Publications by authors named "Sarah Blagden"

54Publications

Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells.

Dev Cell 2020 Nov;55(3):298-313.e10

Centre for Cancer Cell and Molecular Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2020.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660134PMC
November 2020

NUC-1031, use of ProTide technology to circumvent gemcitabine resistance: current status in clinical trials.

Med Oncol 2020 Jun 11;37(7):61. Epub 2020 Jun 11.

Division of Cancer Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/s12032-020-01386-6DOI Listing
June 2020

Controversies around the function of LARP1.

RNA Biol 2020 Apr 1:1-11. Epub 2020 Apr 1.

Department of Oncology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1080/15476286.2020.1733787DOI Listing
April 2020

Meningococcal vaccination in primary care amongst adolescents in North West England: an ecological study investigating associations with general practice characteristics.

J Public Health (Oxf) 2019 03;41(1):149-157

Division of Health Research, Furness Building, Lancaster University, Lancaster, UK.

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http://dx.doi.org/10.1093/pubmed/fdy010DOI Listing
March 2019

Uptake of a new meningitis vaccination programme amongst first-year undergraduate students in the United Kingdom: A cross-sectional study.

PLoS One 2017 2;12(8):e0181817. Epub 2017 Aug 2.

Department of Public Health and Policy, Institute of Psychology Health and Society, University of Liverpool, Liverpool, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181817PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540503PMC
October 2017

Ancient and modern: hints of a core post-transcriptional network driving chemotherapy resistance in ovarian cancer.

Wiley Interdiscip Rev RNA 2018 01 1;9(1). Epub 2017 Aug 1.

Department of Oncology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/wrna.1432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763387PMC
January 2018

The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer.

Nucleic Acids Res 2016 Feb 29;44(3):1227-46. Epub 2015 Dec 29.

Ovarian Cancer Action Research Centre, Institute of Reproductive and Developmental Biology, Imperial College, London W12 0HS, UK Department of Oncology, University of Oxford, Old Road, Oxford OX3 7LE, UK

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http://dx.doi.org/10.1093/nar/gkv1515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756840PMC
February 2016

The La-Related Proteins, a Family with Connections to Cancer.

Biomolecules 2015 Oct 16;5(4):2701-22. Epub 2015 Oct 16.

Ovarian Cancer Research Centre, Institute for Reproductive and Developmental Biology, Imperial College, Du Cane Road, London W12 0HS, UK.

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http://dx.doi.org/10.3390/biom5042701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693254PMC
October 2015

A Comparative Study of Quality of Life in Persons With Irritable Bowel Syndrome and Inflammatory Bowel Disease.

Gastroenterol Nurs 2015 Jul-Aug;38(4):268-78

Sarah Blagden, MBChB, BMedSc, is Foundation Year Two Doctor, Sandwell and West Birimingham Hospitals NHS Foundation Trust, West Bromwich, United Kingdom. Thomas Kingstone, MSc, is PhD Student, Primary Care and Health Sciences, University of Keele, Staffordshire, United Kingdom. Andrew Soundy, PhD, is Lecturer in Physiotherapy, School of Sport, Exercise and Rehabilitation, University of Birmingham, Edgbaston, Birmingham, United Kingdom. Rhonda Lee, MBBS, MPh, is Holistic Physician, C/O Freshwinds, Prospect Hall, Selly Oak, Birmingham, United Kingdom. Sukhdev Singh, MD, FRCP, is Consultant Gastroenterologist, Good Hope Hospital, Rectory Road, Sutton Coldfield, West Midlands, United Kingdom. Lesley Roberts, PhD, is Professor of Medical Education and Pro Dean Education, Warwick Medical School, University of Warwick, Coventry, United Kingdom.

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https://insights.ovid.com/crossref?an=00001610-201507000-000
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http://dx.doi.org/10.1097/SGA.0000000000000124DOI Listing
January 2017

Harnessing Pandemonium: The Clinical Implications of Tumor Heterogeneity in Ovarian Cancer.

