Dr. Sawa Kostin, MD, PhD - Max-Planck-Institute

Dr. Sawa Kostin

MD, PhD

Max-Planck-Institute

Bad Nauheim | Germany

ORCID logohttps://orcid.org/0000-0002-1594-9476

Dr. Sawa Kostin, MD, PhD - Max-Planck-Institute

Dr. Sawa Kostin

MD, PhD

Introduction

Primary Affiliation: Max-Planck-Institute - Bad Nauheim , Germany

Education

Max_planck-Institute for Heart and Lung Research
M.D., Ph.D.
Max-Planck-Institute for Heart and Lung Research
M.D., Ph.D.
Molecular and Structural Biology

Experience

Max-Planck-Institute for Heart and Lung Research
Head
Molecular and Structural Biology

Publications

93Publications

792Reads

164Profile Views

Human cardiomyocytes undergo enhanced maturation in embryonic stem cell-derived organoid transplants.

Biomaterials 2019 Feb 27;192:537-550. Epub 2018 Nov 27.

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran; Department of Developmental Biology, University of Science and Culture, Tehran, Iran. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612183081
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http://dx.doi.org/10.1016/j.biomaterials.2018.11.033DOI Listing
February 2019
14 Reads
8.557 Impact Factor

Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown.

Cell Rep 2018 May;23(5):1342-1356

Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; Center for Molecular Medicine (CMMC), University of Cologne, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.03.136DOI Listing
May 2018
9 Reads
7.210 Impact Factor

Human embryonic stem cell-derived cardiovascular progenitor cells efficiently colonize in bFGF-tethered natural matrix to construct contracting humanized rat hearts.

Biomaterials 2018 Feb 1;154:99-112. Epub 2017 Nov 1.

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran; Department of Developmental Biology, University of Science and Culture, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.10.054DOI Listing
February 2018
23 Reads
8.560 Impact Factor

The effects of polyunsaturated fatty acids and antioxidant vitamins on atrial oxidative stress, nitrotyrosine residues, and connexins following extracorporeal circulation in patients undergoing cardiac surgery.

Mol Cell Biochem 2017 Sep 23;433(1-2):27-40. Epub 2017 Mar 23.

Max-Planck-Institute for Heart and Lung Research, Ludwigstrasse 43, 61231, Bad Nauheim, Germany.

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http://dx.doi.org/10.1007/s11010-017-3013-1DOI Listing
September 2017
15 Reads
2.393 Impact Factor

Factor VII activating protease (FSAP) influences vascular remodeling in the mouse hind limb ischemia model.

Am J Transl Res 2017 15;9(6):3084-3095. Epub 2017 Jun 15.

Oslo University Hospital, University of OsloNorway.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489907PMC
June 2017
12 Reads
3.230 Impact Factor

Proteolysis regulates cardiomyocyte maturation and tissue integration.

Nat Commun 2017 02 17;8:14495. Epub 2017 Feb 17.

Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1038/ncomms14495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321751PMC
February 2017
21 Reads
10.742 Impact Factor

BRAF activates PAX3 to control muscle precursor cell migration during forelimb muscle development.

Elife 2016 12 1;5. Epub 2016 Dec 1.

Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany.

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http://dx.doi.org/10.7554/eLife.18351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148607PMC
December 2016
6 Reads
8.520 Impact Factor

Cardiac telocytes in normal and diseased hearts.

Authors:
Sawa Kostin

Semin Cell Dev Biol 2016 07 18;55:22-30. Epub 2016 Feb 18.

Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Ludwigstrasse 43, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2016.02.023DOI Listing
July 2016
25 Reads
6.265 Impact Factor

Cavin4b/Murcb Is Required for Skeletal Muscle Development and Function in Zebrafish.

PLoS Genet 2016 06 13;12(6):e1006099. Epub 2016 Jun 13.

Department of Biochemistry and Biophysics, University of California, San Francisco (UCSF), San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905656PMC
June 2016
11 Reads

Animal Models and "Omics" Technologies for Identification of Novel Biomarkers and Drug Targets to Prevent Heart Failure.

