Sanjeev Shukla

Sanjeev Shukla

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Genetic Changes of P and Kras in Gallbladder Carcinoma in Kumaon Region of Uttarakhand.

J Gastrointest Cancer 2019 Aug 9. Epub 2019 Aug 9.

Department of Pathology, Government Medical College, Haldwani, Nainital, Uttarakhand, 263139, India.

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http://dx.doi.org/10.1007/s12029-019-00283-0DOI Listing
August 2019

Enhanced adsorption performance of oxidised coconut coir for removal of Cd(II) ions by multi-column arrangement in series.

Environ Sci Pollut Res Int 2019 Jul 27. Epub 2019 Jul 27.

Department of Fibres and Textile Processing Technology, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga, Mumbai, 400019, India.

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http://dx.doi.org/10.1007/s11356-019-05995-1DOI Listing
July 2019

Histopathological Examination of Gallbladder Specimens in Kumaon Region of Uttarakhand.

J Gastrointest Cancer 2019 Mar 8. Epub 2019 Mar 8.

Department of Surgery, Government Medical College, Haldwani, Nainital, Uttarakhand, 263139, India.

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http://dx.doi.org/10.1007/s12029-018-00188-4DOI Listing
March 2019

Differentially Expressed Genes and Molecular Pathways in an Autochthonous Mouse Prostate Cancer Model.

Front Genet 2019 26;10:235. Epub 2019 Mar 26.

Department of Urology, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.

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http://dx.doi.org/10.3389/fgene.2019.00235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445055PMC
March 2019

Complex Systems Biology Approach in Connecting PI3K-Akt and NF-κB Pathways in Prostate Cancer.

Cells 2019 02 26;8(3). Epub 2019 Feb 26.

Department of Urology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.3390/cells8030201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468646PMC
February 2019

Synthesis of isatin based N-alkylated 3-β-C-glycoconjugated-oxopropylidene oxindoles as potent antiplasmodial agents.

Eur J Med Chem 2019 Jan 11;162:448-454. Epub 2018 Nov 11.

Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, 226031, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi, 110001, India. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.11.008DOI Listing
January 2019

Congenital Absence of Unilateral Internal Carotid Artery with an Intracerebral Aneurysm.

Asian J Neurosurg 2018 Jul-Sep;13(3):774-776

Department of Radiodiagnosis, Government Medical College and Associated Group of Hospitals, Kota, Rajasthan, India.

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http://dx.doi.org/10.4103/ajns.AJNS_312_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159071PMC
October 2018

Diosmetin suppresses human prostate cancer cell proliferation through the induction of apoptosis and cell cycle arrest.

Int J Oncol 2018 Aug 16;53(2):835-843. Epub 2018 May 16.

Department of Urology, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA.

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http://www.spandidos-publications.com/10.3892/ijo.2018.4407
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http://dx.doi.org/10.3892/ijo.2018.4407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017185PMC
August 2018

Acquisition of tumorigenic potential and therapeutic resistance in CD133+ subpopulation of prostate cancer cells exhibiting stem-cell like characteristics.

Cancer Lett 2018 08 15;430:25-33. Epub 2018 May 15.

Department of Urology, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA; The Urology Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA; Department of Urology, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, 44106, USA; Department of Nutrition, Case Western Reserve University, Cleveland, OH, 44106, USA; Division of General Medical Sciences, Case Comprehensive Cancer Center, Cleveland, OH, 44106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.05.014DOI Listing
August 2018

PAK2-c-Myc-PKM2 axis plays an essential role in head and neck oncogenesis via regulating Warburg effect.

Cell Death Dis 2018 08 1;9(8):825. Epub 2018 Aug 1.

Epigenetics and RNA Processing Lab, Department of Biological Sciences, Indian Institute of Science Education and Research, Bhopal, Madhya Pradesh, 462066, India.

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http://www.nature.com/articles/s41419-018-0887-0
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http://dx.doi.org/10.1038/s41419-018-0887-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070504PMC
August 2018

Synthesis and antiplasmodial activity of glyco-conjugate hybrids of phenylhydrazono-indolinones and glycosylated 1,2,3-triazolyl-methyl-indoline-2,3-diones.

