Publications by authors named "Sarka Pospisilova"

100Publications

Epilepsy miRNA Profile Depends on the Age of Onset in Humans and Rats.

Front Neurosci 2020 15;14:924. Epub 2020 Sep 15.

Central European Institute of Technology, Masaryk University, Brno, Czechia.

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http://dx.doi.org/10.3389/fnins.2020.00924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522367PMC
September 2020

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL.

Blood 2020 Sep 29. Epub 2020 Sep 29.

Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.

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http://dx.doi.org/10.1182/blood.2020007039DOI Listing
September 2020

Consensus-Based Pharmacophore Mapping for New Set of -(disubstituted-phenyl)-3-hydroxyl-naphthalene-2-carboxamides.

Int J Mol Sci 2020 Sep 9;21(18). Epub 2020 Sep 9.

Division of Biologically Active Complexes and Molecular Magnets, Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacky University, Slechtitelu 27, 78371 Olomouc, Czech Republic.

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http://dx.doi.org/10.3390/ijms21186583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555178PMC
September 2020

Insight into antimicrobial activity of substituted phenylcarbamoyloxypiperazinylpropanols.

Bioorg Chem 2020 Sep 30;102:104060. Epub 2020 Jun 30.

Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacky University, Slechtitelu 27, 783 71 Olomouc, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2020.104060DOI Listing
September 2020

Dibasic Derivatives of Phenylcarbamic Acid as Prospective Antibacterial Agents Interacting with Cytoplasmic Membrane.

Antibiotics (Basel) 2020 Feb 6;9(2). Epub 2020 Feb 6.

Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacky University, Slechtitelu 27, 783 71 Olomouc, Czech Republic.

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http://dx.doi.org/10.3390/antibiotics9020064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168207PMC
February 2020

Novel genetic variant of HPS1 gene in Hermansky-Pudlak syndrome with fulminant progression of pulmonary fibrosis: a case report.

BMC Pulm Med 2019 Oct 16;19(1):178. Epub 2019 Oct 16.

Department of Internal Medicine, Hematology and Oncology, University Hospital and Faculty of Medicine, Jihlavská 20, 625 00, Brno, Czech Republic.

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http://dx.doi.org/10.1186/s12890-019-0941-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794755PMC
October 2019

Profiling of biological and environmental risk factors in immunogenetic subgroups of chronic lymphocytic leukemia - Czech national study.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2019 Sep 26. Epub 2019 Sep 26.

Department of Internal Medicine - Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.5507/bp.2019.046DOI Listing
September 2019

Activity of N-Phenylpiperazine Derivatives Against Bacterial and Fungal Pathogens.

Curr Protein Pept Sci 2019 ;20(11):1119-1129

Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacky University, Olomouc, Czech Republic.

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http://dx.doi.org/10.2174/1389203720666190913114041DOI Listing
March 2020

Bioactivity of Methoxylated and Methylated 1-Hydroxynaphthalene-2-Carboxanilides: Comparative Molecular Surface Analysis.

Molecules 2019 Aug 18;24(16). Epub 2019 Aug 18.

Division of Biologically Active Complexes and Molecular Magnets, Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacký University, Šlechtitelů 27, 78371 Olomouc, Czech Republic.

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http://dx.doi.org/10.3390/molecules24162991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720605PMC
August 2019

Detection of a deletion at 22q11 locus involving ZNF280A/ZNF280B/PRAME/GGTLC2 in B-cell malignancies: simply a consequence of an immunoglobulin lambda light chain rearrangement.

Br J Haematol 2019 08 15;186(4):e91-e94. Epub 2019 Apr 15.

Department of Internal Medicine, Haematology and Oncology, University Hospital Brno and Faculty of Medicine MU, Brno, Czech Republic.

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http://dx.doi.org/10.1111/bjh.15922DOI Listing
August 2019

The importance of complex karyotype in prognostication and treatment of chronic lymphocytic leukemia (CLL): a comprehensive review of the literature.