Biomed Res Int 2015 7;2015:212910. Epub 2015 Jul 7.

Department of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1155/2015/212910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508378PMC
May 2016
8 Reads

Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation.

Cell Stem Cell 2016 Feb 5;18(2):229-42. Epub 2015 Dec 5.

Max-Planck-Institute for Heart and Lung Research, Department of Cardiac Development and Remodeling, 61231 Bad Nauheim, Germany; Instituto de Investigacion en Biomedicina de Buenos Aires (IBioBA)-CONICET-Partner Institute of the Max Planck Society, C1425FQD Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.11.002DOI Listing
February 2016
36 Reads

The failing human heart is characterized by decreased numbers of telocytes as result of apoptosis and altered extracellular matrix composition.

J Cell Mol Med 2015 Nov 26;19(11):2597-606. Epub 2015 Aug 26.

Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany.

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http://dx.doi.org/10.1111/jcmm.12664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627565PMC
November 2015
14 Reads

Sca1-derived cells are a source of myocardial renewal in the murine adult heart.

Stem Cell Reports 2013 24;1(5):397-410. Epub 2013 Oct 24.

Max Planck Institute for Heart and Lung Research, Ludwigstr. 43, 61231 Bad Nauheim, Germany ; Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe-University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.stemcr.2013.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841250PMC
October 2015
15 Reads

Myostatin induces interstitial fibrosis in the heart via TAK1 and p38.

Cell Tissue Res 2015 Sep 1;361(3):779-87. Epub 2015 Mar 1.

Department of Cardiac Development and Remodelling, Max-Planck-Institute for Heart and Lung Research, Ludwigstrasse 43, D-61231, Bad Nauheim, Germany.

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http://dx.doi.org/10.1007/s00441-015-2139-2DOI Listing
September 2015
5 Reads
3.565 Impact Factor

The failing heart is a major source of circulating FGF23 via oncostatin M receptor activation.

J Heart Lung Transplant 2015 Sep 17;34(9):1211-4. Epub 2015 Jun 17.

Department of Cardiac Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.healun.2015.06.007DOI Listing
September 2015
5 Reads
6.650 Impact Factor

Myocardial healing requires Reg3β-dependent accumulation of macrophages in the ischemic heart.

Nat Med 2015 Apr 9;21(4):353-62. Epub 2015 Mar 9.

Department of Cardiac Development and Remodeling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.

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http://dx.doi.org/10.1038/nm.3816DOI Listing
April 2015
16 Reads
27.363 Impact Factor

Response to letter regarding article "Role of extracellular RNA in atherosclerotic plaque formation in mice".

Circulation 2014 Oct;130(16):e144-5

Institute of Clinical Biochemistry and Pathobiochemistry, University Hospital, Würzburg, Germany.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.012346DOI Listing
October 2014
11 Reads
14.430 Impact Factor

RBM24 is a major regulator of muscle-specific alternative splicing.

Dev Cell 2014 Oct;31(1):87-99

Department of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung Research, Ludwigstraße 43, 61231 Bad Nauheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2014.08.025DOI Listing
October 2014
18 Reads
9.710 Impact Factor

Phenotypical and ultrastructural features of Oct4-positive cells in the adult mouse lung.

J Cell Mol Med 2014 Jul 3;18(7):1321-33. Epub 2014 Jun 3.

Department of Lung Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany.

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http://dx.doi.org/10.1111/jcmm.12295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124017PMC
July 2014
7 Reads

Role of extracellular RNA in atherosclerotic plaque formation in mice.

Circulation 2014 Feb 7;129(5):598-606. Epub 2013 Nov 7.