Eur J Med Chem 2018 Jul 19;155:764-771. Epub 2018 Jun 19.

Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110001, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234183053
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http://dx.doi.org/10.1016/j.ejmech.2018.06.042DOI Listing
July 2018

Synthesis and antiplasmodial activity of purine-based -nucleoside analogues.

Medchemcomm 2018 Jul 29;9(7):1232-1238. Epub 2018 May 29.

Medicinal and Process Chemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India . Email: ; Tel: +9415004443.

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http://dx.doi.org/10.1039/c8md00098kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071838PMC
July 2018

Single-site labeling of lysine in proteins through a metal-free multicomponent approach.

Chem Commun (Camb) 2018 Jun;54(53):7302-7305

Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhauri, Bhopal, MP 462 066, India.

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http://dx.doi.org/10.1039/c8cc03311kDOI Listing
June 2018

Staging, Treatment, and Future Approaches of Gallbladder Carcinoma.

J Gastrointest Cancer 2018 Mar;49(1):9-15

Department of Pathology, Government Medical College, Haldwani, Nainital, U.K., India.

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http://dx.doi.org/10.1007/s12029-017-0036-5DOI Listing
March 2018

Prostate cancer susceptibility and growth linked to Y chromosome genes.

Front Biosci (Elite Ed) 2018 03 1;10:423-436. Epub 2018 Mar 1.

Department of Urology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH, USA,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152832PMC
March 2018

Infections, genetic and environmental factors in pathogenesis of autoimmune thyroid diseases.

Microb Pathog 2018 Mar 8;116:279-288. Epub 2018 Jan 8.

Department of Pathology, Government Medical College, Haldwani, Nainital, Uttarakhand, India.

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http://dx.doi.org/10.1016/j.micpath.2018.01.004DOI Listing
March 2018

Pyranocarbazoles from Murraya koenigii (L.) Spreng. as antimicrobial agents.

Nat Prod Res 2018 Feb 3;32(4):430-434. Epub 2017 Apr 3.

a Sophisticated Analytical Instrument Facility , CSIR-Central Drug Research Institute , Lucknow , India.

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http://dx.doi.org/10.1080/14786419.2017.1308363DOI Listing
February 2018

Pathway analysis of differentially expressed genes in Mycobacterium bovis challenged bovine macrophages.

Microb Pathog 2018 Feb 29;115:343-352. Epub 2017 Nov 29.

ICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Tajganj, Agra, U.P., India.

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http://dx.doi.org/10.1016/j.micpath.2017.11.065DOI Listing
February 2018

Differential gene expression in Mycobacterium bovis challenged monocyte-derived macrophages of cattle.

Microb Pathog 2017 Dec 21;113:480-489. Epub 2017 Nov 21.

Division of Animal Genetics, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, U.P., India.

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http://dx.doi.org/10.1016/j.micpath.2017.11.030DOI Listing
December 2017

Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect.

Proc Natl Acad Sci U S A 2017 10 9;114(43):11440-11445. Epub 2017 Oct 9.

Department of Biological Sciences, Indian Institute of Science Education and Research, Bhopal, Madhya Pradesh 462066, India;

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http://dx.doi.org/10.1073/pnas.1708447114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664520PMC
October 2017

A saga of cancer epigenetics: linking epigenetics to alternative splicing.

Biochem J 2017 03 7;474(6):885-896. Epub 2017 Mar 7.

Epigenetics and RNA Processing Laboratory (ERPL), Department of Biological Sciences, Indian Institute of Science Education and Research Bhopal (IISERB), Bhopal, Madhya Pradesh, India

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http://dx.doi.org/10.1042/BCJ20161047DOI Listing
March 2017

Intramolecular C-C Friedel-Crafts Arylation: Substrate- and Condition-Controlled Divergent Synthesis of Fused-β-carbolines.

Org Lett 2016 12 22;18(23):6010-6013. Epub 2016 Nov 22.

Academy of Scientific and Innovative Research, New Delhi-110025, India.

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http://dx.doi.org/10.1021/acs.orglett.6b02794DOI Listing
December 2016

Rapid screening and quantitative determination of bioactive compounds from fruit extracts of Myristica species and their in vitro antiproliferative activity.

Food Chem 2016 Nov 13;211:483-93. Epub 2016 May 13.

