Saul J Karpen

Saul J Karpen

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Saul J Karpen

Saul J Karpen

Publications by authors named "Saul J Karpen"

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Organic solute transporter-β (SLC51B) deficiency in two brothers with congenital diarrhea and features of cholestasis.

Hepatology 2018 08 11;68(2):590-598. Epub 2018 May 11.

Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA.

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http://dx.doi.org/10.1002/hep.29516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847420PMC
August 2018

BILIARY ATRESIA: Clinical and Research Challenges for the 21 Century.

Hepatology 2018 Mar 31. Epub 2018 Mar 31.

Pediatric Liver Center, Children's Hospital Colorado and Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.

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http://dx.doi.org/10.1002/hep.29905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167205PMC
March 2018

Novel Bile Acid Therapies for Liver Disease.

Authors:
Saul J Karpen

Gastroenterol Hepatol (N Y) 2018 Feb;14(2):117-119

Raymond F. Schinazi Distinguished Biomedical Chair Professor of Pediatrics Division Chief, Pediatric Gastroenterology, Hepatology and Nutrition Emory University School of Medicine Children's Healthcare of Atlanta Atlanta, Georgia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866303PMC
February 2018

Level of γ-glutamyltransferase in 2-Year-old Children With Biliary Atresia Associates With Progression of Portal Hypertension.

Clin Gastroenterol Hepatol 2017 07 1;15(7):1133-1135. Epub 2017 Mar 1.

Emory University School of Medicine/Children's Healthcare of Atlanta, Atlanta, Georgia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15423565173025
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http://dx.doi.org/10.1016/j.cgh.2017.02.025DOI Listing
July 2017

New-Onset Scleral Icterus in a School-Aged Female.

Clin Pediatr (Phila) 2017 Jan 19;56(1):93-96. Epub 2016 Jul 19.

1 Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1177/0009922816650599DOI Listing
January 2017

Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives.

Hepatology 2017 01 4;65(1):350-362. Epub 2016 Aug 4.

Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/hep.28709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191969PMC
January 2017

Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

J Pediatr Gastroenterol Nutr 2017 01;64(1):154-168

*Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA †Division of Paediatric Gastroenterology and Hepatology, Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany ‡Yale New Haven Hospital Transplantation Center, Yale University School of Medicine, New Haven, CT §Department of Pediatrics, Karolinska University Hospital, CLINTEC, Karolinska Institute, Stockholm, Sweden ||Paediatric Centre for Hepatology, Gastroenterology and Nutrition King's College Hospital, London, UK ¶Section of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO #Swiss Center for Liver Disease in Children, University Hospitals Geneva, Geneva, Switzerland **Indiana University School of Medicine/Riley Hospital for Children, Indianapolis, IN ††Division of Pediatric Gastroenterology, Hepatology and Nutrition, Hasbro Children's Hospital, The Warren Alpert School of Medicine at Brown University, Providence, RI ‡‡Division of Pediatric Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, University of Toronto, Toronto, Canada §§Department of Pediatrics, Emory University School of Medicine/Children's Healthcare of Atlanta, Atlanta, GA.

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http://dx.doi.org/10.1097/MPG.0000000000001334DOI Listing
January 2017

Bile acid excess induces cardiomyopathy and metabolic dysfunctions in the heart.

Hepatology 2017 01 29;65(1):189-201. Epub 2016 Nov 29.

Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL.

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http://dx.doi.org/10.1002/hep.28890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299964PMC
January 2017

Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice.

Sci Transl Med 2016 09;8(357):357ra122

Department of Pediatrics, Emory University School of Medicine, 1760 Haygood Drive Northeast, Atlanta, GA 30322, USA. Children's Healthcare of Atlanta, 2015 Uppergate Drive Northeast, Atlanta, GA 30322, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056562PMC
http://dx.doi.org/10.1126/scitranslmed.aaf4823DOI Listing
September 2016

Inflammation-associated upregulation of the sulfated steroid transporter Slc10a6 in mouse liver and macrophage cell lines.

Hepatol Res 2016 Jul 19;46(8):794-803. Epub 2015 Nov 19.

Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1111/hepr.12609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851596PMC
July 2016

Genetic contributors and modifiers of biliary atresia.

Dig Dis 2015 27;33(3):408-14. Epub 2015 May 27.

Emory University School of Medicine, Atlanta, Ga., USA.

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http://dx.doi.org/10.1159/000371694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579603PMC
March 2016

Nuancing insulin's actions in liver through rapid NCOR1 phosphorylation.

Authors:
Saul J Karpen

Hepatology 2015 Nov 29;62(5):1344-5. Epub 2015 Aug 29.

