Publications

Current insights in obstetric antiphospholipid syndrome.
Curr Opin Obstet Gynecol 2017 Dec;29(6):397-403
aThrombosis and Thrombophilia, Guy's and St Thomas' Hospital, London, UK bCopenhagen Lupus and Vasculitis Clinic, Center for Rheumatology and Spine Diseases, Copenhagen University Hospital, Rigshospitalet, Denmark cDepartment of Clinical and Biological Sciences, University of Turin, S. Giovanni Bosco Hospital, Center of Research of Immunopathology and Rare Diseases - Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley dDepartment of Clinical and Biological Sciences, University of Turin, S. Giovanni Bosco Hospital, Nephrology and Dialysis Unit, Turin, Italy.

Chronic kidney disease and anticoagulation: from vitamin K antagonists and heparins to direct oral anticoagulant agents.
Intern Emerg Med 2017 Dec 19;12(8):1101-1108. Epub 2017 Sep 19.
Center of Research of Immunopathology and Rare Diseases-Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, S. Giovanni Bosco Hospital, Department of Clinical and Biological Sciences, University of Turin, Piazza del Donatore di Sangue 3, 10154, Turin, Italy.

Ubiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled Trial.
Arterioscler Thromb Vasc Biol 2017 Oct 6;37(10):1923-1932. Epub 2017 Jul 6.
From the Instituto Maimónides de Investigación Biomédica de Córdoba, Córdoba, Spain (C.P.-S., M.Á.A., P.R.-L., M.C.A.-A., Y.J.-G., I.A.-d.l.R., A.R.A., P.S., E.C.-E., N.B., F.V., C.L.-P.); Unidad de Gestión Clínica Reumatología (M.Á.A., E.C.-E., C.L.-P.), Unidad de Gestión Clínica Radiología (P.S.), and Unidad de Gestión Clínica Hematología (F.V.), Hospital Universitario Reina Sofía, Córdoba, Spain; Departamento de Biología Celular, Fisiología e Inmunología, Campus de Excelencia Internacional Agroalimentario, ceiA3 (L.F.-d.R., J.A.G.-R., J.M.V.) and Departamento de Medicina (Medicina, Dermatología y Otorrinolaringología) (E.C.-E.), Universidad de Córdoba, Córdoba, Spain; Lupus Research Unit, Hospital St Thomas, London, United Kingdom (M.J.C.); and Center of Research of Immunopathology and Rare Diseases-Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, University of Turin, Italy (S.S., I.C.).


Prevalence and Thrombotic Risk Assessment of Anti-β2 Glycoprotein I Domain I Antibodies: A Systematic Review.
Semin Thromb Hemost 2017 Aug 4. Epub 2017 Aug 4.
Center of Research of Immunopathology and Rare Diseases - Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, and SCDU Nephrology and Dialysis, University of Turin and S. Giovanni Bosco Hospital, Turin, Italy.

The "4 plus 2" rituximab protocol makes maintenance treatment unneeded in patients with refractory ANCA-associated vasculitis: A 10 years observation study.
Oncotarget 2017 Aug 23;8(32):52072-52077. Epub 2017 May 23.
Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.

The challenge of treating hepatitis C virus-associated cryoglobulinemic vasculitis in the era of anti-CD20 monoclonal antibodies and direct antiviral agents.
Oncotarget 2017 Jun;8(25):41764-41777
Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, S. Giovanni Bosco Hospital and University of Turin, Turin, Italy.

Outpatient percutaneous native renal biopsy: safety profile in a large monocentric cohort.
BMJ Open 2017 Jun 21;7(6):e015243. Epub 2017 Jun 21.
Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases-Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, University of Turin, San Giovanni Hospital, Turin, Italy.

