Publications by authors named "Sarah Gale"

19Publications

Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment.

J Lipid Res 2020 03 27;61(3):403-412. Epub 2020 Jan 27.

Department of Medicine, Washington University School of Medicine, St. Louis, MO

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March 2020

19q13.12 microdeletion syndrome fibroblasts display abnormal storage of cholesterol and sphingolipids in the endo-lysosomal system.

Biochim Biophys Acta Mol Basis Dis 2018 06 24;1864(6 Pt A):2108-2118. Epub 2018 Mar 24.

Atlantic Research Center, Depts. of Pediatrics and Biochemistry & Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address:

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June 2018

snoRNA U17 regulates cellular cholesterol trafficking.

Cell Metab 2015 Jun 14;21(6):855-67. Epub 2015 May 14.

Diabetic Cardiovascular Disease Center and Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA. Electronic address:

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June 2015

Side-chain oxysterols modulate cholesterol accessibility through membrane remodeling.

Biochemistry 2014 May 1;53(18):3042-51. Epub 2014 May 1.

Diabetic Cardiovascular Disease Center, Washington University School of Medicine , St. Louis, Missouri 63110, United States.

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May 2014

Box C/D small nucleolar RNA (snoRNA) U60 regulates intracellular cholesterol trafficking.

J Biol Chem 2013 Dec 30;288(50):35703-13. Epub 2013 Oct 30.

From the Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St. Louis, Missouri 63110.

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December 2013

Tumoral calcinosis: a dental literature review and case report.

Dent Update 2012 Jul-Aug;39(6):416-8, 421

Birmingham Dental Hospital, Birmingham B4 6NN, UK.

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September 2012

Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease.

Sci Transl Med 2010 Nov;2(56):56ra81

Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.

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November 2010

Niemann-Pick type C1 I1061T mutant encodes a functional protein that is selected for endoplasmic reticulum-associated degradation due to protein misfolding.

J Biol Chem 2008 Mar 23;283(13):8229-36. Epub 2008 Jan 23.

Center for Cardiovascular Research, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA.

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March 2008

Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death.

J Lipid Res 2006 Dec 7;47(12):2726-37. Epub 2006 Sep 7.

Center for Cardiovascular Research, Division of Cardiology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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December 2006

Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease.

Proc Natl Acad Sci U S A 2006 Sep 29;103(37):13807-12. Epub 2006 Aug 29.

Center for Cardiovascular Research, Department of Internal Medicine, and Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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September 2006

A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation.

J Biol Chem 2006 Apr 22;281(16):11082-9. Epub 2006 Feb 22.

Center for Cardiovascular Research and Department of Internal Medicine, School of Medicine, Washington University, St. Louis, Missouri 63110-1010, USA.

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April 2006

The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol.

J Biol Chem 2005 Aug 20;280(31):28581-90. Epub 2005 May 20.

Center for Cardiovascular Research, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110-1010, USA.

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August 2005

Day 3 and day 5 morphological predictors of embryo viability.

Reprod Biomed Online 2003 Apr-May;6(3):323-31

Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, ASB 1+3, Room 082, Boston, MA 02115, USA.

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December 2003