Division of Pediatric Gastroenterology, Hepatology and Nutrition, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA.

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http://dx.doi.org/10.1002/hep.28014DOI Listing
November 2015

Intestinal transport and metabolism of bile acids.

J Lipid Res 2015 Jun 10;56(6):1085-99. Epub 2014 Sep 10.

Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Emory University, Atlanta, GA 30322.

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http://dx.doi.org/10.1194/jlr.R054114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442867PMC
June 2015

Saturated fat and cholesterol are critical to inducing murine metabolic syndrome with robust nonalcoholic steatohepatitis.

J Nutr Biochem 2015 Mar 6;26(3):285-92. Epub 2014 Dec 6.

Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2014.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727836PMC
March 2015

Not all (bile acids) who wander are lost: the first report of a patient with an isolated NTCP defect.

Hepatology 2015 Jan 20;61(1):24-7. Epub 2014 Nov 20.

Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA.

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http://dx.doi.org/10.1002/hep.27294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280297PMC
January 2015

P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy.

Am J Physiol Gastrointest Liver Physiol 2014 Dec 9;307(11):G1073-87. Epub 2014 Oct 9.

Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Texas Children's Liver Center, Houston, Texas; Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas;

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http://ajpgi.physiology.org/content/ajpgi/307/11/G1073.full.
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http://ajpgi.physiology.org/content/ajpgi/early/2014/10/06/a
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http://ajpgi.physiology.org/cgi/doi/10.1152/ajpgi.00092.2014
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http://dx.doi.org/10.1152/ajpgi.00092.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254960PMC
December 2014

Total serum bilirubin predicts fat-soluble vitamin deficiency better than serum bile acids in infants with biliary atresia.

J Pediatr Gastroenterol Nutr 2014 Dec;59(6):702-7

*Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA †Department of Surgery and Department of Biostatistics, University of Michigan, Ann Arbor, MI ‡Department of Pediatrics, Washington University, St Louis, MO §Department of Pediatrics, Mount Sinai Medical Center, New York, NY ||Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH ¶Department of Pediatrics, Texas Children's Hospital, Houston #Department of Pediatrics, Children's Health Care of Atlanta, Atlanta, GA **Department of Gastroenterology, Children's Hospital Los Angeles, Los Angeles, CA ††Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA ‡‡Department of Pediatrics, Riley Children's Hospital, Indianapolis, IN §§Department of Pediatrics, Seattle Children's Hospital, Seattle, WA ||||Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada ¶¶School of Public Health, University of Michigan, Ann Arbor ##Department of Pediatrics, University of California San Francisco, San Francisco ***Department of Pediatrics, Johns Hopkins University, Baltimore †††National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD ‡‡‡Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora §§§Department of Pediatrics, Saint Louis University School of Medicine, St Louis, MO ||||||Department of Pediatric Surgery, Children's Hospital Los Angeles, Los Angeles, CA ¶¶¶Department of Pediatrics, Children's Memorial Hospital, Chicago, IL.

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http://dx.doi.org/10.1097/MPG.0000000000000547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243585PMC
December 2014

Sexually dimorphic genome-wide binding of retinoid X receptor alpha (RXRα) determines male-female differences in the expression of hepatic lipid processing genes in mice.

PLoS One 2013 19;8(8):e71538. Epub 2013 Aug 19.

Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071538PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747242PMC
April 2014

Bile acids reach out to the spinal cord: new insights to the pathogenesis of itch and analgesia in cholestatic liver disease.

Hepatology 2014 Apr 14;59(4):1638-41. Epub 2014 Feb 14.

Department of Internal Medicine, Section on Gastroenterology, Wake Forest School of Medicine, Winston Salem, NC.

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http://doi.wiley.com/10.1002/hep.26786
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http://dx.doi.org/10.1002/hep.26786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966955PMC
April 2014

Impaired bile acid handling and aggravated liver injury in mice expressing a hepatocyte-specific RXRα variant lacking the DNA-binding domain.

J Hepatol 2014 Feb 10;60(2):362-9. Epub 2013 Oct 10.

Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2013.09.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946967PMC
February 2014

Discordant presentation of biliary atresia in premature monozygotic twins.

J Pediatr Gastroenterol Nutr 2013 Oct;57(4):e22-3

*Division of Pediatric Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine †Department of Pathology and Immunology, Texas Children's Hospital, Houston, TX ‡Department of Pediatrics/Liver Center, Emory University, Atlanta, GA.

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http://dx.doi.org/10.1097/MPG.0b013e31826a1044DOI Listing
October 2013

Phytosterols promote liver injury and Kupffer cell activation in parenteral nutrition-associated liver disease.