Sophisticated Analytical Instrument Facility, CSIR-Central Drug Research Institute, Lucknow 226031, Uttar Pradesh, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110025, India. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2016.05.065DOI Listing
November 2016

Evolutionary and bioinformatic analysis of the spike glycoprotein gene of H120 vaccine strain protectotype of infectious bronchitis virus from India.

Biotechnol Appl Biochem 2016 Jan-Feb;63(1):106-12

R-DNA Laboratory, Division of Veterinary Biotechnology, Indian Veterinary Research Institute, Izatnagar, Bareilly, India.

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http://doi.wiley.com/10.1002/bab.1298
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http://dx.doi.org/10.1002/bab.1298DOI Listing
October 2016

Obesity-initiated metabolic syndrome promotes urinary voiding dysfunction in a mouse model.

Prostate 2016 08 4;76(11):964-76. Epub 2016 Apr 4.

Department of Urology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio.

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http://dx.doi.org/10.1002/pros.23185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946024PMC
August 2016

Recovery of Ga(III) by Raw and Alkali Treated Citrus limetta Peels.

Int Sch Res Notices 2014 24;2014:968402. Epub 2014 Jul 24.

Department of Fibres and Textile Processing Technology, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga, Mumbai 400019, India.

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http://dx.doi.org/10.1155/2014/968402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897132PMC
July 2016

Synthesis of S-(-)-5,6-Dihydrocanthin-4-ones via a Triple Cooperative Catalysis-Mediated Domino Reaction.

J Org Chem 2016 06 17;81(11):4751-61. Epub 2016 May 17.

Academy of Scientific and Innovative Research , New Delhi 110025, India.

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http://dx.doi.org/10.1021/acs.joc.6b00613DOI Listing
June 2016

One-Pot Copper(I)-Catalyzed Ligand/Base-Free Tandem Cyclooxidative Synthesis of Quinazolinones.

J Org Chem 2016 06 1;81(12):5046-55. Epub 2016 Jun 1.

Medicinal and Process Chemistry Division, ‡Sophisticated Analytical Instrument Facility, CSIR-Central Drug Research Institute (CSIR-CDRI) , Sector 10, Jankipuram Extension, Sitapur Road, Lucknow-226031, India.

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http://dx.doi.org/10.1021/acs.joc.6b00599DOI Listing
June 2016

Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice.

PLoS One 2015 17;10(9):e0138710. Epub 2015 Sep 17.

Department of Urology, Case Western Reserve University, Cleveland, Ohio, United States of America; The Urology Institute, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America; Department of Nutrition, Case Western Reserve University, Cleveland, Ohio, United States of America; Division of General Medical Sciences, Case Comprehensive Cancer Center, Cleveland, Ohio, United States of America; Department of Urology, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138710PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574560PMC
May 2016

Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents.

J Nat Prod 2016 05 3;79(5):1276-84. Epub 2016 May 3.

Division of Medicinal and Process Chemistry, ‡Division of Biochemistry, §Division of Pharmacokinetics and Metabolism, ∥Sophisticated Analytical Instrument Facility, and ⊥Division of Botany, CSIR-Central Drug Research Institute , Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031, India.

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http://dx.doi.org/10.1021/acs.jnatprod.5b00883DOI Listing
May 2016

TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing.

EMBO J 2016 Feb 28;35(3):335-55. Epub 2015 Dec 28.

Center for Cancer Research, Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, Bethesda, MD, USA

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http://dx.doi.org/10.15252/embj.201593235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741300PMC
February 2016

Identification of β-Amino alcohol grafted 1,4,5 trisubstituted 1,2,3-triazoles as potent antimalarial agents.

Eur J Med Chem 2016 Feb 23;109:187-98. Epub 2015 Dec 23.

Medicinal and Process Chemistry Division, CSIR- Central Drug Research Institute (CSIR-CDRI), Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110001, India. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2015.12.038DOI Listing
February 2016

Identification of gallic acid based glycoconjugates as a novel tubulin polymerization inhibitors.

Org Biomol Chem 2016 Jan 11;14(4):1338-58. Epub 2015 Dec 11.

Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031, India.

