Sarah K Tasian

Sarah K Tasian

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Sarah K Tasian

Sarah K Tasian

Publications by authors named "Sarah K Tasian"

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Development and Clinical Validation of a Large Fusion Gene Panel for Pediatric Cancers.

J Mol Diagn 2019 Sep 27;21(5):873-883. Epub 2019 Jun 27.

Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15251578193006
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http://dx.doi.org/10.1016/j.jmoldx.2019.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734859PMC
September 2019

A parsimonious 3-gene signature predicts clinical outcomes in an acute myeloid leukemia multicohort study.

Blood Adv 2019 Apr;3(8):1330-1346

John van Geest Cancer Research Centre, College of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom.

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http://dx.doi.org/10.1182/bloodadvances.2018030726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482359PMC
April 2019

Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL.

Stem Cell Res 2018 08 5;31:157-160. Epub 2018 Jul 5.

Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, United States; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, United States. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.07.001DOI Listing
August 2018

Acute myeloid leukemia chimeric antigen receptor T-cell immunotherapy: how far up the road have we traveled?

Authors:
Sarah K Tasian

Ther Adv Hematol 2018 Jun 17;9(6):135-148. Epub 2018 May 17.

Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania and Abramson Cancer Center, 3501 Civic Center Boulevard, CTRB, 3010, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1177/2040620718774268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992809PMC
June 2018

Targeting Leukemia Stem Cells in the Bone Marrow Niche.

Biomedicines 2018 Feb 21;6(1). Epub 2018 Feb 21.

John van Geest Cancer Research Centre, Nottingham Trent University, Nottingham NG11 8NS, UK.

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http://dx.doi.org/10.3390/biomedicines6010022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874679PMC
February 2018

mTOR inhibition enhances efficacy of dasatinib in -rearranged Ph-like B-ALL.

Oncotarget 2018 Jan 6;9(5):6562-6571. Epub 2018 Jan 6.

Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, USA.

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http://dx.doi.org/10.18632/oncotarget.24020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814232PMC
January 2018

Philadelphia chromosome-like acute lymphoblastic leukemia.

Blood 2017 11 2;130(19):2064-2072. Epub 2017 Oct 2.

Department of Pediatrics, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1182/blood-2017-06-743252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680607PMC
November 2017

Targeting FLT3 Signaling in Childhood Acute Myeloid Leukemia.

Front Pediatr 2017 20;5:248. Epub 2017 Nov 20.

Children's Hospital of Philadelphia, Division of Oncology, Center for Childhood Cancer Research, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fped.2017.00248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702014PMC
November 2017

How is the Ph-like signature being incorporated into ALL therapy?

Best Pract Res Clin Haematol 2017 09 15;30(3):222-228. Epub 2017 Jun 15.

Department of Pediatrics and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15216926173001
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http://dx.doi.org/10.1016/j.beha.2017.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053910PMC
September 2017

Improved surfaceome coverage with a label-free nonaffinity-purified workflow.

Proteomics 2017 04 6;17(7). Epub 2017 Mar 6.

Protein and Proteomics Core Facility, The Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/pmic.201600344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518111PMC
April 2017

Genomic characterization of paediatric acute lymphoblastic leukaemia: an opportunity for precision medicine therapeutics.

Br J Haematol 2017 03 16;176(6):867-882. Epub 2016 Dec 16.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.14474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352516PMC
March 2017

Histology of Testicular Biopsies Obtained for Experimental Fertility Preservation Protocol in Boys with Cancer.

J Urol 2015 Nov 30;194(5):1420-4. Epub 2015 May 30.

Division of Urology, Department of Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Division of Urology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.juro.2015.04.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615387PMC
November 2015

Childhood acute lymphoblastic leukemia: Integrating genomics into therapy.

Cancer 2015 Oct 20;121(20):3577-90. Epub 2015 Jul 20.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/cncr.29573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592406PMC
October 2015

CD19-redirected chimeric antigen receptor-modified T cells: a promising immunotherapy for children and adults with B-cell acute lymphoblastic leukemia (ALL).

Ther Adv Hematol 2015 Oct;6(5):228-41

Division of Hematology/Oncology and Ben Towne Center for Childhood Cancer Research/Seattle Children's Research Institute, Seattle Children's Hospital, Seattle, WA, USA and University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.1177/2040620715588916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556967PMC
October 2015

Mixed Phenotype Acute Leukemia with Low Hypodiploidy in a Pediatric Patient.

