Dr. Sasan Saket, MD - Shahid Beheshti University of Medical Sciences - Assistant Professor of Child Neurology

Dr. Sasan Saket

MD

Shahid Beheshti University of Medical Sciences

Assistant Professor of Child Neurology

Tehran, Tehran | Iran (Islamic Republic of)

Main Specialties: Child Neurology, Pediatrics

Additional Specialties: Child Neurology

ORCID logohttps://orcid.org/0000-0002-7118-0964

Dr. Sasan Saket, MD - Shahid Beheshti University of Medical Sciences - Assistant Professor of Child Neurology

Dr. Sasan Saket

MD

Introduction

Primary Affiliation: Shahid Beheshti University of Medical Sciences - Tehran, Tehran , Iran (Islamic Republic of)

Specialties:

Additional Specialties:

Research Interests:


View Dr. Sasan Saket’s Resume / CV

Education

Nov 2014
Iranian Child Neurology Center of Excellence (ICNCE)
Subspeciality in Child Neurology
Shahid Beheshti University of Medical Sciences

Publications

9Publications

171Reads

84Profile Views

14PubMed Central Citations

Pachyonychia congenita: a case report of a successful treatment with rosuvastatin in a patient with a KRT6A mutation

British Journal of Dermatology

Pachyonychia congenita (PC) is a rare autosomal dominant disorder characterized by nail dystrophy and palmoplantar keratoderma with severe plantar pain affecting quality of life. There is no effective treatment. Heterozygous mutations in the keratin genes KRT6A, KRT6B, KRT6C, KRT16 and KRT17 have been reported as a cause of PC. Herein we present a female patient with an amino acid substitution mutation in KRT6A (c.1381G>A, p.Glu461Lys in exon 7) and classic features of PC associated with oral leucokeratosis and follicular hyperkeratosis. We also demonstrate successful treatment of the patient with rosuvastatin. A 3.6-mm reduction in plantar callosity thickness was demonstrated by sonography. Our patient also experienced significant pain relief that allowed her to increase physical activity (Children’s Dermatology Life Quality Index score dropped nine points following treatment). Collectively, these improvements suggest that rosuvastatin may offer a promising treatment for PC.

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September 2018
2 Reads

Hopkins Syndrome in a 14 Year Old Boy; a Case Report.

Emerg (Tehran) 2018 16;6(1):e23. Epub 2018 Apr 16.

Emergency Department, Shohadaye Tajrish Hospital, Shahaid Beheshti University of Medical Sciences, Tehran, Iran.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036531PMC
April 2018
23 Reads

GM2-Gangliosidosis (Sandhoff and Tay Sachs disease): Diagnosis and Neuroimaging Findings (An Iranian Pediatric Case Series).

Iran J Child Neurol 2014 ;8(3):55-60

Pediatric Neurology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran ; Pediatric Neurology Center of Excellence, Department of Pediatric Neurology, Mofid Children Hospital, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135282PMC
August 2014
40 Reads
7 Citations

Helicobacter pylori (IgG) assessment among children (1-14 years old) referred to Shahid Madani children's hospital in 2011-2012

