Publications

CCT complex restricts neuropathogenic protein aggregation via autophagy.
Nat Commun 2016 Dec 8;7:13821. Epub 2016 Dec 8.
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.


PICALM modulates autophagy activity and tau accumulation.
Nat Commun 2014 Sep 22;5:4998. Epub 2014 Sep 22.
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.

Complex inhibitory effects of nitric oxide on autophagy.
Mol Cell 2011 Jul;43(1):19-32
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, UK.

Lysosomal positioning coordinates cellular nutrient responses.
Nat Cell Biol 2011 Apr 13;13(4):453-60. Epub 2011 Mar 13.
Department of Medical Genetics, Cambridge Institute for Medical Genetics, Wellcome Trust/MRC Building, Hills Road, Cambridge, CB2 0XY, UK.

Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.
Hum Mol Genet 2010 Sep 21;19(17):3413-29. Epub 2010 Jun 21.
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.
J Cell Biol 2010 Sep;190(6):1023-37
Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, England, UK.

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
Nat Chem Biol 2007 Jun 7;3(6):331-8. Epub 2007 May 7.
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.

Citron-N is a neuronal Rho-associated protein involved in Golgi organization through actin cytoskeleton regulation.
Nat Cell Biol 2003 Dec 2;5(12):1071-8. Epub 2003 Nov 2.
Dipartimento di Genetica, Biologia e Biochimica, Università Degli Studi di Torino Via Santena, 5 bis, Torino, Italy.

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