Publications by authors named "Saskia le Cessie"

100Publications

Meta-analysis of continuous outcomes: Using pseudo IPD created from aggregate data to adjust for baseline imbalance and assess treatment-by-baseline modification.

Res Synth Methods 2020 Jul 8. Epub 2020 Jul 8.

Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/jrsm.1434DOI Listing
July 2020

Authors' reply: Who is afraid of non-normal data? Choosing between t-tests and non-parametric tests.

Eur J Endocrinol 2020 08;183(2):L5-L6

Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1530/EJE-20-0596DOI Listing
August 2020

The role of C-reactive protein, adiponectin and leptin in the association between abdominal adiposity and insulin resistance in middle-aged individuals.

Nutr Metab Cardiovasc Dis 2020 Jul 5;30(8):1306-1314. Epub 2020 May 5.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.numecd.2020.04.021DOI Listing
July 2020

Prediction meets causal inference: the role of treatment in clinical prediction models.

Eur J Epidemiol 2020 Jul 22;35(7):619-630. Epub 2020 May 22.

Department of Biomedical Data Sciences, Leiden University Medical Center, Zone S5-P, PO Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10654-020-00636-1DOI Listing
July 2020

Mortality after Delay of Adequate Empiric Antimicrobial Treatment of Bloodstream Infection.

J Clin Med 2020 May 7;9(5). Epub 2020 May 7.

Department of Infectious Diseases, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.

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http://dx.doi.org/10.3390/jcm9051378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290963PMC
May 2020

Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis.

Hum Reprod Update 2020 May 2. Epub 2020 May 2.

Department of Gynaecology and Obstetrics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands.

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http://dx.doi.org/10.1093/humupd/dmaa010DOI Listing
May 2020

The joint effect of genetic risk factors and different types of combined oral contraceptives on venous thrombosis risk.

Br J Haematol 2020 Apr 27. Epub 2020 Apr 27.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/bjh.16666DOI Listing
April 2020

Hidden analyses: a review of reporting practice and recommendations for more transparent reporting of initial data analyses.

BMC Med Res Methodol 2020 03 13;20(1):61. Epub 2020 Mar 13.

Department of Mathematics, Faculty of Mathematics, Natural Sciences and Information Technology, University of Primorksa, Koper, Slovenia.

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http://dx.doi.org/10.1186/s12874-020-00942-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071755PMC
March 2020

The effect of treatment delay on time-to-recovery in the presence of unobserved heterogeneity.

Biom J 2020 Jul 20;62(4):1012-1024. Epub 2020 Jan 20.

Department of Biomedical Data Sciences, Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/bimj.201900131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383985PMC
July 2020

Who is afraid of non-normal data? Choosing between parametric and non-parametric tests.

Eur J Endocrinol 2020 Feb;182(2):E1-E3

Departments of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1530/EJE-19-0922DOI Listing
February 2020

Ageing, age-related diseases and oxidative stress: What to do next?

Ageing Res Rev 2020 01 13;57:100982. Epub 2019 Nov 13.

Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2019.100982DOI Listing
January 2020

Metabolomics: a search for biomarkers of visceral fat and liver fat content.

Metabolomics 2019 10 5;15(10):139. Epub 2019 Oct 5.

Department of Clinical Epidemiology, Leiden University Medical Center, Postal Zone C7-P, PO Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s11306-019-1599-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778586PMC
October 2019

The Association between Adult Weight Gain and Insulin Resistance at Middle Age: Mediation by Visceral Fat and Liver Fat.

J Clin Med 2019 Sep 28;8(10). Epub 2019 Sep 28.

Department of Clinical Epidemiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.

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http://dx.doi.org/10.3390/jcm8101559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832997PMC
September 2019

The association between overall and abdominal adiposity and depressive mood: A cross-sectional analysis in 6459 participants.

Psychoneuroendocrinology 2019 12 4;110:104429. Epub 2019 Sep 4.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1016/j.psyneuen.2019.104429DOI Listing
December 2019

Determinants of transfusion decisions in the ICU: haemoglobin concentration, what else? - a retrospective cohort study.

