Sara Imarisio

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Sara Imarisio

Publications by authors named "Sara Imarisio"

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26Publications

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Polyglutamine tracts regulate autophagy.

Autophagy 2017 Sep 19;13(9):1613-1614. Epub 2017 Jul 19.

a Department of Medical Genetics, Cambridge Institute for Medical Research (CIMR) , University of Cambridge , Cambridge , UK.

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September 2017

Polyglutamine tracts regulate beclin 1-dependent autophagy.

Nature 2017 05 26;545(7652):108-111. Epub 2017 Apr 26.

Department of Medical Genetics, Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge, UK.

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May 2017

CCT complex restricts neuropathogenic protein aggregation via autophagy.

Nat Commun 2016 Dec 8;7:13821. Epub 2016 Dec 8.

Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.

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December 2016

PICALM modulates autophagy activity and tau accumulation.

Nat Commun 2014 Sep 22;5:4998. Epub 2014 Sep 22.

Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.

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September 2014

Modeling serpin conformational diseases in Drosophila melanogaster.

Methods Enzymol 2011 ;499:227-58

Department of Genetics, University of Cambridge, Cambridge, United Kingdom.

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October 2011

Complex inhibitory effects of nitric oxide on autophagy.

Mol Cell 2011 Jul;43(1):19-32

Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, UK.

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July 2011

Lysosomal positioning coordinates cellular nutrient responses.

Nat Cell Biol 2011 Apr 13;13(4):453-60. Epub 2011 Mar 13.

Department of Medical Genetics, Cambridge Institute for Medical Genetics, Wellcome Trust/MRC Building, Hills Road, Cambridge, CB2 0XY, UK.

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April 2011

Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy.

Hum Mol Genet 2010 Dec 9;19(23):4573-86. Epub 2010 Sep 9.

Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.

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December 2010

Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

Hum Mol Genet 2010 Sep 21;19(17):3413-29. Epub 2010 Jun 21.

Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

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September 2010

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

J Cell Biol 2010 Sep;190(6):1023-37

Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, England, UK.

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September 2010

Huntington's disease: from pathology and genetics to potential therapies.

Biochem J 2008 Jun;412(2):191-209

Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

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June 2008

Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease.

J Cell Sci 2008 May 22;121(Pt 10):1649-60. Epub 2008 Apr 22.

Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, UK.

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May 2008

A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.

Hum Mol Genet 2008 Jan 6;17(2):170-8. Epub 2007 Oct 6.

Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

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January 2008

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

Nat Chem Biol 2007 Jun 7;3(6):331-8. Epub 2007 May 7.

Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.

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June 2007

The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase.

J Cell Sci 2007 Jun 8;120(Pt 11):1859-67. Epub 2007 May 8.

Molecular Biotechnology Center, Department of Genetics, Biology and Biochemistry, University of Turin, Italy.

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June 2007

Dyneins, autophagy, aggregation and neurodegeneration.

Autophagy 2005 Oct-Dec;1(3):177-8. Epub 2005 Oct 21.

Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome/MRC Building, Addenbrooke's Hospital, Cambridge, UK.

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January 2007

Lithium induces autophagy by inhibiting inositol monophosphatase.

J Cell Biol 2005 Sep;170(7):1101-11

Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge CB2 2XY, England, UK.

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September 2005

Dynein mutations impair autophagic clearance of aggregate-prone proteins.

Nat Genet 2005 Jul 26;37(7):771-6. Epub 2005 Jun 26.

Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2XY, UK.

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July 2005

PAkt, cyclin D1 and p27/Kip.1 in glioblastomas with and without EGFR amplification and PTEN mutation.

Anticancer Res 2004 Sep-Oct;24(5A):2643-7

Department of Neuroscience, University of Turin, Via Cherasco, 15 and Turin, Italy.

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December 2004

Drosophila citron kinase is required for the final steps of cytokinesis.

Mol Biol Cell 2004 Nov 15;15(11):5053-63. Epub 2004 Sep 15.

Istituto di Biologia e Patologia Molecolari del Consiglio Nazionale Delle Ricerche, Dipartimento di Genetica e Biologia Molecolare, Universitá La Sapienza, 00185 Rome, Italy.

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November 2004

Citron-N is a neuronal Rho-associated protein involved in Golgi organization through actin cytoskeleton regulation.

Nat Cell Biol 2003 Dec 2;5(12):1071-8. Epub 2003 Nov 2.

Dipartimento di Genetica, Biologia e Biochimica, Università Degli Studi di Torino Via Santena, 5 bis, Torino, Italy.

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December 2003

Role of citron kinase in dendritic morphogenesis of cortical neurons.

Brain Res Bull 2003 May;60(4):319-27

Department of Genetics, Biology and Biochemistry, University of Torino, Via Santena 5 bis, 10126, Torino, Italy.

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May 2003

Citron kinase is a cell cycle-dependent, nuclear protein required for G2/M transition of hepatocytes.

J Biol Chem 2003 Jan 30;278(4):2541-8. Epub 2002 Oct 30.

Department of Cell and Molecular Physiology, University of North Carolina School of Medicine, Chapel Hill, 27599, USA.

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January 2003

Essential role of citron kinase in cytokinesis of spermatogenic precursors.

J Cell Sci 2002 Dec;115(Pt 24):4819-26

Department of Genetics, Biology and Biochemistry, Via Santena 5 bis, Torino, Italy.

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December 2002