Leuk Lymphoma 2019 10 18;60(10):2348-2355. Epub 2019 Feb 18.

Department of Internal Medicine - Hematology and Oncology, Medical Faculty MU and University Hospital Brno , Brno , Czech Republic.

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http://dx.doi.org/10.1080/10428194.2019.1576038DOI Listing
October 2019

Telomere dynamics in adult hematological malignancies.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2019 Feb 10;163(1):1-7. Epub 2019 Jan 10.

Center of Molecular Medicine, Central European Institute of Technology, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.5507/bp.2018.084DOI Listing
February 2019

MicroRNA-210 expression during childbirth and postpartum as a potential biomarker of acute fetal hypoxia.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2019 Sep 18;163(3):259-264. Epub 2018 Dec 18.

Center of Molecular Medicine, CEITEC - Central European Institute of Technology, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.5507/bp.2018.075DOI Listing
September 2019

aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics.

Haematologica 2018 12 15;103(12):1956-1968. Epub 2018 Nov 15.

Internal Medicine III, Ulm University, Germany and Innere Medizin I, Universitätsklinikum des Saarlandes, Homburg, Germany.

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.187583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269313PMC
December 2018

A novel germline mutation in GP1BA gene N-terminal domain in monoallelic Bernard-Soulier syndrome.

Platelets 2018 Dec 17;29(8):827-833. Epub 2018 Oct 17.

a Department of Internal Medicine- Hematology and Oncology, University Hospital Brno and Faculty of Medicine , Masaryk University , Brno , Czech Republic.

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https://www.tandfonline.com/doi/full/10.1080/09537104.2018.1
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http://dx.doi.org/10.1080/09537104.2018.1529300DOI Listing
December 2018

Synthesis and Spectrum of Biological Activities of Novel N-arylcinnamamides.

Int J Mol Sci 2018 Aug 7;19(8). Epub 2018 Aug 7.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Odbojarov 10, 83232 Bratislava, Slovakia.

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http://dx.doi.org/10.3390/ijms19082318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121455PMC
August 2018

C-terminal RUNX1 mutation in familial platelet disorder with predisposition to myeloid malignancies.

Int J Hematol 2018 Dec 6;108(6):652-657. Epub 2018 Aug 6.

Central European Institute of Technology (CEITEC), University Hospital, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.1007/s12185-018-2514-3DOI Listing
December 2018

ToTem: a tool for variant calling pipeline optimization.

BMC Bioinformatics 2018 06 26;19(1):243. Epub 2018 Jun 26.

Center of Molecular Medicine, Central European Institute of Technology, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.1186/s12859-018-2227-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020218PMC
June 2018

In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci.

Bioorg Med Chem Lett 2018 07 14;28(12):2184-2188. Epub 2018 May 14.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Odbojarov 10, 832 32 Bratislava, Slovakia. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.05.011DOI Listing
July 2018

The Role of Oncogenic Tyrosine Kinase NPM-ALK in Genomic Instability.

Cancers (Basel) 2018 Mar 5;10(3). Epub 2018 Mar 5.

Central European Institute of Technology (CEITEC), Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.

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http://dx.doi.org/10.3390/cancers10030064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876639PMC
March 2018

Primaquine hybrids as promising antimycobacterial and antimalarial agents.

Eur J Med Chem 2018 Jan 2;143:769-779. Epub 2017 Dec 2.

University of Zagreb, Faculty of Pharmacy and Biochemistry, A. Kovačića 1, 10 000 Zagreb, Croatia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234173098
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http://dx.doi.org/10.1016/j.ejmech.2017.11.083DOI Listing
January 2018

Transcription factor YY1 can control AID-mediated mutagenesis in mice.

Eur J Immunol 2018 02 14;48(2):273-282. Epub 2017 Nov 14.

Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA.

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http://doi.wiley.com/10.1002/eji.201747065
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http://dx.doi.org/10.1002/eji.201747065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884117PMC
February 2018

Next-generation sequencing in chronic lymphocytic leukemia: recent findings and new horizons.

