Publications by authors named "Sasan Zandi"

27Publications

The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization.

Cell Stem Cell 2020 Nov 17. Epub 2020 Nov 17.

Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada. Electronic address:

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November 2020

Resolution of celiac disease, IgA deficiency and platelet refractoriness after allogeneic bone marrow transplantation for acute leukemia.

Haematologica 2019 03 17;104(3):e121-e123. Epub 2019 Jan 17.

University Health Network (UHN), Laboratory Medicine Program (LMP), Department of Laboratory Hematology (Blood Transfusion Laboratory [BTL])

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March 2019

Aging, clonal hematopoiesis and preleukemia: not just bad luck?

Int J Hematol 2015 Nov 6;102(5):513-22. Epub 2015 Oct 6.

Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network (UHN), 610 University Ave, Toronto, ON, M5G 2M9, Canada.

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November 2015

CDK6 levels regulate quiescence exit in human hematopoietic stem cells.

Cell Stem Cell 2015 Mar 19;16(3):302-13. Epub 2015 Feb 19.

Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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March 2015

The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment.

Nat Immunol 2013 Jul 26;14(7):756-63. Epub 2013 May 26.

Campbell Family Institute for Cancer Research, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

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July 2013

Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo.

Proc Natl Acad Sci U S A 2012 Sep 10;109(39):15871-6. Epub 2012 Sep 10.

Department of Clinical and Experimental Medicine, Faculty for Health Sciences, Linköping University, 58285 Linköping, Sweden.

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September 2012

IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors.

Blood 2011 Aug 7;118(5):1283-90. Epub 2011 Jun 7.

Department of Clinical and Experimental Medicine, Experimental Hematopoiesis Unit, Faculty for Health Sciences, Linköping University, Linköping, Sweden.

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August 2011

A dose-dependent role for EBF1 in repressing non-B-cell-specific genes.

Eur J Immunol 2011 Jun 9;41(6):1787-93. Epub 2011 May 9.

Integrated Department of Immunology, National Jewish Health, Denver, CO 80206, USA.

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June 2011

Load and lock: the molecular mechanisms of B-lymphocyte commitment.

Immunol Rev 2010 Nov;238(1):47-62

Experimental Hematopoiesis Unit, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.

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November 2010

Interleukin-7-induced Stat-5 acts in synergy with Flt-3 signaling to stimulate expansion of hematopoietic progenitor cells.

J Biol Chem 2010 Nov 9;285(47):36275-84. Epub 2010 Sep 9.

Department of Clinical and Experimental Medicine, Experimental Hematopoiesis Unit, Faculty for Health Sciences, IKE Linköping University, 58185 Linköping, Sweden.

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November 2010

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion.

Proc Natl Acad Sci U S A 2010 Mar 18;107(12):5465-70. Epub 2010 Mar 18.

Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.

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March 2010

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.

Blood 2010 Apr 8;115(13):2601-9. Epub 2009 Dec 8.

Department for Clinical and Experimental Sciences, Linköping University, Linköping, Sweden.

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April 2010

Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes.

Blood 2007 May 11;109(9):3697-705. Epub 2007 Jan 11.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Klinikgatan 26, 221 84 Lund, Sweden.

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May 2007