Saraswati Sukumar

Saraswati Sukumar

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Saraswati Sukumar

Publications by authors named "Saraswati Sukumar"

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100Publications

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Targeted nanopore sequencing with Cas9-guided adapter ligation.

Nat Biotechnol 2020 Feb 10. Epub 2020 Feb 10.

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41587-020-0407-5DOI Listing
February 2020

Discovery of a Potent GLUT Inhibitor from a Library of Rapafucins by Using 3D Microarrays.

Angew Chem Int Ed Engl 2019 Nov 31;58(48):17158-17162. Epub 2019 Oct 31.

Department of Pharmacology and Molecular Sciences, The SJ Yan and HJ Mao Laboratory of Chemical Biology, Johns Hopkins University School of Medicine, Room 516, Hunterian Building, 725 N. Wolfe Street, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/anie.201905578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861656PMC
November 2019

Quantitation of DNA Methylation by Quantitative Multiplex Methylation-Specific PCR (QM-MSP) Assay.

Methods Mol Biol 2018 ;1708:473-496

Breast and Ovarian Cancer Program, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 1650 Orleans St., CRB1, RM 143, Baltimore, MD, 21321, USA.

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http://dx.doi.org/10.1007/978-1-4939-7481-8_24DOI Listing
July 2018

Inhibition of platelet function using liposomal nanoparticles blocks tumor metastasis.

Theranostics 2017 26;7(5):1062-1071. Epub 2017 Feb 26.

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing 100190, China.

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http://dx.doi.org/10.7150/thno.17908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399576PMC
January 2018

Monitoring of Serum DNA Methylation as an Early Independent Marker of Response and Survival in Metastatic Breast Cancer: TBCRC 005 Prospective Biomarker Study.

J Clin Oncol 2017 Mar 21;35(7):751-758. Epub 2016 Nov 21.

Kala Visvanathan, Johns Hopkins University School of Medicine and Bloomberg School of Public Health; MaryJo S. Fackler, Zhe Zhang, Zoila A. Lopez-Bujanda, Stacie C. Jeter, Lori J. Sokoll, Leslie M. Cope, Christopher B. Umbricht, David M. Euhus, Saraswati Sukumar, and Antonio C. Wolff, Johns Hopkins University School of Medicine, Baltimore, MD; Elizabeth Garrett-Mayer, Medical University of South Carolina, Charleston, SC; Andres Forero, University of Alabama at Birmingham, Birmingham, AL; Anna M. Storniolo, Indiana University, Bloomington, IN; Rita Nanda, University of Chicago, Chicago, IL; Nancy U. Lin, Dana-Farber Cancer Institute, Boston, MA; Lisa A. Carey, University of North Carolina, Chapel Hill, NC; and James N. Ingle, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1200/JCO.2015.66.2080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455421PMC
March 2017

Guidelines for the selection of functional assays to evaluate the hallmarks of cancer.

Biochim Biophys Acta 2016 12 11;1866(2):300-319. Epub 2016 Oct 11.

MTA TTK Lendület Cancer Biomarker Research Group, Magyar tudósok körútja 2, H-1117 Budapest, Hungary; 2nd Department of Pediatrics, Semmelweis University, H-1094 Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2016.10.002DOI Listing
December 2016

The dual role of FOXF2 in regulation of DNA replication and the epithelial-mesenchymal transition in breast cancer progression.

Cell Signal 2016 10 1;28(10):1502-19. Epub 2016 Jul 1.

Breast Cancer Program, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056599PMC
http://dx.doi.org/10.1016/j.cellsig.2016.06.021DOI Listing
October 2016

The Widening Sphere of Influence of HOXB7 in Solid Tumors.

Cancer Res 2016 05 20;76(10):2857-62. Epub 2016 Apr 20.

Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-3444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874556PMC
May 2016

HOX genes: Major actors in resistance to selective endocrine response modifiers.

Biochim Biophys Acta 2016 Apr 22;1865(2):105-10. Epub 2016 Jan 22.

Breast Cancer Program, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2016.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860125PMC
April 2016

A Self-Folding Hydrogel In Vitro Model for Ductal Carcinoma.

Tissue Eng Part C Methods 2016 Apr 16;22(4):398-407. Epub 2016 Mar 16.

1 Department of Chemical and Biomolecular Engineering, Johns Hopkins University , Baltimore, Maryland.

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http://dx.doi.org/10.1089/ten.TEC.2015.0442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827285PMC
April 2016

A pivotal role for HOXB7 protein in endocrine resistant breast cancer.

Oncoscience 2015 15;2(11):917-9. Epub 2015 Nov 15.