Institute for Molecular Cardiovascular Research, RWTH University Hospital Aachen, Aachen, Germany (S.S., E.A.L.); Department of Biochemistry, Medical School, Justus-Liebig-University, Giessen, Germany (H.A.C.-F., K.T.P.); Department of Microbiology, Kazan Federal University, Kazan, Russian Federation (H.A.C.-F.); Center for Cardiovascular Research, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI (S.M., Y.B., W.A.B.); Core Lab for Molecular and Structural Biology, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany (S.K.); Institute for Cardiovascular Prevention, Ludwig-Maximilians-University, Munich, Germany (C.W.); DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (C.W., A.Z.); Rudolf Virchow Center and Institute of Clinical Biochemistry and Pathobiochemistry, University Hospital Würzburg, University of Würzburg, Würzburg, Germany (A.Z.); and Department of Vascular Surgery, Klinikum rechts der Isar, Technical University, Munich, Germany (A.Z.).

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http://circ.ahajournals.org/content/early/2013/11/07/CIRCULA
Web Search
http://circ.ahajournals.org/cgi/doi/10.1161/CIRCULATIONAHA.1
Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.113.002562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946546PMC
February 2014
4 Reads
14.430 Impact Factor

Therapeutic targeting of the oncostatin M receptor-β prevents inflammatory heart failure.

Basic Res Cardiol 2014 Jan 29;109(1):396. Epub 2013 Nov 29.

Department of Cardiac Development and Remodelling, Max-Planck-Institute for Heart and Lung Research, Ludwigstrasse 43, 61321, Bad Nauheim, Germany.

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http://dx.doi.org/10.1007/s00395-013-0396-3DOI Listing
January 2014
12 Reads
5.414 Impact Factor

Myf5-positive satellite cells contribute to Pax7-dependent long-term maintenance of adult muscle stem cells.

Cell Stem Cell 2013 Nov 8;13(5):590-601. Epub 2013 Aug 8.

Department of Cardiac Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Ludwigstraße 43, 61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.stem.2013.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082715PMC
November 2013
8 Reads

Treatment with bone morphogenetic protein 2 limits infarct size after myocardial infarction in mice.

Shock 2013 Apr;39(4):353-60

Department of Medicine III, Martin-Luther-University, Halle, Germany.

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http://dx.doi.org/10.1097/SHK.0b013e318289728aDOI Listing
April 2013
16 Reads
3.045 Impact Factor

Structural remodelling in heart failure.

Exp Clin Cardiol 2002 ;7(2-3):64-8

Max Planck Institute, Bad Nauheim;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719171PMC
August 2012
1 Read
0.760 Impact Factor

Adult rat cardiac myocytes in culture: 'Second-floor' cells and coculture experiments.

Exp Clin Cardiol 2006 ;11(3):175-82

Kerckhoff Clinic, Department of Cardiac Surgery.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276155PMC
August 2012
5 Reads
0.760 Impact Factor

Platelet-derived growth factor receptor-β-positive telocytes in skeletal muscle interstitium.

J Cell Mol Med 2012 Apr;16(4):701-7

Department of Cellular and Molecular Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

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http://dx.doi.org/10.1111/j.1582-4934.2011.01505.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822841PMC
April 2012
2 Reads

Oncostatin M is a major mediator of cardiomyocyte dedifferentiation and remodeling.

Cell Stem Cell 2011 Nov;9(5):420-32

Department of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, Bad Nauheim, 61321, Germany.

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http://dx.doi.org/10.1016/j.stem.2011.08.013DOI Listing
November 2011
7 Reads

Fibrosis in endstage human heart failure: severe changes in collagen metabolism and MMP/TIMP profiles.

Int J Cardiol 2011 Aug 23;151(1):18-33. Epub 2010 May 23.

Core Lab for Molecular and Cellular Biology, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2010.04.053DOI Listing
August 2011
7 Reads
4.040 Impact Factor

TVP1022 attenuates cardiac remodeling and kidney dysfunction in experimental volume overload-induced congestive heart failure.

Circ Heart Fail 2011 Jul 10;4(4):463-73. Epub 2011 May 10.

Department of Physiology, Rappaport Faculty of Medicine, Technion, Haifa, Israel.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.111.961037DOI Listing
July 2011
7 Reads
5.891 Impact Factor

Types of cardiomyocyte death and clinical outcomes in patients with heart failure.