Sci Transl Med 2013 Oct;5(206):206ra137

Section of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1126/scitranslmed.3006898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070735PMC
October 2013

Do therapeutic bile acids hit the sweet spot of glucose metabolism in NAFLD?

Authors:
Saul J Karpen

Gastroenterology 2013 Sep 25;145(3):508-10. Epub 2013 Jul 25.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085130106
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http://dx.doi.org/10.1053/j.gastro.2013.07.017DOI Listing
September 2013

Liver transplantation in cystic fibrosis: a report from Baylor College of Medicine and the Texas Children's Hospital.

Pediatr Transplant 2013 May 15;17(3):271-7. Epub 2013 Mar 15.

Michael E. DeBakey Department of Surgery, Baylor College Of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1111/petr.12057DOI Listing
May 2013

Curiouser and curiouser!

Authors:
Saul J Karpen

J Hepatol 2012 Aug 23;57(2):237-8. Epub 2012 May 23.

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http://linkinghub.elsevier.com/retrieve/pii/S016882781200357
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http://dx.doi.org/10.1016/j.jhep.2012.05.006DOI Listing
August 2012

Progressive familial intrahepatic cholestasis type 3: overlapping presentation with Wilson disease.

Clin Pediatr (Phila) 2012 Jul 4;51(7):689-91. Epub 2012 Jun 4.

Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1177/0009922812451076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678905PMC
July 2012

Patients with biliary atresia have elevated direct/conjugated bilirubin levels shortly after birth.

Pediatrics 2011 Dec 21;128(6):e1428-33. Epub 2011 Nov 21.

Department of Pediatrics, BaylorCollege of Medicine, Houston,TX, USA.

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http://dx.doi.org/10.1542/peds.2011-1869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387898PMC
December 2011

Cardiac structural and functional alterations in infants and children with biliary atresia, listed for liver transplantation.

Gastroenterology 2011 Oct 14;141(4):1264-72, 1272.e1-4. Epub 2011 Jul 14.

Section of Pediatric Critical Care, Department of Pathology, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1053/j.gastro.2011.06.082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740524PMC
October 2011

Language and motor skills are impaired in infants with biliary atresia before transplantation.

J Pediatr 2010 Jun 10;156(6):936-940.e1. Epub 2010 Mar 10.

Texas Children's Liver Center, Texas Children's Hospital and Department of Pediatrics, Baylor College of Medicine, Houston, TX; Unité de Gastroentérologie pédiatrique, Hôpital des Enfants, Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.jpeds.2009.12.014DOI Listing
June 2010

Pediatric liver transplantation for primary malignant liver tumors with a focus on hepatic epithelioid hemangioendothelioma: the UNOS experience.

Pediatr Transplant 2010 May 30;14(3):326-31. Epub 2009 Dec 30.

Michael E. DeBakey Department of Surgery, Division of Abdominal Transplantation and Hepatobiliary Surgery, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1111/j.1399-3046.2009.01266.xDOI Listing
May 2010

The role of inflammation in cholestasis: clinical and basic aspects.

Semin Liver Dis 2010 May 26;30(2):186-94. Epub 2010 Apr 26.

Texas Children's Liver Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1055/s-0030-1253227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746018PMC
May 2010

Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.

Gut 2010 Apr;59(4):521-30

Laboratory of Experimental and Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University Graz, Graz, Austria.

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http://dx.doi.org/10.1136/gut.2009.186528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756478PMC
April 2010

The new therapeutic frontier--nuclear receptors and the liver.

J Hepatol 2010 Mar 24;52(3):455-62. Epub 2009 Dec 24.

Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Texas Children's Liver Center, Baylor College of Medicine, Pediatrics/Liver Center, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.jhep.2009.12.002DOI Listing
March 2010

Pattern of diagnostic evaluation for the causes of pediatric acute liver failure: an opportunity for quality improvement.

J Pediatr 2009 Dec 29;155(6):801-806.e1. Epub 2009 Jul 29.

Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado Denver School of Medicine and the Pediatric Liver Center, The Children's Hospital, Aurora, CO, USA.

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http://dx.doi.org/10.1016/j.jpeds.2009.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035352PMC
December 2009

Redundant roles for cJun-N-terminal kinase 1 and 2 in interleukin-1beta-mediated reduction and modification of murine hepatic nuclear retinoid X receptor alpha.

J Hepatol 2009 Nov 20;51(5):898-908. Epub 2009 Aug 20.

Texas Children's Liver Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.jhep.2009.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818213PMC
November 2009

Recommendations for screening, monitoring, and referral of pediatric chronic hepatitis B.