Oncotarget 2017 Sep 24;8(41):71234-71248. Epub 2017 Jul 24.

Central European Institute of Technology, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.18632/oncotarget.19525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642634PMC
September 2017

Fragment analysis represents a suitable approach for the detection of hotspot c.7541_7542delCT NOTCH1 mutation in chronic lymphocytic leukemia.

Leuk Res 2017 09 7;60:145-150. Epub 2017 Aug 7.

Central European Institute of Technology (CEITEC) and Faculty of Medicine, Masaryk University, Kamenice 5, CZ-625 00 Brno, Czech Republic; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Cernopolni 9, CZ-613 00 Brno, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2017.08.001DOI Listing
September 2017

MicroRNA and mesial temporal lobe epilepsy with hippocampal sclerosis: Whole miRNome profiling of human hippocampus.

Epilepsia 2017 10 16;58(10):1782-1793. Epub 2017 Aug 16.

Central European Institute of Technology, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.1111/epi.13870DOI Listing
October 2017

Chronic lymphocytic leukemia: A prognostic model comprising only two biomarkers (IGHV mutational status and FISH cytogenetics) separates patients with different outcome and simplifies the CLL-IPI.

Am J Hematol 2017 Apr 13;92(4):375-380. Epub 2017 Feb 13.

Department of Hematology, Institute of Hematology and Oncology, Hospital Clínic, IDIBAPS, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/ajh.24660DOI Listing
April 2017

Comparison of MicroRNA Content in Plasma and Urine Indicates the Existence of a Transrenal Passage of Selected MicroRNAs.

Adv Exp Med Biol 2016 ;924:97-100

Department of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General Faculty Hospital in Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1007/978-3-319-42044-8_18DOI Listing
September 2017

Synthesis and Antimicrobial Evaluation of 1-[(2-Substituted phenyl)carbamoyl]naphthalen-2-yl Carbamates.

Molecules 2016 Sep 7;21(9). Epub 2016 Sep 7.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Odbojarov 10, Bratislava 83232, Slovakia.

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http://dx.doi.org/10.3390/molecules21091189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273964PMC
September 2016

N-Alkoxyphenylhydroxynaphthalenecarboxamides and Their Antimycobacterial Activity.

Molecules 2016 Aug 16;21(8). Epub 2016 Aug 16.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Odbojarov 10, Bratislava 83232, Slovakia.

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http://dx.doi.org/10.3390/molecules21081068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273036PMC
August 2016

Ibrutinib inhibits CD20 upregulation on CLL B cells mediated by the CXCR4/SDF-1 axis.

Blood 2016 09 1;128(12):1609-13. Epub 2016 Aug 1.

Central European Institute of Technology, Masaryk University, Brno, Czech Republic; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic;

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http://dx.doi.org/10.1182/blood-2016-04-709519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291297PMC
September 2016

Differentially expressed miRNAs in trisomy 21 placentas.

Prenat Diagn 2016 Aug 18;36(8):775-84. Epub 2016 Jul 18.

Institute of Biology and Medical Genetics of the First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.

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http://dx.doi.org/10.1002/pd.4861DOI Listing
August 2016

Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?

Haematologica 2016 Mar;101(3):263-5

Division of Experimental Oncology and Department of Onco-Hematology, Università Vita-Salute San Raffaele and IRCCS Instituto Scientifico San Raffaele, Milan, Italy

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http://dx.doi.org/10.3324/haematol.2015.139246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815716PMC
March 2016

ROR1-based immunomagnetic protocol allows efficient separation of CLL and healthy B cells.

Br J Haematol 2016 10 16;175(2):339-342. Epub 2015 Nov 16.

Institute of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.1111/bjh.13848DOI Listing
October 2016

Histone H1 Differentially Inhibits DNA Bending by Reduced and Oxidized HMGB1 Protein.

PLoS One 2015 25;10(9):e0138774. Epub 2015 Sep 25.

Central European Institute of Technology (CEITEC) Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138774PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583294PMC
May 2016

The impact of standard chemotherapy on miRNA signature in plasma in AML patients.