Breast Cancer Program, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675788PMC
http://dx.doi.org/10.18632/oncoscience.263DOI Listing
December 2015

Phosphoproteomic Analysis Identifies Focal Adhesion Kinase 2 (FAK2) as a Potential Therapeutic Target for Tamoxifen Resistance in Breast Cancer.

Mol Cell Proteomics 2015 Nov 1;14(11):2887-900. Epub 2015 Sep 1.

From the ‡McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; ¶Department of Oncology; ‖Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231

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http://dx.doi.org/10.1074/mcp.M115.050484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638033PMC
November 2015

Improvement of Stability and Efficacy of C16Y Therapeutic Peptide via Molecular Self-Assembly into Tumor-Responsive Nanoformulation.

Mol Cancer Ther 2015 Oct 12;14(10):2390-400. Epub 2015 Aug 12.

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing, China.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0484DOI Listing
October 2015

A breast cancer cell microarray (CMA) as a rapid method to characterize candidate biomarkers.

Cancer Biol Ther 2014 ;15(12):1593-9

a McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry ; Johns Hopkins University School of Medicine ; Baltimore , MD USA.

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http://dx.doi.org/10.4161/15384047.2014.961886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622654PMC
September 2015

Multiplexed detection of serological cancer markers with plasmon-enhanced Raman spectro-immunoassay.

Chem Sci 2015 Jul;6(7):3906-3914

Department of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States ; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, United States.

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http://dx.doi.org/10.1039/C5SC01054CDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577055PMC
July 2015

Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer.

Cell Rep 2015 Jun 4;11(10):1549-63. Epub 2015 Jun 4.

Department of Medical Oncology, Dana-Farber Cancer Institute Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; BBS Program, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; The Broad Institute, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.05.011DOI Listing
June 2015

Do breast cancer cell lines provide a relevant model of the patient tumor methylome?

PLoS One 2014 26;9(8):e105545. Epub 2014 Aug 26.

Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105545PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144876PMC
May 2015

HOXB7 promotes malignant progression by activating the TGFβ signaling pathway.

Cancer Res 2015 Feb 26;75(4):709-19. Epub 2014 Dec 26.

Department of Biological Science, University of South Carolina, Columbia, South Carolina. Center for Colon Cancer Research, University of South Carolina, Columbia, South Carolina.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352303PMC
February 2015

Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis.

Nat Commun 2014 Sep 2;5:4715. Epub 2014 Sep 2.

1] Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA [2] Department of Chemical and Biomolecular Engineering, School of Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA [3] Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1038/ncomms5715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351998PMC
September 2014

Activation of diverse signalling pathways by oncogenic PIK3CA mutations.

Nat Commun 2014 Sep 23;5:4961. Epub 2014 Sep 23.

1] McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry, Johns Hopkins University School of Medicine, 733 North Broadway, BRB 527, Baltimore, Maryland 21205, USA [2] Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA [3] Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1038/ncomms5961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210192PMC
September 2014

Combining the strength of genomics, nanoparticle technology, and direct intraductal delivery for breast cancer treatment.

Breast Cancer Res 2014 May 17;16(2):306. Epub 2014 May 17.

Breast Cancer Program, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 1650, Orleans Street, CRB1/143, Baltimore, MD, 21231, USA.

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http://dx.doi.org/10.1186/bcr3656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053158PMC
May 2014

Novel methylated biomarkers and a robust assay to detect circulating tumor DNA in metastatic breast cancer.

Cancer Res 2014 Apr;74(8):2160-70

Authors' Affiliations: Departments of Oncology, Surgery, and Surgical Pathology, Johns Hopkins University School of Medicine; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore Maryland; Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York; Departments of Oncology and Surgery, Mayo Clinic, Rochester, Minnesota; Department of Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; and Department of Medicine, University of North Carolina, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327879PMC
April 2014

Genetic and phenotypic diversity in breast tumor metastases.

Cancer Res 2014 Mar 21;74(5):1338-48. Epub 2014 Jan 21.

Authors' Affiliations: Departments of Medical Oncology and Biostatistics and Computational Biology, Dana-Farber Cancer Institute; Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School; Department of Biostatistics, Harvard School of Public Health, Boston; Departments of Physics and Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; Harvard Stem Cell Institute, Cambridge, Massachusetts; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Medical Oncology, Hospital Clinic, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain; Department of Pathology, MizMedi Hospital, Seoul, South Korea; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel; and Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2357-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963810PMC
March 2014

HMGA1: a master regulator of tumor progression in triple-negative breast cancer cells.