Autologous hematopoietic stem cell transplantation in Systemic Lupus Erythematosus and antiphospholipid syndrome: A systematic review.
Autoimmun Rev 2017 May 7;16(5):469-477. Epub 2017 Mar 7.
Department of Rheumatology, Dubai Hospital, Dubai, UAE; Lupus Research Unit, Guy's and St Thomas' Hospitals NHS Foundation Trust, London, UK; Lupus Research Unit, Division of Women's Health, King's College London, London, UK.

Novel diagnostic and therapeutic frontiers in thrombotic anti-phospholipid syndrome.
Intern Emerg Med 2017 Feb 2;12(1):1-7. Epub 2017 Jan 2.
Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, S. Giovanni Bosco Hospital, Piazza del Donatore di Sangue 3, 10154, Turin, Italy.

The efficacy of hydroxychloroquine in altering pregnancy outcome in women with antiphospholipid antibodies. Evidence and clinical judgment.
Thromb Haemost 2016 Jan 17;115(2):285-90. Epub 2015 Sep 17.
Prof B. J. Hunt, Thrombosis & Haemophilia Centre, St Thomas' Hospital, Westminster Bridge road, London, SE1 7EH, UK, Tel.: +44 2071882736, Fax: +44 2071882717, E-mail:

A 4-year observation in lupus nephritis patients treated with an intensified B-lymphocyte depletion without immunosuppressive maintenance treatment-Clinical response compared to literature and immunological re-assessment.
Autoimmun Rev 2015 Dec 2;14(12):1123-30. Epub 2015 Aug 2.
Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Center of Research of Immunopathology and Rare Diseases-Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, Turin, Italy.

Rivaroxaban use in patients with antiphospholipid syndrome and previous venous thromboembolism.
Blood Coagul Fibrinolysis 2015 Jun;26(4):476-7
aResearch Fellow in Thrombosis and Haemostasis, Guy's and St Thomas' Guy's & St Thomas' Hospital, London, UK bCentro di Ricerche di Immunologia Clinica ed Immunopatologia e Documentazione su Malattie Rare (CMID), Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Italy cConsultant in Thrombosis & Thrombophilia dProfessor of Thrombosis & Haemostasis, Kings Health Partners & Consultant in Thrombosis & Thrombophilia, Guy's & St Thomas' NHS Foundation Trust, London, UK.


The global anti-phospholipid syndrome score in primary APS.
Rheumatology (Oxford) 2015 Jan 13;54(1):134-8. Epub 2014 Aug 13.
Graham Hughes Lupus Research Laboratory, Lupus Research Unit, The Rayne Institute, Division of Women's Health, King's College London, London, UK, Centro di Ricerche di Immunologia Clinica ed Immunopatologia e Documentazione su Malattie Rare (CMID), Università di Torino, Turin, Italy and Louise Coote Lupus Unit, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London, UK.

Use of intravenous immunoglobulin in patients with active vasculitis associated with concomitant infection.
J Clin Rheumatol 2015 Jan;21(1):35-7
From the *Graham Hughes Lupus Research Laboratory, Lupus Research Unit, The Rayne Institute, Division of Women's Health, King's College London, London, United Kingdom; †Centro di Ricerche di Immunologia Clinica ed Immunopatologia e Documentazione su Malattie Rare, Università di Torino, Turin, Italy; and ‡Louise Coote Lupus Unit, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London, United Kingdom.


Autoantibodies involved in neuropsychiatric manifestations associated with systemic lupus erythematosus: a systematic review.
J Neurol 2014 Sep 21;261(9):1706-14. Epub 2014 Jun 21.
Graham Hughes Lupus Research Laboratory, Lupus Research Unit, Division of Women's Health, The Rayne Institute, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London, SE1 7EH, UK.

Targeted therapy in antiphospholipid syndrome.
Curr Opin Rheumatol 2014 May;26(3):269-75
aGraham Hughes Lupus Research Laboratory, Lupus Research Unit, Division of Women's Health, The Rayne Institute, King's College, London, UK bCentro di Ricerche di Immunologia Clinica ed Immunopatologia e Documentazione su Malattie Rare (CMID), Università di Torino, Italy cLouise Coote Lupus Unit, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London, UK.

