.3324/haematol.2010.025072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948094PMC
October 2010

Severe thrombocytopenia with iron deficiency anemia.

Pediatr Hematol Oncol 2010 Aug;27(5):413-9

Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.3109/08880011003739455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439835PMC
August 2010

Conservative management of pancreatic pseudocysts in children with acute lymphoblastic leukemia.

J Pediatr Hematol Oncol 2009 Dec;31(12):957-9

Department of Oncology, St Jude Children's Research Hospital, Memphis, TN 38105, USA.

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https://insights.ovid.com/crossref?an=00043426-200912000-000
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http://dx.doi.org/10.1097/MPH.0b013e3181ba9e6aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811578PMC
December 2009