Authors:
Sawa Kostin

J Am Coll Cardiol 2011 Apr;57(14):1532-4

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http://dx.doi.org/10.1016/j.jacc.2010.10.049DOI Listing
April 2011
1 Read
16.503 Impact Factor

SLC4A7 sodium bicarbonate co-transporter controls mitochondrial apoptosis in ischaemic coronary endothelial cells.

Cardiovasc Res 2011 Feb 20;89(2):392-400. Epub 2010 Oct 20.

Department of Clinical Pharmacology, Ruhr-University Bochum, Universitätsstrasse 150, D-44801 Bochum, Germany.

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http://dx.doi.org/10.1093/cvr/cvq330DOI Listing
February 2011
1 Read
5.940 Impact Factor

Tissue-engineered cardiac constructs for cardiac repair.

Ann Thorac Surg 2011 Jan;91(1):320-9

Department of Cardiac Surgery, Kerckhoff Clinic, Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.athoracsur.2010.09.080DOI Listing
January 2011
15 Reads
3.850 Impact Factor

Assessment of human MAPCs for stem cell transplantation and cardiac regeneration after myocardial infarction in SCID mice.

Exp Hematol 2010 Nov 29;38(11):1105-14. Epub 2010 Jul 29.

Department of General and Vascular Surgery, Klinikum Grosshadern, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1016/j.exphem.2010.06.013DOI Listing
November 2010
14 Reads
2.480 Impact Factor

Ischemia triggers BNP expression in the human myocardium independent from mechanical stress.

Int J Cardiol 2010 Sep 29;143(3):289-97. Epub 2009 Mar 29.

Kerckhoff Heart Center, Benekestrasse 2-8, 61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2009.03.012DOI Listing
September 2010
2 Reads
4.040 Impact Factor

Myocardial telocytes: a specific new cellular entity.

Authors:
Sawa Kostin

J Cell Mol Med 2010 Jul 5;14(7):1917-21. Epub 2010 Jul 5.

Max-Planck Institute for Heart and Lung Research (W.C. Kerckhoff Institute), Bad Nauheim, Germany.

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http://dx.doi.org/10.1111/j.1582-4934.2010.01111.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823273PMC
July 2010
1 Read

SLC4A11 prevents osmotic imbalance leading to corneal endothelial dystrophy, deafness, and polyuria.

J Biol Chem 2010 May 25;285(19):14467-74. Epub 2010 Feb 25.

Max-Planck-Institut für Herz- und Lungenforschung, Parkstrasse 1, D-61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1074/jbc.M109.094680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863209PMC
May 2010
1 Read
4.573 Impact Factor

A novel small-animal model for accelerated investigation of tissue-engineered aortic valve conduits.

Tissue Eng Part C Methods 2010 Feb;16(1):41-50

Department of Thoracic and Cardiovascular Surgery, Hannover Medical School , Hannover, Germany.

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http://dx.doi.org/10.1089/ten.TEC.2008.0595DOI Listing
February 2010
5 Reads

Abnormalities in intracellular Ca2+ regulation contribute to the pathomechanism of Tako-Tsubo cardiomyopathy.

Eur Heart J 2009 Sep 13;30(17):2155-64. Epub 2009 Jun 13.

Department of Cardiology, Kerckhoff Heart Center, D-61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehp240DOI Listing
September 2009
7 Reads
15.203 Impact Factor

Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster.

J Clin Invest 2009 Sep 17;119(9):2634-47. Epub 2009 Aug 17.

Max-Planck-Institut für Herz- und Lungenforschung, Bad Nauheim, Germany.

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http://dx.doi.org/10.1172/JCI38864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735940PMC
September 2009
4 Reads
13.215 Impact Factor

Soluble adenylyl cyclase controls mitochondria-dependent apoptosis in coronary endothelial cells.

J Biol Chem 2009 May 31;284(22):14760-8. Epub 2009 Mar 31.

Abteilung für Klinische Pharmakologie, Ruhr-Universität Bochum, D-44801 Bochum, Germany.

