Sascha Sauer

Sascha Sauer

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Sascha Sauer

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R-spondin-3 induces secretory, antimicrobial Lgr5 cells in the stomach.

Nat Cell Biol 2019 Jul 24;21(7):812-823. Epub 2019 Jun 24.

Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.1038/s41556-019-0339-9DOI Listing
July 2019

Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined.

Eur J Immunol 2019 May 7;49(5):790-800. Epub 2019 Mar 7.

Department of Biomedicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1002/eji.201847955DOI Listing
May 2019

Signals trigger state-specific transcriptional programs to support diversity and homeostasis in immune cells.

Sci Signal 2019 May 14;12(581). Epub 2019 May 14.

Laboratory of Functional Genomics, Nutrigenomics and Systems Biology, Scientific Genomics Platforms, Max Delbrück Center for Molecular Medicine (BIMSB/BIH), 13092 Berlin, Germany.

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http://dx.doi.org/10.1126/scisignal.aao5820DOI Listing
May 2019

The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer.

Cell Rep 2019 Jan;26(2):415-428.e5

Cancer Research Program, Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Society, 13125 Berlin, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183200
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http://dx.doi.org/10.1016/j.celrep.2018.12.059DOI Listing
January 2019

A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding.

Nat Commun 2018 12 21;9(1):5440. Epub 2018 Dec 21.

Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), 28049, Madrid, Spain.

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http://dx.doi.org/10.1038/s41467-018-07772-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303335PMC
December 2018

The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.

Immunity 2018 10;49(4):615-626.e6

Sanford-Burnham-Prebys Medical Discovery Institute, Orlando, Florida, USA; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE "Lendulet" Immunogenomics Research Group, University of Debrecen, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197058PMC
October 2018

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.

Mol Cell Endocrinol 2018 08 31;471:63-74. Epub 2017 Jul 31.

Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Hungarian Academy of Sciences, "Lendület" Immunogenomics Research Group, University of Debrecen, Debrecen, Hungary; Sanford-Burnham-Prebys Medical Discovery Institute, Orlando, FL, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03037207173041
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http://dx.doi.org/10.1016/j.mce.2017.07.034DOI Listing
August 2018

RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification.

Mol Cell Endocrinol 2018 08 2;471:51-62. Epub 2017 Aug 2.

Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL, USA; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE "Lendulet" Immunogenomics Research Group, University of Debrecen, Debrecen, Hungary. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03037207173041
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http://dx.doi.org/10.1016/j.mce.2017.07.033DOI Listing
August 2018

Perturbation-response genes reveal signaling footprints in cancer gene expression.

Nat Commun 2018 01 2;9(1):20. Epub 2018 Jan 2.

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, CB10 1SD, UK.

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http://dx.doi.org/10.1038/s41467-017-02391-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750219PMC
January 2018

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages.

Immunity 2018 01;48(1):75-90.e6

Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Sanford-Burnham-Prebys Medical Discovery Institute, 6400 Sanger Road, Orlando, FL 32827, USA; MTA-DE "Lendület" Immunogenomics Research Group, University of Debrecen, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772169PMC
January 2018

RNA-Seq Based Transcriptome Analysis of the Type I Interferon Host Response upon Vaccinia Virus Infection of Mouse Cells.

J Immunol Res 2017 9;2017:5157626. Epub 2017 Feb 9.

Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 28049 Madrid, Spain.

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http://dx.doi.org/10.1155/2017/5157626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322442PMC
March 2017

Health-beneficial nutraceuticals-myth or reality?

Appl Microbiol Biotechnol 2017 Feb 9;101(3):951-961. Epub 2017 Jan 9.

Laboratory of Functional Genomics, Nutrigenomics and Systems Biology, BIMSB and BIH Scientific Genomics Platforms, Max-Delbrück Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125, Berlin, Germany.

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http://dx.doi.org/10.1007/s00253-016-8068-5DOI Listing
February 2017

Data of oxygen- and pH-dependent oxidation of resveratrol.