J Pediatr Oncol 2015;3(1):24-28. Epub 2015 Mar 25.

Division of Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.14205/2309-3021.2015.03.01.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626005PMC
March 2015

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

N Engl J Med 2014 Sep;371(11):1005-15

From the Departments of Pathology (K.G.R., D.P.-T., Y.-L.Y., K. McCastlain, G.S., J.M., S.-C.C., J.C., N.S.-M., I.I., J.W., J.R.D., C.G.M.), Computational Biology and Bioinformatics (Y.L., J.B., M.R., E.H., P.G., P.N., G.W., X.C., J.Z.), Biostatistics (D.P., C.C.), Pharmaceutical Sciences (S.W.P., M.V.R., W.E.E.), and Oncology (C.-H.P., S.J.), the Pediatric Cancer Genome Project (Y.L., L.D., C.L., M.R., J.E., J.C., K.B., R.S.F., E.H., P.G., P.N., G.W., X.C., D.Y., B.V., H.M., M.V.R., W.E.E., E.M., R.K.W., J.R.D., J.Z., C.G.M.), and Cytogenetics Shared Resource (M.V.), St. Jude Children's Research Hospital, Memphis, TN; the University of New Mexico Cancer Center and School of Medicine, Albuquerque (R.C.H., I-M.C., C.L.W.); the Genome Institute at Washington University (L.D., C.L., R.S.F., E.M., R.K.W.), the Department of Genetics, Washington University School of Medicine (L.D., C.L., R.S.F., E.M., R.K.W.), and Siteman Cancer Center, Washington University (E.M., R.K.W.) - all in St. Louis; Epidemiology and Health Policy Research, College of Medicine, University of Florida, Gainesville (M.D.); the Research Institute at Nationwide Children's Hospital (S.R., A.S., J.M.G.-F.), the Department of Pathology, College of Medicine, Ohio State University (N.A.H.), and Ohio State University Comprehensive Cancer Center (G.M., C.D.B., K. Mrózek, J.K.) - all in Columbus, OH; the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas (N.J.W.), Scott and White Hospitals and Clinics and Texas A&M Health Science Center, Temple (G.G.), the University of Texas Health Science Center San Antonio, San Antonio (M.F.-J.), and the Departments of Leukemia and Stem Cell Transplantation, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston (S.M.K., M.K.) - all in Texas; Maine Children's Cancer Program, Scarborough (E.C.L.); New York University Cancer Institute, New York (W.L.C.), and the Department of Medicine (Oncology), Albert Einstein

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http://dx.doi.org/10.1056/NEJMoa1403088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191900PMC
September 2014

Molecular therapeutic approaches for pediatric acute myeloid leukemia.

Front Oncol 2014 18;4:55. Epub 2014 Mar 18.

Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania , Philadelphia, PA , USA.

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http://dx.doi.org/10.3389/fonc.2014.00055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957536PMC
June 2014

Targeting the PI3K/mTOR Pathway in Pediatric Hematologic Malignancies.

Front Oncol 2014 16;4:108. Epub 2014 May 16.

Division of Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine , Philadelphia, PA , USA.

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http://dx.doi.org/10.3389/fonc.2014.00108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032892PMC
June 2014

Development of anaplastic Wilms tumor and subsequent relapse in a child with diaphanospondylodysostosis.

J Pediatr Hematol Oncol 2012 Oct;34(7):548-51

Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of California, San Francisco School of Medicine, San Francisco, CA, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MPH.0b013e3182465b58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394881PMC
October 2012

Understanding the biology of CRLF2-overexpressing acute lymphoblastic leukemia.

Crit Rev Oncog 2011 ;16(1-2):13-24

Department of Pediatrics, Division of Pediatric Hemotology-Oncology, University of California San Francisco, San Francisco, CA 94143, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404310PMC
February 2012

Antigen loading of DCs with irradiated apoptotic tumor cells induces improved anti-tumor immunity compared to other approaches.

Cancer Immunol Immunother 2009 Aug 13;58(8):1257-64. Epub 2009 Jan 13.

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute/National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s00262-008-0638-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791794PMC
August 2009

Influenza-associated morbidity in children with cancer.

Pediatr Blood Cancer 2008 May;50(5):983-7

Department of Pediatrics, University of Washington and Children's Hospital & Regional Medical Center, Seattle, Washington 98105, USA.

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http://doi.wiley.com/10.1002/pbc.21472
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http://dx.doi.org/10.1002/pbc.21472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511372PMC
May 2008