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http://dx.doi.org/10.1074/jbc.M900925200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685657PMC
May 2009
2 Reads
4.573 Impact Factor

Acidic preconditioning protects endothelial cells against apoptosis through p38- and Akt-dependent Bcl-xL overexpression.

Apoptosis 2009 Jan;14(1):90-6

Department of Clinical Pharmacology, Ruhr-University Bochum, Universitätsstr. 150, 44801 Bochum, Germany.

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http://dx.doi.org/10.1007/s10495-008-0287-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757620PMC
January 2009
7 Reads
3.685 Impact Factor

Efficient homing of multipotent adult mesenchymal stem cells depends on FROUNT-mediated clustering of CCR2.

Cell Stem Cell 2008 Jun;2(6):566-75

Max-Planck-Institute for Heart and Lung Research, Parkstrasse 1, 61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.stem.2008.03.003DOI Listing
June 2008
9 Reads

mRNA cargo no longer on time.

Am J Physiol Heart Circ Physiol 2008 Mar 18;294(3):H1130-2. Epub 2008 Jan 18.

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http://dx.doi.org/10.1152/ajpheart.91528.2007DOI Listing
March 2008
4 Reads
3.840 Impact Factor

Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice.

Circ Res 2008 Mar 31;102(6):703-10. Epub 2008 Jan 31.

Max-Planck-Institute for Heart and Lung Research, Department of Cardiac Development and Remodelling, Bad Nauheim, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.164558DOI Listing
March 2008
7 Reads
11.020 Impact Factor

Expression profiling of cardiac genes in Tako-Tsubo cardiomyopathy: insight into a new cardiac entity.

J Mol Cell Cardiol 2008 Feb 3;44(2):395-404. Epub 2007 Dec 3.

Kerckhoff Heart Center, Department of Cardiology, Benekestr. 2-8, D-61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2007.10.015DOI Listing
February 2008
5 Reads
4.660 Impact Factor

Zonula occludens-1 and connexin 43 expression in the failing human heart.

Authors:
Sawa Kostin

J Cell Mol Med 2007 Jul-Aug;11(4):892-5

Core Lab for Molecular and Structural Biology, W. G. Kerckhoff Institute, Max-Planck Institute for Heart and Lung Research, Parkstrasse 1, 61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1111/j.1582-4934.2007.00063.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823265PMC
November 2007
4 Reads

Importance of bicarbonate transport for ischaemia-induced apoptosis of coronary endothelial cells.

J Cell Mol Med 2007 Jul-Aug;11(4):798-809

Abteilung für Klinische Pharmakologie, Ruhr-Universität Bochum, Universitätsstrasse 150, D-44801 Bochum, Germany.

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http://dx.doi.org/10.1111/j.1582-4934.2007.00053.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823258PMC
November 2007
1 Read

Tako-Tsubo cardiomyopathy: intraindividual structural analysis in the acute phase and after functional recovery.

Eur Heart J 2007 Oct 29;28(20):2456-64. Epub 2007 Mar 29.

Department of Cardiology, Kerckhoff Heart Center, Benekestr. 2-8, D-61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehl570DOI Listing
October 2007
3 Reads
15.203 Impact Factor

Extracellular RNA mediates endothelial-cell permeability via vascular endothelial growth factor.

Blood 2007 Oct 18;110(7):2457-65. Epub 2007 Jun 18.

Department of Biochemistry Medical School, Justus-Liebig-University, Giessen, Germany.

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http://dx.doi.org/10.1182/blood-2006-08-040691DOI Listing
October 2007
5 Reads
10.452 Impact Factor

Endothelial nitric oxide synthase activity is essential for vasodilation during blood flow recovery but not for arteriogenesis.

Arterioscler Thromb Vasc Biol 2007 Sep 7;27(9):1926-33. Epub 2007 Jun 7.

Department of Cell Biology & Genetics, Erasmus University MC Rotterdam, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1161/ATVBAHA.107.145375DOI Listing
September 2007
1 Read
6.000 Impact Factor

S100A4 is upregulated in injured myocardium and promotes growth and survival of cardiac myocytes.