Authors:
Sarah P Blagden

Front Oncol 2015 30;5:149. Epub 2015 Jun 30.

Department of Oncology, Churchill Hospital, University of Oxford , Oxford , UK.

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http://dx.doi.org/10.3389/fonc.2015.00149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485078PMC
July 2015

The next steps in improving the outcomes of advanced ovarian cancer.

Womens Health (Lond) 2015 Jun;11(3):355-67

Department of Medical Oncology, Hammersmith Hospital, Imperial College NHS, London, UK.

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http://dx.doi.org/10.2217/whe.15.6DOI Listing
June 2015

Risk of Ovarian Cancer Relapse score: a prognostic algorithm to predict relapse following treatment for advanced ovarian cancer.

Int J Gynecol Cancer 2015 Mar;25(3):416-22

*Imperial College Healthcare NHS Trust, Garry Weston Cancer Centre, and †Ovarian Cancer Action Research Centre, Hammersmith Hospital; and ‡Division of Experimental Medicine, Imperial College London, Hammersmith Campus, London, United Kingdom.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/IGC.0000000000000361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340599PMC
March 2015

Application of ProTide technology to gemcitabine: a successful approach to overcome the key cancer resistance mechanisms leads to a new agent (NUC-1031) in clinical development.

J Med Chem 2014 Feb 14;57(4):1531-42. Epub 2014 Feb 14.

Cardiff School of Pharmacy & Pharmaceutical Sciences, Cardiff University , King Edward VII Avenue, Cardiff CF10 3NB, United Kingdom.

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http://dx.doi.org/10.1021/jm401853aDOI Listing
February 2014

The perfect arrangement.

Authors:
Sarah P Blagden

J Clin Oncol 2014 Feb 21;32(6):601-2. Epub 2014 Jan 21.

From the Imperial College Healthcare NHS Trust, Hammersmith Campus, London, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2013.54.3405DOI Listing
February 2014

Developing an objective marker to optimize patient selection and predict survival benefit in early-phase cancer trials.

Cancer 2014 Jan 8;120(2):262-70. Epub 2013 Oct 8.

Department of Experimental Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.

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http://doi.wiley.com/10.1002/cncr.28381
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http://dx.doi.org/10.1002/cncr.28381DOI Listing
January 2014

Feasibility of trials in ovarian cancer by line of therapy and platinum sensitivity.

Int J Gynecol Cancer 2013 Mar;23(3):481-7

Ovarian Cancer Action Research Centre, Division of Oncology, Hammersmith Hospital Campus, Imperial College London, London, UK.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/IGC.0b013e31828702f6DOI Listing
March 2013

A study to evaluate the cause of bone demineralization in gynecological cancer survivors.

Oncologist 2013 30;18(4):423-9. Epub 2013 Jan 30.

Division of Experimental Medicine and Toxicology, Department of Medicine, Imperial College, London, Hammersmith Hospital, London, Uk.

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http://dx.doi.org/10.1634/theoncologist.2012-0416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639529PMC
December 2013

Cerebral sinus thrombosis and leptomeningeal carcinomatosis in a patient with ovarian cancer.

J Clin Oncol 2012 Jan 12;30(2):e19-20. Epub 2011 Dec 12.

Department of Oncology, Hammersmith Hospital, Imperial College, Du Cane Rd, London W12 0NN, United Kingdom.

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http://jco.ascopubs.org/content/30/2/e19.full.pdf
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2011.38.1426
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http://dx.doi.org/10.1200/JCO.2011.38.1426DOI Listing
January 2012

A study of symptoms described by ovarian cancer survivors.

Gynecol Oncol 2012 Apr 9;125(1):59-64. Epub 2011 Dec 9.