Data Brief 2016 Dec 15;9:433-437. Epub 2016 Sep 15.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany; University of Würzburg, CU Systems Medicine, Josef-Schneider-Straße 2, Building D15, 97080 Würzburg, Germany; Laboratory of Functional Genomics, Nutrigenomics and Systems Biology, BIMSB and BIH Genomics Platforms, Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany.

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http://dx.doi.org/10.1016/j.dib.2016.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037118PMC
December 2016

Generating Sample-Specific Databases for Mass Spectrometry-Based Proteomic Analysis by Using RNA Sequencing.

Methods Mol Biol 2016 ;1394:219-232

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195, Berlin, Germany.

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http://dx.doi.org/10.1007/978-1-4939-3341-9_16DOI Listing
October 2016

Efficient Application of De Novo RNA Assemblers for Proteomics Informed by Transcriptomics.

J Proteome Res 2016 10 30;15(10):3938-3943. Epub 2016 Aug 30.

Otto-Warburg-Laboratory, Max Planck Institute for Molecular Genetics , Ihnestraße 63-73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1021/acs.jproteome.6b00301DOI Listing
October 2016

Hormetic shifting of redox environment by pro-oxidative resveratrol protects cells against stress.

Free Radic Biol Med 2016 10 8;99:608-622. Epub 2016 Aug 8.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany; CU Systems Medicine, University of Würzburg, Josef-Schneider-Straße 2, Building D15, 97080 Würzburg, Germany; Laboratory of Functional Genomics, Nutrigenomics and Systems Biology, BIMSB and BIH Genomics Platforms, Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.08.006DOI Listing
October 2016

OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation.

Mol Cell 2016 08 4;63(4):647-661. Epub 2016 Aug 4.

Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827, USA; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary; MTA-DE "Lendulet" Immunogenomics Research Group, University of Debrecen, 4032 Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.06.039DOI Listing
August 2016

Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA.

Nucleic Acids Res 2016 Apr 17;44(6):2538-53. Epub 2015 Nov 17.

Department of Cardiovascular Genetics, Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany Group of Cardiovascular Genetics, Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany DZHK (German Center for Cardiovascular Research), partner site Berlin, Berlin, Germany

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkv1244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824069PMC
April 2016

Serial interactome capture of the human cell nucleus.

Nat Commun 2016 Apr 4;7:11212. Epub 2016 Apr 4.

Max Planck Institute for Molecular Genetics, Otto Warburg Laboratories, 14195 Berlin, Germany.

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http://dx.doi.org/10.1038/ncomms11212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822031PMC
April 2016

Identification of novel genetic causes of Rett syndrome-like phenotypes.

J Med Genet 2016 Mar 6;53(3):190-9. Epub 2016 Jan 6.

Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal.

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http://dx.doi.org/10.1136/jmedgenet-2015-103568DOI Listing
March 2016

Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease patients reveals changes in genes associated with T cell receptor signaling.

J Autoimmun 2016 Feb 12;67:46-56. Epub 2015 Oct 12.

Molecular Pathology, Institute of Biomedical and Translational Medicine, Tartu, Estonia. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2015.09.006DOI Listing
February 2016

Erratum to 'Ligands for the Nuclear Peroxisome Proliferator-Activated Receptor Gamma': [Trends in Pharmacological Sciences 36 (2015) 688-704].

Authors:
Sascha Sauer

Trends Pharmacol Sci 2016 02 13;37(2):167. Epub 2016 Jan 13.

Otto-Warburg Laboratory, Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany; University of Würzburg, CU Systems Medicine, Josef-Schneider-Straße 2, Building D15, 97070 Wuerzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2015.12.002DOI Listing
February 2016

GORAB Missense Mutations Disrupt RAB6 and ARF5 Binding and Golgi Targeting.

J Invest Dermatol 2015 Oct 22;135(10):2368-2376. Epub 2015 May 22.

Institut fuer Medizinische Genetik und Humangenetik, Charité-Universitaetsmedizin Berlin, Berlin, Germany; Max-Planck-Institut fuer Molekulare Genetik, FG Development & Disease, Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité-Universitaetsmedizin Berlin, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.192DOI Listing
October 2015

Ligands for the Nuclear Peroxisome Proliferator-Activated Receptor Gamma.