Cardiovasc Res 2007 Jul 6;75(1):40-50. Epub 2007 Apr 6.

The Laboratory of Molecular and Cellular Cardiology, The Danish National Research Foundation Centre for Cardiac Arrhythmia, Department of Medicine B, H:S Rigshospitalet, Copenhagen University Hospital, Denmark.

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http://dx.doi.org/10.1016/j.cardiores.2007.03.027DOI Listing
July 2007
4 Reads
5.940 Impact Factor

Cellular cardiomyoplasty: improvement of left ventricular function correlates with the release of cardioactive cytokines.

Stem Cells 2007 Jan 14;25(1):236-44. Epub 2006 Sep 14.

Department of Medicine III, Martin Luther University, Halle, Germany.

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http://dx.doi.org/10.1634/stemcells.2006-0374DOI Listing
January 2007
11 Reads
6.523 Impact Factor

Ischemic acidosis causes apoptosis in coronary endothelial cells through activation of caspase-12.

Cardiovasc Res 2007 Jan 29;73(1):172-80. Epub 2006 Sep 29.

Department of Clinical Pharmacology, Ruhr-Universität Bochum, Germany.

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http://dx.doi.org/10.1016/j.cardiores.2006.09.018DOI Listing
January 2007
2 Reads
5.940 Impact Factor

Bone marrow-derived cells contribute to infarct remodelling.

Cardiovasc Res 2006 Sep 14;71(4):661-71. Epub 2006 Jun 14.

Kerckhoff Heart Center, Benekestrasse 2-8, 61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.cardiores.2006.06.013DOI Listing
September 2006
1 Read
5.940 Impact Factor

Images in cardiovascular medicine. Natural tissue engineering inside a ventricular septum defect occluder.

Circulation 2006 Apr;113(16):e718-9

Department of Cardiology, Kerckhoff Heart Centre, 61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.105.582999DOI Listing
April 2006
3 Reads
14.430 Impact Factor

Reduced sarcoplasmic reticulum Ca2+ -ATPase activity and dephosphorylated phospholamban contribute to contractile dysfunction in human hibernating myocardium.

Mol Cell Biochem 2006 Jan;282(1-2):53-63

Department of Cardiology, Kerckhoff Heart Centre, Benekestr. 2-8, Bad Nauheim 61231, Germany.

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http://dx.doi.org/10.1007/s11010-006-1171-7DOI Listing
January 2006
1 Read
2.393 Impact Factor

Pathways of myocyte death: implications for development of clinical laboratory biomarkers.

Authors:
Sawa Kostin

Adv Clin Chem 2005 ;40:37-98

Department of Experimental Cardiology, Max-Planck Institute, Bad Nauheim, Germany.

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January 2006
1 Read
2.650 Impact Factor

Expression of cytoskeletal, linkage and extracellular proteins in failing dog myocardium.

Heart Fail Rev 2005 Dec;10(4):297-303

Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1007/s10741-005-7544-2DOI Listing
December 2005
3 Reads
3.790 Impact Factor

Carvedilol improves myocardial contractility compared with metoprolol in patients with chronic hibernating myocardium after revascularization.

J Cardiovasc Pharmacol Ther 2005 Sep;10(3):181-90

Division of Cardiology, Department of Medicine, University of Texas Medical Branch, Galveston, TX 77555-0553, USA.

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http://dx.doi.org/10.1177/107424840501000306DOI Listing
September 2005
2 Reads
3.072 Impact Factor

Transforming growth factor-beta1 downregulates beating frequency and remodeling of cultured rat adult cardiomyocytes.

Cell Tissue Res 2005 Jul 18;321(1):57-66. Epub 2005 May 18.

Research Group Vascular Genomics, Kerckhoff Clinic, Bad Nauheim, Germany.

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http://dx.doi.org/10.1007/s00441-005-1125-5DOI Listing
July 2005
5 Reads
3.565 Impact Factor

Cell death and adenosine triphosphate: the paradox.

