Biography

Primary Affiliation: Massachusetts General Hospital/Harvard Medical School - Boston, MASSACHUSETTS , United States

Specialties: Otolaryngology-Head and Neck Surgery

Research Interests: HPV-associated Head and Neck Cancers; Immunotherapy for Head and Neck Cancers

Education
  • 2007
    Residency Johns Hopkins Hospital
  • 2003
    Internship Johns Hopkins Hospital
  • 2002
    MD/PhD Johns Hopkins School of Medicine
 

Publications

HLA class I antigen processing machinery (APM) component expression and PD-1:PD-L1 pathway activation in HIV-infected head and neck cancers.
Oral Oncol 2018 Feb 28;77:92-97. Epub 2017 Dec 28.
Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, PA, United States. Electronic address:





Oral human papillomavirus (HPV) infection in HPV-positive patients with oropharyngeal cancer and their partners.
J Clin Oncol 2014 Aug 28;32(23):2408-15. Epub 2014 Apr 28.
Gypsyamber D'Souza, Shirani Rajan, and Jennifer Gerber, Johns Hopkins Bloomberg School of Public Health; Sara I. Pai, Johns Hopkins Medical Institutions, Baltimore, MD; Neil D. Gross, Oregon Health and Science University, Portland, OR; Robert Haddad, Dana-Farber Cancer Institute, Boston, MA; Karen S. Anderson, Arizona State University, Tempe, AZ; Maura L. Gillison, Ohio State University Comprehensive Cancer Center, Columbus, OH; and Marshall R. Posner, Icahn School of Medicine at Mount Sinai, New York, NY.

Human papillomavirus status of head and neck cancer as determined in cytologic specimens using the hybrid-capture 2 assay.
Oral Oncol 2014 Jun 12;50(6):600-4. Epub 2014 Mar 12.
Department of Otolaryngology - Head and Neck Surgery, The Johns Hopkins School of Medicine, Baltimore, MD 21287, United States; Department of Oncology, The Johns Hopkins School of Medicine, Baltimore, MD 21287, United States. Electronic address:

Epidemiology of head and neck squamous cell cancer among HIV-infected patients.
J Acquir Immune Defic Syndr 2014 Apr;65(5):603-10
*Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; †Department of Otolaryngology/Head and Neck Surgery, University of Michigan, Ann Arbor, MI; ‡Department of Head and Neck Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX; §Department of Internal Medicine, Emory University School of Medicine, Atlanta, GA; ‖Department of Radiation Oncology, Mount Sinai Medical Center, New York, NY; ¶Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI; #Department of Otolaryngology/Head and Neck Surgery, Johns Hopkins University, Baltimore, MD; **Cancer Biology Program, University of Michigan, Ann Arbor, MI; ††Department of Biostatistics, University of Texas M. D. Anderson Cancer Center, Houston, TX; §§Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA; and ‖‖Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Enhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumors.
Clin Cancer Res 2014 Feb 3;20(3):644-57. Epub 2013 Dec 3.
Authors' Affiliations: Departments of Pathology, Obstetrics and Gynecology, Molecular Microbiology and Immunology, Oncology, and Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions; Department of Biostatistics and Bioinformatics, Sidney Kimmel Cancer Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; Departments of Obstetrics and Gynecology, Kunming Medical University, Yunnan, China; Nephrology, Chang-Gung Memorial Hospital, Gueishan; Department of Obstetrics and Gynecology, Tri-Service General Hospital, Taipei, Taiwan; and Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama.

The relationship between chronic lymphocytic thyroiditis and central neck lymph node metastasis in North American patients with papillary thyroid carcinoma.
Surgery 2013 Dec;154(6):1272-80; discussion 1280-2
Division of Head and Neck Endocrine Surgery, Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.





Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine.
Cancer Immunol Immunother 2013 Jan 4;62(1):171-82. Epub 2012 Aug 4.
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.




Incidence of malignancy in thyroid nodules determined to be follicular lesions of undetermined significance on fine-needle aspiration.
World J Surg 2012 Jan;36(1):69-74
Department of Oncologic Surgery/Head and Neck Surgery CEPON, R. Presidente Coutinho, 579, Sala 304, Florianopolis, SC 88015-231, Brazil.


Profile of patients with completion thyroidectomy and assessment of their suitability for outpatient surgery.
Otolaryngol Head Neck Surg 2011 Nov 22;145(5):727-31. Epub 2011 Aug 22.
Division of Thyroid and Parathyroid Surgery, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA.


Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma.
Int J Oncol 2011 Aug 23;39(2):337-44. Epub 2011 May 23.
Department of Otolaryngology, Head and Neck Surgery, The Johns Hopkins University, 1550 Orleans Street, CRBII (Rm 574), Baltimore, MD 21231, USA.

Selective versus comprehensive neck dissection after chemoradiation for advanced oropharyngeal squamous cell carcinoma.
Otolaryngol Head Neck Surg 2009 Dec;141(6):737-42
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, and the Johns Hopkins Head and Neck Surgery, Baltimore, MD 21231, USA.




Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe.
Vaccine 2003 Sep;21(25-26):4036-42
Department of Obstetrics and Gynecology, The Johns Hopkins Medical Institution, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.


Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma.
Cancer Epidemiol Biomarkers Prev 2002 Jan;11(1):3-6
Department of Otolaryngology-Head and Neck Surgery, Head and Neck Cancer Research Division, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA.

The role of antagonists of the PD-1:PD-L1/PD-L2 axis in head and neck cancer treatment.
Oral Oncol 2016 10 5;61:152-8. Epub 2016 Aug 5.
Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, United States; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, United States.



Sequential cisplatin therapy and vaccination with HPV16 E6E7L2 fusion protein in saponin adjuvant GPI-0100 for the treatment of a model HPV16+ cancer.
PLoS One 2015 5;10(1):e116389. Epub 2015 Jan 5.
Department of Pathology, The Johns Hopkins University, Baltimore, Maryland, United States of America; Department of Oncology, The Johns Hopkins University, Baltimore, Maryland, United States of America; Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, Maryland, United States of America.

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