Vox Sang 2019 Nov 8;114(8):816-825. Epub 2019 Sep 8.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/vox.12831DOI Listing
November 2019

Authors' Reply: A comparison of different methods to handle missing data in the context of propensity score analysis.

Eur J Epidemiol 2020 01 27;35(1):89-91. Epub 2019 Aug 27.

Department of Clinical Epidemiology and Department of Biomedical Data Sciences, Leiden University Medical Center, Albinusdreef 2, C7-P, 2333 ZA, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10654-019-00553-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058597PMC
January 2020

Survival Bias in Mendelian Randomization Studies: A Threat to Causal Inference.

Epidemiology 2019 11;30(6):813-816

Department of Clinical Epidemiology, LUMC, Leiden, The Netherlands.

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http://dx.doi.org/10.1097/EDE.0000000000001072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784762PMC
November 2019

Individualized Thromboprophylaxis in Patients with Lower-Leg Cast Immobilization-A Validation and Subgroup Analysis in the POT-CAST Trial.

Thromb Haemost 2019 Sep 28;119(9):1508-1516. Epub 2019 Jul 28.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1055/s-0039-1693410DOI Listing
September 2019

Risk prediction of recurrent venous thrombosis; where are we now and what can we add?

J Thromb Haemost 2019 09 4;17(9):1527-1534. Epub 2019 Jul 4.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jth.14535
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http://dx.doi.org/10.1111/jth.14535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851549PMC
September 2019

Comparing Methods for Measurement Error Detection in Serial 24-h Hormonal Data.

J Biol Rhythms 2019 08 12;34(4):347-363. Epub 2019 Jun 12.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1177/0748730419850917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637814PMC
August 2019

Regarding "Variable selection - A review and recommendations for the practicing statistician" by G. Heinze, C. Wallisch, and D. Dunkler.

Biom J 2019 11 6;61(6):1595-1597. Epub 2019 May 6.

Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1002/bimj.201900088DOI Listing
November 2019

Different statistical techniques dealing with confounding in observational research: measuring the effect of breast-conserving therapy and mastectomy on survival.

J Cancer Res Clin Oncol 2019 Jun 24;145(6):1485-1493. Epub 2019 Apr 24.

Department of Research, Netherlands Comprehensive Cancer Organisation, P.O. Box 19079, 3501 DB, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00432-019-02919-xDOI Listing
June 2019

Post-thrombotic syndrome: Short and long-term incidence and risk factors.

Thromb Res 2019 May 6;177:102-109. Epub 2019 Mar 6.

Department of Thrombosis and Hemostasis, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, the Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00493848193015
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http://dx.doi.org/10.1016/j.thromres.2019.03.003DOI Listing
May 2019

One-stage random effects meta-analysis using linear mixed models for aggregate continuous outcome data.

Res Synth Methods 2019 Sep 8;10(3):360-375. Epub 2019 Jan 8.

Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands.

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http://dx.doi.org/10.1002/jrsm.1331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767371PMC
September 2019

Risk of Clinically Relevant Pericardial Effusion After Pediatric Cardiac Surgery.

Pediatr Cardiol 2019 Mar 11;40(3):585-594. Epub 2018 Dec 11.

Division of Pediatric Cardiology, Department of Pediatrics, Leiden University Medical Center, PO Box 9600, 2300RC, Leiden, The Netherlands.

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http://link.springer.com/10.1007/s00246-018-2031-4
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http://dx.doi.org/10.1007/s00246-018-2031-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420454PMC
March 2019

Estimating the Effect of Treatment Duration Using Observational Data in Practice.

Epidemiology 2019 03;30(2):e7-e8

Section Medical Statistics, Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, the Netherlands, Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, the Netherlands Section Medical Statistics, Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, the Netherlands.

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http://dx.doi.org/10.1097/EDE.0000000000000943DOI Listing
March 2019

A comparison of different methods to handle missing data in the context of propensity score analysis.

Eur J Epidemiol 2019 Jan 19;34(1):23-36. Epub 2018 Oct 19.

Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, C7-P, 2333 ZA, Leiden, The Netherlands.