Circulation 2005 Jul;112(1):6-8

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http://dx.doi.org/10.1161/CIRCULATIONAHA.105.551846DOI Listing
July 2005
2 Reads
14.430 Impact Factor

Downregulation of apoptosis-inducing factor in harlequin mutant mice sensitizes the myocardium to oxidative stress-related cell death and pressure overload-induced decompensation.

Circ Res 2005 Jun 2;96(12):e92-e101. Epub 2005 Jun 2.

Hubrecht Laboratory and Interuniversity Cardiology Institute Netherlands, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands.

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http://dx.doi.org/10.1161/01.RES.0000172081.30327.28DOI Listing
June 2005
7 Reads
11.020 Impact Factor

Ischemia depletes dystrophin and inhibits protein synthesis in the canine heart: mechanisms of myocardial ischemic injury.

J Mol Cell Cardiol 2005 May;38(5):723-33

Department of Experimental Cardiology, Max-Planck-Institute, Benekestr. 2, D-61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2005.02.019DOI Listing
May 2005
3 Reads
4.660 Impact Factor

Gap junctional remodeling by hypoxia in cultured neonatal rat ventricular myocytes.

Cardiovasc Res 2005 Apr;66(1):64-73

Rappaport Faculty of Medicine, Technion, Haifa, Israel.

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http://dx.doi.org/10.1016/j.cardiores.2005.01.014DOI Listing
April 2005
10 Reads
5.940 Impact Factor

Matrix metalloproteinases and their tissue inhibitors in pressure-overloaded human myocardium during heart failure progression.

J Am Coll Cardiol 2004 Oct;44(8):1609-18

Dept. of Experimental Cardiology, Max-Planck-Institute, Benekestrasse 2, D-61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.jacc.2004.07.023DOI Listing
October 2004
8 Reads
16.503 Impact Factor

Enhanced connexin-43 and alpha-sarcomeric actin expression in cultured heart myocytes exposed to triiodo-L-thyronine.

J Mol Histol 2004 Jun;35(5):463-70

Institute for Heart Research, SAS, Bratislava, Slovak Republic.

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June 2004
13 Reads
1.820 Impact Factor

Human hibernating myocardium is jeopardized by apoptotic and autophagic cell death.

J Am Coll Cardiol 2004 Jun;43(12):2191-9

Department of Cardiology, Kerckhoff Clinic, Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.jacc.2004.02.053DOI Listing
June 2004
5 Reads
16.503 Impact Factor

Connexin 43 expression and distribution in compensated and decompensated cardiac hypertrophy in patients with aortic stenosis.

Cardiovasc Res 2004 May;62(2):426-36

Department of Experimental Cardiology, Max-Planck-Institute, Benekestr. 2D-61231, Bad Nauheim, Germany.

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http://dx.doi.org/10.1016/j.cardiores.2003.12.010DOI Listing
May 2004
7 Reads
5.940 Impact Factor

Bone marrow-derived cells do not incorporate into the adult growing vasculature.

Circ Res 2004 Feb 4;94(2):230-8. Epub 2003 Dec 4.

Max-Planck-Institute for Clinical & Physiological Research, Bad Nauheim, Germany.

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http://dx.doi.org/10.1161/01.RES.0000110419.50982.1CDOI Listing
February 2004
1 Read
11.020 Impact Factor

Circulating vascular progenitor cells do not contribute to compensatory lung growth.

Circ Res 2003 Aug 24;93(4):372-9. Epub 2003 Jul 24.

Department of Internal Medicine, University Clinic Giessen, Giessen, Germany.

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http://dx.doi.org/10.1161/01.RES.0000087643.60150.C2DOI Listing
August 2003
4 Reads
11.020 Impact Factor

Time- and cell type-specific induction of platelet-derived growth factor receptor-beta during cerebral ischemia.

Brain Res Mol Brain Res 2003 May;113(1-2):44-51

Department of Experimental Cardiology, Max-Planck-Institute for Physiological and Clinical Research, D-61231 Bad Nauheim, Germany.

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May 2003
2 Reads

Myocytes die by multiple mechanisms in failing human hearts.