Authors:
Sascha Sauer

Trends Pharmacol Sci 2015 Oct;36(10):688-704

Otto-Warburg Laboratory, Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany; University of Würzburg, CU Systems Medicine, Josef-Schneider-Straße 2, Building D15, 97070 Wuerzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2015.06.010DOI Listing
October 2015

Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties.

J Nat Prod 2015 May 4;78(5):1160-4. Epub 2015 May 4.

†Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1021/np500747yDOI Listing
May 2015

Nutriproteomics: facts, concepts, and perspectives.

Proteomics 2015 Mar 6;15(5-6):997-1013. Epub 2015 Feb 6.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1002/pmic.201400383DOI Listing
March 2015

A common building block for the syntheses of amorfrutin and cajaninstilbene acid libraries toward efficient binding with peroxisome proliferator-activated receptors.

Org Lett 2015 Jan 23;17(2):194-7. Epub 2014 Dec 23.

Department of Chemistry, Indian Institute of Technology Madras , Chennai 600036, India.

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http://dx.doi.org/10.1021/ol503135uDOI Listing
January 2015

PHOXTRACK-a tool for interpreting comprehensive datasets of post-translational modifications of proteins.

Bioinformatics 2014 Dec 24;30(23):3410-1. Epub 2014 Aug 24.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btu572DOI Listing
December 2014

Efficient application of next-generation sequencing for the diagnosis of rare genetic syndromes.

J Clin Pathol 2014 Dec 30;67(12):1099-103. Epub 2014 Sep 30.

Biochemistry and Molecular Genetics Department, Hospital Clínic and IDIBAPS, Barcelona, Spain Centre for Biomedical Research on Rare Diseases (CIBERER), ISCIII, Barcelona, Spain.

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http://dx.doi.org/10.1136/jclinpath-2014-202537DOI Listing
December 2014

Integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs.

J Proteome Res 2014 Dec 28;13(12):5592-602. Epub 2014 Oct 28.

Max Planck Institute for Molecular Genetics , Ihnestraße 63-73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1021/pr5005828DOI Listing
December 2014

Transcriptomics assisted proteomic analysis of Nicotiana occidentalis infected by Candidatus Phytoplasma mali strain AT.

Proteomics 2014 Aug 28;14(16):1882-9. Epub 2014 Jul 28.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1002/pmic.201300551DOI Listing
August 2014

Antidiabetic effects of chamomile flowers extract in obese mice through transcriptional stimulation of nutrient sensors of the peroxisome proliferator-activated receptor (PPAR) family.

PLoS One 2013 12;8(11):e80335. Epub 2013 Nov 12.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Berlin, Germany ; Department of Biology, Chemistry, and Pharmacy, Free University of Berlin, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080335PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827197PMC
July 2014

Amorfrutins: A promising class of natural products that are beneficial to health.

Authors:
Sascha Sauer

Chembiochem 2014 Jun 4;15(9):1231-8. Epub 2014 Jun 4.

Otto-Warburg Laboratory, Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin http://www.molgen.mpg.de/nutrigenomics.

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http://dx.doi.org/10.1002/cbic.201402124DOI Listing
June 2014

Lemon balm extract causes potent antihyperglycemic and antihyperlipidemic effects in insulin-resistant obese mice.

Mol Nutr Food Res 2014 Apr 24;58(4):903-7. Epub 2013 Nov 24.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Berlin, Germany; Department of Biology, Chemistry, and Pharmacy, Free University of Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/mnfr.201300477DOI Listing
April 2014

Comprehensive proteomic data sets for studying adipocyte-macrophage cell-cell communication.

Proteomics 2013 Dec;13(23-24):3424-8

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Berlin, Germany

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http://dx.doi.org/10.1002/pmic.201300271DOI Listing
December 2013

Diagnostic proteomics: will this impact the clinic?

Authors:
Sascha Sauer

Proteomics Clin Appl 2013 Dec;7(11-12):725-6

Otto Warburg Laboratory, MPI for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1002/prca.201370063DOI Listing
December 2013

Foam cell specific LXRα ligand.