Pediatrics 2009 Nov 5;124(5):e1007-13. Epub 2009 Oct 5.

Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1542/peds.2009-0567DOI Listing
November 2009

Treatment of neonatal hemochromatosis with exchange transfusion and intravenous immunoglobulin.

J Pediatr 2009 Oct 28;155(4):566-71. Epub 2009 Jun 28.

Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00223476090037
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http://dx.doi.org/10.1016/j.jpeds.2009.04.012DOI Listing
October 2009

Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis.

Front Biosci (Landmark Ed) 2009 Jan 1;14:2599-630. Epub 2009 Jan 1.

Department of Pediatrics Center for Liver, Digestive and Metabolic Diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085779PMC
http://dx.doi.org/10.2741/3400DOI Listing
January 2009

Liver tumors: pediatric population.

Liver Transpl 2008 Nov;14(11):1545-56

Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1002/lt.21654DOI Listing
November 2008

Failure of P-selectin blockade alone to protect the liver from ischemia-reperfusion injury in the isolated blood-perfused rat liver.

World J Gastroenterol 2008 Nov;14(44):6808-16

Department of Surgery, Liver Transplant Center Laboratory, Baylor College of Medicine, Houston, TX 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773875PMC
http://dx.doi.org/10.3748/wjg.14.6808DOI Listing
November 2008

Improving the lives of adults with liver disease by focusing on children.

Authors:
Saul J Karpen

Hepatology 2008 Aug;48(2):353-4

Department of Pediatrics/Gastroenterology, Texas Children's Liver Center, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/hep.22407DOI Listing
August 2008

Liver ischemia and ischemia-reperfusion induces and trafficks the multi-specific metal transporter Atp7b to bile duct canaliculi: possible preferential transport of iron into bile.

Biol Trace Elem Res 2008 Apr 7;122(1):26-41. Epub 2007 Nov 7.

Michael E. DeBakey Department of Surgery, Liver Transplant Center Laboratory, Baylor College of Medicine, Houston, TX 77030, USA.

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http://link.springer.com/10.1007/s12011-007-8057-8
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http://dx.doi.org/10.1007/s12011-007-8057-8DOI Listing
April 2008

Regulation of hepatic drug-metabolizing enzyme genes by Toll-like receptor 4 signaling is independent of Toll-interleukin 1 receptor domain-containing adaptor protein.

Drug Metab Dispos 2008 Jan 11;36(1):95-101. Epub 2007 Oct 11.

College of Pharmacy, University of Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1124/dmd.107.018051DOI Listing
January 2008

Stigmasterol, a soy lipid-derived phytosterol, is an antagonist of the bile acid nuclear receptor FXR.

Pediatr Res 2007 Sep;62(3):301-6

Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Texas Children's Liver Center, Baylor College of Medicine, Houston 77030, USA.

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http://dx.doi.org/10.1203/PDR.0b013e3181256492DOI Listing
September 2007

Intestinal failure-associated liver disease: management and treatment strategies past, present, and future.

Semin Liver Dis 2007 Aug;27(3):251-8

Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-2007-985070
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http://dx.doi.org/10.1055/s-2007-985070DOI Listing
August 2007

Isolated orthotopic liver transplantation for parenteral nutrition-associated liver injury.

JPEN J Parenter Enteral Nutr 2006 Nov-Dec;30(6):526-9

Michael E. DeBakey Department of Surgery, Section of Gastroenterology, Hepatology and Nutrition, Texas Children's Liver Center, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1177/0148607106030006526DOI Listing
January 2007

Rosiglitazone attenuates suppression of RXRalpha-dependent gene expression in inflamed liver.

J Hepatol 2007 Jan 23;46(1):115-23. Epub 2006 Oct 23.

Texas Children's Liver Center/Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.jhep.2006.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847570PMC
January 2007

Evaluation and management of patients with propionic acidemia undergoing liver transplantation: a comprehensive review.

Pediatr Transplant 2006 Nov;10(7):773-81

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1111/j.1399-3046.2006.00569.xDOI Listing
November 2006

The natural history of hepatitis C virus in pediatric liver transplant recipients.

Liver Transpl 2006 Jul;12(7):1119-23

Michael E. DeBakey Department of Surgery, Hepatology and Nutrition, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.

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http://doi.wiley.com/10.1002/lt.20793
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http://dx.doi.org/10.1002/lt.20793DOI Listing
July 2006

Impact of pretransplant growth retardation in pediatric liver transplantation.

J Pediatr Gastroenterol Nutr 2006 Jul;43(1):89-94

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston TX 77030, USA.