Yafteh. 2014; 16 (1) :14-22

Yafte

Background: Helicobacter pylori is a microorganism which results in gastritis, peptic ulcer and is linked to GI malignancies. This bacteria has an important role in GI disease .there is not enough data about prevalence of H.P infection among children (1-14 years old) in Lorestan province so this study performed to determine the sero-prevalence of H.P among children who were visited in Shahid Madani Children's Hospital of Khorram abad and also dealt with the study of risk factors related to it. Material and methods: This is an analytical epidemiologic study performed during 1390-1391. First children’s parents were interviewed and after filling a questionnaire and a documented consent; a blood sample was obtained from the child in order to determine serum level of H.P IgG (ELISA). Demographic data such as age, gender, mother’s education, father’s job, was recorded in the questionnaire .Then statistical analysis was performed. Findings: In this research 200 children (1-14 years old) were studied to determine H.Pylori antibody prevalence. The average age of the children was 5.1 ± 2.9. 61% of them were male and 39% were female. Based on age, H.Pylori was most common among children aged 10-14 years old (57.9%) and the least prevalence among children under 1 year old was (16.7%) according to Fisher exact test this difference was significant (p=0.032). In statistical analysis H.pylori infection prevalence was significantly higher (54.2%) among low income families (income <250000 Toman) and this was important (p=0.006). The prevalence was not significant among children living in cities with those living in villages (p=0.83). Conclusions: Based on serum levels of antibody of H pilory antibody there is a linear relationship between the prevalence of this infection and age ،height and the present weight of the child (p<0/05).It means that with age, height and weight, the amount of serum antibody of H.pylori increases significantly. H.pylori infection prevalence was significantly higher among low income families (income <250000 Toman).

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July 2014
12 Reads

Evaluation of one hundred pediatric muscle biopsies during a 2-year period in mofid children and toos hospitals.

Iran J Child Neurol 2013 ;7(2):17-21

Professor of Pediatric Neurology, Pediatric Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran ; Professor of Pediatric Neurology, Pediatric Neurology Department, Mofid Children Hospital, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943040PMC
March 2014
30 Reads

Prevalence of Preterm Neonates and Risk Factors

2011 - August - 2 (2)

Iranian Journal of Neonatology

Introduction

Preterm birth is still a major health problem throughout the world. Preterm birth results in 75% of neonatal mortality. We sought to identify risk factors which cause preterm birth.

Materials and Methods

This cross-sectional study assessed all preterm neonates born in Asali Hospital in Khorram Abad (either by NVD or C/S) during the first 6 months of 2007. Sampling method was census. Fetal sex, maternal disease, maternal addiction to cigarettes, maternal age, placental problems, number of gravidities, PROM, preeclampsia, multifetal gestation, Apgar score, uterine anomaly were the variables studied in this survey. Questionnaires were used to collect the data and the data was analyzed with SPSS software.

Results

183 of 2179 live neonates borne in Asali hospital were preterm (8.4%). The most common factors related to preterm birth were: Primigravidity(56.3%), PROM(35.5%), preterm labor pain(33.8%), maternal disease(22.4%), preeclampsia(21.9%), multifetal gestation(19.7%), previous abortion(18.6%), previous preterm delivery(9.8%), high risk maternal age(10.4%) and placental problems(7.7%). Preterm labor pain was significantly more common among multiparus women in comparison with nulipara ones(x2=16.5, p=0.000049) but occurrence of PROM(x2=0.57, p=0.45), preeclampsia(x2=0.8, p=0.37), maternal chronic disease(x2=0.55, p=0.46) and multifetal gestation(x2=0.01, p=0.91) was not significantly different among multipara and primipara women.

Conclusion

Several factors related to preterm birth can be prevented by health modalities. Maternal education and giving advanced information to mothers in prenatal health care visits, preterm birth and its side effects may be reduced.

Key words

Preterm neonate, preterm birth, premature birth

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August 2011
1 Read

PFEIFFER TYPE I SYNDROME: A GENETICALLY PROVEN CASE REPORT

June 2008

Iran J Child Neurology

Objective

Pfeiffer Syndrome is as rare as Apert syndrome in the Western population. This condition is very rare in the Asian population. At the best of our knowledge this is the first genetically proven case report from Iran. The authors report with a review of literature, the case of a infant with Pfeiffer syndrome, manifested by Lacunar skull, ventriculomegaly, bicoronal craniosynostosis,frontal bossing, shallow orbits, parrot-like nose, umbilical hernia, broad and medially deviated great toes.

Keywords: Acrocephalosyndactylia, Craniosynostoses, Broad and great toes, Pfeiffer, Syndrome

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June 2008