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http://dx.doi.org/10.1039/c5ob02113hDOI Listing
January 2016

Genetic diversity and population structure analysis between Indian red jungle fowl and domestic chicken using microsatellite markers.

Anim Biotechnol 2015 ;26(3):201-10

a Avian Genetics and Breeding , Central Avian Research Institute , Izatnagar , Uttar Pradesh , India.

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http://www.tandfonline.com/doi/full/10.1080/10495398.2014.98
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http://dx.doi.org/10.1080/10495398.2014.983645DOI Listing
November 2015

Protective effects of recombinant glycoprotein D based prime boost approach against duck enteritis virus in mice model.

Microb Pathog 2015 Nov 15;88:78-86. Epub 2015 Jul 15.

Recombinant DNA Laboratory, Division of Veterinary Biotechnology, Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh 243122, India.

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http://dx.doi.org/10.1016/j.micpath.2015.07.008DOI Listing
November 2015

Integrated genomic analyses identify KDM1A's role in cell proliferation via modulating E2F signaling activity and associate with poor clinical outcome in oral cancer.

Cancer Lett 2015 Oct 28;367(2):162-72. Epub 2015 Jul 28.

Epigenetics and RNA Processing Laboratory (ERPL), Indian Institute of Science Education and Research Bhopal (IISERB), Madhya Pradesh, India. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2015.07.022DOI Listing
October 2015

Apigenin blocks IKKα activation and suppresses prostate cancer progression.

Oncotarget 2015 Oct;6(31):31216-32

Department of Urology, Case Western Reserve University & University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.18632/oncotarget.5157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741599PMC
October 2015

Transition-Metal-Free C-3 Arylation of Quinoline-4-ones with Arylhydrazines.

J Org Chem 2015 May 28;80(10):5369-76. Epub 2015 Apr 28.

†Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India.

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http://dx.doi.org/10.1021/acs.joc.5b00739DOI Listing
May 2015

Adaptation and growth kinetics study of an Indian isolate of virulent duck enteritis virus in Vero cells.

Microb Pathog 2015 Jan 13;78:14-9. Epub 2014 Nov 13.

Recombinant DNA Laboratory, Division of Veterinary Biotechnology, Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.

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http://dx.doi.org/10.1016/j.micpath.2014.11.008DOI Listing
January 2015

Synergistic simvastatin and metformin combination chemotherapy for osseous metastatic castration-resistant prostate cancer.

Mol Cancer Ther 2014 Oct 13;13(10):2288-302. Epub 2014 Aug 13.

Department of Urology, Case Western Reserve University, and The Urology Institute, University Hospitals Case Medical Center, Cleveland, Ohio. Department of Nutrition, Case Western Reserve University, Cleveland, Ohio. Division of General Medical Sciences, Case Comprehensive Cancer Center, Cleveland, Ohio.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185215PMC
October 2014

Synthesis and anticancer activity of γ-(triazolyl ethylidene)butenolides and polyfunctional pyrrolinones.

Eur J Med Chem 2014 Jul 15;82:106-19. Epub 2014 May 15.

Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research, New Delhi 110001, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234140045
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http://dx.doi.org/10.1016/j.ejmech.2014.05.042DOI Listing
July 2014

Apigenin induces apoptosis by targeting inhibitor of apoptosis proteins and Ku70-Bax interaction in prostate cancer.

Apoptosis 2014 May;19(5):883-94

Department of Urology, Case Western Reserve University & The Urology Institute, University Hospitals Case Medical Center, 10900 Euclid Avenue, Cleveland, OH, 44106, USA.

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http://dx.doi.org/10.1007/s10495-014-0971-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997183PMC
May 2014

Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway.

Carcinogenesis 2014 Feb 25;35(2):452-60. Epub 2013 Sep 25.

Department of Urology, Case Western Reserve University and The Urology Institute, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.

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http://carcin.oxfordjournals.org/content/35/2/452.full.pdf
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http://www.carcin.oxfordjournals.org/cgi/doi/10.1093/carcin/
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http://dx.doi.org/10.1093/carcin/bgt316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983429PMC
February 2014

FOXO3a: A Potential Target in Prostate Cancer.

Authors:
Sanjeev Shukla

Austin J Urol 2014;1(1)

Department of Urology, Case Western Reserve University, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288772PMC
January 2014

Deregulation of FoxO3a accelerates prostate cancer progression in TRAMP mice.

