Publications by authors named "Saskia M Wilting"

44Publications

Identification of Deregulated Pathways, Key Regulators, and Novel miRNA-mRNA Interactions in HPV-Mediated Transformation.

Cancers (Basel) 2020 Mar 16;12(3). Epub 2020 Mar 16.

Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.

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http://dx.doi.org/10.3390/cancers12030700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140059PMC
March 2020

miR-9-5p Exerts a Dual Role in Cervical Cancer and Targets Transcription Factor TWIST1.

Cells 2019 Dec 26;9(1). Epub 2019 Dec 26.

Cancer Center Amsterdam, Pathology, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.3390/cells9010065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017350PMC
December 2019

A tale on rabbit ears and pan-handles, the rings that rule all.

EBioMedicine 2019 Nov 29;49:17-18. Epub 2019 Oct 29.

Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.10.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945197PMC
November 2019

A two-gene methylation signature for the diagnosis of bladder cancer in urine.

Epigenomics 2019 02 1;11(3):337-347. Epub 2019 Feb 1.

Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, Amsterdam, The Netherlands.

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https://www.futuremedicine.com/doi/10.2217/epi-2018-0094
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http://dx.doi.org/10.2217/epi-2018-0094DOI Listing
February 2019

Ridge estimation of network models from time-course omics data.

Biom J 2019 03 22;61(2):391-405. Epub 2018 Aug 22.

Department of Epidemiology and Biostatistics, Amsterdam School of Public Health, VU University Medical Center, MB, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/bimj.201700195
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http://dx.doi.org/10.1002/bimj.201700195DOI Listing
March 2019

Molecular heterogeneity in human papillomavirus-dependent and -independent vulvar carcinogenesis.

Cancer Med 2018 09 20;7(9):4542-4553. Epub 2018 Jul 20.

Cancer Center Amsterdam, Department of Pathology, VU University Medical Center, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/cam4.1633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144162PMC
September 2018

Improved high-dimensional prediction with Random Forests by the use of co-data.

BMC Bioinformatics 2017 12 28;18(1):584. Epub 2017 Dec 28.

Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, 1007 MB, The Netherlands.

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http://dx.doi.org/10.1186/s12859-017-1993-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745983PMC
December 2017

Molecular events leading to HPV-induced high grade neoplasia.

Papillomavirus Res 2016 12 12;2:85-88. Epub 2016 Apr 12.

Department of Pathology, VU University Medical Center Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.pvr.2016.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886901PMC
December 2016

A Strategy to Find Suitable Reference Genes for miRNA Quantitative PCR Analysis and Its Application to Cervical Specimens.

J Mol Diagn 2017 09;19(5):625-637

Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15251578173006
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http://dx.doi.org/10.1016/j.jmoldx.2017.04.010DOI Listing
September 2017

Better diagnostic signatures from RNAseq data through use of auxiliary co-data.

Bioinformatics 2017 May;33(10):1572-1574

Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/bioinformatics/btw837DOI Listing
May 2017

Ridge estimation of the VAR(1) model and its time series chain graph from multivariate time-course omics data.

Biom J 2017 Jan 7;59(1):172-191. Epub 2016 Nov 7.

Department of Epidemiology and Biostatistics, VU University Medical Center, 1007, MB, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/bimj.201500269
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http://dx.doi.org/10.1002/bimj.201500269DOI Listing
January 2017

Better prediction by use of co-data: adaptive group-regularized ridge regression.

Stat Med 2016 Feb 13;35(3):368-81. Epub 2015 Sep 13.

Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/sim.6732DOI Listing
February 2016

Longitudinal assessment of DNA methylation changes during HPVE6E7-induced immortalization of primary keratinocytes.

Epigenetics 2015 23;10(1):73-81. Epub 2015 Jan 23.

a Department of Pathology; Unit of Molecular Pathology ; VU University Medical Center ; Amsterdam , The Netherlands.

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http://dx.doi.org/10.4161/15592294.2014.990787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622457PMC
June 2016

tigaR: integrative significance analysis of temporal differential gene expression induced by genomic abnormalities.

BMC Bioinformatics 2014 Oct 2;15:327. Epub 2014 Oct 2.

Department of Epidemiology and Biostatistics, VU University Medical Center, P,O, Box 7057, 1007 MB, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/1471-2105-15-327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288633PMC
October 2014

Modeling the DNA copy number aberration patterns in observational high-throughput cancer data.

Stat Appl Genet Mol Biol 2013 Apr 19;12(2):143-74. Epub 2013 Apr 19.

Department of Epidemiology and Biostatistics, VU University Medical Center, P.O. Box 7057, MB 1007, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1515/sagmb-2012-0020DOI Listing
April 2013

Methylation-mediated transcriptional repression of microRNAs during cervical carcinogenesis.

Epigenetics 2013 Feb 16;8(2):220-8. Epub 2013 Jan 16.

Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.4161/epi.23605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592908PMC
February 2013

Focal aberrations indicate EYA2 and hsa-miR-375 as oncogene and tumor suppressor in cervical carcinogenesis.

Genes Chromosomes Cancer 2013 Jan 14;52(1):56-68. Epub 2012 Sep 14.

Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/gcc.22006
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http://dx.doi.org/10.1002/gcc.22006DOI Listing
January 2013

HPV type-related chromosomal profiles in high-grade cervical intraepithelial neoplasia.

BMC Cancer 2012 Jan 24;12:36. Epub 2012 Jan 24.

Department of Pathology, Unit of Molecular Pathology, VU University Medical Center, PO box 7057, 1007 MB Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/1471-2407-12-36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305644PMC
January 2012

Repression of MAL tumour suppressor activity by promoter methylation during cervical carcinogenesis.

J Pathol 2009 Nov;219(3):327-36

Department of Pathology, Unit of Molecular Pathology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/path.2598DOI Listing
November 2009

Chromosomal signatures of a subset of high-grade premalignant cervical lesions closely resemble invasive carcinomas.

Cancer Res 2009 Jan;69(2):647-55

Departments of Pathology and Mathematics, VU University Medical Center, Amsterdam, the Netherlands, and Department of Obstetrics and Gynaecology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2478DOI Listing
January 2009

DNA copy number gains at loci of growth factors and their receptors in salivary gland adenoid cystic carcinoma.

Clin Cancer Res 2007 Jun;13(11):3133-9

Department of Oral and Maxillofacial Surgery/Oral Pathology, Academic Centre for Dentistry Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2555DOI Listing
June 2007

CGHcall: calling aberrations for array CGH tumor profiles.

Bioinformatics 2007 Apr 31;23(7):892-4. Epub 2007 Jan 31.

Department of Pathology, VU University Medical Center, PO Box 7057, 1007MB Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/bioinformatics/btm030DOI Listing
April 2007

HPV-mediated transformation of the anogenital tract.

J Clin Virol 2005 Mar;32 Suppl 1:S25-33

Department of Pathology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jcv.2004.11.019DOI Listing
March 2005