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http://link.springer.com/10.1007/s10654-018-0447-z
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http://dx.doi.org/10.1007/s10654-018-0447-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325992PMC
January 2019

Venous Thrombosis Risk after Arthroscopy of the Knee: Derivation and Validation of the L-TRiP(ascopy) Score.

Thromb Haemost 2018 Oct 20;118(10):1823-1831. Epub 2018 Sep 20.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1055/s-0038-1670660DOI Listing
October 2018

NUMBER: standardized reference intervals in the Netherlands using a 'big data' approach.

Clin Chem Lab Med 2018 12;57(1):42-56

Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, TheNetherlands.

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http://dx.doi.org/10.1515/cclm-2018-0462DOI Listing
December 2018

Combining multiple imputation and bootstrap in the analysis of cost-effectiveness trial data.

Stat Med 2019 01 12;38(2):210-220. Epub 2018 Sep 12.

Department of Medical Decision Making & Quality of Care, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/sim.7956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585698PMC
January 2019

Effects of age and genetic variations in VKORC1, CYP2C9 and CYP3A4 on the phenprocoumon dose in pediatric patients.

Pharmacogenomics 2018 10 12;19(15):1195-1202. Epub 2018 Sep 12.

Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.2217/pgs-2018-0095DOI Listing
October 2018

Increased cardiovascular disease risk in women with a history of recurrent miscarriage.

Acta Obstet Gynecol Scand 2018 Oct 17;97(10):1192-1199. Epub 2018 Jun 17.

Department of Obstetrics Birth Center Wilhelmina's Children Hospital, Division Women and Baby, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1111/aogs.13392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175487PMC
October 2018

Visit-to-visit lipid variability: Clinical significance, effects of lipid-lowering treatment, and (pharmaco) genetics.

J Clin Lipidol 2018 Mar - Apr;12(2):266-276.e3. Epub 2018 Jan 11.

Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Section of Gerontology and Geriatrics, Department of Internal Medicine, LUMC, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.jacl.2018.01.001DOI Listing
September 2019

Associations of Abdominal Subcutaneous and Visceral Fat with Insulin Resistance and Secretion Differ Between Men and Women: The Netherlands Epidemiology of Obesity Study.

Metab Syndr Relat Disord 2018 02 17;16(1):54-63. Epub 2018 Jan 17.

1 Department of Clinical Epidemiology, Leiden University Medical Center , Leiden, the Netherlands .

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http://dx.doi.org/10.1089/met.2017.0128DOI Listing
February 2018

External Validation of Three Prediction Tools for Patients at Risk of a Complicated Course of Clostridium difficile Infection: Disappointing in an Outbreak Setting.

Infect Control Hosp Epidemiol 2017 08 8;38(8):897-905. Epub 2017 Jun 8.

2Department of Medical Microbiology and Infection Control,VU Medical Center,Amsterdam,The Netherlands.

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http://dx.doi.org/10.1017/ice.2017.89DOI Listing
August 2017

Is Hepatic Triglyceride Content Associated with Aortic Pulse Wave Velocity and Carotid Intima-Media Thickness? The Netherlands Epidemiology of Obesity Study.

Radiology 2017 10 29;285(1):73-82. Epub 2017 May 29.

From the Departments of Radiology (R.L.W., J.J.M.W., A.d.R., H.J.L.), Clinical Epidemiology (R.d.M., K.B.G., M.d.H., S.l.C., F.R.R.), Internal Medicine (K.B.G.), Medical Statistics and Bio-informatics (S.l.C.), Endocrinology (R.L.W., J.W.A.S.), and Cardiology (J.W.J.), Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, the Netherlands; Department of Internal Medicine, VU University Medical Center, Amsterdam, the Netherlands (M.d.H.); and Department of Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands (J.W.A.S.).

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http://dx.doi.org/10.1148/radiol.2017160916DOI Listing
October 2017

Statin use and risk of recurrent venous thrombosis: results from the MEGA follow-up study.

Res Pract Thromb Haemost 2017 Jul 25;1(1):112-119. Epub 2017 May 25.