Prostate 2013 Oct 13;73(14):1507-17. Epub 2013 Jun 13.

Department of Urology, Case Western Reserve University & The Urology Institute, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1002/pros.22698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018753PMC
October 2013

Synthesis of triazolo isoquinolines and isochromenes from 2-alkynylbenzaldehyde via domino reactions under transition-metal-free conditions.

J Org Chem 2013 Oct 10;78(20):10476-84. Epub 2013 Oct 10.

Medicinal and Process Chemistry Division and ‡Sophisticated Analytical Instrumental Facility, CSIR-Central Drug Research Institute , Lucknow 226001, India.

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http://dx.doi.org/10.1021/jo401929qDOI Listing
October 2013

Detection and identification of globally distributed mycobacterial fish pathogens in some ornamental fish in India.

Folia Microbiol (Praha) 2013 Sep 30;58(5):429-36. Epub 2013 Jan 30.

Department of Biotechnology, Integral University, Lucknow, Uttar Pradesh, India, 226026.

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http://dx.doi.org/10.1007/s12223-013-0225-yDOI Listing
September 2013

Upregulation of SATB1 is associated with prostate cancer aggressiveness and disease progression.

PLoS One 2013 7;8(1):e53527. Epub 2013 Jan 7.

Department of Urology, Case Western Reserve University & University Hospitals Case Medical Center, Cleveland, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053527PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538595PMC
July 2013

Prognostic utility of autoantibodies to α-enolase and Hsp70 for cancer of the gingivo-buccal complex using immunoproteomics.

Proteomics Clin Appl 2013 Jun 1;7(5-6):392-402. Epub 2013 Mar 1.

Advanced Centre for Treatment, Research and Education in Cancer ACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India.

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http://doi.wiley.com/10.1002/prca.201200081
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http://dx.doi.org/10.1002/prca.201200081DOI Listing
June 2013

A strategy for the synthesis of anthraquinone-based aryl-C-glycosides.

J Org Chem 2013 May 6;78(10):4685-96. Epub 2013 May 6.

Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow 226001, India.

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http://dx.doi.org/10.1021/jo302589tDOI Listing
May 2013

Chamomile confers protection against hydrogen peroxide-induced toxicity through activation of Nrf2-mediated defense response.

Phytother Res 2013 Jan 18;27(1):118-25. Epub 2012 Apr 18.

Department of Urology, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1002/ptr.4701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019961PMC
January 2013

Plant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: in vitro and in vivo study.

Mol Carcinog 2012 Dec 17;51(12):952-62. Epub 2011 Oct 17.

Department of Urology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1002/mc.20866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019962PMC
December 2012

One pot efficient diversity oriented synthesis of polyfunctional styryl thiazolopyrimidines and their bio-evaluation as antimalarial and anti-HIV agents.

Eur J Med Chem 2012 Sep 23;55:195-204. Epub 2012 Jul 23.

Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, India.

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http://dx.doi.org/10.1016/j.ejmech.2012.07.018DOI Listing
September 2012

Co-transcriptional regulation of alternative pre-mRNA splicing.

Biochim Biophys Acta 2012 Jul 2;1819(7):673-83. Epub 2012 Feb 2.

Mouse Cancer Genetics Program, NCI- Frederick, NIH, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1016/j.bbagrm.2012.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371144PMC
July 2012

Apigenin attenuates insulin-like growth factor-I signaling in an autochthonous mouse prostate cancer model.

Pharm Res 2012 Jun 3;29(6):1506-17. Epub 2011 Dec 3.

Department of Urology, Case Western Reserve University, 2109 Adelbert Road, Wood Research Tower, RTG01, Cleveland, Ohio 44106, USA.

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http://link.springer.com/10.1007/s11095-011-0625-0
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http://dx.doi.org/10.1007/s11095-011-0625-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017263PMC
June 2012

Induction of heme oxygenase-1 by chamomile protects murine macrophages against oxidative stress.

Life Sci 2012 Jun 5;90(25-26):1027-33. Epub 2012 Jun 5.

Department of Urology, Case Western Reserve University, Cleveland, OH 44106, United States.