PLoS One 2013 25;8(2):e57311. Epub 2013 Feb 25.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057311PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581588PMC
September 2013

Protein set analyses: how could this impact the clinic?

Expert Rev Proteomics 2013 Aug;10(4):305-7

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http://dx.doi.org/10.1586/14789450.2013.814883DOI Listing
August 2013

Protein sets define disease states and predict in vivo effects of drug treatment.

Mol Cell Proteomics 2013 Jul 11;12(7):1965-79. Epub 2013 Apr 11.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1074/mcp.M112.025031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708179PMC
July 2013

Discovery and characterization of protein-modifying natural products by MALDI mass spectrometry reveal potent SIRT1 and p300 inhibitors.

Angew Chem Int Ed Engl 2013 May 8;52(19):5171-4. Epub 2013 Apr 8.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1002/anie.201207325DOI Listing
May 2013

A Y2H-seq approach defines the human protein methyltransferase interactome.

Nat Methods 2013 Apr 3;10(4):339-42. Epub 2013 Mar 3.

Otto-Warburg Laboratory, Max Planck Institute for Molecular Genetics (MPIMG), Berlin, Germany.

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http://dx.doi.org/10.1038/nmeth.2397DOI Listing
April 2013

Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ.

J Med Chem 2013 Feb 6;56(4):1535-43. Epub 2013 Feb 6.

Department of Molecular Structural Biology, Helmholtz Centre for Infection Research, 38214 Braunschweig, Germany.

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http://dx.doi.org/10.1021/jm3013272DOI Listing
February 2013

The essence on mass spectrometry based microbial diagnostics.

Curr Opin Microbiol 2012 Jun 10;15(3):397-402. Epub 2012 Mar 10.

Max Planck Institute for Molecular Genetics, Otto-Warburg Laboratory, Ihnestrasse 63-73, D-14195 Berlin, Germany.

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http://dx.doi.org/10.1016/j.mib.2012.02.006DOI Listing
June 2012

Targeted enrichment of genomic DNA regions for next-generation sequencing.

Brief Funct Genomics 2011 Nov 26;10(6):374-86. Epub 2011 Nov 26.

Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1093/bfgp/elr033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245553PMC
November 2011

Familiality and molecular genetics of attention networks in ADHD.

Am J Med Genet B Neuropsychiatr Genet 2010 Jan;153B(1):148-58

Child Neuropsychology Section, Department of Child and Adolescent Psychiatry of RTWH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1002/ajmg.b.30967DOI Listing
January 2010

Mass spectrometry tools for the classification and identification of bacteria.

Nat Rev Microbiol 2010 Jan;8(1):74-82

Max Planck Institute for Molecular Genetics, Otto-Warburg Laboratory, Ihnestrasse 63-73, D-14195 Berlin, Germany.

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http://dx.doi.org/10.1038/nrmicro2243DOI Listing
January 2010

DNA polymorphisms and haplotype patterns of transcription factors involved in barley endosperm development are associated with key agronomic traits.

BMC Plant Biol 2010 Jan 8;10. Epub 2010 Jan 8.

Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK), Corrensstr, 3, 06466 Gatersleben, Germany.

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http://dx.doi.org/10.1186/1471-2229-10-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822787PMC
January 2010

Phylogenetic classification and identification of bacteria by mass spectrometry.

Nat Protoc 2009 ;4(5):732-42

Max Planck Institute for Molecular Genetics, Otto-Warburg-Laboratory, Berlin, Germany.

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http://www.nature.com/articles/nprot.2009.37
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http://dx.doi.org/10.1038/nprot.2009.37DOI Listing
June 2009

Association mapping reveals gene action and interactions in the determination of flowering time in barley.

Theor Appl Genet 2009 Jan 2;118(2):259-73. Epub 2008 Oct 2.

Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Gatersleben, Germany.

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http://dx.doi.org/10.1007/s00122-008-0896-yDOI Listing
January 2009

Single-nucleotide polymorphisms: analysis by mass spectrometry.