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http://dx.doi.org/10.1097/01.mpg.0000226378.03247.1fDOI Listing
July 2006

Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: roles for JNK and SER260.

J Biol Chem 2006 Jun 21;281(22):15434-40. Epub 2006 Mar 21.

Texas Children's Liver Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M508277200
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http://dx.doi.org/10.1074/jbc.M508277200DOI Listing
June 2006

The pediatric end-stage liver disease (PELD) model as a predictor of survival benefit and posttransplant survival in pediatric liver transplant recipients.

Liver Transpl 2006 Mar;12(3):475-80

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/lt.20703DOI Listing
March 2006

Risk stratification of adult patients undergoing orthotopic liver transplantation for fulminant hepatic failure.

Transplantation 2006 Jan;81(2):195-201

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1097/01.tp.0000188149.90975.63DOI Listing
January 2006

Treatment of acute tacrolimus whole-blood elevation with phenobarbital in the pediatric liver transplant recipient.

Pediatr Transplant 2005 Dec;9(6):792-6

Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1111/j.1399-3046.2005.00368.xDOI Listing
December 2005

Combined lung and liver transplantation: the United States experience.

Transplantation 2005 Nov;80(9):1161-7

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1097/01.tp.0000165717.23652.09DOI Listing
November 2005

Orthotopic liver transplantation for biliary atresia: the U.S. experience.

Liver Transpl 2005 Oct;11(10):1193-200

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/lt.20509DOI Listing
October 2005

Adult liver transplant candidate attitudes toward graft sharing are not obstacles to split liver transplantation.

Am J Transplant 2005 Aug;5(8):2047-51

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1111/j.1600-6143.2005.00946.xDOI Listing
August 2005

Exercising the nuclear option to treat cholestasis: CAR and PXR ligands.

Authors:
Saul J Karpen

Hepatology 2005 Aug;42(2):266-9

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http://dx.doi.org/10.1002/hep.20833DOI Listing
August 2005

Neonatal hemochromatosis: radiographical and histological signs.

Liver Transpl 2005 Aug;11(8):998-1000

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/lt.20461DOI Listing
August 2005

Intrahepatic cholestasis: summary of an American Association for the Study of Liver Diseases single-topic conference.

Hepatology 2005 Jul;42(1):222-35

Cincinnati Children's Hospital Medical Center and the University of Cincinnati, OH, USA.

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http://dx.doi.org/10.1002/hep.20729DOI Listing
July 2005

Liver transplantation for severe hepatic graft-versus-host disease: an analysis of aggregate survival data.

Liver Transpl 2005 May;11(5):525-31

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/lt.20389DOI Listing
May 2005

Kupffer cell depletion with liposomal clodronate prevents suppression of Ntcp expression in endotoxin-treated rats.

J Hepatol 2005 Jan;42(1):102-9

Department of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases, University of Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jhep.2004.09.019DOI Listing
January 2005

Mechanisms underlying lack of insulin-like growth factor-binding protein-3 expression in non-small-cell lung cancer.

Oncogene 2004 Aug;23(39):6569-80

Department of Thoracic Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Box 432, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/sj.onc.1207882DOI Listing
August 2004

Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation.

Nucl Recept 2004 Aug 16;2(1). Epub 2004 Aug 16.

Texas Children's Liver Center, Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.1186/1478-1336-2-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514570PMC
August 2004

Calcium is good for the nucleus.

J Hepatol 2004 Apr;40(4):720-2

Texas Children's Liver Center, Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.jhep.2004.02.012DOI Listing
April 2004

Asymptomatic small bowel intussusception associated with post-transplant lymphoproliferative disease.

Pediatr Transplant 2004 Apr;8(2):196-7

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1111/j.1399-3046.2004.00168.xDOI Listing
April 2004

Extracellular ATP activates c-jun N-terminal kinase signaling and cell cycle progression in hepatocytes.

Hepatology 2004 Feb;39(2):393-402

Department of Pediatrics, Section of Gastroenterology, Hepatology and Nutrition, Texas Children's Liver Center, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/hep.20075DOI Listing
February 2004

Itchin' for a diversion.

Gastroenterology 2003 Apr;124(4):1155-7

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http://dx.doi.org/10.1016/s0016-5085(03)70072-9DOI Listing
April 2003

Down-regulation of the Na+/taurocholate cotransporting polypeptide during pregnancy in the rat.

J Hepatol 2003 Feb;38(2):148-55

Department of Gastroenterology, Pontificia Universidad Católica de Chile, School of Medicine, Marcoleta # 367, Santiago 6510260, Chile.

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http://dx.doi.org/10.1016/s0168-8278(02)00379-3DOI Listing
February 2003