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http://dx.doi.org/10.1016/j.lfs.2012.05.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389181PMC
June 2012

High-fat diet activates pro-inflammatory response in the prostate through association of Stat-3 and NF-κB.

Prostate 2012 Feb 20;72(3):233-43. Epub 2011 May 20.

Department of Urology, Case Western Reserve University & The Urology Institute, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1002/pros.21425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161175PMC
February 2012

CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing.

Nature 2011 Nov;479(7371):74-9

Center for Cancer Research, Mouse Cancer Genetics Program, National Cancer Institute at Frederick, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1038/nature10442DOI Listing
November 2011

High-fat diet increases NF-κB signaling in the prostate of reporter mice.

Prostate 2011 Feb;71(2):147-56

Department of Urology, Case Western Reserve University & University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA.

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http://doi.wiley.com/10.1002/pros.21230
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http://dx.doi.org/10.1002/pros.21230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019972PMC
February 2011

Chamomile: an anti-inflammatory agent inhibits inducible nitric oxide synthase expression by blocking RelA/p65 activity.

Int J Mol Med 2010 Dec;26(6):935-40

Department of Urology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982259PMC
http://dx.doi.org/10.3892/ijmm_00000545DOI Listing
December 2010

Structural determinants of host defense peptides for antimicrobial activity and target cell selectivity.

Biochimie 2010 Sep 25;92(9):1236-41. Epub 2010 Feb 25.

Department of Biochemistry, Kansas State University, Manhattan, KS 66506, USA.

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http://dx.doi.org/10.1016/j.biochi.2010.02.023DOI Listing
September 2010

Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells.

Int J Cancer 2010 Jun;126(11):2520-33

Department of Urology, The James and Eilleen Dicke Research Laboratory, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, OH, USA.

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http://dx.doi.org/10.1002/ijc.24988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874465PMC
June 2010

Apigenin: a promising molecule for cancer prevention.

Pharm Res 2010 Jun 20;27(6):962-78. Epub 2010 Mar 20.

Department of Urology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1007/s11095-010-0089-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874462PMC
June 2010

Immunoproteomics reveals that cancer of the tongue and the gingivobuccal complex exhibit differential autoantibody response.

Cancer Biomark 2009 ;5(3):127-35

Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai, India.

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http://dx.doi.org/10.3233/CBM-2009-0604DOI Listing
July 2009

Deregulation of FOXO3A during prostate cancer progression.

Int J Oncol 2009 Jun;34(6):1613-20

Department of Urology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, OH 44106, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683383PMC
http://dx.doi.org/10.3892/ijo_00000291DOI Listing
June 2009

Il-1 beta-induced post-transition effect of NF-kappaB provides time-dependent wave of signals for initial phase of intrapostatic inflammation.

Prostate 2009 May;69(6):633-43

Department of Urology, Case Western Reserve University, Case Medical Center & University Hospitals of Cleveland, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1002/pros.20916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669895PMC
May 2009

Apigenin suppresses insulin-like growth factor I receptor signaling in human prostate cancer: an in vitro and in vivo study.

Mol Carcinog 2009 Mar;48(3):243-252

Department of Urology, Case Western Reserve University, Cleveland, Ohio.

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http://dx.doi.org/10.1002/mc.20475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647985PMC
March 2009

Physician compact: a tool for enhancing physician satisfaction and improving communication.

Physician Exec 2009 Jan-Feb;35(1):46-9

Wheaton Franciscan Medical Group, Milwaukee, Wis, USA.

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March 2009

Betulinic acid suppresses constitutive and TNFalpha-induced NF-kappaB activation and induces apoptosis in human prostate carcinoma PC-3 cells.

Mol Carcinog 2008 Dec;47(12):964-73

Department of Urology, The James & Eillen Dicke Research Laboratory, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://doi.wiley.com/10.1002/mc.20447
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http://dx.doi.org/10.1002/mc.20447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864721PMC
December 2008

Plant flavonoid apigenin inactivates Akt to trigger apoptosis in human prostate cancer: an in vitro and in vivo study.

Carcinogenesis 2008 Nov 25;29(11):2210-7. Epub 2008 Aug 25.

Department of Urology, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1093/carcin/bgn201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577719PMC
November 2008

Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation.