Leuk Res 2015 Dec 20;39(12):1389-95. Epub 2015 Aug 20.

Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University in Prague and General Faculty Hospital in Prague, Albertov 4, 128 00 Prague, Czech Republic; Medical Faculty in Pilsen, Charles University in Prague, Husova 3, 306 05 Pilsen, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2015.08.009DOI Listing
December 2015

Urinary Cell-Free DNA Quantification as Non-Invasive Biomarker in Patients with Bladder Cancer.

Urol Int 2016 3;96(1):25-31. Epub 2015 Sep 3.

Department of Urology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1159/000438828DOI Listing
December 2016

Oxidative stress as a therapeutic perspective for ATM-deficient chronic lymphocytic leukemia patients.

Haematologica 2015 Aug;100(8):994-6

CEITEC - Center of Molecular Medicine, Masaryk University, Brno and Department of Internal Medicine - Hematology and Oncology, University Hospital Brno

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http://dx.doi.org/10.3324/haematol.2015.130260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004413PMC
August 2015

Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia.

Clin Cancer Res 2016 Jan 3;22(2):459-69. Epub 2015 Aug 3.

Institute of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic. Department of Cytokinetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716000PMC
January 2016

Salicylanilide carbamates: Promising antibacterial agents with high in vitro activity against methicillin-resistant Staphylococcus aureus (MRSA).

Eur J Pharm Sci 2015 Sep 13;77:197-207. Epub 2015 Jun 13.

Department of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1/3, 612 42 Brno, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2015.06.009DOI Listing
September 2015

NOD/SCID IL2Rγ-null mouse xenograft model of human p53-mutated chronic lymphocytic leukemia and ATM-mutated mantle cell lymphoma using permanent cell lines.

Leuk Lymphoma 2015 12;56(11):3198-206. Epub 2015 May 12.

a Department of Internal Medicine , Hematology and Oncology, University Hospital Brno and Faculty of Medicine , Masaryk University Brno, Czech Republic.

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http://dx.doi.org/10.3109/10428194.2015.1034701DOI Listing
September 2016

Analysis of prognostic significance of merkel cell polyomavirus in chronic lymphocytic leukemia.

Clin Lymphoma Myeloma Leuk 2015 Jul 11;15(7):439-42. Epub 2015 Feb 11.

Department of Internal Medicine-Hematology and Oncology, University Hospital Brno, Czech Republic; Central European Institute of Technology (CEITEC), Masaryk University Brno, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2015.02.003DOI Listing
July 2015

In vitro bactericidal activity of 4- and 5-chloro-2-hydroxy-N-[1-oxo-1-(phenylamino)alkan-2-yl]benzamides against MRSA.

Biomed Res Int 2015 15;2015:349534. Epub 2015 Jan 15.

Department of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1/3, 612 42 Brno, Czech Republic.

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http://dx.doi.org/10.1155/2015/349534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321674PMC
November 2015

Ofatumumab added to dexamethasone in patients with relapsed or refractory chronic lymphocytic leukemia: Results from a phase II study.

Am J Hematol 2015 May 1;90(5):417-21. Epub 2015 Apr 1.

Department of Internal Medicine-Hematology and Oncology, University Hospital Brno, Brno, Czech Republic; Central European Institute of Technology (CEITEC), Masaryk University Brno, Brno, Czech Republic.

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http://dx.doi.org/10.1002/ajh.23964DOI Listing
May 2015

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.

Blood 2015 Jan 17;125(5):856-9. Epub 2014 Dec 17.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Institute of Applied Biosciences, Centre for Research and Technology-Hellas, Thessaloniki, Greece; Hematology Department and Hematopoietic Cell Transplantation Unit, Georgios Papanicolaou Hospital, Thessaloniki, Greece;

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http://www.bloodjournal.org/content/bloodjournal/125/5/856.f
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-09-60
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http://dx.doi.org/10.1182/blood-2014-09-600874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311230PMC
January 2015