Department of Clinical Epidemiology Leiden University Medical Center Leiden the Netherlands.

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http://dx.doi.org/10.1002/rth2.12003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058203PMC
July 2017

Transplant as a competing risk in the analysis of dialysis patients.

Nephrol Dial Transplant 2017 Apr;32(suppl_2):ii53-ii59

Department of Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfx012DOI Listing
April 2017

Antibiotic use as a marker of acute infection and risk of first and recurrent venous thrombosis.

Br J Haematol 2017 03 17;176(6):961-970. Epub 2017 Feb 17.

Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/bjh.14551DOI Listing
March 2017

High prevalence of autoimmune disease in the rare inflammatory bone disorder sternocostoclavicular hyperostosis: survey of a Dutch cohort.

Orphanet J Rare Dis 2017 01 25;12(1):20. Epub 2017 Jan 25.

Department of Medicine, Division of Endocrinology & Centre for Bone Quality, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333ZA, The Netherlands.

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http://dx.doi.org/10.1186/s13023-017-0573-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267408PMC
January 2017

Reference curves for the Australian/Canadian Hand Osteoarthritis Index in the middle-aged Dutch population.

Rheumatology (Oxford) 2017 05;56(5):745-752

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/kew483DOI Listing
May 2017

Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting.

N Engl J Med 2017 02 3;376(6):515-525. Epub 2016 Dec 3.

From the Departments of Clinical Epidemiology (R.A.A., B.N., A.A., S.C., F.R.R., S.C.C.), Orthopedic Surgery (R.A.A., B.N., R.G.H.H.N.), Medical Statistics and Bioinformatics (S.C.), Trauma Surgery (I.B.S.), and Thrombosis and Hemostasis (S.C.C.), Leiden University Medical Center, Leiden, and Julius Center for Health Sciences and Patient Care, University Medical Center Utrecht, Utrecht (A.A.) - both in the Netherlands.

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http://dx.doi.org/10.1056/NEJMoa1613303DOI Listing
February 2017

Higher Visit-to-Visit Low-Density Lipoprotein Cholesterol Variability Is Associated With Lower Cognitive Performance, Lower Cerebral Blood Flow, and Greater White Matter Hyperintensity Load in Older Subjects.

Circulation 2016 Jul;134(3):212-21

From Department of Cardiology (R.A.J.S., S.T., J.W.J.), Section of Gerontology and Geriatrics, Department of Internal Medicine (R.A.J.S., S.T., B.S., A.J.M.d.C.), Department of Radiology (B.S., J.v.d.G., M.A.v.B.), Department of Clinical Epidemiology (S.l.C.), Department of Medical Statistics and Bioinformatics (S.l.C.), and Einthoven Laboratory for Experimental Vascular Medicine (J.W.J.), Leiden University Medical Center, Leiden, The Netherlands; and Interuniversity Cardiology Institute Netherlands, Utrecht, The Netherlands (J.W.J.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020627DOI Listing
July 2016

Association between Hepatic Triglyceride Content and Left Ventricular Diastolic Function in a Population-based Cohort: The Netherlands Epidemiology of Obesity Study.

Radiology 2016 May 26;279(2):443-50. Epub 2016 Jan 26.

From the Departments of Radiology (R.L.W., A.d.R., H.J.L.), Endocrinology (R.L.W., J.W.A.S.), Clinical Epidemiology (R.d.M., M.d.H., S.l.C., F.R.R.), Medical Statistics and Bio-informatics (S.l.C.), Thrombosis and Haemostasis (F.R.R.), and Cardiology (J.W.J.), Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, the Netherlands.

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http://dx.doi.org/10.1148/radiol.2015150035DOI Listing
May 2016

Instrumental variable analysis as a complementary analysis in studies of adverse effects: venous thromboembolism and second-generation versus third-generation oral contraceptives.

Pharmacoepidemiol Drug Saf 2016 Mar 8;25(3):317-24. Epub 2016 Jan 8.

Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/pds.3956DOI Listing
March 2016

Physician's Prescribing Preference as an Instrumental Variable: Exploring Assumptions Using Survey Data.