Free Radic Biol Med 2008 May 26;44(10):1833-45. Epub 2008 Feb 26.

Department of Urology, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S089158490800095
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http://dx.doi.org/10.1016/j.freeradbiomed.2008.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538676PMC
May 2008

Molecular imaging of NF-kappaB in prostate tissue after systemic administration of IL-1 beta.

Prostate 2008 Jan;68(1):34-41

Department of Urology, Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1002/pros.20666DOI Listing
January 2008

Tumor antigens eliciting autoantibody response in cancer of gingivo-buccal complex.

Proteomics Clin Appl 2007 Dec;1(12):1592-604

Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India.

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http://doi.wiley.com/10.1002/prca.200700206
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http://dx.doi.org/10.1002/prca.200700206DOI Listing
December 2007

Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion.

Int J Cancer 2007 Oct;121(7):1424-32

Department of Urology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland 44106, OH, USA.

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http://dx.doi.org/10.1002/ijc.22862DOI Listing
October 2007

Blockade of beta-catenin signaling by plant flavonoid apigenin suppresses prostate carcinogenesis in TRAMP mice.

Cancer Res 2007 Jul;67(14):6925-35

Department of Urology, Case Western Reserve University and University Hospitals Case Medical Center, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-07-0717DOI Listing
July 2007

Apigenin-induced cell cycle arrest is mediated by modulation of MAPK, PI3K-Akt, and loss of cyclin D1 associated retinoblastoma dephosphorylation in human prostate cancer cells.

Cell Cycle 2007 May 15;6(9):1102-14. Epub 2007 May 15.

Department of Urology, Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA.

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http://www.tandfonline.com/doi/abs/10.4161/cc.6.9.4146
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http://dx.doi.org/10.4161/cc.6.9.4146DOI Listing
May 2007

Apigenin and cancer chemoprevention: progress, potential and promise (review).

Int J Oncol 2007 Jan;30(1):233-45

Department of Urology, Case Western Reserve University, Cleveland, OH 44106, USA.

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January 2007

Dietary agents in the chemoprevention of prostate cancer.

Nutr Cancer 2005 ;53(1):18-32

Department of Urology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1207/s15327914nc5301_3DOI Listing
June 2006

Molecular targets for apigenin-induced cell cycle arrest and apoptosis in prostate cancer cell xenograft.

Mol Cancer Ther 2006 Apr;5(4):843-52

Department of Urology, The James and Eilleen Dicke Research Laboratory, Case Western Reserve University and University Hospitals of Cleveland, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-05-0370DOI Listing
April 2006

Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice.

FASEB J 2005 Dec 17;19(14):2042-4. Epub 2005 Oct 17.

Department of Urology, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1096/fj.05-3740fjeDOI Listing
December 2005

Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model.

Prostate 2005 Aug;64(3):224-39

Department of Urology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, Ohio.

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http://doi.wiley.com/10.1002/pros.20217
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http://dx.doi.org/10.1002/pros.20217DOI Listing
August 2005

Nuclear factor-kappaB/p65 (Rel A) is constitutively activated in human prostate adenocarcinoma and correlates with disease progression.

Neoplasia 2004 Jul-Aug;6(4):390-400

Department of Urology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, USA.

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http://dx.doi.org/10.1593/neo.04112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502112PMC
April 2005

Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.

Clin Cancer Res 2004 May;10(9):3169-78

Department of Urology, The James and Eillen Dicke Research Laboratory, Case Western Reserve University, Cleveland, OH 44106, USA.

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May 2004

Molecular mechanisms for apigenin-induced cell-cycle arrest and apoptosis of hormone refractory human prostate carcinoma DU145 cells.

Mol Carcinog 2004 Feb;39(2):114-26

Department of Urology, The James and Eilleen Dicke Research Laboratory, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://doi.wiley.com/10.1002/mc.10168
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February 2004

Effect of herbal hypoglycemic agents on oxidative stress and antioxidant status in diabetic rats.

Indian J Clin Biochem 2003 Jul;18(2):8-15

Department of Biochemistry, C.S.M. Medical University (upgraded King George's Medical College), 226003 Lucknow, U.P. India.

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http://dx.doi.org/10.1007/BF02867361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3453893PMC
July 2003