Nat Protoc 2006 ;1(4):1761-71

Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, Ihnestrasse 63-73, 14195 Berlin-Dahlem, Germany.

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http://dx.doi.org/10.1038/nprot.2006.257DOI Listing
October 2007

The essence of DNA sample preparation for MALDI mass spectrometry.

Authors:
Sascha Sauer

J Biochem Biophys Methods 2007 Mar 21;70(2):311-8. Epub 2006 Oct 21.

Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, Ihnestrasse 73, D-14195 Berlin, Germany.

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http://dx.doi.org/10.1016/j.jbbm.2006.10.007DOI Listing
March 2007

Matrix-assisted laser desorption/ionization mass spectrometric analysis of DNA on microarrays.

Clin Chem 2006 Jul 25;52(7):1303-10. Epub 2006 May 25.

Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, Ihnestrasse 63-73, 14195 Berlin-Dahlem, Germany.

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http://dx.doi.org/10.1373/clinchem.2006.067264DOI Listing
July 2006

Typing of single nucleotide polymorphisms by MALDI mass spectrometry: principles and diagnostic applications.

Authors:
Sascha Sauer

Clin Chim Acta 2006 Jan 31;363(1-2):95-105. Epub 2005 Aug 31.

Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics (Prof. H. Lehrach), Berlin, Germany.

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http://dx.doi.org/10.1016/j.cccn.2005.05.040DOI Listing
January 2006

Genome projects and the functional-genomic era.

Comb Chem High Throughput Screen 2005 Dec;8(8):659-67

Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, Ihnestrasse 73, D-14195 Berlin, Germany.

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December 2005

Miniaturization in functional genomics and proteomics.

Nat Rev Genet 2005 Jun;6(6):465-76

Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, Ihnestrasse 73, D-14195 Berlin, Germany.

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http://www.nature.com/articles/nrg1618
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http://dx.doi.org/10.1038/nrg1618DOI Listing
June 2005

Multiplexed hybridizations of positively charge-tagged peptide nucleic acids detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Rapid Commun Mass Spectrom 2004 ;18(16):1821-9

Max-Planck-Institute for Molecular Genetics, Department Lehrach, Ihnestrasse 73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1002/rcm.1554DOI Listing
October 2004

Automated solid-phase extraction for purification of single nucleotide polymorphism genotyping products prior to matrix-assisted laser desorption/ionisation time-of-flight mass spectrometric analysis.

J Chromatogr A 2004 Sep;1049(1-2):9-16

Department Lehrach, Max-Planck-Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin-Dahlem, Germany.

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September 2004

Extension of the GOOD assay for genotyping single nucleotide polymorphisms by matrix-assisted laser desorption/ionization mass spectrometry.

Rapid Commun Mass Spectrom 2003 ;17(12):1265-72

Max-Planck-Institute for Molecular Genetics, Abteilung Lehrach, Ihnestrasse 73, 14195 Berlin-Dahlem, Germany.

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http://doi.wiley.com/10.1002/rcm.1050
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http://dx.doi.org/10.1002/rcm.1050DOI Listing
August 2003

MALDI mass spectrometry analysis of single nucleotide polymorphisms by photocleavage and charge-tagging.

Nucleic Acids Res 2003 Jun;31(11):e63

Max-Planck-Institute for Molecular Genetics, Abteilung Lehrach, Ihnestrasse 73, 14195 Berlin-Dahlem, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC156740PMC
http://dx.doi.org/10.1093/nar/gng062DOI Listing
June 2003

Genotyping single-nucleotide polymorphisms by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2002 Dec;782(1-2):73-87

Max-Planck-Institut für Molekulare Genetik, Abteilung Lehrach, Ihnestrasse 73, 14195 Berlin-Dahlem, Germany.

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December 2002

Facile method for automated genotyping of single nucleotide polymorphisms by mass spectrometry.

Nucleic Acids Res 2002 Mar;30(5):e22

Freie Universität Berlin, Fachbereich Biologie, Chemie, Pharmazie, Takustrasse 3, 14195 Berlin-Dahlem, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC101258PMC
http://dx.doi.org/10.1093/nar/30.5.e22DOI Listing
March 2002