Epidemiology 2016 Mar;27(2):276-83

From the aDepartment of Clinical Epidemiology, bDepartment of Medical Statistics and Bioinformatics, cDepartment of Endocrinology and Metabolic Diseases, Leiden University Medical Centre, Leiden, The Netherlands; dDepartment of Clinical Epidemiology, Aarhus Medical Centre, Aarhus, Denmark; eBern Institute of General Practice, University of Bern, Bern, Switzerland; fDepartment of Epidemiology and Public Health, University College Cork, Cork, Ireland; gDepartment of General Practice and Primary Health Care, University of Auckland, Auckland, New Zealand; hArthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire, United Kingdom; iInstitute for Evidence-based Medicine in Old age (IEMO), Leiden, The Netherlands; jDepartment of Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, The Netherlands; kInstitute of General Practice, Johann Wolfgang Goethe University, Frankfurt, Germany; lDepartment of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland; mInstitute of General Practice and Health Services Research, University of Zürich, Zürich, Switzerland; nDepartment of Primary and Community Care, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands; oDepartment of Internal Medicine, University Hospital of Zürich, Zürich, Switzerland; pDepartment of Public Health and Primary Care, Leiden University Medical Centre, Leiden, The Netherlands; and qResearch department of Primary Care and Population health, University College London, United Kingdom.

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http://dx.doi.org/10.1097/EDE.0000000000000425DOI Listing
March 2016

A systematic approach to initial data analysis is good research practice.

J Thorac Cardiovasc Surg 2016 Jan 28;151(1):25-7. Epub 2015 Sep 28.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.jtcvs.2015.09.085DOI Listing
January 2016

Bias Formulas for Estimating Direct and Indirect Effects When Unmeasured Confounding Is Present.

Authors:
Saskia le Cessie

Epidemiology 2016 Jan;27(1):125-32

From the Department of Clinical Epidemiology and Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/EDE.0000000000000407DOI Listing
January 2016

Type 2 diabetes is associated with postprandial amino acid measures.

Arch Biochem Biophys 2016 Jan 10;589:138-44. Epub 2015 Aug 10.

Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.abb.2015.08.003DOI Listing
January 2016

Comparison of dosing algorithms for acenocoumarol and phenprocoumon using clinical factors with the standard care in the Netherlands.

Thromb Res 2015 Jul 2;136(1):94-100. Epub 2015 May 2.

Department of Pharmaceutical Sciences, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2015.04.034DOI Listing
July 2015

Mendelian randomization studies: a review of the approaches used and the quality of reporting.

Int J Epidemiol 2015 Apr 6;44(2):496-511. Epub 2015 May 6.

Department of Clinical Epidemiology, Department of Endocrinology and Metabolic Diseases, and Department of Medical Statistics and Bioinformatics, Leiden University Medical Centre, Leiden, The Netherlands. Department of Clinical Epidemiology, Department of Endocrinology and Metabolic Diseases, and Department of Medical Statistics and Bioinformatics, Leiden University Medical Centre, Leiden, The Netherlands.

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http://ije.oxfordjournals.org/content/44/2/496.full.pdf
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http://www.ije.oxfordjournals.org/cgi/doi/10.1093/ije/dyv071
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http://dx.doi.org/10.1093/ije/dyv071DOI Listing
April 2015

Mendelian randomization studies in the elderly.

Epidemiology 2015 Mar;26(2):e15-6

Department of Clinical Epidemiology Leiden University Medical Centre The Netherlands

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http://dx.doi.org/10.1097/EDE.0000000000000243DOI Listing
March 2015

Reproducibility of exhaled nitric oxide measurements in overweight and obese adults.

BMC Res Notes 2014 Nov 3;7:775. Epub 2014 Nov 3.

Department of Pulmonology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, the Netherlands.

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http://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0
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http://dx.doi.org/10.1186/1756-0500-7-775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237750PMC
November 2014

Effect of providing free glasses on children's educational outcomes in China: cluster randomized controlled trial.

BMJ 2014 Sep 23;349:g5740. Epub 2014 Sep 23.