PLoS One 2013 2;8(5):e63419. Epub 2013 May 2.

Hematology Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063419PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642138PMC
December 2013

Big punches come in nanosizes for chemoprevention.

Cancer Prev Res (Phila) 2013 Oct 26;6(10):1007-10. Epub 2013 Sep 26.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231. and Dipali Sharma,

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http://cancerpreventionresearch.aacrjournals.org/cgi/doi/10.
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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994998PMC
October 2013

Molecular pathways: current role and future directions of the retinoic acid pathway in cancer prevention and treatment.

Clin Cancer Res 2013 Apr 15;19(7):1651-9. Epub 2013 Jan 15.

Breast Cancer Program, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-12-3175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618522PMC
April 2013

Cytoplasmic mislocalization of overexpressed FOXF1 is associated with the malignancy and metastasis of colorectal adenocarcinomas.

Exp Mol Pathol 2013 Feb 24;94(1):262-9. Epub 2012 Oct 24.

Department of Biological Sciences, Center for Colon Cancer Research, University of South Carolina, Columbia, SC 29208, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001448001200161
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http://dx.doi.org/10.1016/j.yexmp.2012.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562381PMC
February 2013

ADP ribosylation by PARP-1 suppresses HOXB7 transcriptional activity.

PLoS One 2012 23;7(7):e40644. Epub 2012 Jul 23.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040644PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402478PMC
November 2012

Collagen I fiber density increases in lymph node positive breast cancers: pilot study.

J Biomed Opt 2012 Nov;17(11):116017

The Johns Hopkins University School of Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1117/1.JBO.17.11.116017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486274PMC
November 2012

Somatic mutations in the Notch, NF-KB, PIK3CA, and Hedgehog pathways in human breast cancers.

Genes Chromosomes Cancer 2012 May 3;51(5):480-9. Epub 2012 Feb 3.

Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

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http://doi.wiley.com/10.1002/gcc.21935
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http://dx.doi.org/10.1002/gcc.21935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302210PMC
May 2012

Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition.

Cancer Res 2012 Mar 26;72(6):1384-94. Epub 2012 Jan 26.

Department of Cardiothoracic Surgery and Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, New York, New York, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-2905DOI Listing
March 2012

Altered antisense-to-sense transcript ratios in breast cancer.

Proc Natl Acad Sci U S A 2012 Feb 22;109(8):2820-4. Epub 2010 Nov 22.

Department of Medical Oncology, and Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://www.pnas.org/content/109/8/2820.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.1010559107
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http://dx.doi.org/10.1073/pnas.1010559107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286925PMC
February 2012

The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function.

Cell Signal 2012 Jan 22;24(1):316-24. Epub 2011 Sep 22.

Department of Biological Sciences, University of South Carolina, Columbia, South Carolina 29208, USA.

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http://dx.doi.org/10.1016/j.cellsig.2011.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205208PMC
January 2012

Methylated genes in breast cancer: associations with clinical and histopathological features in a familial breast cancer cohort.

Cancer Biol Ther 2011 May 15;11(10):853-65. Epub 2011 May 15.

The University of North Carolina at Chapel Hill School of Nursing, Chapel Hill, NC, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116929PMC
http://dx.doi.org/10.4161/cbt.11.10.15177DOI Listing
May 2011

BRCA1: linking HOX to breast cancer suppression.

Breast Cancer Res 2010 23;12(4):306. Epub 2010 Jul 23.

Breast Cancer Program, Sidney Kimmel Comprehensive Cancer Center at Johns, Hopkins, Johns Hopkins University School of Medicine, 1650 Orleans Street, Room 143 CRB1, Baltimore, MD 21231, USA.

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http://breast-cancer-research.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/bcr2600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949630PMC
March 2011

Functional activation of the estrogen receptor-α and aromatase by the HDAC inhibitor entinostat sensitizes ER-negative tumors to letrozole.

Cancer Res 2011 Mar 18;71(5):1893-903. Epub 2011 Jan 18.

Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine and University of Maryland Greenebaum Cancer Center, Baltimore, Maryland 21201, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-10-2458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076193PMC
March 2011

Gene expression profiling of human breast tissue samples using SAGE-Seq.

Genome Res 2010 Dec 2;20(12):1730-9. Epub 2010 Nov 2.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1101/gr.108217.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989999PMC
December 2010

Epithelial cell adhesion molecule (EpCAM) is overexpressed in breast cancer metastases.

Breast Cancer Res Treat 2010 Oct 11;123(3):701-8. Epub 2009 Dec 11.