Circ Res 2003 Apr 20;92(7):715-24. Epub 2003 Mar 20.

Max-Planck-Institute, Department of Experimental Cardiology, Benekestr 2D-61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1161/01.RES.0000067471.95890.5CDOI Listing
April 2003
5 Reads
11.020 Impact Factor

Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms.

Circulation 2003 Feb;107(7):984-91

Kerckhoff-Clinic, Department of Thoracic and Cardiovascular Surgery, Bad Nauheim, Germany.

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February 2003
4 Reads
14.430 Impact Factor

Gap junction remodeling and altered connexin43 expression in the failing human heart.

Mol Cell Biochem 2003 Jan;242(1-2):135-44

Department of Experimental Cardiology, Max-Planck-Institute, Bad Nauheim, Germany.

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January 2003
5 Reads
2.393 Impact Factor

Remodeling of the adventitia during coronary arteriogenesis.

Am J Physiol Heart Circ Physiol 2003 Jan 29;284(1):H31-40. Epub 2002 Aug 29.

Max Planck Institute, Department of Experimental Cardiology, D-61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1152/ajpheart.00478.2002DOI Listing
January 2003
4 Reads
3.840 Impact Factor

Blood monocyte concentration is critical for enhancement of collateral artery growth.

Am J Physiol Heart Circ Physiol 2002 Dec 3;283(6):H2411-9. Epub 2002 Oct 3.

Department for Experimental Cardiology, Max Planck Institute for Physiological and Clinical Research, 61231 Bad Nauheim, Germany.

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http://dx.doi.org/10.1152/ajpheart.01098.2001DOI Listing
December 2002
7 Reads
3.840 Impact Factor

Structural determinants of atrial and ventricular conduction.

Authors:
Sawa Kostin

J Cell Mol Med 2002 Jan-Mar;6(1):108-9

Department of Experimental Cardiology, Max-Planck Institute, Bad Nauheim, Germany.

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December 2002
4 Reads

Construction of autologous human heart valves based on an acellular allograft matrix.

Circulation 2002 Sep;106(12 Suppl 1):I63-I68

Leibniz Research Laboratory for Biotechnology and Artificial Organs, Hannover, Germany.

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September 2002
8 Reads
14.430 Impact Factor

Intracellular route and transcriptional competence of polyethylenimine-DNA complexes.

J Control Release 2002 Aug;82(2-3):441-54

University of Marburg, Institut für Cytologie und Cytopathologie, Robert-Koch Strasse 5, D-35033, Marburg, Germany

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August 2002
4 Reads
7.705 Impact Factor

Structural correlate of atrial fibrillation in human patients.

Cardiovasc Res 2002 May;54(2):361-79

Department of Experimental Cardiology, Max-Planck Institute, Benekestrasse 2, D-61231 Bad Nauheim, Germany.

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May 2002
4 Reads
5.940 Impact Factor

Exogenous application of transforming growth factor beta 1 stimulates arteriogenesis in the peripheral circulation.

FASEB J 2002 Mar 30;16(3):432-4. Epub 2002 Jan 30.

Max Planck Institute for Physiological and Clinical Research, Department of Experimental Cardiology, Bad Nauheim, Germany.

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http://www.fasebj.org/content/16/3/432.full.pdf
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http://www.fasebj.org/cgi/doi/10.1096/fj.01-0563fje
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http://dx.doi.org/10.1096/fj.01-0563fjeDOI Listing
March 2002
3 Reads
5.043 Impact Factor

Top co-authors

Jutta Schaper
Jutta Schaper

Max-Planck-Institute for Heart and Lung Research

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Thomas Braun
Thomas Braun

Max Planck Institute for Heart and Lung Research

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Stefan Hein
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Thomas Kubin
Thomas Kubin

Max-Planck-Institute for Heart and Lung Research

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Manfred Richter
Manfred Richter

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Wolfgang Schaper
Wolfgang Schaper

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Holger M Nef
Holger M Nef

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Christian W Hamm
Christian W Hamm

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