Department of Medicine, Imperial College, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00908258110139
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http://dx.doi.org/10.1016/j.ygyno.2011.12.421DOI Listing
April 2012

The biological and therapeutic relevance of mRNA translation in cancer.

Nat Rev Clin Oncol 2011 May 1;8(5):280-91. Epub 2011 Mar 1.

Department of Oncology, Imperial College Hammersmith Campus, Du Cane Road, London W12 0HS, UK. s.blagden@ imperial.ac.uk

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http://dx.doi.org/10.1038/nrclinonc.2011.16DOI Listing
May 2011

The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration.

Nucleic Acids Res 2010 Sep 29;38(16):5542-53. Epub 2010 Apr 29.

Department of Molecular Oncology, Imperial College, Hammersmith Campus, Du Cane Road, London W12 0HS, UK.

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http://dx.doi.org/10.1093/nar/gkq294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938220PMC
September 2010

Drosophila Larp associates with poly(A)-binding protein and is required for male fertility and syncytial embryo development.

Dev Biol 2009 Oct 22;334(1):186-97. Epub 2009 Jul 22.

Cancer Research UK Cell Cycle Genetics Group, University of Cambridge, Department of Genetics, Cambridge CB2 3EH, UK.

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http://dx.doi.org/10.1016/j.ydbio.2009.07.016DOI Listing
October 2009

Promising molecular targets in ovarian cancer.

Curr Opin Oncol 2009 Sep;21(5):412-9

Ovarian Cancer Action Research Centre, Imperial College London Hammersmith Campus, London, UK.

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https://insights.ovid.com/crossref?an=00001622-200909000-000
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http://dx.doi.org/10.1097/CCO.0b013e32832eab1fDOI Listing
September 2009

A phase I dose escalation study of the pharmacokinetics and tolerability of ZK 304709, an oral multi-targeted growth inhibitor (MTGI), in patients with advanced solid tumours.

Cancer Chemother Pharmacol 2009 Jul 12;64(2):425-9. Epub 2009 Mar 12.

Department of Oncology, University of Leicester, Leicester Royal Infirmary, Leicester, LE1 5WW, England, UK.

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http://dx.doi.org/10.1007/s00280-009-0968-yDOI Listing
July 2009

Future directions in the management of epithelial ovarian cancer.

Future Oncol 2008 Jun;4(3):403-11

Imperial College London, Ovarian Cancer Action Research Center, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.

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https://www.futuremedicine.com/doi/10.2217/14796694.4.3.403
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http://dx.doi.org/10.2217/14796694.4.3.403DOI Listing
June 2008

Targeting cell cycle kinases and kinesins in anticancer drug development.

Expert Opin Drug Discov 2007 Apr;2(4):539-60

Drug Development Unit, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey, SM2 5PT, UK.

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http://dx.doi.org/10.1517/17460441.2.4.539DOI Listing
April 2007

Making sense of antisense.

Eur J Cancer 2005 Dec 9;41(18):2812-8. Epub 2005 Nov 9.

Centre for Cancer Therapeutics, Institute of Cancer Research, Royal Marsden Hospital, Sutton, Surrey SM2 5PT, London, United Kingdom.

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http://dx.doi.org/10.1016/j.ejca.2005.06.029DOI Listing
December 2005

Docetaxel in the management of ovarian cancer.

Expert Rev Anticancer Ther 2005 Apr;5(2):203-14

Royal Marsden Hospital Downs Road, Sutton, Surrey SM2 5PT, UK.

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http://dx.doi.org/10.1586/14737140.5.2.203DOI Listing
April 2005

Polar expeditions--provisioning the centrosome for mitosis.

Nat Cell Biol 2003 Jun;5(6):505-11

Cancer Research UK Cell Cycle Genetics Research Group, University of Cambridge, Department of Genetics, Downing Street, Cambridge, CB2 3EH, UK.

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http://dx.doi.org/10.1038/ncb0603-505DOI Listing
June 2003