Department of Pathology, Johns Hopkins Hospital, Weinberg 2242, 401 North Broadway, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1007/s10549-009-0671-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042397PMC
October 2010

Evaluation of promoter hypermethylation detection in serum as a diagnostic tool for breast carcinoma in Korean women.

Gynecol Oncol 2010 Aug 13;118(2):176-81. Epub 2010 May 13.

Department of Pathology, School of Medicine, Jeju National University, Jejusi, Republic of Korea.

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http://dx.doi.org/10.1016/j.ygyno.2010.04.016DOI Listing
August 2010

DNA methylation-related vitamin D receptor insensitivity in breast cancer.

Cancer Biol Ther 2010 Jul 9;10(1):44-53. Epub 2010 Jul 9.

Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087945PMC
http://dx.doi.org/10.4161/cbt.10.1.11994DOI Listing
July 2010

Quantitative assessment of DNA methylation for the detection of cervical neoplasia in liquid-based cytology specimens.

Virchows Arch 2010 Jul 23;457(1):35-42. Epub 2010 May 23.

Department of Pathology, School of Medicine, Jeju National University, Jejusi, Republic of Korea.

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http://link.springer.com/10.1007/s00428-010-0936-2
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http://dx.doi.org/10.1007/s00428-010-0936-2DOI Listing
July 2010

Epigenetic inactivation of the potential tumor suppressor gene FOXF1 in breast cancer.

Cancer Res 2010 Jul 29;70(14):6047-58. Epub 2010 Jun 29.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909657PMC
July 2010

Intraductal therapy for the prevention of breast cancer.

Curr Opin Investig Drugs 2010 Jun;11(6):646-52

Johns Hopkins University, 600 North Wolfe Street, Osler 624, Baltimore, MD 21287, USA.

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June 2010

Basal-like breast cancer displays distinct patterns of promoter methylation.

Cancer Biol Ther 2010 Jun 18;9(12):1017-24. Epub 2010 Jun 18.

Department of Pathology, Chonnam National University Medical School and Research Institute of Medical Sciences, Gwangju, South Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094906PMC
http://dx.doi.org/10.4161/cbt.9.12.11804DOI Listing
June 2010

The Hox genes and their roles in oncogenesis.

Nat Rev Cancer 2010 May 1;10(5):361-71. Epub 2010 Apr 1.

Nilay Shah and Saraswati Sukumar are at the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://www.nature.com/articles/nrc2826
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http://dx.doi.org/10.1038/nrc2826DOI Listing
May 2010

Clonal selection in tamoxifen resistance.

Cancer Biol Ther 2010 May;9(9):725-7

Breast Cancer Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.

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http://dx.doi.org/10.4161/cbt.9.9.11952DOI Listing
May 2010

MethySYBR, a novel quantitative PCR assay for the dual analysis of DNA methylation and CpG methylation density.

J Mol Diagn 2009 Sep;11(5):400-14

Breast Cancer Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans St., CRBI-143, Baltimore, MD 21231, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152515781060257
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http://dx.doi.org/10.2353/jmoldx.2009.080126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729837PMC
September 2009

Hypermethylated genes as biomarkers of cancer in women with pathologic nipple discharge.

Clin Cancer Res 2009 Jun 26;15(11):3802-11. Epub 2009 May 26.

Departments of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-1981DOI Listing
June 2009

PIK3CA somatic mutations in breast cancer: Mechanistic insights from Langevin dynamics simulations.

Proteins 2009 May;75(2):499-508

Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland 21218, USA.

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http://doi.wiley.com/10.1002/prot.22265
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http://dx.doi.org/10.1002/prot.22265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094910PMC
May 2009

Epigenomics and breast cancer.

Pharmacogenomics 2008 Dec;9(12):1879-902

Johns Hopkins University School of Medicine, 1650 Orleans Street, CRBI-143, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.2217/14622416.9.12.1879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633440PMC
December 2008

Quantitative promoter hypermethylation profiles of ductal carcinoma in situ in North American and Korean women: Potential applications for diagnosis.

Cancer Biol Ther 2008 Sep 4;7(9):1398-406. Epub 2008 Sep 4.

Breast Cancer Program, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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September 2008

Hoxb7 inhibits transgenic HER-2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis.

Cancer Res 2008 May 7;68(10):3637-44. Epub 2008 May 7.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715065PMC
May 2008

A PET rat model for assessing the effectiveness of new chemotherapies.

Cancer Biol Ther 2008 Apr;7(4):538-9

Department of Radiology and Radiological Sciences, The JohnsHopkins University School of Medicine, Baltimore, MD 21205, USA.

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April 2008