Key Laboratory of Ophthalmology and Division of Preventive Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China ORBIS International, New York, NY, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172821PMC
http://dx.doi.org/10.1136/bmj.g5740DOI Listing
September 2014

The association between dialysis modality and the risk for dialysis technique and non-dialysis technique-related infections.

Nephrol Dial Transplant 2014 Dec 28;29(12):2244-50. Epub 2014 Aug 28.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfu285DOI Listing
December 2014

Sample size importantly limits the usefulness of instrumental variable methods, depending on instrument strength and level of confounding.

J Clin Epidemiol 2014 Nov 12;67(11):1258-64. Epub 2014 Aug 12.

Department of Clinical Epidemiology, C7-P, Leiden University Medical Centre, PO Box 9600, 2300 RC Leiden, The Netherlands; Department of Medical Statistics and Bioinformatics, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.jclinepi.2014.05.019DOI Listing
November 2014

Commentary: regression discontinuity design: let's give it a try to evaluate medical and public health interventions.

Epidemiology 2014 Sep;25(5):738-41

From Departments of aClinical Epidemiology, bDepartment of Medical Statistics and Bioinformatics, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1097/EDE.0000000000000145DOI Listing
September 2014

STRengthening analytical thinking for observational studies: the STRATOS initiative.

Stat Med 2014 Dec 30;33(30):5413-32. Epub 2014 Jul 30.

Center for Medical Biometry and Medical Informatics, Medical Center - University of Freiburg.

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http://doi.wiley.com/10.1002/sim.6265
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http://dx.doi.org/10.1002/sim.6265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320765PMC
December 2014

Physician's preference-based instrumental variable analysis: is it valid and useful in a moderate-sized study?

Epidemiology 2014 Nov;25(6):923-7

From the aDepartment of Clinical Epidemiology; bDepartment of Intensive Care; cDepartment of Medical Statistics and Bioinformatics; and dDepartment of Endocrinology and Metabolic Diseases, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1097/EDE.0000000000000151DOI Listing
November 2014

The increased risk of venous thromboembolism by advancing age cannot be attributed to the higher incidence of cancer in the elderly: the Tromsø study.

Eur J Epidemiol 2014 Apr 19;29(4):277-84. Epub 2014 Apr 19.

Hematological Research Group, Department of Clinical Medicine, University of Tromsø, 9037, Tromsø, Norway,

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http://dx.doi.org/10.1007/s10654-014-9902-7DOI Listing
April 2014

Immunosuppressants and alloimmunization against red blood cell transfusions.

Transfusion 2014 Aug 1;54(8):1981-7. Epub 2014 Apr 1.

Center for Clinical Transfusion Research, Sanquin Research, Leiden, the Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/trf.12639DOI Listing
August 2014

Predicting the severity of joint damage in rheumatoid arthritis; the contribution of genetic factors.

Ann Rheum Dis 2015 May 15;74(5):876-82. Epub 2014 Jan 15.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2013-204277DOI Listing
May 2015

Sex difference in risk of second but not of first venous thrombosis: paradox explained.

Circulation 2014 Jan 21;129(1):51-6. Epub 2013 Oct 21.

Department of Clinical Epidemiology (R.E.J.R., W.M.L., F.R.R., S.C.C., S.l.C.), Einthoven Laboratory for Experimental Vascular Medicine (W.M.L., F.R.R., S.C.C.), Thrombosis and Hemostasis Research Center (F.R.R.), and Department of Medical Statistics and Bioinformatics (S.l.C.), Leiden University Medical Center, Leiden, The Netherlands.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.113.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.004768DOI Listing
January 2014

Differences in circumferential resection margin involvement after abdominoperineal excision and low anterior resection no longer significant.

Ann Surg 2014 Jun;259(6):1150-5

*Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands †Department of Surgery, Catharina Hospital, Eindhoven, The Netherlands ‡Departments of Clinical Epidemiology and Medical Statistics and Bioinformatics, Leiden University Medical Centre, Leiden, The Netherlands §Department of Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands ¶Department of Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.

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http://dx.doi.org/10.1097/SLA.0000000000000225DOI Listing
June 2014