Publications by authors named "Santiago G Lago"

11Publications

Functional patient-derived cellular models for neuropsychiatric drug discovery.

Authors:
Santiago G Lago Jakub Tomasik Sabine Bahn

Transl Psychiatry 2021 Feb 17;11(1):128. Epub 2021 Feb 17.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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February 2021

A machine learning algorithm to differentiate bipolar disorder from major depressive disorder using an online mental health questionnaire and blood biomarker data.

Authors:
Jakub Tomasik Sung Yeon Sarah Han Giles Barton-Owen Dan-Mircea Mirea Nayra A Martin-Key Nitin Rustogi Santiago G Lago Tony Olmert Jason D Cooper Sureyya Ozcan Pawel Eljasz Grégoire Thomas Robin Tuytten Tim Metcalfe Thea S Schei Lynn P Farrag Lauren V Friend Emily Bell Dan Cowell Sabine Bahn

Transl Psychiatry 2021 01 12;11(1):41. Epub 2021 Jan 12.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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January 2021

Exploring cellular markers of metabolic syndrome in peripheral blood mononuclear cells across the neuropsychiatric spectrum.

Authors:
Santiago G Lago Jakub Tomasik Geertje F van Rees Marina Rubey Emiliano Gonzalez-Vioque Jordan M Ramsey Frieder Haenisch Jantine A Broek Javier Vázquez-Bourgon Sergi Papiol Paula Suarez-Pinilla Tillmann Ruland Bonnie Auyeug Olya Mikova Nikolett Kabacs Volker Arolt Simon Baron-Cohen Benedicto Crespo-Facorro Sabine Bahn

Brain Behav Immun 2021 Jan 6;91:673-682. Epub 2020 Sep 6.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom. Electronic address:

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January 2021

Diagnostic prediction model development using data from dried blood spot proteomics and a digital mental health assessment to identify major depressive disorder among individuals presenting with low mood.

Authors:
Sung Yeon Sarah Han Jakub Tomasik Nitin Rustogi Santiago G Lago Giles Barton-Owen Pawel Eljasz Jason D Cooper Sureyya Ozcan Tony Olmert Lynn P Farrag Lauren V Friend Emily Bell Dan Cowell Grégoire Thomas Robin Tuytten Sabine Bahn

Brain Behav Immun 2020 11 27;90:184-195. Epub 2020 Aug 27.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Psyomics Ltd., Cambridge, UK. Electronic address:

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November 2020

Drug discovery for psychiatric disorders using high-content single-cell screening of signaling network responses ex vivo.

Authors:
Santiago G Lago Jakub Tomasik Geertje F van Rees Hannah Steeb David A Cox Nitin Rustogi Jordan M Ramsey Joshua A Bishop Tracey Petryshen Stephen J Haggarty Javier Vázquez-Bourgon Sergi Papiol Paula Suarez-Pinilla Benedicto Crespo-Facorro Nico J van Beveren Sabine Bahn

Sci Adv 2019 05 8;5(5):eaau9093. Epub 2019 May 8.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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May 2019

Association of Insulin Resistance With Schizophrenia Polygenic Risk Score and Response to Antipsychotic Treatment.

Authors:
Jakub Tomasik Santiago G Lago Javier Vázquez-Bourgon Sergi Papiol Paula Suárez-Pinilla Benedicto Crespo-Facorro Sabine Bahn

JAMA Psychiatry 2019 08;76(8):864-867

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, England.

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August 2019

Exploring the neuropsychiatric spectrum using high-content functional analysis of single-cell signaling networks.

Authors:
Santiago G Lago Jakub Tomasik Geertje F van Rees Jordan M Ramsey Frieder Haenisch Jason D Cooper Jantine A Broek Paula Suarez-Pinilla Tillmann Ruland Bonnie Auyeug Olya Mikova Nikolett Kabacs Volker Arolt Simon Baron-Cohen Benedicto Crespo-Facorro Sabine Bahn

Mol Psychiatry 2020 10 23;25(10):2355-2372. Epub 2018 Jul 23.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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October 2020

Clinical Trials and Therapeutic Rationale for Drug Repurposing in Schizophrenia.

Authors:
Santiago G Lago Sabine Bahn

ACS Chem Neurosci 2019 01 18;10(1):58-78. Epub 2018 Jul 18.

Department of Chemical Engineering and Biotechnology , University of Cambridge , Cambridge CB3 0AS , U.K.

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January 2019

Towards reproducible MRM based biomarker discovery using dried blood spots.

Authors:
Sureyya Ozcan Jason D Cooper Santiago G Lago Diarmuid Kenny Nitin Rustogi Pawel Stocki Sabine Bahn

Sci Rep 2017 03 27;7:45178. Epub 2017 Mar 27.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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March 2017

Pretreatment levels of the fatty acid handling proteins H-FABP and CD36 predict response to olanzapine in recent-onset schizophrenia patients.

Authors:
Jakub Tomasik Emanuel Schwarz Santiago G Lago Matthias Rothermundt F Markus Leweke Nico J M van Beveren Paul C Guest Hassan Rahmoune Johann Steiner Sabine Bahn

Brain Behav Immun 2016 Feb 2;52:178-186. Epub 2015 Nov 2.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Department of Neuroscience, Erasmus Medical Centre, Rotterdam, The Netherlands. Electronic address:

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February 2016

Technological advances for deciphering the complexity of psychiatric disorders: merging proteomics with cell biology.

Authors:
Hendrik Wesseling Paul C Guest Santiago G Lago Sabine Bahn

Int J Neuropsychopharmacol 2014 Aug 14;17(8):1327-41. Epub 2014 Feb 14.

Department of Chemical Engineering and Biotechnology,University of Cambridge,Cambridge CB2 1QT,UK.

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August 2014