Anti-prothrombin (aPT) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies and the risk of thrombosis in the antiphospholipid syndrome. A systematic review.
Thromb Haemost 2014 Feb 31;111(2):354-64. Epub 2013 Oct 31.
Dr. Maria Laura Bertolaccini, Graham Hughes Lupus Research Laboratory, Lupus Research Unit, The Rayne Institute, Division of Women's Health, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, UK, Tel.: +44 02071883569, Fax: +44 02076202658, E-mail:

Prevalence of antibodies to prothrombin in solid phase (aPT) and to phosphatidylserine-prothrombin complex (aPS/PT) in patients with and without lupus anticoagulant.
Thromb Haemost 2013 Feb 20;109(2):207-13. Epub 2012 Dec 20.
Lupus Research Unit, The Rayne Institute, Division of Women's Health, King's College London, 4th Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, UK.

8-isoprostane, prostaglandin E2, C-reactive protein and serum amyloid A as markers of inflammation and oxidative stress in antiphospholipid syndrome: a pilot study.
Inflamm Res 2012 Aug 26;61(8):809-16. Epub 2012 May 26.
Dipartimento di Malattie Rare, Immunologiche, Ematologiche ed Immunoematologiche, Ospedale Torino Nord Emergenza San G. Bosco ed Università di Torino, Turin, Italy.

Mycophenolate mofetil as steroid-sparing treatment for elderly patients with giant cell arteritis: report of three cases.
Aging Clin Exp Res 2012 Jun;24(3):273-7
Dipartimento di Malattie Rare, Immunologiche, Ematologiche ed Immunopatologiche, Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Ospedale Torino Nord, Emergenza San G. Bosco ed Università di Torino, Italy.



Long-term effects of methylprednisolone pulses and mycophenolate mofetil in IgA nephropathy patients at risk of progression.
J Nephrol 2012 Mar-Apr;25(2):198-203
Center for Immunopathology and Rare Diseases, Department of Rare, Immunologic, Haematologic and Immunohaematologic Diseases, San G. Bosco Hospital and University of Turin, Turin, Italy.

Long-term effects of rituximab added to cyclophosphamide in refractory patients with vasculitis.
Am J Nephrol 2011 8;34(2):175-80. Epub 2011 Jul 8.
Dipartimento di Malattie Rare, Immunologiche, Ematologiche ed Immunoematologiche, Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare (CMID), Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Ospedale Torino Nord Emergenza San G. Bosco ed Università di Torino, Italia. dario.roccatello @ unito.it

Improved (4 Plus 2) Rituximab Protocol for Severe Cases of Mixed Cryoglobulinemia: A 6-Year Observational Study.
Am J Nephrol 2016 29;43(4):251-60. Epub 2016 Apr 29.
Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, S. Giovanni Bosco Hospital, Turin, Italy.

Thrombotic risk assessment in antiphospholipid syndrome: the role of new antibody specificities and thrombin generation assay.
Clin Mol Allergy 2016 15;14. Epub 2016 Jul 15.
Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Hospital, University of Turin, piazza del donatore di Sangue 3, 10054 Turin, Italy.

Antiphospholipid antibodies: crossroads between autoimmunity and infections?
Intern Emerg Med 2017 06 12;12(4):557-558. Epub 2017 Apr 12.
Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases-Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, S. Giovanni Bosco Hospital, University of Turin, Piazza del Donatore di Sangue 3, 10154, Turin, Italy.

High-Dose Rituximab Ineffective for Focal Segmental Glomerulosclerosis: A Long-Term Observation Study.
Am J Nephrol 2017 13;46(2):108-113. Epub 2017 Jul 13.
Center of Research of Immunopathology and Rare Diseases - Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.

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